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The map label for this gene is dapL [H]

Identifier: 113474811

GI number: 113474811

Start: 1596127

End: 1597305

Strand: Direct

Name: dapL [H]

Synonym: Tery_1023

Alternate gene names: 113474811

Gene position: 1596127-1597305 (Clockwise)

Preceding gene: 113474810

Following gene: 113474813

Centisome position: 20.59

GC content: 38.93

Gene sequence:

>1179_bases
ATGTATTCGATTAACCCAGCAAAAAGGGTACAAGCACTACCACCTTATGTTTTTGCCCGTTTAGATGAGTTGAAAGCTCG
TGCCCGTGAACAAGGACTAGATTTAATTGATTTGGGAATGGGGAACCCGGATGGGGCTACCCCTAAACCAGTTGTAGAGG
CTGCCATTGCTGCTTTACAAGATTCTACCAATCACGGTTATCCACCTTTTGAAGGTACTGCTAGTTTCCGCAAAGCAATT
ACTGATTGGTATTTTCGTCGTTATAGTGTAAAACTTGACCCTGATGGAGAAGCTTTGCCACTTTTGGGTTCTAAAGAAGG
CTTAACTCATTTAGCTTTGGCATATATAAATCCAGGAAATTTAGTTTTGGCACCTAATCCTGCCTATCCCGCCCATTTTC
GTGGTCCTTTAATTGCTGGTGGTAAGGTTCATAGCATTCTACTGAAACCAGAAAATGATTGGATTATCGATCTGGCAGAT
ATTCCCGATAGTGTTGCAGAGCAGGCAAAAGTTTTCTACTTTAATTATCCTAGTAATCCTACTGGTGCTACAGCTCCACG
AGAATTTTTTCAAGATATTGTTACTTTTGCGAAAAAGTATGAAATTTTGCTAGTTCACGATTTATGTTATGCTGAGTTGG
CTTTTGATGGTTATCAGCCTACCAGTTTATTACAGATTCCTGGAGGAAAAGATATTGGTGTAGAATTCCACACTATGTCA
AAAACTTATAATATGGCTGGTTGGCGAATAGGTTTTGTAGTCGGTAACTCTAACGTTATTCAAGGGTTACGTACTTTGAA
AACTAATATGGATTATGGTGTTTTTAGTGCTTTACAACTAGCAGCTAAAACTGCTTTGCAGTTACCGGATGAATATTTAT
CTCAGGTTCAAGAACGTTATCGCCAACGTCGAGATTTTCTGATTCAAGGTTTAGGCAAATTAGGTTGGAATGTACAAAAA
ACTATGGCAACTATGTATTTATGGGTTCCTTGCCCACCAGGTATAGGTTCTACTGATTTTGCTTTGTCTGTCTTACAAAA
AACTGGGGTCGTGGTCACTCCTGGAAATGCTTTTGGTAGTGGTGGTGAGGGTTATGTGAGGATTAGTTTAATTGCTGAGT
GTAAACGTTTAGATGAAGCATTAAATCGGTTTAAGAAAGCAGGTATTTATTATCAATAA

Upstream 100 bases:

>100_bases
TATTCTTATAAAAACTTACCGAACAATTGGGTCTTTTGCCTCCCCCTTCTTGGGAAAATTTTTAGTTCGTTTTAAATAAA
TCAATAAATATGTTATCACT

Downstream 100 bases:

>100_bases
ACATCGTGAGAAATCATGTAGAGATATTCCGTGAAACCTCCCTAGCAGAGTTTTACTAGCTATTAGATTTTGCTAGATGA
ATGCTTGATTCCTCCCGGAC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MYSINPAKRVQALPPYVFARLDELKARAREQGLDLIDLGMGNPDGATPKPVVEAAIAALQDSTNHGYPPFEGTASFRKAI
TDWYFRRYSVKLDPDGEALPLLGSKEGLTHLALAYINPGNLVLAPNPAYPAHFRGPLIAGGKVHSILLKPENDWIIDLAD
IPDSVAEQAKVFYFNYPSNPTGATAPREFFQDIVTFAKKYEILLVHDLCYAELAFDGYQPTSLLQIPGGKDIGVEFHTMS
KTYNMAGWRIGFVVGNSNVIQGLRTLKTNMDYGVFSALQLAAKTALQLPDEYLSQVQERYRQRRDFLIQGLGKLGWNVQK
TMATMYLWVPCPPGIGSTDFALSVLQKTGVVVTPGNAFGSGGEGYVRISLIAECKRLDEALNRFKKAGIYYQ

Sequences:

>Translated_392_residues
MYSINPAKRVQALPPYVFARLDELKARAREQGLDLIDLGMGNPDGATPKPVVEAAIAALQDSTNHGYPPFEGTASFRKAI
TDWYFRRYSVKLDPDGEALPLLGSKEGLTHLALAYINPGNLVLAPNPAYPAHFRGPLIAGGKVHSILLKPENDWIIDLAD
IPDSVAEQAKVFYFNYPSNPTGATAPREFFQDIVTFAKKYEILLVHDLCYAELAFDGYQPTSLLQIPGGKDIGVEFHTMS
KTYNMAGWRIGFVVGNSNVIQGLRTLKTNMDYGVFSALQLAAKTALQLPDEYLSQVQERYRQRRDFLIQGLGKLGWNVQK
TMATMYLWVPCPPGIGSTDFALSVLQKTGVVVTPGNAFGSGGEGYVRISLIAECKRLDEALNRFKKAGIYYQ
>Mature_392_residues
MYSINPAKRVQALPPYVFARLDELKARAREQGLDLIDLGMGNPDGATPKPVVEAAIAALQDSTNHGYPPFEGTASFRKAI
TDWYFRRYSVKLDPDGEALPLLGSKEGLTHLALAYINPGNLVLAPNPAYPAHFRGPLIAGGKVHSILLKPENDWIIDLAD
IPDSVAEQAKVFYFNYPSNPTGATAPREFFQDIVTFAKKYEILLVHDLCYAELAFDGYQPTSLLQIPGGKDIGVEFHTMS
KTYNMAGWRIGFVVGNSNVIQGLRTLKTNMDYGVFSALQLAAKTALQLPDEYLSQVQERYRQRRDFLIQGLGKLGWNVQK
TMATMYLWVPCPPGIGSTDFALSVLQKTGVVVTPGNAFGSGGEGYVRISLIAECKRLDEALNRFKKAGIYYQ

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=327, Percent_Identity=26.2996941896024, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI56713256, Length=327, Percent_Identity=26.2996941896024, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI95147551, Length=397, Percent_Identity=22.1662468513854, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI169881279, Length=397, Percent_Identity=22.1662468513854, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI169881281, Length=304, Percent_Identity=21.0526315789474, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4507369, Length=408, Percent_Identity=22.3039215686275, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=43.421052631579, Blast_Score=343, Evalue=7e-96,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=22.5974025974026, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788627, Length=387, Percent_Identity=26.3565891472868, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=423, Percent_Identity=22.6950354609929, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71994472, Length=423, Percent_Identity=22.6950354609929, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=328, Percent_Identity=24.6951219512195, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=407, Percent_Identity=23.3415233415233, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=22.107969151671, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573069, Length=420, Percent_Identity=24.047619047619, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646114, Length=420, Percent_Identity=24.047619047619, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573067, Length=420, Percent_Identity=24.047619047619, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573065, Length=420, Percent_Identity=24.047619047619, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI18859735, Length=393, Percent_Identity=21.3740458015267, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43261; Mature: 43261

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSINPAKRVQALPPYVFARLDELKARAREQGLDLIDLGMGNPDGATPKPVVEAAIAALQ
CCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
DSTNHGYPPFEGTASFRKAITDWYFRRYSVKLDPDGEALPLLGSKEGLTHLALAYINPGN
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEECCCCCCCCCCEEEEEEECCCC
LVLAPNPAYPAHFRGPLIAGGKVHSILLKPENDWIIDLADIPDSVAEQAKVFYFNYPSNP
EEECCCCCCCCCCCCCEEECCCEEEEEEECCCCCEEEECCCCHHHHCCCEEEEEECCCCC
TGATAPREFFQDIVTFAKKYEILLVHDLCYAELAFDGYQPTSLLQIPGGKDIGVEFHTMS
CCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEC
KTYNMAGWRIGFVVGNSNVIQGLRTLKTNMDYGVFSALQLAAKTALQLPDEYLSQVQERY
CEECCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RQRRDFLIQGLGKLGWNVQKTMATMYLWVPCPPGIGSTDFALSVLQKTGVVVTPGNAFGS
HHHHHHHHHHHHHHCCCHHHEEEEEEEEEECCCCCCCHHHHHHHHHHCCEEEECCCCCCC
GGEGYVRISLIAECKRLDEALNRFKKAGIYYQ
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYSINPAKRVQALPPYVFARLDELKARAREQGLDLIDLGMGNPDGATPKPVVEAAIAALQ
CCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
DSTNHGYPPFEGTASFRKAITDWYFRRYSVKLDPDGEALPLLGSKEGLTHLALAYINPGN
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEECCCCCCCCCCEEEEEEECCCC
LVLAPNPAYPAHFRGPLIAGGKVHSILLKPENDWIIDLADIPDSVAEQAKVFYFNYPSNP
EEECCCCCCCCCCCCCEEECCCEEEEEEECCCCCEEEECCCCHHHHCCCEEEEEECCCCC
TGATAPREFFQDIVTFAKKYEILLVHDLCYAELAFDGYQPTSLLQIPGGKDIGVEFHTMS
CCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEC
KTYNMAGWRIGFVVGNSNVIQGLRTLKTNMDYGVFSALQLAAKTALQLPDEYLSQVQERY
CEECCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RQRRDFLIQGLGKLGWNVQKTMATMYLWVPCPPGIGSTDFALSVLQKTGVVVTPGNAFGS
HHHHHHHHHHHHHHCCCHHHEEEEEEEEEECCCCCCCHHHHHHHHHHCCEEEECCCCCCC
GGEGYVRISLIAECKRLDEALNRFKKAGIYYQ
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA