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The map label for this gene is desA [H]

Identifier: 113474049

GI number: 113474049

Start: 207806

End: 208861

Strand: Direct

Name: desA [H]

Synonym: Tery_0142

Alternate gene names: 113474049

Gene position: 207806-208861 (Clockwise)

Preceding gene: 113474048

Following gene: 113474050

Centisome position: 2.68

GC content: 37.31

Gene sequence:

>1056_bases
ATGACTGTATCAATTAAAGAATCTGCTCAGGTCAATTCTAATGGTCAAAAGCACCAACTACAGCTAAAAGATATTGTAAA
AACTTTGCCGCGAGAAGTTTTCATCAAAGATCGATGGAAAACATGGGCAATGGTGACAACCAATATATTCATGGTAATTT
TAGGTTATTGGGGACTAATAATTGCACCTTGGTTTTTATTGCCCCTACTCTGGGTTTTCACTGGCACTGCATTAACAGGG
TTTTTTGTTATTGGCCATGACTGCGGTCATCGCTCTTTTGCTAACCGTAGGTGGGTAAATGATTTAGTTGGTCATTTGGT
GTTTTTACCCTTAATTTATCCCTTTCATGGTTGGCGAATAGGCCATAATCATCACCACAAACATACTAATAAGATGGGTG
AGGACAATGCTTGGCAACCTTGGTATCCAGAAGATTATGAGGTTGCTGGTAGTTCGATGCAGTTAGTGTATAGGGTTATG
CGTGGTAGACTCTGGTGGTTAGCTTCTATTGCTCACTGGGCAGTTGTGCATTTTGATTGGAGAAAATTTGAGAAAAATAA
TAAGGAAGATGTAAAGTTTTCTGCATTGGTAGTTTTTGGGTTTAGTGCGATCGCATTTCCTTTGTTAATAGCTACAGTTG
GTATGTGGGGTTTACTCAAGTTTTGGTTCATGCCTTGGTTAGTTTACCATTTCTGGATGAGTACATTTACTATTGTTCAC
CATACAGTACCAGAAATTCCCTTTACTCCTGTCCCAGAGTGGAATGAAGCAGAGGCTCAATTATTTGGTACAGTACATTG
TGATTATCCCCGTTGGGTAGAATTTCTATGTCATGATATTAATGTACATATTCCCCATCATATCTCAACAGGAATTCCTT
CATATAATCTTAGGCAAGCACATCAATTTTTGAAGGATAAATGGGGAGATAAACTTTATGAAACTCATTTTTCTTGGTCT
TTAATGAAAAAAATAACAGATCAGTGTCATTTGTATAATCAGACTAAGTTCTATCTCAGTTTTAAAGAATATGATGCTCA
GAAAGTTTCCCAGTAA

Upstream 100 bases:

>100_bases
AGCTCAAAACCGCCAGCAAAGTTTTTGAGCTGGCGTGTTTTTTTGGAGTAATAAATTTACTACATAACTATCAAAAAAAA
ACGGGGAATTTAAACAATTT

Downstream 100 bases:

>100_bases
TTTGAACTACACTCAGCTATCAGCTTCTAAAATTGTATAACCGGGTTTGAATCTTAAATGTAGCAGTGGTATTATCTCAT
TATGGAGAAATTAATCAAAC

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(12)-desaturase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTVSIKESAQVNSNGQKHQLQLKDIVKTLPREVFIKDRWKTWAMVTTNIFMVILGYWGLIIAPWFLLPLLWVFTGTALTG
FFVIGHDCGHRSFANRRWVNDLVGHLVFLPLIYPFHGWRIGHNHHHKHTNKMGEDNAWQPWYPEDYEVAGSSMQLVYRVM
RGRLWWLASIAHWAVVHFDWRKFEKNNKEDVKFSALVVFGFSAIAFPLLIATVGMWGLLKFWFMPWLVYHFWMSTFTIVH
HTVPEIPFTPVPEWNEAEAQLFGTVHCDYPRWVEFLCHDINVHIPHHISTGIPSYNLRQAHQFLKDKWGDKLYETHFSWS
LMKKITDQCHLYNQTKFYLSFKEYDAQKVSQ

Sequences:

>Translated_351_residues
MTVSIKESAQVNSNGQKHQLQLKDIVKTLPREVFIKDRWKTWAMVTTNIFMVILGYWGLIIAPWFLLPLLWVFTGTALTG
FFVIGHDCGHRSFANRRWVNDLVGHLVFLPLIYPFHGWRIGHNHHHKHTNKMGEDNAWQPWYPEDYEVAGSSMQLVYRVM
RGRLWWLASIAHWAVVHFDWRKFEKNNKEDVKFSALVVFGFSAIAFPLLIATVGMWGLLKFWFMPWLVYHFWMSTFTIVH
HTVPEIPFTPVPEWNEAEAQLFGTVHCDYPRWVEFLCHDINVHIPHHISTGIPSYNLRQAHQFLKDKWGDKLYETHFSWS
LMKKITDQCHLYNQTKFYLSFKEYDAQKVSQ
>Mature_350_residues
TVSIKESAQVNSNGQKHQLQLKDIVKTLPREVFIKDRWKTWAMVTTNIFMVILGYWGLIIAPWFLLPLLWVFTGTALTGF
FVIGHDCGHRSFANRRWVNDLVGHLVFLPLIYPFHGWRIGHNHHHKHTNKMGEDNAWQPWYPEDYEVAGSSMQLVYRVMR
GRLWWLASIAHWAVVHFDWRKFEKNNKEDVKFSALVVFGFSAIAFPLLIATVGMWGLLKFWFMPWLVYHFWMSTFTIVHH
TVPEIPFTPVPEWNEAEAQLFGTVHCDYPRWVEFLCHDINVHIPHHISTGIPSYNLRQAHQFLKDKWGDKLYETHFSWSL
MKKITDQCHLYNQTKFYLSFKEYDAQKVSQ

Specific function: Can introduce a second cis double bond at the Delta(12) position of fatty acid bound to membranes glycerolipids. This enzyme is involved in chilling tolerance because the phase transition temperature of lipids of cellular membranes depends on the degree o

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17542730, Length=311, Percent_Identity=23.1511254019293, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71999459, Length=327, Percent_Identity=24.1590214067278, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 41619; Mature: 41487

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSIKESAQVNSNGQKHQLQLKDIVKTLPREVFIKDRWKTWAMVTTNIFMVILGYWGLI
CEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IAPWFLLPLLWVFTGTALTGFFVIGHDCGHRSFANRRWVNDLVGHLVFLPLIYPFHGWRI
HHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
GHNHHHKHTNKMGEDNAWQPWYPEDYEVAGSSMQLVYRVMRGRLWWLASIAHWAVVHFDW
CCCCCHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHH
RKFEKNNKEDVKFSALVVFGFSAIAFPLLIATVGMWGLLKFWFMPWLVYHFWMSTFTIVH
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTVPEIPFTPVPEWNEAEAQLFGTVHCDYPRWVEFLCHDINVHIPHHISTGIPSYNLRQA
HHCCCCCCCCCCCCCCCCHHEEEEEECCCHHHHHHHHHHCCEEECCHHHCCCCCCCHHHH
HQFLKDKWGDKLYETHFSWSLMKKITDQCHLYNQTKFYLSFKEYDAQKVSQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCHHHCCC
>Mature Secondary Structure 
TVSIKESAQVNSNGQKHQLQLKDIVKTLPREVFIKDRWKTWAMVTTNIFMVILGYWGLI
EEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IAPWFLLPLLWVFTGTALTGFFVIGHDCGHRSFANRRWVNDLVGHLVFLPLIYPFHGWRI
HHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
GHNHHHKHTNKMGEDNAWQPWYPEDYEVAGSSMQLVYRVMRGRLWWLASIAHWAVVHFDW
CCCCCHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHH
RKFEKNNKEDVKFSALVVFGFSAIAFPLLIATVGMWGLLKFWFMPWLVYHFWMSTFTIVH
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTVPEIPFTPVPEWNEAEAQLFGTVHCDYPRWVEFLCHDINVHIPHHISTGIPSYNLRQA
HHCCCCCCCCCCCCCCCCHHEEEEEECCCHHHHHHHHHHCCEEECCHHHCCCCCCCHHHH
HQFLKDKWGDKLYETHFSWSLMKKITDQCHLYNQTKFYLSFKEYDAQKVSQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA