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The map label for this gene is argB

Identifier: 113474927

GI number: 113474927

Start: 1811884

End: 1812762

Strand: Direct

Name: argB

Synonym: Tery_1153

Alternate gene names: 113474927

Gene position: 1811884-1812762 (Clockwise)

Preceding gene: 113474926

Following gene: 113474939

Centisome position: 23.38

GC content: 38.23

Gene sequence:

>879_bases
ATGCTAAAAAGTACAGACTTGAAAAATGAGTCAGAAATGAGCCGAGTCAAAGTGTTAAGTGAAGCACTACCTTACATTCA
AAAATTTACTGGTCGTAAGATAGTTGTGAAATATGGTGGTGCGGCTATGAGGGATAGTAATGTAAAAGATCAAGTAATGA
GAGATATTGTATTATTGTCTTGTGTCGGTATACGTCCCATTGTTGTTCACGGTGGCGGTCCAGAAATTAACTCTTGGTTG
GGTAAATTAGGAATTGAACCCCAGTTTAAGGATGGTTTGCGGGTTACTGATGCCTCTACAATGGAAGTAGTTGAGATGGT
ATTAGTGGGAAAAGTTAATAAAGAAATTGTTTCTTTAATTAATCAAGCAGGAGGATGTGCGGTAGGTTTATGTGGTAAAG
ATGCCAGCTTAATTCAAGCACGTCCAGAAGGTATAGAAGGAATTGGTTTTGTTGGGGAAGTCAGCAATGTTAAGATAGAT
ATTTTACAATCTCTAGTTGATAATGGCTATATTCCAGTAGTATCTAGTGTAGCAACTGACGAACAAGGACAAGCTTACAA
TCTTAATGCTGATACAGTGGCGGGTGAAATTGCTGCTGCTATGGAAGCAGAAAAGCTGATTCTACTTACAGATACAGCCG
GAATTTTAGAAGATTATCATAATCCAGATAGTTTAATTGTTAAGTTGGATATCCAAGAAGCAAGAGAGTTGATTGAAAAA
GGAATTGTATCCGGTGGTATGATTCCTAAAGTAAATTGTTGTGTCAGGAGTTTAGCTCAAGGAGTTCGAGCAGCTCATAT
TCTTGATGGTCGAGTTCCCCATGTACTTTTGCAGGAAATCTTGACAGATACTGGGGTTGGTTCAATGATAGTAGCTTAG

Upstream 100 bases:

>100_bases
CAGGTGCACGAGAACATAAAAATCGGGTATCATCCAGGTGAGTAAATTCCACGTTTTGCACTAGTGGGTATCCTGAGAAT
ATTTTAAATACCAACTATAT

Downstream 100 bases:

>100_bases
GATGATTTTGAGATCTAGGTCTTGGCATAGGTCAAAAGTAGAAGTTTAAAAGTCTAAAATAATATTCGACTAAATTTGTT
GGCATAAATATTCAGCACAC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLKSTDLKNESEMSRVKVLSEALPYIQKFTGRKIVVKYGGAAMRDSNVKDQVMRDIVLLSCVGIRPIVVHGGGPEINSWL
GKLGIEPQFKDGLRVTDASTMEVVEMVLVGKVNKEIVSLINQAGGCAVGLCGKDASLIQARPEGIEGIGFVGEVSNVKID
ILQSLVDNGYIPVVSSVATDEQGQAYNLNADTVAGEIAAAMEAEKLILLTDTAGILEDYHNPDSLIVKLDIQEARELIEK
GIVSGGMIPKVNCCVRSLAQGVRAAHILDGRVPHVLLQEILTDTGVGSMIVA

Sequences:

>Translated_292_residues
MLKSTDLKNESEMSRVKVLSEALPYIQKFTGRKIVVKYGGAAMRDSNVKDQVMRDIVLLSCVGIRPIVVHGGGPEINSWL
GKLGIEPQFKDGLRVTDASTMEVVEMVLVGKVNKEIVSLINQAGGCAVGLCGKDASLIQARPEGIEGIGFVGEVSNVKID
ILQSLVDNGYIPVVSSVATDEQGQAYNLNADTVAGEIAAAMEAEKLILLTDTAGILEDYHNPDSLIVKLDIQEARELIEK
GIVSGGMIPKVNCCVRSLAQGVRAAHILDGRVPHVLLQEILTDTGVGSMIVA
>Mature_292_residues
MLKSTDLKNESEMSRVKVLSEALPYIQKFTGRKIVVKYGGAAMRDSNVKDQVMRDIVLLSCVGIRPIVVHGGGPEINSWL
GKLGIEPQFKDGLRVTDASTMEVVEMVLVGKVNKEIVSLINQAGGCAVGLCGKDASLIQARPEGIEGIGFVGEVSNVKID
ILQSLVDNGYIPVVSSVATDEQGQAYNLNADTVAGEIAAAMEAEKLILLTDTAGILEDYHNPDSLIVKLDIQEARELIEK
GIVSGGMIPKVNCCVRSLAQGVRAAHILDGRVPHVLLQEILTDTGVGSMIVA

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=297, Percent_Identity=26.9360269360269, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI145693208, Length=236, Percent_Identity=33.0508474576271, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320913, Length=282, Percent_Identity=28.7234042553192, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_TRIEI (Q116Q9)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720988.1
- ProteinModelPortal:   Q116Q9
- SMR:   Q116Q9
- STRING:   Q116Q9
- GeneID:   4245736
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_1153
- NMPDR:   fig|203124.1.peg.3471
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q116Q9
- ProtClustDB:   PRK00942
- BioCyc:   TERY203124:TERY_1153-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31116; Mature: 31116

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: BINDING 94-94 BINDING 187-187

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSTDLKNESEMSRVKVLSEALPYIQKFTGRKIVVKYGGAAMRDSNVKDQVMRDIVLLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
CVGIRPIVVHGGGPEINSWLGKLGIEPQFKDGLRVTDASTMEVVEMVLVGKVNKEIVSLI
HCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHH
NQAGGCAVGLCGKDASLIQARPEGIEGIGFVGEVSNVKIDILQSLVDNGYIPVVSSVATD
HHCCCEEEEECCCCCHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEHHHHCCC
EQGQAYNLNADTVAGEIAAAMEAEKLILLTDTAGILEDYHNPDSLIVKLDIQEARELIEK
CCCCEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCEEEEEEEHHHHHHHHHH
GIVSGGMIPKVNCCVRSLAQGVRAAHILDGRVPHVLLQEILTDTGVGSMIVA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure
MLKSTDLKNESEMSRVKVLSEALPYIQKFTGRKIVVKYGGAAMRDSNVKDQVMRDIVLLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
CVGIRPIVVHGGGPEINSWLGKLGIEPQFKDGLRVTDASTMEVVEMVLVGKVNKEIVSLI
HCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHH
NQAGGCAVGLCGKDASLIQARPEGIEGIGFVGEVSNVKIDILQSLVDNGYIPVVSSVATD
HHCCCEEEEECCCCCHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEHHHHCCC
EQGQAYNLNADTVAGEIAAAMEAEKLILLTDTAGILEDYHNPDSLIVKLDIQEARELIEK
CCCCEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCEEEEEEEHHHHHHHHHH
GIVSGGMIPKVNCCVRSLAQGVRAAHILDGRVPHVLLQEILTDTGVGSMIVA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA