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The map label for this gene is rnc2 [H]

Identifier: 113474882

GI number: 113474882

Start: 1739339

End: 1740091

Strand: Reverse

Name: rnc2 [H]

Synonym: Tery_1105

Alternate gene names: 113474882

Gene position: 1740091-1739339 (Counterclockwise)

Preceding gene: 113474883

Following gene: 113474881

Centisome position: 22.45

GC content: 38.65

Gene sequence:

>753_bases
ATGACTCAAATGTATCATTCGCGCCAAAGGCAACTTAAATCTTTAGTTGAAAAATTATCTATTTCTCAACAAGCTTTGAT
TAAATGGAATTTATTAGATTTGGCATTAACTCACTCTACAGTTTCATCAACACATAATAATGAAAAGCTAGAGTTTTTTG
GGGATGCAGTGGTACGGCTTGTGGCGGCACAACTACTGTTGGAAAATTATCCTAATTGTTCAGTAGGAGAATTTACTGCC
ATTCGTTCTATTTTAGTAAGCGATCGCTCTTTGGCACAAATTGCCGATAAGTATGGGTGGAGTCGTTATTTATTGGTATC
CAAAAGTGCAGCAGGGGATAAAGTTGGAAGAGAGCGTCGACTTGCAGATTCTTTTGAGGCTGTTTTGGGTGCTCTTTATT
TGAGTACTAATAATTTAGAGTTGATCCGCCCTTGGTTAGATTCTCATTTTGAAAGGTTAATAGCAGAAATTCGCAAGGAT
CCCGCTTGCCACAGTTATAAGGCTGCTCTCCAAGAGCTGACTCAAGGTTATTACAAAACGTTACCAAATTATCAAGCTCA
CGAAGTAAATAAGATTTATGGCGATCGCGAACGTTTCTTTGCCGAAGTTTGGTTTAAAGGCCAGAAACTTGGTGTAGGTA
AAGGACCATCTATTAAGGCCGCAGAGGAAGCGGCTGCTAAATCTGCTTTAGATTTTTTGCAGCAGTCGGGAATACAAAAT
ATTATCAAAGAGGAAAAGGATAAAAAGGAATGA

Upstream 100 bases:

>100_bases
GAAGCAGGAGGCTAGCTCCGAAGCTTGTACAATTTTTATGGGTGAGCTTGGGGAAGTTAGTCACAAAAATATAGCAGCAG
AGACTAAAAGCATCAGAATA

Downstream 100 bases:

>100_bases
AAAGGATGAGATAAGAATATTTTATTAAGAGTTGACTACATTTTCTTAAGCTCTTGAACTGCGCTACAAAGGCTGAATAA
TTAATATTTGGAAAACTTTT

Product: RNAse III

Products: NA

Alternate protein names: Ribonuclease III 2; RNase III 2 [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTQMYHSRQRQLKSLVEKLSISQQALIKWNLLDLALTHSTVSSTHNNEKLEFFGDAVVRLVAAQLLLENYPNCSVGEFTA
IRSILVSDRSLAQIADKYGWSRYLLVSKSAAGDKVGRERRLADSFEAVLGALYLSTNNLELIRPWLDSHFERLIAEIRKD
PACHSYKAALQELTQGYYKTLPNYQAHEVNKIYGDRERFFAEVWFKGQKLGVGKGPSIKAAEEAAAKSALDFLQQSGIQN
IIKEEKDKKE

Sequences:

>Translated_250_residues
MTQMYHSRQRQLKSLVEKLSISQQALIKWNLLDLALTHSTVSSTHNNEKLEFFGDAVVRLVAAQLLLENYPNCSVGEFTA
IRSILVSDRSLAQIADKYGWSRYLLVSKSAAGDKVGRERRLADSFEAVLGALYLSTNNLELIRPWLDSHFERLIAEIRKD
PACHSYKAALQELTQGYYKTLPNYQAHEVNKIYGDRERFFAEVWFKGQKLGVGKGPSIKAAEEAAAKSALDFLQQSGIQN
IIKEEKDKKE
>Mature_249_residues
TQMYHSRQRQLKSLVEKLSISQQALIKWNLLDLALTHSTVSSTHNNEKLEFFGDAVVRLVAAQLLLENYPNCSVGEFTAI
RSILVSDRSLAQIADKYGWSRYLLVSKSAAGDKVGRERRLADSFEAVLGALYLSTNNLELIRPWLDSHFERLIAEIRKDP
ACHSYKAALQELTQGYYKTLPNYQAHEVNKIYGDRERFFAEVWFKGQKLGVGKGPSIKAAEEAAAKSALDFLQQSGIQNI
IKEEKDKKE

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=210, Percent_Identity=30.952380952381, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI155030234, Length=210, Percent_Identity=30.952380952381, Blast_Score=101, Evalue=7e-22,
Organism=Escherichia coli, GI1788920, Length=172, Percent_Identity=33.1395348837209, Blast_Score=77, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17137682, Length=210, Percent_Identity=30.4761904761905, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 28325; Mature: 28193

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50137 DS_RBD ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQMYHSRQRQLKSLVEKLSISQQALIKWNLLDLALTHSTVSSTHNNEKLEFFGDAVVRL
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VAAQLLLENYPNCSVGEFTAIRSILVSDRSLAQIADKYGWSRYLLVSKSAAGDKVGRERR
HHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
LADSFEAVLGALYLSTNNLELIRPWLDSHFERLIAEIRKDPACHSYKAALQELTQGYYKT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LPNYQAHEVNKIYGDRERFFAEVWFKGQKLGVGKGPSIKAAEEAAAKSALDFLQQSGIQN
CCCCCHHHHHHHHCHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IIKEEKDKKE
HHHHHHCCCC
>Mature Secondary Structure 
TQMYHSRQRQLKSLVEKLSISQQALIKWNLLDLALTHSTVSSTHNNEKLEFFGDAVVRL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VAAQLLLENYPNCSVGEFTAIRSILVSDRSLAQIADKYGWSRYLLVSKSAAGDKVGRERR
HHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
LADSFEAVLGALYLSTNNLELIRPWLDSHFERLIAEIRKDPACHSYKAALQELTQGYYKT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LPNYQAHEVNKIYGDRERFFAEVWFKGQKLGVGKGPSIKAAEEAAAKSALDFLQQSGIQN
CCCCCHHHHHHHHCHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IIKEEKDKKE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]