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The map label for this gene is dapA [H]

Identifier: 113474444

GI number: 113474444

Start: 944659

End: 945549

Strand: Direct

Name: dapA [H]

Synonym: Tery_0588

Alternate gene names: 113474444

Gene position: 944659-945549 (Clockwise)

Preceding gene: 113474443

Following gene: 113474445

Centisome position: 12.19

GC content: 39.17

Gene sequence:

>891_bases
GTGGTAAACTTTGGTAGTGTTCTGACTGCAATGATTACACCGTTTAATCTAGACGGTAGTGTTAACTATGAAGAAACAGA
AAAGTTATCAATATGGTTGACAGAAAATGGAACAGACTCATTAGTGGTATGTGGAACAACAGGTGAGTCTCCGAGTCTGA
CATGGGAAGAAGAATATGAGTTATTTCAAGTAGTTCAAAAAGCAGTGGGAGGAAAAGCTAAAGTTATAGCAGGTACTGGG
TCAAATTCAACAAAAGAGGCGATCACAGCTACTGAAAAAGCAGCTAAATTGGGTTTAGGAGGTTCATTACAGGTGGTACC
ATATTACAATAAACCACCACAGTCAGGACTTTATCGGCATTTTCAAGCGATCGCTCAAGCCACGCCAGATTTCCCAATCA
TAATATATAATATACCAGGGCGTACAGGTAAAAACATGGAGCCAGAAACTGTAGCTAGACTGGCGGAAATTCCAAATATT
GTCGCTATTAAAGAAGCAAGTGGCAACTTAGACCAAGTAAGTCAGATTAGAAACTTGACGGCACCAGAGTTTAAGATTTA
TTCTGGAGATGACTACCTAACTCTACCATTAATGGCTATAGGTGGCAATGGGGTTGTTAGTGTAGCTAGTCACCTGGTAG
GAAATAAACTACAGGAGATGATAGTAGCGTTTAAAACAGGTGAAGTACAGCGTGCGACAAAAATTCATTTAGAACTATTC
AATTTATCTAGAACTCTATTTGCCACAACTAATCCCATTCCTATAAAGGAAGCTATGAATATGTTGGGATGGAATGTAGG
TAAGACTCGCCTTCCATTATGCGATCCACCAGCAGAGATTACTGAAAAATTAAGGGTAGAAATGGATAAATTAGGTCTAT
TAGCCAGATAG

Upstream 100 bases:

>100_bases
TATCTGAAGCGTATTAGTCCATAGTCCATCAATAACCCGAAAAACTAAAAATACTAAGCAAAAAAAATCTAAATAATGCC
GATCAAGGAGTGGAAATAGT

Downstream 100 bases:

>100_bases
TTTCATAGACAAAAGATGATGACCATAACTAATATATTTATATTATTGATATATTTGTATTATCGAATTAACTCTGACTT
TTGAGTTTATGGTTCCAGCA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MVNFGSVLTAMITPFNLDGSVNYEETEKLSIWLTENGTDSLVVCGTTGESPSLTWEEEYELFQVVQKAVGGKAKVIAGTG
SNSTKEAITATEKAAKLGLGGSLQVVPYYNKPPQSGLYRHFQAIAQATPDFPIIIYNIPGRTGKNMEPETVARLAEIPNI
VAIKEASGNLDQVSQIRNLTAPEFKIYSGDDYLTLPLMAIGGNGVVSVASHLVGNKLQEMIVAFKTGEVQRATKIHLELF
NLSRTLFATTNPIPIKEAMNMLGWNVGKTRLPLCDPPAEITEKLRVEMDKLGLLAR

Sequences:

>Translated_296_residues
MVNFGSVLTAMITPFNLDGSVNYEETEKLSIWLTENGTDSLVVCGTTGESPSLTWEEEYELFQVVQKAVGGKAKVIAGTG
SNSTKEAITATEKAAKLGLGGSLQVVPYYNKPPQSGLYRHFQAIAQATPDFPIIIYNIPGRTGKNMEPETVARLAEIPNI
VAIKEASGNLDQVSQIRNLTAPEFKIYSGDDYLTLPLMAIGGNGVVSVASHLVGNKLQEMIVAFKTGEVQRATKIHLELF
NLSRTLFATTNPIPIKEAMNMLGWNVGKTRLPLCDPPAEITEKLRVEMDKLGLLAR
>Mature_296_residues
MVNFGSVLTAMITPFNLDGSVNYEETEKLSIWLTENGTDSLVVCGTTGESPSLTWEEEYELFQVVQKAVGGKAKVIAGTG
SNSTKEAITATEKAAKLGLGGSLQVVPYYNKPPQSGLYRHFQAIAQATPDFPIIIYNIPGRTGKNMEPETVARLAEIPNI
VAIKEASGNLDQVSQIRNLTAPEFKIYSGDDYLTLPLMAIGGNGVVSVASHLVGNKLQEMIVAFKTGEVQRATKIHLELF
NLSRTLFATTNPIPIKEAMNMLGWNVGKTRLPLCDPPAEITEKLRVEMDKLGLLAR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=297, Percent_Identity=26.2626262626263, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI13540533, Length=307, Percent_Identity=26.0586319218241, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=40.4109589041096, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1789620, Length=290, Percent_Identity=26.551724137931, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082415, Length=304, Percent_Identity=27.9605263157895, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786463, Length=283, Percent_Identity=27.9151943462898, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32140; Mature: 32140

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNFGSVLTAMITPFNLDGSVNYEETEKLSIWLTENGTDSLVVCGTTGESPSLTWEEEYE
CCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCHHHHHH
LFQVVQKAVGGKAKVIAGTGSNSTKEAITATEKAAKLGLGGSLQVVPYYNKPPQSGLYRH
HHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
FQAIAQATPDFPIIIYNIPGRTGKNMEPETVARLAEIPNIVAIKEASGNLDQVSQIRNLT
HHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCC
APEFKIYSGDDYLTLPLMAIGGNGVVSVASHLVGNKLQEMIVAFKTGEVQRATKIHLELF
CCCEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEE
NLSRTLFATTNPIPIKEAMNMLGWNVGKTRLPLCDPPAEITEKLRVEMDKLGLLAR
ECCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVNFGSVLTAMITPFNLDGSVNYEETEKLSIWLTENGTDSLVVCGTTGESPSLTWEEEYE
CCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCHHHHHH
LFQVVQKAVGGKAKVIAGTGSNSTKEAITATEKAAKLGLGGSLQVVPYYNKPPQSGLYRH
HHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
FQAIAQATPDFPIIIYNIPGRTGKNMEPETVARLAEIPNIVAIKEASGNLDQVSQIRNLT
HHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCC
APEFKIYSGDDYLTLPLMAIGGNGVVSVASHLVGNKLQEMIVAFKTGEVQRATKIHLELF
CCCEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEE
NLSRTLFATTNPIPIKEAMNMLGWNVGKTRLPLCDPPAEITEKLRVEMDKLGLLAR
ECCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA