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The map label for this gene is ppx [H]

Identifier: 113474131

GI number: 113474131

Start: 359583

End: 361217

Strand: Reverse

Name: ppx [H]

Synonym: Tery_0231

Alternate gene names: 113474131

Gene position: 361217-359583 (Counterclockwise)

Preceding gene: 113474134

Following gene: 113474126

Centisome position: 4.66

GC content: 37.55

Gene sequence:

>1635_bases
ATGATTACATCAGTTCCTTTAGTTAGATTTCCTGCTCCACTAGCAGGCCAAAACCCGATATTAGCAGCAATAGATATTGG
TACAAATTCGTTGCACTTGGTTGTAGTAAAAATTGATCCTAATTTGCCGACTTTTACTATTATTGACCAAGATAAAGAAA
CAGTAAGACTAGGAGAGTGCGGCACGAAAGGTAACTTAAAACCAGAAGTGATGGATAGAGCGATCGCTACTTTAGAGCGT
TTCCAACAAATTGCTAAAAGTGCTAATGCTAAACAAATCATTACAGTTGCTACTAGTGCTGTAAGAGAAGCACCTAACGG
TAAAGAATTTCTCAATAGAATAGCTGATGAGTTAAACCTATATGTTGACTTGATATCTGGTCAAGAAGAAGCACGACGAA
TTTATCTAGGGGTACTTTCAGCAATGGAATTTAATAACCAACCCCATGTTATTATTGATATTGGTGGAGGTTCCACAGAG
TTGATCTTAGGTGATAGTGATACACTGAGAACTCTAAGTAGTACAAAAGTAGGTGCAGTACGTCTGACTAAAGAATTTGT
TACCACAAATCCCGTTAGTAAGAGTGAGTTTGCCTATCTGCAAGCTTACATTAGAGGCTTATTAGAACGCCCGACCAAAA
ACATATTAGCTAATATCAAGAAAGGTGAAAAACCTCAGTTAGTCGGAACTGCTGGTACTATTGAAGCTTTAGCGACTATT
AATGCTTATGAAAAATTGGGTAATGTACCAGCTCCCCTGGGTGGTTATCAGTTTAGTTTGACAGAATTAGAGGAGTTGGT
TAATAAGTTGAGGAAGTTACCTATTTCTAAAAGACGAGAAATTCTGGGAATGTCCGAAAAGCGAGCAGAAATTATTTTGG
CGGGTGCTTTAGTGTTACACGAAGCAATGAGTTTATTAGAGATGGAGTCGGTGACTGTGTGTGAAAGCAGTTTGCGAGAG
GGGGTAATAGTTGATTGGATGTTGAATCATGGTTTGATTGAGGATCACCTTCGTTTCCAAAGTTCAATTCGCCAACGAAA
TACTCTAAAAATTGCGCAAAAATACCAGGTTAATTTGGAGTATAGCGAACGGGTTGCTTTTTGGGCGTTATATTTATTTG
ACCAAACTATGGGAGTTCTGCATAACTGGGGAAGTGAGGAACGAGAATTGTTATGGTCAGCAGCAATTTTGCATAATTGT
GGTATATATGTAAATCATTCAGAACATCATAAACATTCCTACTATTTGATCAGAAATGGGGAGTTATTGGGGTATACTCA
AATTGAAATTGAAGTTATTGCTAATTTAGCTCGTTATCACCGCAAGAGTTTATGCAAGAAAAAACACGACCATTATCAAA
TTTTACCCAAAAGATATCAAGAAATGGTGTCTCAGTTGAGTTCATTGTTACGTTTAGCGGTAGCTTTAGATAGGCGACAA
AAAGGGGCGATAGCTAATTTGACCTGTTGGTTAAACACAAAGCAACAGGAATTTCATCTCTGGTTACGGCCTGCTAACCC
TAAAGATGATTGTGCTTTAGAATTGTGGAGTTTGGAAAATAAGAAGGAGGCCTTTGAAAAAGAGTTTGGTTTAAAATTAA
TAGTAAATTTAGAATCTGCCTCGTTAGTAACTTGA

Upstream 100 bases:

>100_bases
ATAACATTTTTTAATATAAAATTTCGGATATATGTAATTGAAAATACATTGTATCAGTAATTTAAAATACGTTGTATCAG
CAATTTAAAATACGTTGTAT

Downstream 100 bases:

>100_bases
TTTGATAGCTGAGTGAAAGAGGAAGTTCTTGATAAAAATCACTAGGAATGTTTCTAACCTTAATTGGTAAAACGAATATC
GCGAAAACTTCTGGCAACTT

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MITSVPLVRFPAPLAGQNPILAAIDIGTNSLHLVVVKIDPNLPTFTIIDQDKETVRLGECGTKGNLKPEVMDRAIATLER
FQQIAKSANAKQIITVATSAVREAPNGKEFLNRIADELNLYVDLISGQEEARRIYLGVLSAMEFNNQPHVIIDIGGGSTE
LILGDSDTLRTLSSTKVGAVRLTKEFVTTNPVSKSEFAYLQAYIRGLLERPTKNILANIKKGEKPQLVGTAGTIEALATI
NAYEKLGNVPAPLGGYQFSLTELEELVNKLRKLPISKRREILGMSEKRAEIILAGALVLHEAMSLLEMESVTVCESSLRE
GVIVDWMLNHGLIEDHLRFQSSIRQRNTLKIAQKYQVNLEYSERVAFWALYLFDQTMGVLHNWGSEERELLWSAAILHNC
GIYVNHSEHHKHSYYLIRNGELLGYTQIEIEVIANLARYHRKSLCKKKHDHYQILPKRYQEMVSQLSSLLRLAVALDRRQ
KGAIANLTCWLNTKQQEFHLWLRPANPKDDCALELWSLENKKEAFEKEFGLKLIVNLESASLVT

Sequences:

>Translated_544_residues
MITSVPLVRFPAPLAGQNPILAAIDIGTNSLHLVVVKIDPNLPTFTIIDQDKETVRLGECGTKGNLKPEVMDRAIATLER
FQQIAKSANAKQIITVATSAVREAPNGKEFLNRIADELNLYVDLISGQEEARRIYLGVLSAMEFNNQPHVIIDIGGGSTE
LILGDSDTLRTLSSTKVGAVRLTKEFVTTNPVSKSEFAYLQAYIRGLLERPTKNILANIKKGEKPQLVGTAGTIEALATI
NAYEKLGNVPAPLGGYQFSLTELEELVNKLRKLPISKRREILGMSEKRAEIILAGALVLHEAMSLLEMESVTVCESSLRE
GVIVDWMLNHGLIEDHLRFQSSIRQRNTLKIAQKYQVNLEYSERVAFWALYLFDQTMGVLHNWGSEERELLWSAAILHNC
GIYVNHSEHHKHSYYLIRNGELLGYTQIEIEVIANLARYHRKSLCKKKHDHYQILPKRYQEMVSQLSSLLRLAVALDRRQ
KGAIANLTCWLNTKQQEFHLWLRPANPKDDCALELWSLENKKEAFEKEFGLKLIVNLESASLVT
>Mature_544_residues
MITSVPLVRFPAPLAGQNPILAAIDIGTNSLHLVVVKIDPNLPTFTIIDQDKETVRLGECGTKGNLKPEVMDRAIATLER
FQQIAKSANAKQIITVATSAVREAPNGKEFLNRIADELNLYVDLISGQEEARRIYLGVLSAMEFNNQPHVIIDIGGGSTE
LILGDSDTLRTLSSTKVGAVRLTKEFVTTNPVSKSEFAYLQAYIRGLLERPTKNILANIKKGEKPQLVGTAGTIEALATI
NAYEKLGNVPAPLGGYQFSLTELEELVNKLRKLPISKRREILGMSEKRAEIILAGALVLHEAMSLLEMESVTVCESSLRE
GVIVDWMLNHGLIEDHLRFQSSIRQRNTLKIAQKYQVNLEYSERVAFWALYLFDQTMGVLHNWGSEERELLWSAAILHNC
GIYVNHSEHHKHSYYLIRNGELLGYTQIEIEVIANLARYHRKSLCKKKHDHYQILPKRYQEMVSQLSSLLRLAVALDRRQ
KGAIANLTCWLNTKQQEFHLWLRPANPKDDCALELWSLENKKEAFEKEFGLKLIVNLESASLVT

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=536, Percent_Identity=27.6119402985075, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI48994966, Length=472, Percent_Identity=28.3898305084746, Blast_Score=162, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 61254; Mature: 61254

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSVPLVRFPAPLAGQNPILAAIDIGTNSLHLVVVKIDPNLPTFTIIDQDKETVRLGEC
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEECCCCEEEECCC
GTKGNLKPEVMDRAIATLERFQQIAKSANAKQIITVATSAVREAPNGKEFLNRIADELNL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHEE
YVDLISGQEEARRIYLGVLSAMEFNNQPHVIIDIGGGSTELILGDSDTLRTLSSTKVGAV
EEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCHHHHHHHCCCCCCE
RLTKEFVTTNPVSKSEFAYLQAYIRGLLERPTKNILANIKKGEKPQLVGTAGTIEALATI
EEEHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEECCHHHHHHHHH
NAYEKLGNVPAPLGGYQFSLTELEELVNKLRKLPISKRREILGMSEKRAEIILAGALVLH
HHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHEEEHHHHHHH
EAMSLLEMESVTVCESSLREGVIVDWMLNHGLIEDHLRFQSSIRQRNTLKIAQKYQVNLE
HHHHHHHHHHHHHHHHHHHCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECC
YSERVAFWALYLFDQTMGVLHNWGSEERELLWSAAILHNCGIYVNHSEHHKHSYYLIRNG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECC
ELLGYTQIEIEVIANLARYHRKSLCKKKHDHYQILPKRYQEMVSQLSSLLRLAVALDRRQ
CEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGAIANLTCWLNTKQQEFHLWLRPANPKDDCALELWSLENKKEAFEKEFGLKLIVNLESA
CCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCC
SLVT
CCCC
>Mature Secondary Structure
MITSVPLVRFPAPLAGQNPILAAIDIGTNSLHLVVVKIDPNLPTFTIIDQDKETVRLGEC
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEECCCCEEEECCC
GTKGNLKPEVMDRAIATLERFQQIAKSANAKQIITVATSAVREAPNGKEFLNRIADELNL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHEE
YVDLISGQEEARRIYLGVLSAMEFNNQPHVIIDIGGGSTELILGDSDTLRTLSSTKVGAV
EEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCHHHHHHHCCCCCCE
RLTKEFVTTNPVSKSEFAYLQAYIRGLLERPTKNILANIKKGEKPQLVGTAGTIEALATI
EEEHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEECCHHHHHHHHH
NAYEKLGNVPAPLGGYQFSLTELEELVNKLRKLPISKRREILGMSEKRAEIILAGALVLH
HHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHEEEHHHHHHH
EAMSLLEMESVTVCESSLREGVIVDWMLNHGLIEDHLRFQSSIRQRNTLKIAQKYQVNLE
HHHHHHHHHHHHHHHHHHHCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECC
YSERVAFWALYLFDQTMGVLHNWGSEERELLWSAAILHNCGIYVNHSEHHKHSYYLIRNG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECC
ELLGYTQIEIEVIANLARYHRKSLCKKKHDHYQILPKRYQEMVSQLSSLLRLAVALDRRQ
CEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGAIANLTCWLNTKQQEFHLWLRPANPKDDCALELWSLENKKEAFEKEFGLKLIVNLESA
CCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCC
SLVT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]