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The map label for this gene is coaD

Identifier: 113475264

GI number: 113475264

Start: 2405021

End: 2405527

Strand: Direct

Name: coaD

Synonym: Tery_1572

Alternate gene names: 113475264

Gene position: 2405021-2405527 (Clockwise)

Preceding gene: 113475260

Following gene: 113475265

Centisome position: 31.03

GC content: 36.09

Gene sequence:

>507_bases
GTGATTGCAATTTATCCAGGCAGTTTCGACCCCATTACCTTAGGTCATATAGATATTATAGAAAGAGGCTGCAACCTGTT
TGAAAAAGTAATTGTAGCTGTCCTGCGAAATCAAAGTAAGACCTCTTTATTTACTATTGAGCAGCGTTTGAATCAAATTT
GTCATTCCACAAAACACCTGCTTAATGTAGAGGTAGCCAGTTTTGATGGTTTAGCGGTAAACTATGCAAAAATGCAACAG
GCTAAAGTCCTAATTCGAGGTCTACGAGTTCTTTCAGATTTTGAAAAAGAATTACAGATGGCCCATACTAATAAAACCTT
GTCACCTGAAATAGAGACAGTTTTTTTAGCTACCTCTAATGAATATAGTTTTTTAAGTAGTAGTGTAGTTAAAGAAATTG
CTGTTTTTGGTGGCTCAGTAGATCATCTCGTTCCCCAGCACATTGCTATTGATATTTATAAATGTTACGACAAAACTCAG
CCAAAGCCAATATTGAACCAGAGGTAA

Upstream 100 bases:

>100_bases
GAATCATATTAATTTTTATATTAAACACCCAGCTTTTAAAAGTTGAGTAAATTTGGGAAAAACCTTGCTAAAATACTTTA
GTAACTCTTAAATACGACCC

Downstream 100 bases:

>100_bases
ATGGGCAAAATGTCGAGAGTCAACCTGCCAGTGGTTCCCCTGGAGTAGATATCCAGCGAGAACTGAATAGGCTGGAAGAG
ATTATTCTTGATAGTCCTAG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MIAIYPGSFDPITLGHIDIIERGCNLFEKVIVAVLRNQSKTSLFTIEQRLNQICHSTKHLLNVEVASFDGLAVNYAKMQQ
AKVLIRGLRVLSDFEKELQMAHTNKTLSPEIETVFLATSNEYSFLSSSVVKEIAVFGGSVDHLVPQHIAIDIYKCYDKTQ
PKPILNQR

Sequences:

>Translated_168_residues
MIAIYPGSFDPITLGHIDIIERGCNLFEKVIVAVLRNQSKTSLFTIEQRLNQICHSTKHLLNVEVASFDGLAVNYAKMQQ
AKVLIRGLRVLSDFEKELQMAHTNKTLSPEIETVFLATSNEYSFLSSSVVKEIAVFGGSVDHLVPQHIAIDIYKCYDKTQ
PKPILNQR
>Mature_168_residues
MIAIYPGSFDPITLGHIDIIERGCNLFEKVIVAVLRNQSKTSLFTIEQRLNQICHSTKHLLNVEVASFDGLAVNYAKMQQ
AKVLIRGLRVLSDFEKELQMAHTNKTLSPEIETVFLATSNEYSFLSSSVVKEIAVFGGSVDHLVPQHIAIDIYKCYDKTQ
PKPILNQR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=146, Percent_Identity=52.0547945205479, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_TRIEI (Q115H2)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_721325.1
- ProteinModelPortal:   Q115H2
- SMR:   Q115H2
- STRING:   Q115H2
- GeneID:   4242130
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_1572
- NMPDR:   fig|203124.1.peg.5675
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q115H2
- BioCyc:   TERY203124:TERY_1572-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18904; Mature: 18904

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAIYPGSFDPITLGHIDIIERGCNLFEKVIVAVLRNQSKTSLFTIEQRLNQICHSTKHL
CEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LNVEVASFDGLAVNYAKMQQAKVLIRGLRVLSDFEKELQMAHTNKTLSPEIETVFLATSN
HEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECC
EYSFLSSSVVKEIAVFGGSVDHLVPQHIAIDIYKCYDKTQPKPILNQR
CHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIAIYPGSFDPITLGHIDIIERGCNLFEKVIVAVLRNQSKTSLFTIEQRLNQICHSTKHL
CEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LNVEVASFDGLAVNYAKMQQAKVLIRGLRVLSDFEKELQMAHTNKTLSPEIETVFLATSN
HEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECC
EYSFLSSSVVKEIAVFGGSVDHLVPQHIAIDIYKCYDKTQPKPILNQR
CHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA