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The map label for this gene is rpiA

Identifier: 110835467

GI number: 110835467

Start: 2950277

End: 2950933

Strand: Direct

Name: rpiA

Synonym: ABO_2606

Alternate gene names: 110835467

Gene position: 2950277-2950933 (Clockwise)

Preceding gene: 110835465

Following gene: 110835470

Centisome position: 94.56

GC content: 53.27

Gene sequence:

>657_bases
ATGGATCAGGATGTGCTGAAAAAGCAGGTAGCAGAAGCCGCGCTGCGTTTCGTCCCAGAAGGGGACATCATCGGCGTGGG
CACCGGCTCCACCGCCAACTTTTTTATCGACGCACTAGCTACCCTGAAAGACCGAATCAAGGGTACCGTCGCCAGCTCGG
AGGCCACCGCCGAGCGGCTCAAGCAACACGGCATCGAAGTATTCTCACTGAATGATGTGGGCAGCCTATCGGTTTACGTC
GACGGCGCCGATGAGGTGAACCAGCACCGGGAAATGATCAAGGGCGGGGGCGGCGCGCTTACCCGCGAAAAAATTGTCGC
GGCCATGGCCAAAGAGTTCATCTGCATCGTTGATGGTTCCAAACAGGTAAACCGTCTAGGTGCCTTTCCTCTTCCTATAG
AAGTCATCCCGATGGCGCGCTCTTACGTGGCACGTAAACTAGTCGCACTAGGCGGGCAGCCGCAATATCGGGAAGGTTTT
TTGACCGATAACGGCAACATCATCCTAGATGTACATAATTTGGACATCAGCAATCCCATTGAACTAGAAACCACGCTCAA
TAATATTGTCGGCGTTGTCACCAATGGGCTATTTGCCAAACGCCCTGCAGATATTGTTCTGGTCGGCGAAAAAAGTGGTG
CCGTAAACCAATACTGA

Upstream 100 bases:

>100_bases
ACAAATGCGATAGGCTAGGGTCGAGCCACAGCCACGGCTGACCTATAATTGGCGCACACTTCACCGGCGACACATACCGA
CAAGACGACAGGATACCCAC

Downstream 100 bases:

>100_bases
AGCGATAACAGATTCATCGAAAATTTGGCTAAAAACCTCTATTGTGCCTGAGGAATCGCATCATCACTGAGAGAAGTTGA
TATCGCTGCCCGAAGGCGCC

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MDQDVLKKQVAEAALRFVPEGDIIGVGTGSTANFFIDALATLKDRIKGTVASSEATAERLKQHGIEVFSLNDVGSLSVYV
DGADEVNQHREMIKGGGGALTREKIVAAMAKEFICIVDGSKQVNRLGAFPLPIEVIPMARSYVARKLVALGGQPQYREGF
LTDNGNIILDVHNLDISNPIELETTLNNIVGVVTNGLFAKRPADIVLVGEKSGAVNQY

Sequences:

>Translated_218_residues
MDQDVLKKQVAEAALRFVPEGDIIGVGTGSTANFFIDALATLKDRIKGTVASSEATAERLKQHGIEVFSLNDVGSLSVYV
DGADEVNQHREMIKGGGGALTREKIVAAMAKEFICIVDGSKQVNRLGAFPLPIEVIPMARSYVARKLVALGGQPQYREGF
LTDNGNIILDVHNLDISNPIELETTLNNIVGVVTNGLFAKRPADIVLVGEKSGAVNQY
>Mature_218_residues
MDQDVLKKQVAEAALRFVPEGDIIGVGTGSTANFFIDALATLKDRIKGTVASSEATAERLKQHGIEVFSLNDVGSLSVYV
DGADEVNQHREMIKGGGGALTREKIVAAMAKEFICIVDGSKQVNRLGAFPLPIEVIPMARSYVARKLVALGGQPQYREGF
LTDNGNIILDVHNLDISNPIELETTLNNIVGVVTNGLFAKRPADIVLVGEKSGAVNQY

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=227, Percent_Identity=35.2422907488987, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1789280, Length=213, Percent_Identity=63.3802816901408, Blast_Score=278, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17551758, Length=211, Percent_Identity=37.4407582938389, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=197, Percent_Identity=30.9644670050761, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281364072, Length=202, Percent_Identity=35.1485148514851, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_ALCBS (Q0VL94)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_694326.1
- ProteinModelPortal:   Q0VL94
- SMR:   Q0VL94
- STRING:   Q0VL94
- GeneID:   4212174
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2606
- NMPDR:   fig|393595.12.peg.2613
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   DKSIVGV
- PhylomeDB:   Q0VL94
- BioCyc:   ABOR393595:ABO_2606-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23349; Mature: 23349

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQDVLKKQVAEAALRFVPEGDIIGVGTGSTANFFIDALATLKDRIKGTVASSEATAERL
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KQHGIEVFSLNDVGSLSVYVDGADEVNQHREMIKGGGGALTREKIVAAMAKEFICIVDGS
HHCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCC
KQVNRLGAFPLPIEVIPMARSYVARKLVALGGQPQYREGFLTDNGNIILDVHNLDISNPI
HHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEECCCCCCCE
ELETTLNNIVGVVTNGLFAKRPADIVLVGEKSGAVNQY
EHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MDQDVLKKQVAEAALRFVPEGDIIGVGTGSTANFFIDALATLKDRIKGTVASSEATAERL
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KQHGIEVFSLNDVGSLSVYVDGADEVNQHREMIKGGGGALTREKIVAAMAKEFICIVDGS
HHCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCC
KQVNRLGAFPLPIEVIPMARSYVARKLVALGGQPQYREGFLTDNGNIILDVHNLDISNPI
HHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEECCCCCCCE
ELETTLNNIVGVVTNGLFAKRPADIVLVGEKSGAVNQY
EHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA