Click here to switch to the map view.

The map label for this gene is tynA [C]

Identifier: 113475102

GI number: 113475102

Start: 2117278

End: 2119272

Strand: Reverse

Name: tynA [C]

Synonym: Tery_1383

Alternate gene names: 113475102

Gene position: 2119272-2117278 (Counterclockwise)

Preceding gene: 113475106

Following gene: 113475093

Centisome position: 27.35

GC content: 40.15

Gene sequence:

>1995_bases
ATGGAACTAAATATCTTAGAAAATAATGAAAACCCAATCTTATTAACCGATTCATTCACTCATATAGATAATTCATTAAT
TAAATTGAGTCAAATTTCAAGTGCTGAAAGTCATCCTCTAGATCCCTTAACAGCAGAAGAAATTGAAGCAACAGTTAAAA
TTATTGGAGAGCAACAACTCCTCAGTGAAGCAACATTTTTTCCTCGAATCGCCCTAAATGAACCGGCAAAAGAAAAAGTA
GTAACTCATACTCCCGGTACTCCCTTTGAGAGAGAAGCATTTGCTGTAGTATTTGATTCACAAGCAAATATTACCTATGA
AGCAGTAGTCGATTTAATTACTGGAGAAGTTGAAAGTTGGGAGCAAATCCCTAATGTATTTGTACAAATCCTCGATCCAG
ATGATTACGATGCCCTAGAAGAATTAACTGCCAGCGATCCAGAAGTTTTAGCTGCTCTGGAAAGGCGGAGAATTAATCCA
GACAATGTTTACTTTACAGGTTGGGCACCAGGTCCTCTAAGCCAAGAAGAAGCTGCCACAGGTTCTCGCTTGATTCGTGG
AATTCCCTATGTGATTGGAGATGACATTAACTTTTATGGACGACCTATTGAGGGGTTGCTTGTCACCGTCGATCTGACAA
ATAATCAAATTCTCAATGTCAGTGACTCGGGAAATATTCCTATTGCTGGTGATGCGGGATTTCGTGCAGATGAAATAGAC
TTGCGCGAGCCGCTACCACCATTAGAAATTGTTGAACCAGAAGGAGCAAGCTATGAATTTAATGGCAATCAAATAAGTTG
GGATAAATGGGATTTTCGTTACTCCATTGATCCTCGAACTGGGTTGGTATTGCACCAAGTTAGCTATGATGATCGCTCCA
TTCTTTATCGTGGTTCATTGTCTGAATTATCGGTTCCCTATGGTGATCCTGATGGAAATTGGAGGGTTAGAAATGCTTTA
GATGTAGGGGAATATAGTATAGGACGCTTTACTTATCCAATGGAAGTAGGCAGAGACATACCAGAAAATGCAAAGTTGTT
AGATGGGACTTTTGCTGATGATTTAGGAGAACCATATCTCTGGGAGGGAGCAGCAGCAATTTACGAACGGCAGGGTGGAC
TACTCTGGTCACATTTTGACTTTGACCTGACCGAAGAAATTGAATCTCGTCGTAGTCGAGAGCTAGTAATGCGGTCTATT
ATGACTATTGGTAACTACGATTATGCTGTTAACTGGGTATTTCAACAGGATGGGACATTAAAAGTTGAAGCTGATTTAAC
TGGAATTATTTTAGCTAAAGGTACAGAAGCAACCGATATGGAAACCCTAAGTGAAAGTGATGCTTATGGAACTTTGATTG
CTCCAAATCTGATTGGTGTAAATCACCAGCATTTCTTCAATTTCCGCCTTGACATGGATGTAGATGGAATTACAAATATG
CCAATAGAAATGAATGTAGTTTCACTTCCAGCAGGATTAGACAACCCTGCTGGCAATGCTTTTGTTATGCAAGGCATTCC
CTTAGAGGTAGAAACTGCTGCTGTTAGAGATGTTAATACATACCAGAGTCGTATGTGGATGGTTAATAGTCTGGAGAATA
AAAATCAGGTTGGTTTGCCAACAGCTTATGCCTTAATGCCTGGAGAAAATGCCTTCAATCAGTTATCTCCTTTTGCTGAA
GCGCGTCAACTTTCAGGTTTTAGCAATCATCATGCCTGGTTTACTCAGTACGATCCAGAAGAACTTTATGCTGCTGGAAA
CTATCCTAATCAGGGAGTTCCCGGTCAAGGTTTACCATCCTATATACAAGATAATGAGCTTTTGGTAGGAGAAGACGTTG
TAATGTGGTACACCATGGGAACTACTCACATGGTGCGTGCTGAAGATTGGCCAATTATGCCTGTTCATTCTATGCACTTT
AAACTCAAGCCTTGGAACTTCTTTGATGAAAACCCAGCTTTAGATATTCCCCCAAATCCAATTATTGAGTCTTGA

Upstream 100 bases:

>100_bases
TGCCATAATTTAGATTGCTATAATAAAGATAGCTATAAAGCAAGAATATCCTACTAAATCTTAATAAATCTAAAGTTTCC
TTTACTTTTTCAATTAAACT

Downstream 100 bases:

>100_bases
TTAGGTTGATAGTGCAAGTATTTTTTCTAAAAAATACTTGCGCCATAATTTTCAACATAATTTTAATACCTAATTCTCGG
ATCTATGTAAGCATTTAAAA

Product: tyramine oxidase

Products: NA

Alternate protein names: Copper amine oxidase [H]

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MELNILENNENPILLTDSFTHIDNSLIKLSQISSAESHPLDPLTAEEIEATVKIIGEQQLLSEATFFPRIALNEPAKEKV
VTHTPGTPFEREAFAVVFDSQANITYEAVVDLITGEVESWEQIPNVFVQILDPDDYDALEELTASDPEVLAALERRRINP
DNVYFTGWAPGPLSQEEAATGSRLIRGIPYVIGDDINFYGRPIEGLLVTVDLTNNQILNVSDSGNIPIAGDAGFRADEID
LREPLPPLEIVEPEGASYEFNGNQISWDKWDFRYSIDPRTGLVLHQVSYDDRSILYRGSLSELSVPYGDPDGNWRVRNAL
DVGEYSIGRFTYPMEVGRDIPENAKLLDGTFADDLGEPYLWEGAAAIYERQGGLLWSHFDFDLTEEIESRRSRELVMRSI
MTIGNYDYAVNWVFQQDGTLKVEADLTGIILAKGTEATDMETLSESDAYGTLIAPNLIGVNHQHFFNFRLDMDVDGITNM
PIEMNVVSLPAGLDNPAGNAFVMQGIPLEVETAAVRDVNTYQSRMWMVNSLENKNQVGLPTAYALMPGENAFNQLSPFAE
ARQLSGFSNHHAWFTQYDPEELYAAGNYPNQGVPGQGLPSYIQDNELLVGEDVVMWYTMGTTHMVRAEDWPIMPVHSMHF
KLKPWNFFDENPALDIPPNPIIES

Sequences:

>Translated_664_residues
MELNILENNENPILLTDSFTHIDNSLIKLSQISSAESHPLDPLTAEEIEATVKIIGEQQLLSEATFFPRIALNEPAKEKV
VTHTPGTPFEREAFAVVFDSQANITYEAVVDLITGEVESWEQIPNVFVQILDPDDYDALEELTASDPEVLAALERRRINP
DNVYFTGWAPGPLSQEEAATGSRLIRGIPYVIGDDINFYGRPIEGLLVTVDLTNNQILNVSDSGNIPIAGDAGFRADEID
LREPLPPLEIVEPEGASYEFNGNQISWDKWDFRYSIDPRTGLVLHQVSYDDRSILYRGSLSELSVPYGDPDGNWRVRNAL
DVGEYSIGRFTYPMEVGRDIPENAKLLDGTFADDLGEPYLWEGAAAIYERQGGLLWSHFDFDLTEEIESRRSRELVMRSI
MTIGNYDYAVNWVFQQDGTLKVEADLTGIILAKGTEATDMETLSESDAYGTLIAPNLIGVNHQHFFNFRLDMDVDGITNM
PIEMNVVSLPAGLDNPAGNAFVMQGIPLEVETAAVRDVNTYQSRMWMVNSLENKNQVGLPTAYALMPGENAFNQLSPFAE
ARQLSGFSNHHAWFTQYDPEELYAAGNYPNQGVPGQGLPSYIQDNELLVGEDVVMWYTMGTTHMVRAEDWPIMPVHSMHF
KLKPWNFFDENPALDIPPNPIIES
>Mature_664_residues
MELNILENNENPILLTDSFTHIDNSLIKLSQISSAESHPLDPLTAEEIEATVKIIGEQQLLSEATFFPRIALNEPAKEKV
VTHTPGTPFEREAFAVVFDSQANITYEAVVDLITGEVESWEQIPNVFVQILDPDDYDALEELTASDPEVLAALERRRINP
DNVYFTGWAPGPLSQEEAATGSRLIRGIPYVIGDDINFYGRPIEGLLVTVDLTNNQILNVSDSGNIPIAGDAGFRADEID
LREPLPPLEIVEPEGASYEFNGNQISWDKWDFRYSIDPRTGLVLHQVSYDDRSILYRGSLSELSVPYGDPDGNWRVRNAL
DVGEYSIGRFTYPMEVGRDIPENAKLLDGTFADDLGEPYLWEGAAAIYERQGGLLWSHFDFDLTEEIESRRSRELVMRSI
MTIGNYDYAVNWVFQQDGTLKVEADLTGIILAKGTEATDMETLSESDAYGTLIAPNLIGVNHQHFFNFRLDMDVDGITNM
PIEMNVVSLPAGLDNPAGNAFVMQGIPLEVETAAVRDVNTYQSRMWMVNSLENKNQVGLPTAYALMPGENAFNQLSPFAE
ARQLSGFSNHHAWFTQYDPEELYAAGNYPNQGVPGQGLPSYIQDNELLVGEDVVMWYTMGTTHMVRAEDWPIMPVHSMHF
KLKPWNFFDENPALDIPPNPIIES

Specific function: Oxidizes histamine. Other amines including phenethylamine, tyramine, tryptamine, putrescine, and benzylamine also serve as substrate [H]

COG id: COG3733

COG function: function code Q; Cu2+-containing amine oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the copper/topaquinone oxidase family [H]

Homologues:

Organism=Homo sapiens, GI60498982, Length=422, Percent_Identity=27.4881516587678, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI60498984, Length=426, Percent_Identity=26.2910798122066, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI73486661, Length=421, Percent_Identity=25.6532066508314, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4502119, Length=420, Percent_Identity=25.4761904761905, Blast_Score=119, Evalue=9e-27,
Organism=Escherichia coli, GI1787651, Length=671, Percent_Identity=34.1281669150522, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000269
- InterPro:   IPR015798
- InterPro:   IPR016182
- InterPro:   IPR015800
- InterPro:   IPR015801
- InterPro:   IPR015802 [H]

Pfam domain/function: PF01179 Cu_amine_oxid; PF02727 Cu_amine_oxidN2; PF02728 Cu_amine_oxidN3 [H]

EC number: =1.4.3.22 [H]

