Click here to switch to the map view.

The map label for this gene is ghrA [H]

Identifier: 113474599

GI number: 113474599

Start: 1218825

End: 1219193

Strand: Direct

Name: ghrA [H]

Synonym: Tery_0759

Alternate gene names: 113474599

Gene position: 1218825-1219193 (Clockwise)

Preceding gene: 113474598

Following gene: 113474602

Centisome position: 15.73

GC content: 38.75

Gene sequence:

>369_bases
ATGTCTCTAGGAGCAGGTGTTAATAGAATTTTAGAAGATCCACATTTACCAGATAATATCTCTATTGTGCGTTTGGTCTG
TGAAAGCAAAAGGTTGCAAATGGTAGAGTATGTGACTATGGCTGTTTTGATTTTTCAAGGGCGGTTGCTTGAATATCAAG
TATTACAGACATCACAATGTTGGAAATATTTATCTGTACAAGATGCTACTTCATTGACTGTGGGGGTTTTGGTCTTGGGG
AACTTTGGCTTGATGGTTGCCAAAAAACTAAAATTGATGGGTTTTCCTGTTCATGGCTGGAGTAGAACTCCTAAAGCATT
TGTAGGAGTGGAGTGCTTTCACGGGAAGGAACAGTTTAAGTTTTCTTAG

Upstream 100 bases:

>100_bases
TACTATTTGGGAATGATGTATCAACTTAATGAAACAGCGTTCCCGGTAGTGTTGTGTAGCAATATGGCTCTTAAACAGGT
TTCACTACTTGAAGTTAATT

Downstream 100 bases:

>100_bases
AATAATGTCAGGCGATCGCCTGTTTGTTACTAGTCACGCTACAAACTTAAGGTATTCTTTGCCATAAATTTTTTTCGGCT
TTGCCTCCAGGAGCTTATTT

Product: putative 2-hydroxyacid dehydrogenase oxidoreductase protein

Products: NA

Alternate protein names: 2-ketoacid reductase [H]

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MSLGAGVNRILEDPHLPDNISIVRLVCESKRLQMVEYVTMAVLIFQGRLLEYQVLQTSQCWKYLSVQDATSLTVGVLVLG
NFGLMVAKKLKLMGFPVHGWSRTPKAFVGVECFHGKEQFKFS

Sequences:

>Translated_122_residues
MSLGAGVNRILEDPHLPDNISIVRLVCESKRLQMVEYVTMAVLIFQGRLLEYQVLQTSQCWKYLSVQDATSLTVGVLVLG
NFGLMVAKKLKLMGFPVHGWSRTPKAFVGVECFHGKEQFKFS
>Mature_121_residues
SLGAGVNRILEDPHLPDNISIVRLVCESKRLQMVEYVTMAVLIFQGRLLEYQVLQTSQCWKYLSVQDATSLTVGVLVLGN
FGLMVAKKLKLMGFPVHGWSRTPKAFVGVECFHGKEQFKFS

Specific function: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively [H]

COG id: COG0111

COG function: function code HE; Phosphoglycerate dehydrogenase and related dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081824, Length=123, Percent_Identity=34.9593495934959, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006140
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02826 2-Hacid_dh_C [H]

EC number: =1.1.1.79; =1.1.1.81 [H]

Molecular weight: Translated: 13719; Mature: 13588

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGAGVNRILEDPHLPDNISIVRLVCESKRLQMVEYVTMAVLIFQGRLLEYQVLQTSQC
CCCCCCHHHHHCCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
WKYLSVQDATSLTVGVLVLGNFGLMVAKKLKLMGFPVHGWSRTPKAFVGVECFHGKEQFK
HHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCC
FS
CC
>Mature Secondary Structure 
SLGAGVNRILEDPHLPDNISIVRLVCESKRLQMVEYVTMAVLIFQGRLLEYQVLQTSQC
CCCCCHHHHHCCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
WKYLSVQDATSLTVGVLVLGNFGLMVAKKLKLMGFPVHGWSRTPKAFVGVECFHGKEQFK
HHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCC
FS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA