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The map label for this gene is trpG [H]

Identifier: 110834887

GI number: 110834887

Start: 2314781

End: 2315383

Strand: Reverse

Name: trpG [H]

Synonym: ABO_2026

Alternate gene names: 110834887

Gene position: 2315383-2314781 (Counterclockwise)

Preceding gene: 110834888

Following gene: 110834886

Centisome position: 74.21

GC content: 53.07

Gene sequence:

>603_bases
ATGCGCGTGCTGATGATCGATAATTACGACAGTTTTACCTACAACCTGGTGCAGTACCTACAGGAGCTGGGTGCTGAGGT
GCTGGTGCACCGCAACGACCAGATTAGCCTGGAAGAGATTGAACAGCTGAACCCTGATCGGTTGATGATTTCCCCTGGCC
CTTGTACCCCCAATGAAGCGGGTATCTCCCTCGCAGCGATTAAGCACTTTGCTGGCAAGCTGCCGATTCTTGGTGTGTGT
TTGGGGCATCAGGCGATTGGGCAAGCGTTTGGGGGCCAGGTCATTCGGGCCCGCCAAGTGATGCATGGTAAAACCTCGCC
GATTTACCACAATGGTGTGGGCGTGTTCCGTGATTTGCCATCGCCCTATACGGCAACTCGCTACCATTCTCTGGTGGTGG
AAAAAGACAGCCTTCCGGATTGTTTGGAAATGACGGCCTGGACTCTGAAAGACGATGGCAGCGTCGATGAAATCATGGGT
ATGCGTCACAAGACGCTGCCGATTGAAGGGGTGCAATATCACCCTGAGTCTATTTTGAGTGAGCACGGTCATGCCCTGCT
TGAGAATTTTTTAAAGCTGGATGAGCAGGGGGAAGGGGCATGA

Upstream 100 bases:

>100_bases
AGTCTGAATGGGACGAGACCATGAATAAAGCCCGGGCAGTATTCCGAGCGGTAAACATGGCATTGGGTGGTCTCAACCTG
GCAGACGGAGGACAGTAATA

Downstream 100 bases:

>100_bases
ATATTCCGCAAGCGCTGGCCAAAGTGGTCGATAATATTGATTTGAGCATCGAGGAAATGCGCGATGTGATGGGCCAGGTG
ATGACCGGTGGCGCCACCGA

Product: anthranilate synthase, component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MRVLMIDNYDSFTYNLVQYLQELGAEVLVHRNDQISLEEIEQLNPDRLMISPGPCTPNEAGISLAAIKHFAGKLPILGVC
LGHQAIGQAFGGQVIRARQVMHGKTSPIYHNGVGVFRDLPSPYTATRYHSLVVEKDSLPDCLEMTAWTLKDDGSVDEIMG
MRHKTLPIEGVQYHPESILSEHGHALLENFLKLDEQGEGA

Sequences:

>Translated_200_residues
MRVLMIDNYDSFTYNLVQYLQELGAEVLVHRNDQISLEEIEQLNPDRLMISPGPCTPNEAGISLAAIKHFAGKLPILGVC
LGHQAIGQAFGGQVIRARQVMHGKTSPIYHNGVGVFRDLPSPYTATRYHSLVVEKDSLPDCLEMTAWTLKDDGSVDEIMG
MRHKTLPIEGVQYHPESILSEHGHALLENFLKLDEQGEGA
>Mature_200_residues
MRVLMIDNYDSFTYNLVQYLQELGAEVLVHRNDQISLEEIEQLNPDRLMISPGPCTPNEAGISLAAIKHFAGKLPILGVC
LGHQAIGQAFGGQVIRARQVMHGKTSPIYHNGVGVFRDLPSPYTATRYHSLVVEKDSLPDCLEMTAWTLKDDGSVDEIMG
MRHKTLPIEGVQYHPESILSEHGHALLENFLKLDEQGEGA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=66.6666666666667, Blast_Score=271, Evalue=3e-74,
Organism=Escherichia coli, GI1787517, Length=197, Percent_Identity=42.1319796954315, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786215, Length=184, Percent_Identity=27.1739130434783, Blast_Score=70, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322638, Length=192, Percent_Identity=50.5208333333333, Blast_Score=206, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6324361, Length=215, Percent_Identity=34.8837209302326, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 22189; Mature: 22189

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLMIDNYDSFTYNLVQYLQELGAEVLVHRNDQISLEEIEQLNPDRLMISPGPCTPNEA
CEEEEECCCCCHHHHHHHHHHHHCHHEEEECCCCCCHHHHHHCCCCEEEECCCCCCCCCC
GISLAAIKHFAGKLPILGVCLGHQAIGQAFGGQVIRARQVMHGKTSPIYHNGVGVFRDLP
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEECCCHHHHCCC
SPYTATRYHSLVVEKDSLPDCLEMTAWTLKDDGSVDEIMGMRHKTLPIEGVQYHPESILS
CCCCHHHHHEEEEECCCCCHHHHHHEEECCCCCCHHHHHCCCCCCCCCCCCEECHHHHHH
EHGHALLENFLKLDEQGEGA
HCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRVLMIDNYDSFTYNLVQYLQELGAEVLVHRNDQISLEEIEQLNPDRLMISPGPCTPNEA
CEEEEECCCCCHHHHHHHHHHHHCHHEEEECCCCCCHHHHHHCCCCEEEECCCCCCCCCC
GISLAAIKHFAGKLPILGVCLGHQAIGQAFGGQVIRARQVMHGKTSPIYHNGVGVFRDLP
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEECCCHHHHCCC
SPYTATRYHSLVVEKDSLPDCLEMTAWTLKDDGSVDEIMGMRHKTLPIEGVQYHPESILS
CCCCHHHHHEEEEECCCCCHHHHHHEEECCCCCCHHHHHCCCCCCCCCCCCEECHHHHHH
EHGHALLENFLKLDEQGEGA
HCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404959; 659439 [H]