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The map label for this gene is mpg1 [H]

Identifier: 113474917

GI number: 113474917

Start: 1801211

End: 1802377

Strand: Reverse

Name: mpg1 [H]

Synonym: Tery_1143

Alternate gene names: 113474917

Gene position: 1802377-1801211 (Counterclockwise)

Preceding gene: 113474919

Following gene: 113474915

Centisome position: 23.26

GC content: 39.59

Gene sequence:

>1167_bases
ATGAAAGCCATGATTCTGGCTGCCGGTAAAGGAACTCGTATTCGTCCAATTACTTATCGCATTCCTAAACCGATGATTCC
TATTCTGCAAAAACCAGTAATGGAATTCCTTGTAGAGTTGCTTCGTAAACATGGTTTTGACCAAATTATGGTTAACGTTA
GTCATTTAGCAAAAGAAATAGAGAACTATTTTCGCGACGGGCAAAGATTTGGGGTCAACATTGCTTATTCTTTTGAGGGG
CGAATTGAGGATGGAAACTTGATTGGGGAGGCACTAGGTTCTGCTGGTGGTATGAGGAGAATTCAAGACTTTTATCCTTA
CTTTGATGATACTTTTATAGTTCTTTGTGGTGACGCTTTGATAGATTTGGATTTGACTAAAGCACTCCAGCGGCACAAAG
AAAAAGGAGCTATGGCTACTGTAATTATGAAGTCTATTCCTCGGGAACAGGTTTCTAGCTATGGTGTTGTAGTCACAGAT
GAAACAGGACGAATTCAGTCTTTTCAGGAGAAGCCAAAAGTTGAAGAAGCTCTTAGTACCAATATTAATACTGGTATTTA
TATTTTTGAACCAGAGGTGCTTGATTGTATTCCATCTGGTGTGGAATTTGATATTGGTAGTCAGTTATTCCCTAAGTTGG
TAGAGATAGGGGCACCTTTTTATGGTGTAGCAATGGATTTTGAATGGGTGGATATTGGTAAGGTGCCGGACTACTGGCAA
GCAATTAGAGATGTGCTCATAGGAAAAGTGAAAAATGTTTCTATTCCTGGAAAGGAAGTATCTCCAGGAATTTATACTGG
TTTGAATGTAGCCGTTAACTGGGATAAGATAGATATTAAGAGACCTGTTTATATTGGGGGTATGACCAGGATTGAAGATG
GAGCCAAAATTGTTGGGCCAAGTATGATTGGTCCTAATTGCTGGATTTGCAGTGGTGCAACTGTTGATAGTAGTGTTATT
TTTGAGTATTCTCGTTTAGGTCCAGGAGTTCGCTTAGTTGATAAGTTGGTTTTTGGTCGTTATTGTGTGGATAAGACTGG
ATCATCTATTGATGTTCAAGCGGCTTCCCTTGATTGGCTAATTACTGATACTCGTCATCCTTTTCCTTCTCCTCCTCCTG
CAGAACATGAAACAATTAAGGATATTTTGCAGGAAAATGGGGGTTAG

Upstream 100 bases:

>100_bases
TCTACCTGTTGAAGTAAGGTTTTAATAGAATAAGTATGAGCTTAGAACAGAATAATAAGTATTTTAGTCTTTTTGGCATT
TTTAAGGTGGAGGAAATAAA

Downstream 100 bases:

>100_bases
TTTTTGCTAGTCCTGCTCCCTTAATAATAGATGTGGATGAACAAGGGCTAAGAAGGTAGCAAGGAGTATAGCATTACAAC
ATCGGATTGGAAATTAATTA

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKAMILAAGKGTRIRPITYRIPKPMIPILQKPVMEFLVELLRKHGFDQIMVNVSHLAKEIENYFRDGQRFGVNIAYSFEG
RIEDGNLIGEALGSAGGMRRIQDFYPYFDDTFIVLCGDALIDLDLTKALQRHKEKGAMATVIMKSIPREQVSSYGVVVTD
ETGRIQSFQEKPKVEEALSTNINTGIYIFEPEVLDCIPSGVEFDIGSQLFPKLVEIGAPFYGVAMDFEWVDIGKVPDYWQ
AIRDVLIGKVKNVSIPGKEVSPGIYTGLNVAVNWDKIDIKRPVYIGGMTRIEDGAKIVGPSMIGPNCWICSGATVDSSVI
FEYSRLGPGVRLVDKLVFGRYCVDKTGSSIDVQAASLDWLITDTRHPFPSPPPAEHETIKDILQENGG

Sequences:

>Translated_388_residues
MKAMILAAGKGTRIRPITYRIPKPMIPILQKPVMEFLVELLRKHGFDQIMVNVSHLAKEIENYFRDGQRFGVNIAYSFEG
RIEDGNLIGEALGSAGGMRRIQDFYPYFDDTFIVLCGDALIDLDLTKALQRHKEKGAMATVIMKSIPREQVSSYGVVVTD
ETGRIQSFQEKPKVEEALSTNINTGIYIFEPEVLDCIPSGVEFDIGSQLFPKLVEIGAPFYGVAMDFEWVDIGKVPDYWQ
AIRDVLIGKVKNVSIPGKEVSPGIYTGLNVAVNWDKIDIKRPVYIGGMTRIEDGAKIVGPSMIGPNCWICSGATVDSSVI
FEYSRLGPGVRLVDKLVFGRYCVDKTGSSIDVQAASLDWLITDTRHPFPSPPPAEHETIKDILQENGG
>Mature_388_residues
MKAMILAAGKGTRIRPITYRIPKPMIPILQKPVMEFLVELLRKHGFDQIMVNVSHLAKEIENYFRDGQRFGVNIAYSFEG
RIEDGNLIGEALGSAGGMRRIQDFYPYFDDTFIVLCGDALIDLDLTKALQRHKEKGAMATVIMKSIPREQVSSYGVVVTD
ETGRIQSFQEKPKVEEALSTNINTGIYIFEPEVLDCIPSGVEFDIGSQLFPKLVEIGAPFYGVAMDFEWVDIGKVPDYWQ
AIRDVLIGKVKNVSIPGKEVSPGIYTGLNVAVNWDKIDIKRPVYIGGMTRIEDGAKIVGPSMIGPNCWICSGATVDSSVI
FEYSRLGPGVRLVDKLVFGRYCVDKTGSSIDVQAASLDWLITDTRHPFPSPPPAEHETIKDILQENGG

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=365, Percent_Identity=29.041095890411, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI11761619, Length=365, Percent_Identity=29.041095890411, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI31881779, Length=201, Percent_Identity=28.3582089552239, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI45447090, Length=201, Percent_Identity=28.3582089552239, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1789837, Length=272, Percent_Identity=26.1029411764706, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788351, Length=197, Percent_Identity=27.9187817258883, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI133931050, Length=355, Percent_Identity=29.5774647887324, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17509979, Length=240, Percent_Identity=28.75, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509981, Length=229, Percent_Identity=27.9475982532751, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320148, Length=332, Percent_Identity=29.5180722891566, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21355443, Length=326, Percent_Identity=31.2883435582822, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24644084, Length=326, Percent_Identity=31.2883435582822, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24653912, Length=376, Percent_Identity=23.936170212766, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 43024; Mature: 43024

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMILAAGKGTRIRPITYRIPKPMIPILQKPVMEFLVELLRKHGFDQIMVNVSHLAKEI
CCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHH
ENYFRDGQRFGVNIAYSFEGRIEDGNLIGEALGSAGGMRRIQDFYPYFDDTFIVLCGDAL
HHHHHCCCEECEEEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEEEECCHH
IDLDLTKALQRHKEKGAMATVIMKSIPREQVSSYGVVVTDETGRIQSFQEKPKVEEALST
HHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCCEEEECCCCCHHHHHHCCHHHHHHHC
NINTGIYIFEPEVLDCIPSGVEFDIGSQLFPKLVEIGAPFYGVAMDFEWVDIGKVPDYWQ
CCCCCEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHHH
AIRDVLIGKVKNVSIPGKEVSPGIYTGLNVAVNWDKIDIKRPVYIGGMTRIEDGAKIVGP
HHHHHHHCCCCCCCCCCCCCCCCEEECCEEEEECCEEECCCCEEECCCEEECCCCEEECC
SMIGPNCWICSGATVDSSVIFEYSRLGPGVRLVDKLVFGRYCVDKTGSSIDVQAASLDWL
CCCCCCCEEECCCCCCHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEE
ITDTRHPFPSPPPAEHETIKDILQENGG
EECCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKAMILAAGKGTRIRPITYRIPKPMIPILQKPVMEFLVELLRKHGFDQIMVNVSHLAKEI
CCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHH
ENYFRDGQRFGVNIAYSFEGRIEDGNLIGEALGSAGGMRRIQDFYPYFDDTFIVLCGDAL
HHHHHCCCEECEEEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEEEECCHH
IDLDLTKALQRHKEKGAMATVIMKSIPREQVSSYGVVVTDETGRIQSFQEKPKVEEALST
HHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCCEEEECCCCCHHHHHHCCHHHHHHHC
NINTGIYIFEPEVLDCIPSGVEFDIGSQLFPKLVEIGAPFYGVAMDFEWVDIGKVPDYWQ
CCCCCEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHHH
AIRDVLIGKVKNVSIPGKEVSPGIYTGLNVAVNWDKIDIKRPVYIGGMTRIEDGAKIVGP
HHHHHHHCCCCCCCCCCCCCCCCEEECCEEEEECCEEECCCCEEECCCEEECCCCEEECC
SMIGPNCWICSGATVDSSVIFEYSRLGPGVRLVDKLVFGRYCVDKTGSSIDVQAASLDWL
CCCCCCCEEECCCCCCHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEE
ITDTRHPFPSPPPAEHETIKDILQENGG
EECCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]