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The map label for this gene is dspA [H]

Identifier: 113475172

GI number: 113475172

Start: 2228505

End: 2230655

Strand: Reverse

Name: dspA [H]

Synonym: Tery_1470

Alternate gene names: 113475172

Gene position: 2230655-2228505 (Counterclockwise)

Preceding gene: 113475173

Following gene: 113475170

Centisome position: 28.78

GC content: 34.4

Gene sequence:

>2151_bases
ATGCTTCCCCTCCTCAAAAAAATCGGAGAAATTATTGCTAATTGGTGGTCTGAGTTTACCCTCCAGAGCAAACTTATGGC
AGTTATTACCCTGATAGTATCTTTGCTAATGAGTAGCTTAAGCTTCTGGGCAGTAAATACTATTCAGGAGGATGCTCGCC
TGAATGACACTCGTTATGGTCGAGACCTGGGTTTATTATTAGCCGCTAATGTCGCCCCACTTATGGCAGAAGGCAATCGC
AACGAAGTAGCCCGTTTTTCCAGACTTTTCTACAAAAGTACATCTAGTGTACGTTATATGCTCTATGCTGATGAAGAAGG
AAAGATTTTCTTAGGTATTCCCTTCTCAGAATCTGAGGTAAAAACATCTCTTACTCTCCGTCGTCGTATTCAACTGCCAG
AAGATTTTATGGCCAATATAGAGGATGAAAAATATTCAGCTTTGCCTCTAGTGCGACAACATTTAACTCCTAATGGTCAA
TTAACGGATGTTTTTGTTCCCCTTATTGATGAAAGTAAATATTTAGGAGTTTTAGCAGTTGGAATTAATCCTAATCCTAC
TGTGGTTGTCTCTTCAAATCTGACTAGAGATGTAACTTTAGCAGTTTTTGTTTCGATCTGGGCAATGGTAATTTTAGGTG
CAGTTGTTCATGCTTTGATTATTACTAAACCAATCAAGAAATTATCGGAAGGTGTCAAAAATATTGCTCAGGGAAATTTT
AAACAAAGGATAGACTTATCTTTTGGAAGAGAACTAGGGGAACTGATTTTGAGCTTTAATGAAATGGCGGAACAGTTAGA
AAATTATAAGAAGCAAAATATTGAAAAATTAACGGCAGAAAAAGCAAAGTTAGAAACCTTAGTTTCCACAATTGCTGATG
GCGCTTTATTGTTAGATGCTAATTTACAATTGATTTTAGTTAATCCAACTGCTCGGCGTATTTTTAGTTGGGAAGAAAAA
AAGGTTATTGGTGGAAAGGTGACGGATAATTTACCTGTAGCTGTACAGATGGAATTAAATAGACCACTTTATCAAATAGC
TACAGGGGAAATAGAAGGGGGTGAATATCGTTGTACTTTAGATGAACCAAATAAACGTACAATTAGAGTTTTATTAACAA
CTGTTCTTTTATACAGAGCATCAGGTACAGAATCTCTTTGTAAAAGTTGTATTTATGATGCATACGATAGTTGTAGTTCT
GCTAATCGTCCTGTAGTTTATGAATGTACACTTTATGAAAATAAGCTAGGAACAGATTTTATTTCTCCATACCGAAATAG
TCTTAAAGGAATTGCTATGACTGTACAAGATATTACTAGAGAAGTAGAATTAAATGACGCAAAAAGTCAGTTTATTAGTA
ATGTCTCCCATGAATTAAGAACCCCTTTATTTAATATTAAATCTTTCATCGAAACTTTGCATGAATATGGGGAAGATTTA
AGTGAAGTAGAAAGACGAGAATTTTTAGAGACTGCCAATCATGAAACAGATCGTTTGACTCGTTTAGTTAATGATGTATT
GGATTTAAGTCGTCTAGAATCTTGTATGATTTATCACCTAAATGCTGTTGATGTTGCTCAACCAATAGAACAAACTTTAA
GAACTTATCATCTTAATGCTAAAGATAAAAAAATAGAATTAAATTATGATATAGAATCTAACTTGCCTACTGTAGTTGGT
CATTATGATTTATTACTACAAGTATTTGCTAATTTGGTAGGCAATGCTATGAAGTTTACTGAACCAGGAGGTAGAATAGT
AATTAGAGCTTATCTGTTAGAATCTGATATAGAAATTGAACAAATAGAACAAGGAGGATGGATAGTTTCTCCTCCTCCAC
CTCGACCAACAGAACTAAATTTAAAATCTAATAATCAGTTTGTCAGAATTGAAATTTCAGATACAGGAAGTGGTATTGAA
CCTGAAGACCAAGAAGCTATTTTTGAAAGGTTTTTCCGAGTTGAAAATCGTGTTCATACTTTGGAAGGAACAGGTTTAGG
TTTGTCTATTGTTAGAAATATTATTGATAAGCATCATAGTAAGGTTAACCTCGTAAGTGAACTTGGTGTAGGCACAACTT
TTTGGTTTGATTTAGCAGTATTTGAAGAAAGGTCAGTACCAGAAGAAAATCAGTTATTGGAAGTACCTTAA

Upstream 100 bases:

>100_bases
ACCTTTCGGTAAAGCCTAACTACCCCAGTTAATATAGAGTAGAATTGAGAAGTAATCTTAACTTTTATTGACTTTTAAAT
TTTGACTTTTGACTTAAAAA

Downstream 100 bases:

>100_bases
ATATAGCTCTCAGTTATCACCTGAAGTTAGAAGTTATAAGTTTATTATTGTCGTGCTATGGCATACCTAAAAATAATGGT
CTTTGTAGAACGAAGTGCAG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MLPLLKKIGEIIANWWSEFTLQSKLMAVITLIVSLLMSSLSFWAVNTIQEDARLNDTRYGRDLGLLLAANVAPLMAEGNR
NEVARFSRLFYKSTSSVRYMLYADEEGKIFLGIPFSESEVKTSLTLRRRIQLPEDFMANIEDEKYSALPLVRQHLTPNGQ
LTDVFVPLIDESKYLGVLAVGINPNPTVVVSSNLTRDVTLAVFVSIWAMVILGAVVHALIITKPIKKLSEGVKNIAQGNF
KQRIDLSFGRELGELILSFNEMAEQLENYKKQNIEKLTAEKAKLETLVSTIADGALLLDANLQLILVNPTARRIFSWEEK
KVIGGKVTDNLPVAVQMELNRPLYQIATGEIEGGEYRCTLDEPNKRTIRVLLTTVLLYRASGTESLCKSCIYDAYDSCSS
ANRPVVYECTLYENKLGTDFISPYRNSLKGIAMTVQDITREVELNDAKSQFISNVSHELRTPLFNIKSFIETLHEYGEDL
SEVERREFLETANHETDRLTRLVNDVLDLSRLESCMIYHLNAVDVAQPIEQTLRTYHLNAKDKKIELNYDIESNLPTVVG
HYDLLLQVFANLVGNAMKFTEPGGRIVIRAYLLESDIEIEQIEQGGWIVSPPPPRPTELNLKSNNQFVRIEISDTGSGIE
PEDQEAIFERFFRVENRVHTLEGTGLGLSIVRNIIDKHHSKVNLVSELGVGTTFWFDLAVFEERSVPEENQLLEVP

Sequences:

>Translated_716_residues
MLPLLKKIGEIIANWWSEFTLQSKLMAVITLIVSLLMSSLSFWAVNTIQEDARLNDTRYGRDLGLLLAANVAPLMAEGNR
NEVARFSRLFYKSTSSVRYMLYADEEGKIFLGIPFSESEVKTSLTLRRRIQLPEDFMANIEDEKYSALPLVRQHLTPNGQ
LTDVFVPLIDESKYLGVLAVGINPNPTVVVSSNLTRDVTLAVFVSIWAMVILGAVVHALIITKPIKKLSEGVKNIAQGNF
KQRIDLSFGRELGELILSFNEMAEQLENYKKQNIEKLTAEKAKLETLVSTIADGALLLDANLQLILVNPTARRIFSWEEK
KVIGGKVTDNLPVAVQMELNRPLYQIATGEIEGGEYRCTLDEPNKRTIRVLLTTVLLYRASGTESLCKSCIYDAYDSCSS
ANRPVVYECTLYENKLGTDFISPYRNSLKGIAMTVQDITREVELNDAKSQFISNVSHELRTPLFNIKSFIETLHEYGEDL
SEVERREFLETANHETDRLTRLVNDVLDLSRLESCMIYHLNAVDVAQPIEQTLRTYHLNAKDKKIELNYDIESNLPTVVG
HYDLLLQVFANLVGNAMKFTEPGGRIVIRAYLLESDIEIEQIEQGGWIVSPPPPRPTELNLKSNNQFVRIEISDTGSGIE
PEDQEAIFERFFRVENRVHTLEGTGLGLSIVRNIIDKHHSKVNLVSELGVGTTFWFDLAVFEERSVPEENQLLEVP
>Mature_716_residues
MLPLLKKIGEIIANWWSEFTLQSKLMAVITLIVSLLMSSLSFWAVNTIQEDARLNDTRYGRDLGLLLAANVAPLMAEGNR
NEVARFSRLFYKSTSSVRYMLYADEEGKIFLGIPFSESEVKTSLTLRRRIQLPEDFMANIEDEKYSALPLVRQHLTPNGQ
LTDVFVPLIDESKYLGVLAVGINPNPTVVVSSNLTRDVTLAVFVSIWAMVILGAVVHALIITKPIKKLSEGVKNIAQGNF
KQRIDLSFGRELGELILSFNEMAEQLENYKKQNIEKLTAEKAKLETLVSTIADGALLLDANLQLILVNPTARRIFSWEEK
KVIGGKVTDNLPVAVQMELNRPLYQIATGEIEGGEYRCTLDEPNKRTIRVLLTTVLLYRASGTESLCKSCIYDAYDSCSS
ANRPVVYECTLYENKLGTDFISPYRNSLKGIAMTVQDITREVELNDAKSQFISNVSHELRTPLFNIKSFIETLHEYGEDL
SEVERREFLETANHETDRLTRLVNDVLDLSRLESCMIYHLNAVDVAQPIEQTLRTYHLNAKDKKIELNYDIESNLPTVVG
HYDLLLQVFANLVGNAMKFTEPGGRIVIRAYLLESDIEIEQIEQGGWIVSPPPPRPTELNLKSNNQFVRIEISDTGSGIE
PEDQEAIFERFFRVENRVHTLEGTGLGLSIVRNIIDKHHSKVNLVSELGVGTTFWFDLAVFEERSVPEENQLLEVP

Specific function: Member Of The Two-Component Regulatory System Phor/Phob Involved In The Phosphate Regulon Genes Expression. Phor May Function As A Membrane-Associated Protein Kinase That Phosphorylates Phob In Response To Environmental Signals. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=278, Percent_Identity=30.5755395683453, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1789149, Length=264, Percent_Identity=30.6818181818182, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=323, Percent_Identity=28.1733746130031, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790436, Length=285, Percent_Identity=27.3684210526316, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788393, Length=260, Percent_Identity=24.6153846153846, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=256, Percent_Identity=25.390625, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI48994928, Length=283, Percent_Identity=26.5017667844523, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786783, Length=253, Percent_Identity=24.5059288537549, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=26.7441860465116, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80851; Mature: 80851

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLLKKIGEIIANWWSEFTLQSKLMAVITLIVSLLMSSLSFWAVNTIQEDARLNDTRYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RDLGLLLAANVAPLMAEGNRNEVARFSRLFYKSTSSVRYMLYADEEGKIFLGIPFSESEV
CCHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCHHHH
KTSLTLRRRIQLPEDFMANIEDEKYSALPLVRQHLTPNGQLTDVFVPLIDESKYLGVLAV
HHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEEEEE
GINPNPTVVVSSNLTRDVTLAVFVSIWAMVILGAVVHALIITKPIKKLSEGVKNIAQGNF
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KQRIDLSFGRELGELILSFNEMAEQLENYKKQNIEKLTAEKAKLETLVSTIADGALLLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
NLQLILVNPTARRIFSWEEKKVIGGKVTDNLPVAVQMELNRPLYQIATGEIEGGEYRCTL
CEEEEEECCHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCEEEEEE
DEPNKRTIRVLLTTVLLYRASGTESLCKSCIYDAYDSCSSANRPVVYECTLYENKLGTDF
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHH
ISPYRNSLKGIAMTVQDITREVELNDAKSQFISNVSHELRTPLFNIKSFIETLHEYGEDL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCH
SEVERREFLETANHETDRLTRLVNDVLDLSRLESCMIYHLNAVDVAQPIEQTLRTYHLNA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHEECCC
KDKKIELNYDIESNLPTVVGHYDLLLQVFANLVGNAMKFTEPGGRIVIRAYLLESDIEIE
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCCHH
QIEQGGWIVSPPPPRPTELNLKSNNQFVRIEISDTGSGIEPEDQEAIFERFFRVENRVHT
HHHCCCEEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEE
LEGTGLGLSIVRNIIDKHHSKVNLVSELGVGTTFWFDLAVFEERSVPEENQLLEVP
ECCCCCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEECCC
>Mature Secondary Structure
MLPLLKKIGEIIANWWSEFTLQSKLMAVITLIVSLLMSSLSFWAVNTIQEDARLNDTRYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RDLGLLLAANVAPLMAEGNRNEVARFSRLFYKSTSSVRYMLYADEEGKIFLGIPFSESEV
CCHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCHHHH
KTSLTLRRRIQLPEDFMANIEDEKYSALPLVRQHLTPNGQLTDVFVPLIDESKYLGVLAV
HHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEEEEE
GINPNPTVVVSSNLTRDVTLAVFVSIWAMVILGAVVHALIITKPIKKLSEGVKNIAQGNF
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KQRIDLSFGRELGELILSFNEMAEQLENYKKQNIEKLTAEKAKLETLVSTIADGALLLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
NLQLILVNPTARRIFSWEEKKVIGGKVTDNLPVAVQMELNRPLYQIATGEIEGGEYRCTL
CEEEEEECCHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCEEEEEE
DEPNKRTIRVLLTTVLLYRASGTESLCKSCIYDAYDSCSSANRPVVYECTLYENKLGTDF
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHH
ISPYRNSLKGIAMTVQDITREVELNDAKSQFISNVSHELRTPLFNIKSFIETLHEYGEDL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCH
SEVERREFLETANHETDRLTRLVNDVLDLSRLESCMIYHLNAVDVAQPIEQTLRTYHLNA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHEECCC
KDKKIELNYDIESNLPTVVGHYDLLLQVFANLVGNAMKFTEPGGRIVIRAYLLESDIEIE
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCCHH
QIEQGGWIVSPPPPRPTELNLKSNNQFVRIEISDTGSGIEPEDQEAIFERFFRVENRVHT
HHHCCCEEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEE
LEGTGLGLSIVRNIIDKHHSKVNLVSELGVGTTFWFDLAVFEERSVPEENQLLEVP
ECCCCCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]