Molecular weight: Translated: 74299; Mature: 74299

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: PS01164 COPPER_AMINE_OXID_1 ; PS01165 COPPER_AMINE_OXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELNILENNENPILLTDSFTHIDNSLIKLSQISSAESHPLDPLTAEEIEATVKIIGEQQL
CEEEEEECCCCCEEEECCHHHHCCHHEEEHHHCCCCCCCCCCCCHHHHHHHHHHHCHHHH
LSEATFFPRIALNEPAKEKVVTHTPGTPFEREAFAVVFDSQANITYEAVVDLITGEVESW
HHHHHHCCEEECCCCHHHCEEECCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHCCHHHH
EQIPNVFVQILDPDDYDALEELTASDPEVLAALERRRINPDNVYFTGWAPGPLSQEEAAT
HHHHHHEEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
GSRLIRGIPYVIGDDINFYGRPIEGLLVTVDLTNNQILNVSDSGNIPIAGDAGFRADEID
HHHHHHCCCEEECCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCEEEECCCCCCCCCCC
LREPLPPLEIVEPEGASYEFNGNQISWDKWDFRYSIDPRTGLVLHQVSYDDRSILYRGSL
CCCCCCCCEEECCCCCEEEECCCEEECCCCEEEEEECCCCCEEEEEECCCCCEEEEECCH
SELSVPYGDPDGNWRVRNALDVGEYSIGRFTYPMEVGRDIPENAKLLDGTFADDLGEPYL
HHCCCCCCCCCCCEEEEEEECCCCCCCCEEECCHHHCCCCCCCCEEECCCHHHHCCCCEE
WEGAAAIYERQGGLLWSHFDFDLTEEIESRRSRELVMRSIMTIGNYDYAVNWVFQQDGTL
ECCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCE
KVEADLTGIILAKGTEATDMETLSESDAYGTLIAPNLIGVNHQHFFNFRLDMDVDGITNM
EEEECCEEEEEECCCCCCCHHHHCCCCCCCEEECCCEECCCCCEEEEEEEEECCCCCCCC
PIEMNVVSLPAGLDNPAGNAFVMQGIPLEVETAAVRDVNTYQSRMWMVNSLENKNQVGLP
CEEEEEEECCCCCCCCCCCEEEEECCCEEEEHHHHHCCHHHHHHEEEECCCCCCCCCCCC
TAYALMPGENAFNQLSPFAEARQLSGFSNHHAWFTQYDPEELYAAGNYPNQGVPGQGLPS
EEEEECCCCHHHHHHCHHHHHHHHCCCCCCCCEEEECCHHHHEEECCCCCCCCCCCCCCH
YIQDNELLVGEDVVMWYTMGTTHMVRAEDWPIMPVHSMHFKLKPWNFFDENPALDIPPNP
HHCCCCEEEECCEEEEEEECCEEEEECCCCCCCCEECCEEEECCCCCCCCCCCCCCCCCC
IIES
CCCC
>Mature Secondary Structure
MELNILENNENPILLTDSFTHIDNSLIKLSQISSAESHPLDPLTAEEIEATVKIIGEQQL
CEEEEEECCCCCEEEECCHHHHCCHHEEEHHHCCCCCCCCCCCCHHHHHHHHHHHCHHHH
LSEATFFPRIALNEPAKEKVVTHTPGTPFEREAFAVVFDSQANITYEAVVDLITGEVESW
HHHHHHCCEEECCCCHHHCEEECCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHCCHHHH
EQIPNVFVQILDPDDYDALEELTASDPEVLAALERRRINPDNVYFTGWAPGPLSQEEAAT
HHHHHHEEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
GSRLIRGIPYVIGDDINFYGRPIEGLLVTVDLTNNQILNVSDSGNIPIAGDAGFRADEID
HHHHHHCCCEEECCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCEEEECCCCCCCCCCC
LREPLPPLEIVEPEGASYEFNGNQISWDKWDFRYSIDPRTGLVLHQVSYDDRSILYRGSL
CCCCCCCCEEECCCCCEEEECCCEEECCCCEEEEEECCCCCEEEEEECCCCCEEEEECCH
SELSVPYGDPDGNWRVRNALDVGEYSIGRFTYPMEVGRDIPENAKLLDGTFADDLGEPYL
HHCCCCCCCCCCCEEEEEEECCCCCCCCEEECCHHHCCCCCCCCEEECCCHHHHCCCCEE
WEGAAAIYERQGGLLWSHFDFDLTEEIESRRSRELVMRSIMTIGNYDYAVNWVFQQDGTL
ECCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCE
KVEADLTGIILAKGTEATDMETLSESDAYGTLIAPNLIGVNHQHFFNFRLDMDVDGITNM
EEEECCEEEEEECCCCCCCHHHHCCCCCCCEEECCCEECCCCCEEEEEEEEECCCCCCCC
PIEMNVVSLPAGLDNPAGNAFVMQGIPLEVETAAVRDVNTYQSRMWMVNSLENKNQVGLP
CEEEEEEECCCCCCCCCCCEEEEECCCEEEEHHHHHCCHHHHHHEEEECCCCCCCCCCCC
TAYALMPGENAFNQLSPFAEARQLSGFSNHHAWFTQYDPEELYAAGNYPNQGVPGQGLPS
EEEEECCCCHHHHHHCHHHHHHHHCCCCCCCCEEEECCHHHHEEECCCCCCCCCCCCCCH
YIQDNELLVGEDVVMWYTMGTTHMVRAEDWPIMPVHSMHFKLKPWNFFDENPALDIPPNP
HHCCCCEEEECCEEEEEEECCEEEEECCCCCCCCEECCEEEECCCCCCCCCCCCCCCCCC
IIES
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7876243 [H]