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The map label for this gene is trpD

Identifier: 110834886

GI number: 110834886

Start: 2313732

End: 2314784

Strand: Reverse

Name: trpD

Synonym: ABO_2025

Alternate gene names: 110834886

Gene position: 2314784-2313732 (Counterclockwise)

Preceding gene: 110834887

Following gene: 110834885

Centisome position: 74.19

GC content: 57.55

Gene sequence:

>1053_bases
ATGAATATTCCGCAAGCGCTGGCCAAAGTGGTCGATAATATTGATTTGAGCATCGAGGAAATGCGCGATGTGATGGGCCA
GGTGATGACCGGTGGCGCCACCGATGCACAGATTGGTGCACTGATGGTCGGCCTGCGGATGAAAAGCGAATCTCTGGATG
AAATCACTGGCGCCGTTATGGTTATGCGCGAGCTGGTTACCGGGGTGACGGTGGAGAACCGTCAGTATCTGGTGGACATC
GTCGGTACCGGCGGCGATGGCGCCAATTTGTTCAATGTGTCCACCGCCAGTAGTTTTGTGGCCGCGGCCGCCGGTGCCCA
TGTGGCCAAGCACGGGGGCCGTTCGGTGAGCTCGCAAAGTGGTTCCGCTGATCTGTTGGAAACGGCGGGTATTGCGCTGG
ACCTAAGCCCGGCACAGATTGGCCAATGTGTGGATAATGTTGGTGTCGGCTTCATGTTTGCGCCGAACCATCACAAGGCT
ATGAAGTATGCCGTGGGGCCGCGCAAGGAGCTGGGTATGCGCACCCTGTTTAATATTCTCGGTCCGATGACCAACCCGGC
CGGGGTTCAGCGGTTGGTGATGGGTGTATTCTCGGAAAAGCTGTGTCGTCCGCTGGCGGAAGTCATGGGGCGCCTGGGCG
GCGAGCACATCATGGTGGTGCACAGTAAAGACGGCCTGGATGAGATCAGCCTGGCGGCACGTACTCATGTGGCGGAGTTC
AGGGATGGTGAGGTGAAAGAGTACGACCTGACACCGGAAGATCTTGGGCTGGGATCCGATTCCCTGGTCGGCCTTGATGT
AACTGACTCAAAAGCGTCTTTGGCGCTGATCAAAGATGCGTTTGGCAAGCGCACCACAGAAGCCGCTTGCAAGGCTGCAG
ACATGATTGCCCTGAACGCGGGGGCGGCCATTTATGTCAGTGGTATTACTCGCACTCACAAGGAAGGGGTCAGCATGGCG
GAAGACCTGATCCACAATGGAGAAGCGGCAGAACGCATGCGCGAGCTGGCCCAGTTCAGCACGGCCCTCAAGGTTGGCGA
CGAATCCCATTAA

Upstream 100 bases:

>100_bases
CGATTGAAGGGGTGCAATATCACCCTGAGTCTATTTTGAGTGAGCACGGTCATGCCCTGCTTGAGAATTTTTTAAAGCTG
GATGAGCAGGGGGAAGGGGC

Downstream 100 bases:

>100_bases
GGAGCGAGGTTATGAGCACAGGCACCATTCTCGATAAGATTATCGCCCGCAAGCAGGAGGAGATTGCCATTGGCAAGAAC
CATTATACGCTGGGTGATCT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MNIPQALAKVVDNIDLSIEEMRDVMGQVMTGGATDAQIGALMVGLRMKSESLDEITGAVMVMRELVTGVTVENRQYLVDI
VGTGGDGANLFNVSTASSFVAAAAGAHVAKHGGRSVSSQSGSADLLETAGIALDLSPAQIGQCVDNVGVGFMFAPNHHKA
MKYAVGPRKELGMRTLFNILGPMTNPAGVQRLVMGVFSEKLCRPLAEVMGRLGGEHIMVVHSKDGLDEISLAARTHVAEF
RDGEVKEYDLTPEDLGLGSDSLVGLDVTDSKASLALIKDAFGKRTTEAACKAADMIALNAGAAIYVSGITRTHKEGVSMA
EDLIHNGEAAERMRELAQFSTALKVGDESH

Sequences:

>Translated_350_residues
MNIPQALAKVVDNIDLSIEEMRDVMGQVMTGGATDAQIGALMVGLRMKSESLDEITGAVMVMRELVTGVTVENRQYLVDI
VGTGGDGANLFNVSTASSFVAAAAGAHVAKHGGRSVSSQSGSADLLETAGIALDLSPAQIGQCVDNVGVGFMFAPNHHKA
MKYAVGPRKELGMRTLFNILGPMTNPAGVQRLVMGVFSEKLCRPLAEVMGRLGGEHIMVVHSKDGLDEISLAARTHVAEF
RDGEVKEYDLTPEDLGLGSDSLVGLDVTDSKASLALIKDAFGKRTTEAACKAADMIALNAGAAIYVSGITRTHKEGVSMA
EDLIHNGEAAERMRELAQFSTALKVGDESH
>Mature_350_residues
MNIPQALAKVVDNIDLSIEEMRDVMGQVMTGGATDAQIGALMVGLRMKSESLDEITGAVMVMRELVTGVTVENRQYLVDI
VGTGGDGANLFNVSTASSFVAAAAGAHVAKHGGRSVSSQSGSADLLETAGIALDLSPAQIGQCVDNVGVGFMFAPNHHKA
MKYAVGPRKELGMRTLFNILGPMTNPAGVQRLVMGVFSEKLCRPLAEVMGRLGGEHIMVVHSKDGLDEISLAARTHVAEF
RDGEVKEYDLTPEDLGLGSDSLVGLDVTDSKASLALIKDAFGKRTTEAACKAADMIALNAGAAIYVSGITRTHKEGVSMA
EDLIHNGEAAERMRELAQFSTALKVGDESH

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=252, Percent_Identity=46.031746031746, Blast_Score=194, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6320561, Length=325, Percent_Identity=29.5384615384615, Blast_Score=123, Evalue=5e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_ALCBS (Q0VMX5)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693745.1
- ProteinModelPortal:   Q0VMX5
- SMR:   Q0VMX5
- STRING:   Q0VMX5
- GeneID:   4211819
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2025
- NMPDR:   fig|393595.12.peg.2027
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q0VMX5
- BioCyc:   ABOR393595:ABO_2025-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36826; Mature: 36826

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPQALAKVVDNIDLSIEEMRDVMGQVMTGGATDAQIGALMVGLRMKSESLDEITGAVM
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
VMRELVTGVTVENRQYLVDIVGTGGDGANLFNVSTASSFVAAAAGAHVAKHGGRSVSSQS
HHHHHHHCCEECCCEEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCC
GSADLLETAGIALDLSPAQIGQCVDNVGVGFMFAPNHHKAMKYAVGPRKELGMRTLFNIL
CCCHHHHHCCCEEECCHHHHHHHHHHCCCCEEECCCCCHHHHHCCCCHHHHHHHHHHHHH
GPMTNPAGVQRLVMGVFSEKLCRPLAEVMGRLGGEHIMVVHSKDGLDEISLAARTHVAEF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHC
RDGEVKEYDLTPEDLGLGSDSLVGLDVTDSKASLALIKDAFGKRTTEAACKAADMIALNA
CCCCCEEECCCHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHEEECC
GAAIYVSGITRTHKEGVSMAEDLIHNGEAAERMRELAQFSTALKVGDESH
CCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNIPQALAKVVDNIDLSIEEMRDVMGQVMTGGATDAQIGALMVGLRMKSESLDEITGAVM
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
VMRELVTGVTVENRQYLVDIVGTGGDGANLFNVSTASSFVAAAAGAHVAKHGGRSVSSQS
HHHHHHHCCEECCCEEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCC
GSADLLETAGIALDLSPAQIGQCVDNVGVGFMFAPNHHKAMKYAVGPRKELGMRTLFNIL
CCCHHHHHCCCEEECCHHHHHHHHHHCCCCEEECCCCCHHHHHCCCCHHHHHHHHHHHHH
GPMTNPAGVQRLVMGVFSEKLCRPLAEVMGRLGGEHIMVVHSKDGLDEISLAARTHVAEF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHC
RDGEVKEYDLTPEDLGLGSDSLVGLDVTDSKASLALIKDAFGKRTTEAACKAADMIALNA
CCCCCEEECCCHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHEEECC
GAAIYVSGITRTHKEGVSMAEDLIHNGEAAERMRELAQFSTALKVGDESH
CCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA