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The map label for this gene is bcd [H]

Identifier: 110835600

GI number: 110835600

Start: 3096995

End: 3098809

Strand: Direct

Name: bcd [H]

Synonym: ABO_2739

Alternate gene names: 110835600

Gene position: 3096995-3098809 (Clockwise)

Preceding gene: 110835599

Following gene: 110835601

Centisome position: 99.26

GC content: 54.16

Gene sequence:

>1815_bases
ATGCCAACCTACAAGGCTCCCGTGCGCGATATGCGCTTTTTGATGAACGAAGTGTTCGATTTTGAGCGTCACTACAAGGC
TCAGCCCAATGGTGAAGAAGCCACCCCCGATATGGTGGAAGCCATTATCGGTGAAATGGCCAAATTATGTGAAAACACTA
TTGCGCCCCTTTACCAGAGCGGTGACGAGGAAGGCTGTAAACTGGAAGATGGCGTGGTGACCACCCCGAAGGGTTTCAAA
GAAGCCTACGACGAATTCATCGCTGGCGGCTGGCAAGGTCTGAGCCACCCGGTAGAAGTGGGCGGCCAAGGCCTGCCCAT
GTCTCTGGGCCTGATTAAACAGGAAATGATGGCCACGGCTAACTGGTCCTTTTCCATGTACCCGGGGCTATCTCTGGGTG
CCATGAACACTATCCAGATGCACGGTTCCGAAGAACAGAAACAGGATTACCTGGTACCGCTCACCGAAGGCACCTGGGGC
GGCACCATGTGCCTAACTGAACCTCAGTGCGGCACCGACCTGGGCCAGGTAAAAACCAAAGCCGACCCGCAGCAAGACGG
TTCTTACAAAATCTCCGGTACCAAGATTTTCATTTCCTCCGGTGATCATGACCTAACCGAAAACATTATCCACATCGTGT
TGGCCCGCCTACCCGATGCACCGAAAGGTACTAAGGGAATTTCCCTGTTCATCGTACCCAAGTACTTGCCCGGCAAAATC
GGTGAACACAACGGCGTAAGCTGTGGTTCCCTGGAAAAGAAAATGGGCATCAAGGCATCCGCCACCTGCGTGATTAATTT
TGATGAAGCCACCGGCTTTTTGATCGGCCCGGAACACGGCGGCCTGGAGTGCATGTTCACCTTCATGAACAGCGCCCGTA
TCGGTACGGCAATGCAAGGTGTGGCCCATGCAGAACGGTCTTATCAAGGGGCACTACCTTACGCCAAAGAGCGCAAGTCC
ATGCGCGCACTGTCCGGCAAGAAAGAGCCCGATGCCATCGCTGACAGCTTGATTCATCACGGCGACGTACGCCGCATGCT
ACTCAAGCAAAAGGCTATTGCCGAAGGCGGCCGCGCGATGATTTATTACGCTGCCCAGTACGCAGACAACATGATCGCTG
GCATGCTCGAAGACGACATGGAAAAATACGACCACTGGGATAGCGAGCTGGGTTTCCTTACGCCGATCCTGAAAGGCTTC
CTCACTGAAAAAGGCCTGGAAGCGGCCAACGAAGGCATGCAAGTTTTCGGTGGCCACGGTTACATTAAAGAACACGGTAT
GGAACAGATCGCTCGCGATGCGCGCATCTCAACTCTGTACGAAGGCACCACCGGTATCCAGGCGCTGGACTTACTTGGCC
GCAAGGTACTGCTGTCTTCCCGCGGCAAGTGTGTGCGTGAATTCTCCAAAAAACTGGTGGATTTCGGCACCAAGAACCTA
CGTGATCCCAAGCTGCGTCCGTTCGCCTGGAAGCTGCTGAAAATTGCTGCCGAGTGGAACTACCTAACCACACGCATCAT
GCTGGTGGCCGCAAAGGATCGCGATATGGTGGCCACTGCCAGCTACGACTTCTTGATGTACAGCGGTTACGCCATGATGG
CTTACTTCTGGGCGCTGCAAGCCGGTGTTGCCACTGACAAGCTGGAAAATGGCGGCAAAGAGCCGGCAGAATTCTACAAA
GCCAAATTGGCTACCGCAGAATTTTATTTCGACCGCATGCTGCCCAGCGCCAAGGGCCATGCCGAAGCGGCTCTCAAGCC
CACCAAAAGCACCATGCAGTTGAGCGCTGAGCACTTTTCGTTCGATTACGAATAA

Upstream 100 bases:

>100_bases
CCTTGGCAGTCAATGCCTTCATCCTTGAATTGCCCAACAATGCCTGCCCTGTTGCGCTGTCCGTTCCTGACAGTTAATCC
GTTTTCTTAGGGTGATTGCT

Downstream 100 bases:

>100_bases
CACCTTGCGTTCAATAATAAGGCGGCCACTTGGCCGCCTTATTATTTTTTATCTATCCGCACCCCAACCAGGCCTGGTTA
TCCAGGCACCCTCCTTTTAT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 604; Mature: 603

Protein sequence:

>604_residues
MPTYKAPVRDMRFLMNEVFDFERHYKAQPNGEEATPDMVEAIIGEMAKLCENTIAPLYQSGDEEGCKLEDGVVTTPKGFK
EAYDEFIAGGWQGLSHPVEVGGQGLPMSLGLIKQEMMATANWSFSMYPGLSLGAMNTIQMHGSEEQKQDYLVPLTEGTWG
GTMCLTEPQCGTDLGQVKTKADPQQDGSYKISGTKIFISSGDHDLTENIIHIVLARLPDAPKGTKGISLFIVPKYLPGKI
GEHNGVSCGSLEKKMGIKASATCVINFDEATGFLIGPEHGGLECMFTFMNSARIGTAMQGVAHAERSYQGALPYAKERKS
MRALSGKKEPDAIADSLIHHGDVRRMLLKQKAIAEGGRAMIYYAAQYADNMIAGMLEDDMEKYDHWDSELGFLTPILKGF
LTEKGLEAANEGMQVFGGHGYIKEHGMEQIARDARISTLYEGTTGIQALDLLGRKVLLSSRGKCVREFSKKLVDFGTKNL
RDPKLRPFAWKLLKIAAEWNYLTTRIMLVAAKDRDMVATASYDFLMYSGYAMMAYFWALQAGVATDKLENGGKEPAEFYK
AKLATAEFYFDRMLPSAKGHAEAALKPTKSTMQLSAEHFSFDYE

Sequences:

>Translated_604_residues
MPTYKAPVRDMRFLMNEVFDFERHYKAQPNGEEATPDMVEAIIGEMAKLCENTIAPLYQSGDEEGCKLEDGVVTTPKGFK
EAYDEFIAGGWQGLSHPVEVGGQGLPMSLGLIKQEMMATANWSFSMYPGLSLGAMNTIQMHGSEEQKQDYLVPLTEGTWG
GTMCLTEPQCGTDLGQVKTKADPQQDGSYKISGTKIFISSGDHDLTENIIHIVLARLPDAPKGTKGISLFIVPKYLPGKI
GEHNGVSCGSLEKKMGIKASATCVINFDEATGFLIGPEHGGLECMFTFMNSARIGTAMQGVAHAERSYQGALPYAKERKS
MRALSGKKEPDAIADSLIHHGDVRRMLLKQKAIAEGGRAMIYYAAQYADNMIAGMLEDDMEKYDHWDSELGFLTPILKGF
LTEKGLEAANEGMQVFGGHGYIKEHGMEQIARDARISTLYEGTTGIQALDLLGRKVLLSSRGKCVREFSKKLVDFGTKNL
RDPKLRPFAWKLLKIAAEWNYLTTRIMLVAAKDRDMVATASYDFLMYSGYAMMAYFWALQAGVATDKLENGGKEPAEFYK
AKLATAEFYFDRMLPSAKGHAEAALKPTKSTMQLSAEHFSFDYE
>Mature_603_residues
PTYKAPVRDMRFLMNEVFDFERHYKAQPNGEEATPDMVEAIIGEMAKLCENTIAPLYQSGDEEGCKLEDGVVTTPKGFKE
AYDEFIAGGWQGLSHPVEVGGQGLPMSLGLIKQEMMATANWSFSMYPGLSLGAMNTIQMHGSEEQKQDYLVPLTEGTWGG
TMCLTEPQCGTDLGQVKTKADPQQDGSYKISGTKIFISSGDHDLTENIIHIVLARLPDAPKGTKGISLFIVPKYLPGKIG
EHNGVSCGSLEKKMGIKASATCVINFDEATGFLIGPEHGGLECMFTFMNSARIGTAMQGVAHAERSYQGALPYAKERKSM
RALSGKKEPDAIADSLIHHGDVRRMLLKQKAIAEGGRAMIYYAAQYADNMIAGMLEDDMEKYDHWDSELGFLTPILKGFL
TEKGLEAANEGMQVFGGHGYIKEHGMEQIARDARISTLYEGTTGIQALDLLGRKVLLSSRGKCVREFSKKLVDFGTKNLR
DPKLRPFAWKLLKIAAEWNYLTTRIMLVAAKDRDMVATASYDFLMYSGYAMMAYFWALQAGVATDKLENGGKEPAEFYKA
KLATAEFYFDRMLPSAKGHAEAALKPTKSTMQLSAEHFSFDYE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=419, Percent_Identity=28.6396181384248, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI4557235, Length=389, Percent_Identity=28.5347043701799, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI76496475, Length=389, Percent_Identity=28.5347043701799, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=28.7634408602151, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI187960098, Length=364, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI4557231, Length=364, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI4501857, Length=386, Percent_Identity=26.9430051813472, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI226958412, Length=418, Percent_Identity=25.1196172248804, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI21361497, Length=377, Percent_Identity=25.9946949602122, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=26.8817204301075, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI226958414, Length=374, Percent_Identity=25.668449197861, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI87082384, Length=290, Percent_Identity=27.2413793103448, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786223, Length=335, Percent_Identity=25.9701492537313, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17508101, Length=413, Percent_Identity=27.1186440677966, Blast_Score=125, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17569725, Length=338, Percent_Identity=29.2899408284024, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17506239, Length=364, Percent_Identity=26.3736263736264, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=28.2722513089005, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=334, Percent_Identity=29.940119760479, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI86563383, Length=337, Percent_Identity=25.8160237388724, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI86563381, Length=337, Percent_Identity=26.4094955489614, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17533517, Length=367, Percent_Identity=26.7029972752044, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=372, Percent_Identity=25.2688172043011, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=367, Percent_Identity=25.8855585831063, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=329, Percent_Identity=27.0516717325228, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=245, Percent_Identity=27.3469387755102, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=28.8793103448276, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=356, Percent_Identity=22.1910112359551, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666513, Length=427, Percent_Identity=26.9320843091335, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646207, Length=354, Percent_Identity=28.8135593220339, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281363737, Length=332, Percent_Identity=27.1084337349398, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355753, Length=389, Percent_Identity=25.4498714652956, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920834, Length=360, Percent_Identity=28.0555555555556, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 66649; Mature: 66518

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTYKAPVRDMRFLMNEVFDFERHYKAQPNGEEATPDMVEAIIGEMAKLCENTIAPLYQS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GDEEGCKLEDGVVTTPKGFKEAYDEFIAGGWQGLSHPVEVGGQGLPMSLGLIKQEMMATA
CCCCCCEECCCEEECCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHC
NWSFSMYPGLSLGAMNTIQMHGSEEQKQDYLVPLTEGTWGGTMCLTEPQCGTDLGQVKTK
CCCEEECCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCHHHHCCC
ADPQQDGSYKISGTKIFISSGDHDLTENIIHIVLARLPDAPKGTKGISLFIVPKYLPGKI
CCCCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
GEHNGVSCGSLEKKMGIKASATCVINFDEATGFLIGPEHGGLECMFTFMNSARIGTAMQG
CCCCCCCCCCHHHHCCCCEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHCHHHHHHHHH
VAHAERSYQGALPYAKERKSMRALSGKKEPDAIADSLIHHGDVRRMLLKQKAIAEGGRAM
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IYYAAQYADNMIAGMLEDDMEKYDHWDSELGFLTPILKGFLTEKGLEAANEGMQVFGGHG
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
YIKEHGMEQIARDARISTLYEGTTGIQALDLLGRKVLLSSRGKCVREFSKKLVDFGTKNL
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
RDPKLRPFAWKLLKIAAEWNYLTTRIMLVAAKDRDMVATASYDFLMYSGYAMMAYFWALQ
CCCCCCHHHHHHHHHHHHCHHEEEEEEEEEECCCCEEEECCCCHHHHCCHHHHHHHHHHH
AGVATDKLENGGKEPAEFYKAKLATAEFYFDRMLPSAKGHAEAALKPTKSTMQLSAEHFS
HCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCC
FDYE
CCCC
>Mature Secondary Structure 
PTYKAPVRDMRFLMNEVFDFERHYKAQPNGEEATPDMVEAIIGEMAKLCENTIAPLYQS
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GDEEGCKLEDGVVTTPKGFKEAYDEFIAGGWQGLSHPVEVGGQGLPMSLGLIKQEMMATA
CCCCCCEECCCEEECCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHC
NWSFSMYPGLSLGAMNTIQMHGSEEQKQDYLVPLTEGTWGGTMCLTEPQCGTDLGQVKTK
CCCEEECCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCHHHHCCC
ADPQQDGSYKISGTKIFISSGDHDLTENIIHIVLARLPDAPKGTKGISLFIVPKYLPGKI
CCCCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
GEHNGVSCGSLEKKMGIKASATCVINFDEATGFLIGPEHGGLECMFTFMNSARIGTAMQG
CCCCCCCCCCHHHHCCCCEEEEEEEEECCCCCEEECCCCCCHHHHHHHHHCHHHHHHHHH
VAHAERSYQGALPYAKERKSMRALSGKKEPDAIADSLIHHGDVRRMLLKQKAIAEGGRAM
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IYYAAQYADNMIAGMLEDDMEKYDHWDSELGFLTPILKGFLTEKGLEAANEGMQVFGGHG
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
YIKEHGMEQIARDARISTLYEGTTGIQALDLLGRKVLLSSRGKCVREFSKKLVDFGTKNL
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
RDPKLRPFAWKLLKIAAEWNYLTTRIMLVAAKDRDMVATASYDFLMYSGYAMMAYFWALQ
CCCCCCHHHHHHHHHHHHCHHEEEEEEEEEECCCCEEEECCCCHHHHCCHHHHHHHHHHH
AGVATDKLENGGKEPAEFYKAKLATAEFYFDRMLPSAKGHAEAALKPTKSTMQLSAEHFS
HCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCC
FDYE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]