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The map label for this gene is regB [H]

Identifier: 110834893

GI number: 110834893

Start: 2319198

End: 2320559

Strand: Reverse

Name: regB [H]

Synonym: ABO_2032

Alternate gene names: 110834893

Gene position: 2320559-2319198 (Counterclockwise)

Preceding gene: 110834894

Following gene: 110834892

Centisome position: 74.37

GC content: 53.67

Gene sequence:

>1362_bases
ATGGAAATCATGTCATCGTCCTCACCCTCTAAGACTCCTCCATCGGGATCGTTATTTTCTGCACTGCGCCGCAGTAGCGA
CGACCTGACCGGCCGCAAGAACCTGCAGTTACTGATACAGCTGCGCTGGATTGCCATGTTCGGCCAGTTCGCCACCATTT
TGGTGGTTAATTACGGCTTTGATATTGAGCTACCCGTGGCGCAAATGCTGATGGTGCTGTTTGGTCTGCTGTTGCTCAAT
GCGGTCAGTTTGTTGCGAATGAGGCTGCCAAAGACCATTGGCAATACCGAGTTATTCCTTTCCCTGCTGATTGATGTGGC
CACGCTGACCATGCTGTTGGCGTTGAGCGGCGGTGCTTCGAACCCGTTTGTGTTTCTGTATTTACTGCAAGTGATTCTGG
GTGCGGTGTTGCTGGAGGTGTGGTCTACCTGGGTGATTCTGGTGACCACCACATTGTGCTTCGGCTGGCTGGCCTGGTAT
GGCCACCCATTGCCTATGCCGTTGGATCATTCCGAAGGGCTATTCAGTCTTTACATCGAAGGCATGTTTATCTGTTTTGT
GCTCAATGGTGTGCTGCTAGTGGTTTTCATTAACCGTATTACCCGTAATCGACGTCAGCGTGACGAGCATCTGGCGCAGT
TGCGTCAGCGAGCAGCAGAAGAAGAGCACATTGTGCGTATGGGGTTGTTGGCTTCCGGCGCGGCCCACGAGCTGGGAACG
CCGCTGGCGACCCTGTCCGTGATTCTGGGTGACTGGAGGCACATGGAGCCGTTCAAATCCAATGGTGATTTGGCCCAGGA
AATTACTGAGATGCAGACACAGGTACTTCGCTGCAAATCTATTGTTAGCGGTATCTTGTTATCGGCGGGCGAGGCACGGG
GGGAATCTTCAGAAGGAACTACGGTACGCGCGTTTCTGGATGATTTGGTGGACGAGTGGCGCGAAACGCGCCCGGTGAAA
GATTTTTCTTATAGCAATGAGTTTGGGGAAGACCTGAGTATCGTGTCCGACTCAGCCCTCCGGCAGAGCATTCATAATGT
ATTGGATAACGCACTGGAAGCCTCGCCAAATTGGGTGCGGCTGAGTGTGTACCGTGAAGGTAAAACCCTGCTGGTGTCGG
TGGCAGACCGGGGGCCGGGCTTCGCACAGGCAATGCTCGACAATCTTGGTCGCCCCTATCAGTCCAGCAAGGGGCGACCG
GGCAGTGGCCTTGGGCTGTTTTTAGTGATGAATGTACTGCGCACGTTAGGGGGTAATCTGAAAGCGAGTAATTTGGTGCA
GGGCGGCGCATTAGTAACGTTGTCTTTGCCACTTTCCGTGGTCGCCCTGAAACAGGAAAGAGGAGAAACCAACGGTGACT
GA

Upstream 100 bases:

>100_bases
TCTAGTCTACGCCATCACTTGGTTTGCCCTTGCCTTCGGCATGGTGCTGGCGGCTTGGCTGGTGCTACGGGATTCACCCC
GAACGCGCTAAACTGGGGCT

Downstream 100 bases:

>100_bases
TACGTTGCAGGACGAAAAACTGCTATTGATTGTAGAAGATGATGACGCCTTTGCTCGCACCTTGACCCGTTCGTTCGAGA
GGCGAGGATATCGAGTTATT

Product: two-component, sensor histidine protein kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MEIMSSSSPSKTPPSGSLFSALRRSSDDLTGRKNLQLLIQLRWIAMFGQFATILVVNYGFDIELPVAQMLMVLFGLLLLN
AVSLLRMRLPKTIGNTELFLSLLIDVATLTMLLALSGGASNPFVFLYLLQVILGAVLLEVWSTWVILVTTTLCFGWLAWY
GHPLPMPLDHSEGLFSLYIEGMFICFVLNGVLLVVFINRITRNRRQRDEHLAQLRQRAAEEEHIVRMGLLASGAAHELGT
PLATLSVILGDWRHMEPFKSNGDLAQEITEMQTQVLRCKSIVSGILLSAGEARGESSEGTTVRAFLDDLVDEWRETRPVK
DFSYSNEFGEDLSIVSDSALRQSIHNVLDNALEASPNWVRLSVYREGKTLLVSVADRGPGFAQAMLDNLGRPYQSSKGRP
GSGLGLFLVMNVLRTLGGNLKASNLVQGGALVTLSLPLSVVALKQERGETNGD

Sequences:

>Translated_453_residues
MEIMSSSSPSKTPPSGSLFSALRRSSDDLTGRKNLQLLIQLRWIAMFGQFATILVVNYGFDIELPVAQMLMVLFGLLLLN
AVSLLRMRLPKTIGNTELFLSLLIDVATLTMLLALSGGASNPFVFLYLLQVILGAVLLEVWSTWVILVTTTLCFGWLAWY
GHPLPMPLDHSEGLFSLYIEGMFICFVLNGVLLVVFINRITRNRRQRDEHLAQLRQRAAEEEHIVRMGLLASGAAHELGT
PLATLSVILGDWRHMEPFKSNGDLAQEITEMQTQVLRCKSIVSGILLSAGEARGESSEGTTVRAFLDDLVDEWRETRPVK
DFSYSNEFGEDLSIVSDSALRQSIHNVLDNALEASPNWVRLSVYREGKTLLVSVADRGPGFAQAMLDNLGRPYQSSKGRP
GSGLGLFLVMNVLRTLGGNLKASNLVQGGALVTLSLPLSVVALKQERGETNGD
>Mature_453_residues
MEIMSSSSPSKTPPSGSLFSALRRSSDDLTGRKNLQLLIQLRWIAMFGQFATILVVNYGFDIELPVAQMLMVLFGLLLLN
AVSLLRMRLPKTIGNTELFLSLLIDVATLTMLLALSGGASNPFVFLYLLQVILGAVLLEVWSTWVILVTTTLCFGWLAWY
GHPLPMPLDHSEGLFSLYIEGMFICFVLNGVLLVVFINRITRNRRQRDEHLAQLRQRAAEEEHIVRMGLLASGAAHELGT
PLATLSVILGDWRHMEPFKSNGDLAQEITEMQTQVLRCKSIVSGILLSAGEARGESSEGTTVRAFLDDLVDEWRETRPVK
DFSYSNEFGEDLSIVSDSALRQSIHNVLDNALEASPNWVRLSVYREGKTLLVSVADRGPGFAQAMLDNLGRPYQSSKGRP
GSGLGLFLVMNVLRTLGGNLKASNLVQGGALVTLSLPLSVVALKQERGETNGD

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=263, Percent_Identity=25.4752851711027, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49818; Mature: 49818

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIMSSSSPSKTPPSGSLFSALRRSSDDLTGRKNLQLLIQLRWIAMFGQFATILVVNYGF
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCC
DIELPVAQMLMVLFGLLLLNAVSLLRMRLPKTIGNTELFLSLLIDVATLTMLLALSGGAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NPFVFLYLLQVILGAVLLEVWSTWVILVTTTLCFGWLAWYGHPLPMPLDHSEGLFSLYIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
GMFICFVLNGVLLVVFINRITRNRRQRDEHLAQLRQRAAEEEHIVRMGLLASGAAHELGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
PLATLSVILGDWRHMEPFKSNGDLAQEITEMQTQVLRCKSIVSGILLSAGEARGESSEGT
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TVRAFLDDLVDEWRETRPVKDFSYSNEFGEDLSIVSDSALRQSIHNVLDNALEASPNWVR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LSVYREGKTLLVSVADRGPGFAQAMLDNLGRPYQSSKGRPGSGLGLFLVMNVLRTLGGNL
EEEEECCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
KASNLVQGGALVTLSLPLSVVALKQERGETNGD
CHHHEECCCEEEEEECCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEIMSSSSPSKTPPSGSLFSALRRSSDDLTGRKNLQLLIQLRWIAMFGQFATILVVNYGF
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCC
DIELPVAQMLMVLFGLLLLNAVSLLRMRLPKTIGNTELFLSLLIDVATLTMLLALSGGAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NPFVFLYLLQVILGAVLLEVWSTWVILVTTTLCFGWLAWYGHPLPMPLDHSEGLFSLYIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
GMFICFVLNGVLLVVFINRITRNRRQRDEHLAQLRQRAAEEEHIVRMGLLASGAAHELGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
PLATLSVILGDWRHMEPFKSNGDLAQEITEMQTQVLRCKSIVSGILLSAGEARGESSEGT
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TVRAFLDDLVDEWRETRPVKDFSYSNEFGEDLSIVSDSALRQSIHNVLDNALEASPNWVR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LSVYREGKTLLVSVADRGPGFAQAMLDNLGRPYQSSKGRPGSGLGLFLVMNVLRTLGGNL
EEEEECCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
KASNLVQGGALVTLSLPLSVVALKQERGETNGD
CHHHEECCCEEEEEECCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]