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The map label for this gene is appB [H]

Identifier: 113474305

GI number: 113474305

Start: 683916

End: 684992

Strand: Reverse

Name: appB [H]

Synonym: Tery_0434

Alternate gene names: 113474305

Gene position: 684992-683916 (Counterclockwise)

Preceding gene: 113474306

Following gene: 113474304

Centisome position: 8.84

GC content: 31.94

Gene sequence:

>1077_bases
ATGTTGAAGGAATTATTACAAGCAATTTTGAAGAAATTATTACAGGCAATTTTAATTTTATTATTACCACAGGCAAAACA
ACTAATTGCTAGTGAAATTTTTACTTATATATTGAAGAGATTATTACAGGCAATTTTGACTTTATTTTTAGCATCTGCTC
TTTGTTTTGCTGTAATTCAATTAGCTCCAGGCAATTATTTAGATACTTTAAGTCAAAATCCCCAAATATCTCAAGAAACT
ATTCAACAACTTGAGCAACAATTTGGGTTAGATAAGTCTGCTTTAGAACAATATTTACGTTGGTTAGGAGAAATTATTAG
AAGTGGAAATTTTGGCAGAAGTTTTGTTTTTCAGCAACCAGTAGCTGATTTATTATGGGAGAGAATACCAGCTACTTTAG
TTTTATCTATTTCTTCCTTAATCATGACTTGGGCGATCGCTATTCCTCTTGGTATTATTGCTGGAGTTAATCAAAACCGT
ATTTTAGACCGTTTTTTACAATTAATTAGTTACACTGGTCAAGGTTTTCCTAGTTTTATTACTGCTCTATTATTATTATT
TTTAGCCCAAAATATTTCTCCTTTATTACCAGTTGGAGGAATGCAAAGTATTGACTATGATGACTTCTCTTTTGTGGGTA
AAATTTTAGATATGGGTTGGCATATGATTTTACCGACTATTGCTTTAAGTATTACCAGTTTTGCTGGTTTACAGAGGTTA
ATGCGGGGGCAATTATTGGATGTTTTGCGACAAAATTATATTCAAACGGCGAGAGCGAAAGGTCTTCCAGAGAATAGAGT
GATTTATGTTCATGCTTTGAGAAATGCTATTAACCCTTTAGTAACATTATTGGGATTTGAGTTTGCTTCATTGTTAAGTG
GTTCGTTTATTGCTGAATATTTCTTTAACTGGCCAGGATTAGGAAGTCTAATTTTAGAAGCGGTAAGAAACCAGGATTTA
TATTTAGTTATGGCGAGTTTAATGATGGGAGCTTTAATGTTAATTATTGGTAATTTATTGGCAGATTTATTATTGAAAGT
TGTAGACCCTCGGATTAAGTTGGAAAGTATTAAGTGA

Upstream 100 bases:

>100_bases
TTTGGTAGAAAATATTGATGTATTTTATGTTAGTTTGGTGGATAGAAAATTGAGGTATAACCAGGTAAAATAACTAATTG
CAAGTGAAATTTTTACTTAT

Downstream 100 bases:

>100_bases
TGTCGAATGAATATTTTTAGAGTTGGAAAAATGGTGATAGTTTGTGTTGACACTGATCTTTTTATGAAAATTACTATACT
GGGAAAATATAGTAATACTA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MLKELLQAILKKLLQAILILLLPQAKQLIASEIFTYILKRLLQAILTLFLASALCFAVIQLAPGNYLDTLSQNPQISQET
IQQLEQQFGLDKSALEQYLRWLGEIIRSGNFGRSFVFQQPVADLLWERIPATLVLSISSLIMTWAIAIPLGIIAGVNQNR
ILDRFLQLISYTGQGFPSFITALLLLFLAQNISPLLPVGGMQSIDYDDFSFVGKILDMGWHMILPTIALSITSFAGLQRL
MRGQLLDVLRQNYIQTARAKGLPENRVIYVHALRNAINPLVTLLGFEFASLLSGSFIAEYFFNWPGLGSLILEAVRNQDL
YLVMASLMMGALMLIIGNLLADLLLKVVDPRIKLESIK

