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The map label for this gene is bioC [H]

Identifier: 110835078

GI number: 110835078

Start: 2530295

End: 2531173

Strand: Reverse

Name: bioC [H]

Synonym: ABO_2217

Alternate gene names: 110835078

Gene position: 2531173-2530295 (Counterclockwise)

Preceding gene: 110835079

Following gene: 110835077

Centisome position: 81.12

GC content: 59.39

Gene sequence:

>879_bases
ATGTACCCTTCCTGTCGACCCCGGACACCTTTACCCAGGCCGTGTATGACTTTTATCGCGACTATCAGTTGGTCCGCTGA
GGCGCCCGTGGATACTCCCGTGGAGCGCTCAGGAAAGGCGGTAGTGAGCCAGCACTTTGGCCGAGCTGCGCGTAGTTATG
ATGAACACGCCGTGCTGCAGTTGGCGGTGGGGCGATCATTGGTGCAGCGCCTGCCAGAAGCGTTACCGATAAATCATGCG
CTGGATTTGGGGTGTGCCACGGCGCCTTTTGCTCGCGCTCAGCAACAGGCGTTGCCGGATGTGCAGTGGCAGGCGGTTGA
TTTGTCTTCGGCCATGCTGGCCGAAGCGGCAGAGCGCGGACGGCTGGATGAGACCTACCAACCCCTGTGTGCTGACGCCG
AAAACCTGCCCCTGTCGACAAACTCTCAGGGTCTGGTGTTCAGTTGTTTTGCCCTGCAATGGTGTGATCCGCAAGTGGTT
ATGGCAGAGATCAACCGGGTGTTGGCTCCGGGCGGACGTTTGCTGCTGGCGGTGCCGTTGGCAGGGTCTCTGGCCGAGTT
GCAATCGAGCTGGCAGCGAGTGAATCATCGCCCCCATGTCAATGCGTTGCCGTCGTTGGCGGATTGGCGCAGTGCGGCTT
TTCAGGCGGGTTTTGCGGATGCGCAGCTTCAGCAGCAGGTGATGGTGGAATACTATGATTCGGTGAAAGCCATCGCCCGT
CGCTTGAAAGCCACCGGCGCGGATCATGTAAGCGGTGCCTCAGGCCTTACCGGTAAAAATGCCTGGCAGGCCATGGTGAA
AGAATATGAGGCCCGGCGAACGCAGCAAGGCTTGCCGCTGACCTGGAACGTGCTGTTCCTGGAAGCGGAAAAGAGTTGA

Upstream 100 bases:

>100_bases
GTGTTCGGTGAACATGATCATATCGTGCCGGCGGCAGTCATGGCCGCGGTGGAGCCGTTGATTGGTAATGGCCGCACGGC
CTTGATTGAGCAGGTGGCCC

Downstream 100 bases:

>100_bases
GCGAATAAGCCCCAGGTTTCAACGCGCGCCAGCCTCCGTTGTTTTTTCCAATTTTCTCCGCGCCAGAATCGTGACACGCG
GGCCGCAAGTATTGGTGCCG

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MYPSCRPRTPLPRPCMTFIATISWSAEAPVDTPVERSGKAVVSQHFGRAARSYDEHAVLQLAVGRSLVQRLPEALPINHA
LDLGCATAPFARAQQQALPDVQWQAVDLSSAMLAEAAERGRLDETYQPLCADAENLPLSTNSQGLVFSCFALQWCDPQVV
MAEINRVLAPGGRLLLAVPLAGSLAELQSSWQRVNHRPHVNALPSLADWRSAAFQAGFADAQLQQQVMVEYYDSVKAIAR
RLKATGADHVSGASGLTGKNAWQAMVKEYEARRTQQGLPLTWNVLFLEAEKS

Sequences:

>Translated_292_residues
MYPSCRPRTPLPRPCMTFIATISWSAEAPVDTPVERSGKAVVSQHFGRAARSYDEHAVLQLAVGRSLVQRLPEALPINHA
LDLGCATAPFARAQQQALPDVQWQAVDLSSAMLAEAAERGRLDETYQPLCADAENLPLSTNSQGLVFSCFALQWCDPQVV
MAEINRVLAPGGRLLLAVPLAGSLAELQSSWQRVNHRPHVNALPSLADWRSAAFQAGFADAQLQQQVMVEYYDSVKAIAR
RLKATGADHVSGASGLTGKNAWQAMVKEYEARRTQQGLPLTWNVLFLEAEKS
>Mature_292_residues
MYPSCRPRTPLPRPCMTFIATISWSAEAPVDTPVERSGKAVVSQHFGRAARSYDEHAVLQLAVGRSLVQRLPEALPINHA
LDLGCATAPFARAQQQALPDVQWQAVDLSSAMLAEAAERGRLDETYQPLCADAENLPLSTNSQGLVFSCFALQWCDPQVV
MAEINRVLAPGGRLLLAVPLAGSLAELQSSWQRVNHRPHVNALPSLADWRSAAFQAGFADAQLQQQVMVEYYDSVKAIAR
RLKATGADHVSGASGLTGKNAWQAMVKEYEARRTQQGLPLTWNVLFLEAEKS

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=199, Percent_Identity=31.1557788944724, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 31900; Mature: 31900

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPSCRPRTPLPRPCMTFIATISWSAEAPVDTPVERSGKAVVSQHFGRAARSYDEHAVLQ
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCHHHHHHH
LAVGRSLVQRLPEALPINHALDLGCATAPFARAQQQALPDVQWQAVDLSSAMLAEAAERG
HHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCC
RLDETYQPLCADAENLPLSTNSQGLVFSCFALQWCDPQVVMAEINRVLAPGGRLLLAVPL
CCCHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHCCCCCEEEEECC
AGSLAELQSSWQRVNHRPHVNALPSLADWRSAAFQAGFADAQLQQQVMVEYYDSVKAIAR
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RLKATGADHVSGASGLTGKNAWQAMVKEYEARRTQQGLPLTWNVLFLEAEKS
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
>Mature Secondary Structure
MYPSCRPRTPLPRPCMTFIATISWSAEAPVDTPVERSGKAVVSQHFGRAARSYDEHAVLQ
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCHHHHHHH
LAVGRSLVQRLPEALPINHALDLGCATAPFARAQQQALPDVQWQAVDLSSAMLAEAAERG
HHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCC
RLDETYQPLCADAENLPLSTNSQGLVFSCFALQWCDPQVVMAEINRVLAPGGRLLLAVPL
CCCHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHCCCCCEEEEECC
AGSLAELQSSWQRVNHRPHVNALPSLADWRSAAFQAGFADAQLQQQVMVEYYDSVKAIAR
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RLKATGADHVSGASGLTGKNAWQAMVKEYEARRTQQGLPLTWNVLFLEAEKS
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]