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The map label for this gene is ilvE [H]

Identifier: 110835162

GI number: 110835162

Start: 2623272

End: 2624198

Strand: Reverse

Name: ilvE [H]

Synonym: ABO_2301

Alternate gene names: 110835162

Gene position: 2624198-2623272 (Counterclockwise)

Preceding gene: 110835163

Following gene: 110835161

Centisome position: 84.11

GC content: 57.61

Gene sequence:

>927_bases
ATGTCGATGGCTGTAAGAGACGGTTTTATCTGGTTGGATGGCGAGCTGGTTCCCTGGCAAGAGGCCAAGGTTCACGTGCT
GACGCATACCCTGCATTACGGCATGGGCGTGTTTGAAGGCGTGCGTGCCTATGAGACAGCAAAAGGGCCGGCTATTTTCC
GCCTGCAGGATCACACCGACCGGTTTTTCAACAGTGCGCATATCCTCAACATGAAGCTGCCCTATACCAAGGAGCAGATC
AACGAGGCGCATCTGTCGGCGATTCGCGAAAATAATCTGCCCCACGCCTACCTGCGCCCGATGGCGTTTTACGGCAGTGA
AGGCATGGGCCTGCGTGCCCACAACCTGAAAGTGCACGTGATGGTGGCCGCCTGGGAATGGCCGTCCTACATGTCGCCGG
AGGCGCTGGAGCTGGGCATCAAGGTGCGTACCTCCAGCTACACGCGTCACCATGTGAACATCACCATGTGCAAGGCGAAA
GCCAACGGCAACTACATGAACTCCATGCTGGCGCTGAACGAAGCCCTGTCCGGTGGCGCCGATGAAGCCTTGCTGCTGGA
TAACGAGGGTTATGTGGCAGAAGGCTCCGGTGAGAATGTGTTCCTGGTTCGCGACGGTATCATTTACACCCCGGAACTGA
CCTCTTGCCTGGATGGCATTACCCGCAAAACCATCATGCAACTGGCCGAAGAGCGTGGTTATCCGGTGCGAGAGAAGCGC
ATCACCCGTGACGAGCTCTACATTGCCGACGAAGCCTTCTTCACCGGCACCGCCGCTGAAGTGATGCCGATTCGCGAACT
GGATGGCCGTATCATCGGTGCCGGCAAGCGAGGCCCGGTGACTGAACAGCTGCAGGCGGTGTATTTCGATCTGGTGCGCG
GCAAACTGGATGACGACTACGGAGACTGGCTCACTTACGTGAGCTAA

Upstream 100 bases:

>100_bases
ATTCCGCGATTTGCGTGAAGGCGTGCGAACGATCTGGAAGCATTGGTTCGACCTGTAGGGCGTTCGCTCAAAGGTCCTTA
GTTCTGGGAGTATCACTGCC

Downstream 100 bases:

>100_bases
ACAGGCGGATGCCGGCTACCTTGACCGACTCGCCCTCCGCCATCCTTGTCGTCGGCCCGTCCTGGGTCGGCGACATGGTG
ATGGCGCAAACGCTGTTTTC

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSMAVRDGFIWLDGELVPWQEAKVHVLTHTLHYGMGVFEGVRAYETAKGPAIFRLQDHTDRFFNSAHILNMKLPYTKEQI
NEAHLSAIRENNLPHAYLRPMAFYGSEGMGLRAHNLKVHVMVAAWEWPSYMSPEALELGIKVRTSSYTRHHVNITMCKAK
ANGNYMNSMLALNEALSGGADEALLLDNEGYVAEGSGENVFLVRDGIIYTPELTSCLDGITRKTIMQLAEERGYPVREKR
ITRDELYIADEAFFTGTAAEVMPIRELDGRIIGAGKRGPVTEQLQAVYFDLVRGKLDDDYGDWLTYVS

Sequences:

>Translated_308_residues
MSMAVRDGFIWLDGELVPWQEAKVHVLTHTLHYGMGVFEGVRAYETAKGPAIFRLQDHTDRFFNSAHILNMKLPYTKEQI
NEAHLSAIRENNLPHAYLRPMAFYGSEGMGLRAHNLKVHVMVAAWEWPSYMSPEALELGIKVRTSSYTRHHVNITMCKAK
ANGNYMNSMLALNEALSGGADEALLLDNEGYVAEGSGENVFLVRDGIIYTPELTSCLDGITRKTIMQLAEERGYPVREKR
ITRDELYIADEAFFTGTAAEVMPIRELDGRIIGAGKRGPVTEQLQAVYFDLVRGKLDDDYGDWLTYVS
>Mature_307_residues
SMAVRDGFIWLDGELVPWQEAKVHVLTHTLHYGMGVFEGVRAYETAKGPAIFRLQDHTDRFFNSAHILNMKLPYTKEQIN
EAHLSAIRENNLPHAYLRPMAFYGSEGMGLRAHNLKVHVMVAAWEWPSYMSPEALELGIKVRTSSYTRHHVNITMCKAKA
NGNYMNSMLALNEALSGGADEALLLDNEGYVAEGSGENVFLVRDGIIYTPELTSCLDGITRKTIMQLAEERGYPVREKRI
TRDELYIADEAFFTGTAAEVMPIRELDGRIIGAGKRGPVTEQLQAVYFDLVRGKLDDDYGDWLTYVS

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=302, Percent_Identity=45.0331125827815, Blast_Score=280, Evalue=7e-77,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34697; Mature: 34566

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMAVRDGFIWLDGELVPWQEAKVHVLTHTLHYGMGVFEGVRAYETAKGPAIFRLQDHTD
CCCEEECCEEEECCEECCCCCCEEEEEEHHHHHCCHHHHHHHHHHCCCCCEEEEEECCHH
RFFNSAHILNMKLPYTKEQINEAHLSAIRENNLPHAYLRPMAFYGSEGMGLRAHNLKVHV
HHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHCEEEEECCCCCCEEEECEEEEE
MVAAWEWPSYMSPEALELGIKVRTSSYTRHHVNITMCKAKANGNYMNSMLALNEALSGGA
EEEEECCCCCCCCHHHEEEEEEEECCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCC
DEALLLDNEGYVAEGSGENVFLVRDGIIYTPELTSCLDGITRKTIMQLAEERGYPVREKR
CCEEEEECCCEEEECCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHC
ITRDELYIADEAFFTGTAAEVMPIRELDGRIIGAGKRGPVTEQLQAVYFDLVRGKLDDDY
CCHHHEEEECCCEECCCHHHEEEHHHHCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
GDWLTYVS
CCCEEECC
>Mature Secondary Structure 
SMAVRDGFIWLDGELVPWQEAKVHVLTHTLHYGMGVFEGVRAYETAKGPAIFRLQDHTD
CCEEECCEEEECCEECCCCCCEEEEEEHHHHHCCHHHHHHHHHHCCCCCEEEEEECCHH
RFFNSAHILNMKLPYTKEQINEAHLSAIRENNLPHAYLRPMAFYGSEGMGLRAHNLKVHV
HHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHCEEEEECCCCCCEEEECEEEEE
MVAAWEWPSYMSPEALELGIKVRTSSYTRHHVNITMCKAKANGNYMNSMLALNEALSGGA
EEEEECCCCCCCCHHHEEEEEEEECCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCC
DEALLLDNEGYVAEGSGENVFLVRDGIIYTPELTSCLDGITRKTIMQLAEERGYPVREKR
CCEEEEECCCEEEECCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHC
ITRDELYIADEAFFTGTAAEVMPIRELDGRIIGAGKRGPVTEQLQAVYFDLVRGKLDDDY
CCHHHEEEECCCEECCCHHHEEEHHHHCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
GDWLTYVS
CCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]