Sequences:

>Translated_358_residues
MLKELLQAILKKLLQAILILLLPQAKQLIASEIFTYILKRLLQAILTLFLASALCFAVIQLAPGNYLDTLSQNPQISQET
IQQLEQQFGLDKSALEQYLRWLGEIIRSGNFGRSFVFQQPVADLLWERIPATLVLSISSLIMTWAIAIPLGIIAGVNQNR
ILDRFLQLISYTGQGFPSFITALLLLFLAQNISPLLPVGGMQSIDYDDFSFVGKILDMGWHMILPTIALSITSFAGLQRL
MRGQLLDVLRQNYIQTARAKGLPENRVIYVHALRNAINPLVTLLGFEFASLLSGSFIAEYFFNWPGLGSLILEAVRNQDL
YLVMASLMMGALMLIIGNLLADLLLKVVDPRIKLESIK
>Mature_358_residues
MLKELLQAILKKLLQAILILLLPQAKQLIASEIFTYILKRLLQAILTLFLASALCFAVIQLAPGNYLDTLSQNPQISQET
IQQLEQQFGLDKSALEQYLRWLGEIIRSGNFGRSFVFQQPVADLLWERIPATLVLSISSLIMTWAIAIPLGIIAGVNQNR
ILDRFLQLISYTGQGFPSFITALLLLFLAQNISPLLPVGGMQSIDYDDFSFVGKILDMGWHMILPTIALSITSFAGLQRL
MRGQLLDVLRQNYIQTARAKGLPENRVIYVHALRNAINPLVTLLGFEFASLLSGSFIAEYFFNWPGLGSLILEAVRNQDL
YLVMASLMMGALMLIIGNLLADLLLKVVDPRIKLESIK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=334, Percent_Identity=35.6287425149701, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787053, Length=325, Percent_Identity=35.0769230769231, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787497, Length=320, Percent_Identity=32.5, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789888, Length=321, Percent_Identity=31.7757009345794, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788504, Length=363, Percent_Identity=28.6501377410468, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1787550, Length=274, Percent_Identity=31.7518248175182, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=30.0911854103343, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40002; Mature: 40002

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKELLQAILKKLLQAILILLLPQAKQLIASEIFTYILKRLLQAILTLFLASALCFAVIQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPGNYLDTLSQNPQISQETIQQLEQQFGLDKSALEQYLRWLGEIIRSGNFGRSFVFQQP
HCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VADLLWERIPATLVLSISSLIMTWAIAIPLGIIAGVNQNRILDRFLQLISYTGQGFPSFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHH
TALLLLFLAQNISPLLPVGGMQSIDYDDFSFVGKILDMGWHMILPTIALSITSFAGLQRL
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRGQLLDVLRQNYIQTARAKGLPENRVIYVHALRNAINPLVTLLGFEFASLLSGSFIAEY
HHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFNWPGLGSLILEAVRNQDLYLVMASLMMGALMLIIGNLLADLLLKVVDPRIKLESIK
HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MLKELLQAILKKLLQAILILLLPQAKQLIASEIFTYILKRLLQAILTLFLASALCFAVIQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPGNYLDTLSQNPQISQETIQQLEQQFGLDKSALEQYLRWLGEIIRSGNFGRSFVFQQP
HCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VADLLWERIPATLVLSISSLIMTWAIAIPLGIIAGVNQNRILDRFLQLISYTGQGFPSFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHH
TALLLLFLAQNISPLLPVGGMQSIDYDDFSFVGKILDMGWHMILPTIALSITSFAGLQRL
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRGQLLDVLRQNYIQTARAKGLPENRVIYVHALRNAINPLVTLLGFEFASLLSGSFIAEY
HHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFNWPGLGSLILEAVRNQDLYLVMASLMMGALMLIIGNLLADLLLKVVDPRIKLESIK
HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]