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The map label for this gene is bioD [H]

Identifier: 110835077

GI number: 110835077

Start: 2529471

End: 2530115

Strand: Reverse

Name: bioD [H]

Synonym: ABO_2216

Alternate gene names: 110835077

Gene position: 2530115-2529471 (Counterclockwise)

Preceding gene: 110835078

Following gene: 110835071

Centisome position: 81.09

GC content: 57.67

Gene sequence:

>645_bases
ATGGAAAACCAGAAGCCCCCACTGCCCGCTCTCAAGGGTGTTTTTTTCGTCACCGGCACAGATACCGAAGTCGGTAAGAC
CTGGGTGAGCTGCCGCTTGCTGGAGCGAGCGCGGGAAGCCGGTTTAAGTTGTTACGGACTCAAGCCGGTGGCGGCCGGGT
GTGAGGAAACGTCGGACGGTTGGCGTAATGAAGATGCCTTGCAGCTGATGGCGGCCAGCTCGGTGACGCTGCCTTACGAG
ATAGTAAATCCTGTGGCCTTTAAGGCGCCGGTCGCACCGCATATCGCAGCCCAGCAAGAGGGCAAAGATATCAGTCTTTC
CCGGCTGGTGGGTTATGTGCGGGGCGCCTTGAGCGCCTACCCGGCGGACTTGATTTTGATTGAGGGTGCGGGCGGGTGGC
GAGTGCCGCTGAACAGTCGAGAAATGTTGTCCGGGTTGGCCAAAGAGCTGGATGTGCCAGTGATTCAGGTTGTTGGCATG
AAGCTGGGTTGTATCAATCATGCCTTGCTGACCGCCGATGCGATCGAAAAGGATGGTTTACGCTACGCCGGCACCATGGC
GAACTGCTTTGGAGAAATGGCGGTGCAGGAAGAAAACCTGCTTACTCTACGCCAGCATTTACCCGGTGCCTTCGCGCTGG
TTTGA

Upstream 100 bases:

>100_bases
GGGCCGCAAGTATTGGTGCCGTGCGACATCTTTCCCACGTTGCACCTTTACGCTTGTTGCTTGTCAGCAAACAAACCGCT
CCGTCTTTCAGAGGTTAACC

Downstream 100 bases:

>100_bases
TCGGCAAAATCAGCGCATTTCCATTGCTCTTTCGCGCCATTGTCACCTTTAACGGGGGGTACAGGGGGGCACAACAGTGC
AACGACCCAAGGCCCATCAT

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MENQKPPLPALKGVFFVTGTDTEVGKTWVSCRLLERAREAGLSCYGLKPVAAGCEETSDGWRNEDALQLMAASSVTLPYE
IVNPVAFKAPVAPHIAAQQEGKDISLSRLVGYVRGALSAYPADLILIEGAGGWRVPLNSREMLSGLAKELDVPVIQVVGM
KLGCINHALLTADAIEKDGLRYAGTMANCFGEMAVQEENLLTLRQHLPGAFALV

Sequences:

>Translated_214_residues
MENQKPPLPALKGVFFVTGTDTEVGKTWVSCRLLERAREAGLSCYGLKPVAAGCEETSDGWRNEDALQLMAASSVTLPYE
IVNPVAFKAPVAPHIAAQQEGKDISLSRLVGYVRGALSAYPADLILIEGAGGWRVPLNSREMLSGLAKELDVPVIQVVGM
KLGCINHALLTADAIEKDGLRYAGTMANCFGEMAVQEENLLTLRQHLPGAFALV
>Mature_214_residues
MENQKPPLPALKGVFFVTGTDTEVGKTWVSCRLLERAREAGLSCYGLKPVAAGCEETSDGWRNEDALQLMAASSVTLPYE
IVNPVAFKAPVAPHIAAQQEGKDISLSRLVGYVRGALSAYPADLILIEGAGGWRVPLNSREMLSGLAKELDVPVIQVVGM
KLGCINHALLTADAIEKDGLRYAGTMANCFGEMAVQEENLLTLRQHLPGAFALV

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=174, Percent_Identity=50.5747126436782, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI87081944, Length=178, Percent_Identity=43.2584269662921, Blast_Score=131, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324385, Length=187, Percent_Identity=34.2245989304813, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 22921; Mature: 22921

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQKPPLPALKGVFFVTGTDTEVGKTWVSCRLLERAREAGLSCYGLKPVAAGCEETSDG
CCCCCCCCHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHCCCCCCCCC
WRNEDALQLMAASSVTLPYEIVNPVAFKAPVAPHIAAQQEGKDISLSRLVGYVRGALSAY
CCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHC
PADLILIEGAGGWRVPLNSREMLSGLAKELDVPVIQVVGMKLGCINHALLTADAIEKDGL
CCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RYAGTMANCFGEMAVQEENLLTLRQHLPGAFALV
CHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECC
>Mature Secondary Structure
MENQKPPLPALKGVFFVTGTDTEVGKTWVSCRLLERAREAGLSCYGLKPVAAGCEETSDG
CCCCCCCCHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHCCCCCCCCC
WRNEDALQLMAASSVTLPYEIVNPVAFKAPVAPHIAAQQEGKDISLSRLVGYVRGALSAY
CCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHC
PADLILIEGAGGWRVPLNSREMLSGLAKELDVPVIQVVGMKLGCINHALLTADAIEKDGL
CCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RYAGTMANCFGEMAVQEENLLTLRQHLPGAFALV
CHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA