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The map label for this gene is dadX

Identifier: 110835047

GI number: 110835047

Start: 2496009

End: 2497070

Strand: Reverse

Name: dadX

Synonym: ABO_2186

Alternate gene names: 110835047

Gene position: 2497070-2496009 (Counterclockwise)

Preceding gene: 110835048

Following gene: 110835046

Centisome position: 80.03

GC content: 58.29

Gene sequence:

>1062_bases
ATGAGAGGCACGCGCGTAGAAATTCGTCTCGCCGCGCTCAGGAACAACGCACTCCGCGCAGCGGAGTTGGCCGGTGATGC
TCAAGTGTTTGCTATGGTTAAGGCTAATGGTTACGGCCATGGGCTGTTGCTGGCGGCAGAGACCATGCTCGATAGCGTGT
CGGGTTTGGGCGTGGCAGTGCTGGACGAGGCGCGGACGCTGCGTGAGCATGGTATAGCCTTGCCAATATTGGTTGCCGAA
GGGTTCTTCGATGCGGAAGAGCTAGAGGCAGCGGCGCGACTCTCGCTTGAGGTGGTGGTGCATTCCTTATGGCAAGTGGA
GTTGCTGCTGGCGAACCCGTGCCCGGTACGTATTTGGTTGAAAGTGAATGCGGGGATGAATCGTCTGGGTTTGCGCCCGA
ATGAAGCTTTGAGCGCGGCTGCACGGTTAAGCCAAGCAGGTAACGCTCCGGTCGGCGTGATGAGCCATTTTGCCTGTGCG
GATATGGATGAGGATATCCATTCCGAAAAACAGCTACTGCTGGCGGGAAGTGTAGCAGAGCAATTGCAGCTGCCGCTGTC
TGCTTCAAACTCTGCTGCTTTACTGCGTTACCCTCGTGCCCATGCCCAGCGAGTGCGGCCGGGGATCATGTTGTATGGCT
CATCGCCGTTTAACTGGCAGACTGCTGCGGAACTTGGTCTGCAAGTCAGCCATCGCTTCAGTGCACGCTTGATCGCCATT
AATGCTGTTGAGGCTGGTGAAAGCGTGGGTTATGGCGCTACCTGGACTGCCTCAGATCCACGACAAATCGGGGTGGTGGC
AGTGGGCTATGGCGATGGCTACCCACGCCACGCGCCCAGCGGGACGCCGGTAGCGGTGAACGGGGTCGTTACGACGCTGG
TGGGGCGAGTTTCCATGGATATGATCACCATCGATGTGACCGGCTTGAGTGCCAGCGTGGGGGATGAGGTGGAGTTGTGG
GGTGACGTGGTCGATGTGGATGACGTGGCCCGTGCCTGTGGGACAATCAGCTATGAGCTGTTCTGCCAGATCACGCAAAG
ACCGGAACGCACTATCGTCTGA

Upstream 100 bases:

>100_bases
GGATGAATAAAACGCAGAATGAAGGCGGTTGGATGCTGAATGCGCAGCCCTCTTTTTTAAAGGTTAACCGTCAGCCACTA
GGCGCTGGACTGCAATTTTT

Downstream 100 bases:

>100_bases
TCCGAAGGTCAGTTTAGGCGTCCCGCTTGAGGCGAGAACATCAAGTGCGAATTCATCACAGAGCGTGCTGAACGCTCAGA
GTAAACCATTTTATCCTCAG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MRGTRVEIRLAALRNNALRAAELAGDAQVFAMVKANGYGHGLLLAAETMLDSVSGLGVAVLDEARTLREHGIALPILVAE
GFFDAEELEAAARLSLEVVVHSLWQVELLLANPCPVRIWLKVNAGMNRLGLRPNEALSAAARLSQAGNAPVGVMSHFACA
DMDEDIHSEKQLLLAGSVAEQLQLPLSASNSAALLRYPRAHAQRVRPGIMLYGSSPFNWQTAAELGLQVSHRFSARLIAI
NAVEAGESVGYGATWTASDPRQIGVVAVGYGDGYPRHAPSGTPVAVNGVVTTLVGRVSMDMITIDVTGLSASVGDEVELW
GDVVDVDDVARACGTISYELFCQITQRPERTIV

Sequences:

>Translated_353_residues
MRGTRVEIRLAALRNNALRAAELAGDAQVFAMVKANGYGHGLLLAAETMLDSVSGLGVAVLDEARTLREHGIALPILVAE
GFFDAEELEAAARLSLEVVVHSLWQVELLLANPCPVRIWLKVNAGMNRLGLRPNEALSAAARLSQAGNAPVGVMSHFACA
DMDEDIHSEKQLLLAGSVAEQLQLPLSASNSAALLRYPRAHAQRVRPGIMLYGSSPFNWQTAAELGLQVSHRFSARLIAI
NAVEAGESVGYGATWTASDPRQIGVVAVGYGDGYPRHAPSGTPVAVNGVVTTLVGRVSMDMITIDVTGLSASVGDEVELW
GDVVDVDDVARACGTISYELFCQITQRPERTIV
>Mature_353_residues
MRGTRVEIRLAALRNNALRAAELAGDAQVFAMVKANGYGHGLLLAAETMLDSVSGLGVAVLDEARTLREHGIALPILVAE
GFFDAEELEAAARLSLEVVVHSLWQVELLLANPCPVRIWLKVNAGMNRLGLRPNEALSAAARLSQAGNAPVGVMSHFACA
DMDEDIHSEKQLLLAGSVAEQLQLPLSASNSAALLRYPRAHAQRVRPGIMLYGSSPFNWQTAAELGLQVSHRFSARLIAI
NAVEAGESVGYGATWTASDPRQIGVVAVGYGDGYPRHAPSGTPVAVNGVVTTLVGRVSMDMITIDVTGLSASVGDEVELW
GDVVDVDDVARACGTISYELFCQITQRPERTIV

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1787439, Length=351, Percent_Identity=43.8746438746439, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1790487, Length=353, Percent_Identity=43.0594900849858, Blast_Score=258, Evalue=5e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_ALCBS (Q0VMG4)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693906.1
- ProteinModelPortal:   Q0VMG4
- SMR:   Q0VMG4
- STRING:   Q0VMG4
- GeneID:   4213284
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2186
- NMPDR:   fig|393595.12.peg.2186
- eggNOG:   COG0787
- HOGENOM:   HBG712172
- OMA:   AMRIGIV
- PhylomeDB:   Q0VMG4
- BioCyc:   ABOR393595:ABO_2186-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 37526; Mature: 37526

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 34-34 ACT_SITE 251-251

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGTRVEIRLAALRNNALRAAELAGDAQVFAMVKANGYGHGLLLAAETMLDSVSGLGVAV
CCCCEEEEEEEEECCCCHHHHHHCCCEEEEEEEEECCCCCEEEEEHHHHHHHHCCCCEEE
LDEARTLREHGIALPILVAEGFFDAEELEAAARLSLEVVVHSLWQVELLLANPCPVRIWL
HHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEE
KVNAGMNRLGLRPNEALSAAARLSQAGNAPVGVMSHFACADMDEDIHSEKQLLLAGSVAE
EEECCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCEEEEECCHHH
QLQLPLSASNSAALLRYPRAHAQRVRPGIMLYGSSPFNWQTAAELGLQVSHRFSARLIAI
HHCCCCCCCCCEEEEECCHHHHHHCCCCEEEECCCCCCCHHHHHHCCEEECCCCEEEEEE
NAVEAGESVGYGATWTASDPRQIGVVAVGYGDGYPRHAPSGTPVAVNGVVTTLVGRVSMD
EEEECCCCCCCCEEECCCCCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHEEE
MITIDVTGLSASVGDEVELWGDVVDVDDVARACGTISYELFCQITQRPERTIV
EEEEEEECCCCCCCCCCEECCCEECHHHHHHHHCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MRGTRVEIRLAALRNNALRAAELAGDAQVFAMVKANGYGHGLLLAAETMLDSVSGLGVAV
CCCCEEEEEEEEECCCCHHHHHHCCCEEEEEEEEECCCCCEEEEEHHHHHHHHCCCCEEE
LDEARTLREHGIALPILVAEGFFDAEELEAAARLSLEVVVHSLWQVELLLANPCPVRIWL
HHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEE
KVNAGMNRLGLRPNEALSAAARLSQAGNAPVGVMSHFACADMDEDIHSEKQLLLAGSVAE
EEECCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCEEEEECCHHH
QLQLPLSASNSAALLRYPRAHAQRVRPGIMLYGSSPFNWQTAAELGLQVSHRFSARLIAI
HHCCCCCCCCCEEEEECCHHHHHHCCCCEEEECCCCCCCHHHHHHCCEEECCCCEEEEEE
NAVEAGESVGYGATWTASDPRQIGVVAVGYGDGYPRHAPSGTPVAVNGVVTTLVGRVSMD
EEEECCCCCCCCEEECCCCCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHEEE
MITIDVTGLSASVGDEVELWGDVVDVDDVARACGTISYELFCQITQRPERTIV
EEEEEEECCCCCCCCCCEECCCEECHHHHHHHHCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA