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The map label for this gene is luxR [H]

Identifier: 110834848

GI number: 110834848

Start: 2274228

End: 2275133

Strand: Direct

Name: luxR [H]

Synonym: ABO_1987

Alternate gene names: 110834848

Gene position: 2274228-2275133 (Clockwise)

Preceding gene: 110834847

Following gene: 110834850

Centisome position: 72.89

GC content: 52.65

Gene sequence:

>906_bases
ATGACAGCCGCACAACGTAAAGATCTGATACTGGTGGTGGACGACTCCCCAGATTCTCTCGGCATGATTCATCAAGCGTT
GGATCAAGCCGGACTCACTGCTCTTATCGCACTGGAAGGCCAGCAAGCACTGAATATTGCCGAAAAAATGACACCAGATT
TGATCTTGATGGATGCGATCATGCCCAACTTAGATGGCTTCGAAACTTGCCGCCGCCTGAAACAGCATCCAAATCTAGCC
TGCGTTCCAGTAATTTTCATGACCGGACTAACCGAAAGTGAAGATGTGGTCCGGGGCCTGGAAGCCGGTGGCGTAGACTA
CATCACCAAACCAGTGCGGCCTAACGAACTGATCGCTCGCATCCGCGTACATTTAAACAATGCTCGCATGACGCAAAGCG
CCCACACCACCCTAGACCGACTTGGCCAAACCAGCTTTTCCACCGATGCGGCAGGCCAATGGCACTGGGCAACCCCACAC
ACCGACCAGCTACTGGAAAAAGCCAAGGTGGAACGCAGTGCGCTTGCAGACCCAATACAACGCTGGCTCAAACATCAACC
GGAGCGGGGCCAGCAACTCAATAAACTGCCCGGTAACCTAGGGCTACGTTATCTGGGCCATTCAGTGAGCGGTGAGGAAA
ATAGCGAGCACTTGTTCCGGCTGCTACACCACGACAGCGATGCAGAGCTGGAGTTGCTGAAAACTGCGCTGCATGTAACC
CACCGCGAGTCCCAGGTACTAGTGTGGATTGCACACGGTAAAACCAACCGAGAAATTGCCCAGATTCTTGAGTTAAGCCC
ACGGACAGTGAACAAACATCTGGAACAGATCTTCCGCAAACTGGGAGTTGAAAACCGGACTGCCGCAGCAGCCATGGTTA
TTCAATACCTTACCCAGATTCATTGA

Upstream 100 bases:

>100_bases
GAGAAAAGGGAAATCTGGGTTCTGATATAGCGGAAAAAATGCACACTTTACTTAAAATATTTGATTTTCAGGCCGTGATC
CGATTATTAGAGGCAGCCCC

Downstream 100 bases:

>100_bases
GCGCCAGTCACCACCTCAGGCAGTAACAGAACCACACCCGCATAACTGGCCACCAGCAAGGTCATGGCAACCCCCAGCCC
AAGGAAGGGCCCCACATTCA

Product: LuxR family DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTAAQRKDLILVVDDSPDSLGMIHQALDQAGLTALIALEGQQALNIAEKMTPDLILMDAIMPNLDGFETCRRLKQHPNLA
CVPVIFMTGLTESEDVVRGLEAGGVDYITKPVRPNELIARIRVHLNNARMTQSAHTTLDRLGQTSFSTDAAGQWHWATPH
TDQLLEKAKVERSALADPIQRWLKHQPERGQQLNKLPGNLGLRYLGHSVSGEENSEHLFRLLHHDSDAELELLKTALHVT
HRESQVLVWIAHGKTNREIAQILELSPRTVNKHLEQIFRKLGVENRTAAAAMVIQYLTQIH

Sequences:

>Translated_301_residues
MTAAQRKDLILVVDDSPDSLGMIHQALDQAGLTALIALEGQQALNIAEKMTPDLILMDAIMPNLDGFETCRRLKQHPNLA
CVPVIFMTGLTESEDVVRGLEAGGVDYITKPVRPNELIARIRVHLNNARMTQSAHTTLDRLGQTSFSTDAAGQWHWATPH
TDQLLEKAKVERSALADPIQRWLKHQPERGQQLNKLPGNLGLRYLGHSVSGEENSEHLFRLLHHDSDAELELLKTALHVT
HRESQVLVWIAHGKTNREIAQILELSPRTVNKHLEQIFRKLGVENRTAAAAMVIQYLTQIH
>Mature_300_residues
TAAQRKDLILVVDDSPDSLGMIHQALDQAGLTALIALEGQQALNIAEKMTPDLILMDAIMPNLDGFETCRRLKQHPNLAC
VPVIFMTGLTESEDVVRGLEAGGVDYITKPVRPNELIARIRVHLNNARMTQSAHTTLDRLGQTSFSTDAAGQWHWATPHT
DQLLEKAKVERSALADPIQRWLKHQPERGQQLNKLPGNLGLRYLGHSVSGEENSEHLFRLLHHDSDAELELLKTALHVTH
RESQVLVWIAHGKTNREIAQILELSPRTVNKHLEQIFRKLGVENRTAAAAMVIQYLTQIH

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=40.7079646017699, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790860, Length=156, Percent_Identity=32.6923076923077, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788394, Length=120, Percent_Identity=32.5, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=35.8974358974359, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789809, Length=116, Percent_Identity=35.3448275862069, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=32.7586206896552, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786911, Length=136, Percent_Identity=35.2941176470588, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787229, Length=113, Percent_Identity=30.9734513274336, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790863, Length=113, Percent_Identity=31.858407079646, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789149, Length=108, Percent_Identity=34.2592592592593, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 33700; Mature: 33569

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAQRKDLILVVDDSPDSLGMIHQALDQAGLTALIALEGQQALNIAEKMTPDLILMDAI
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCEEHHHH
MPNLDGFETCRRLKQHPNLACVPVIFMTGLTESEDVVRGLEAGGVDYITKPVRPNELIAR
CCCCCHHHHHHHHHHCCCCEEHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCCCHHHHHHH
IRVHLNNARMTQSAHTTLDRLGQTSFSTDAAGQWHWATPHTDQLLEKAKVERSALADPIQ
HHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
RWLKHQPERGQQLNKLPGNLGLRYLGHSVSGEENSEHLFRLLHHDSDAELELLKTALHVT
HHHHCCCCCCHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
HRESQVLVWIAHGKTNREIAQILELSPRTVNKHLEQIFRKLGVENRTAAAAMVIQYLTQI
CCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
H
C
>Mature Secondary Structure 
TAAQRKDLILVVDDSPDSLGMIHQALDQAGLTALIALEGQQALNIAEKMTPDLILMDAI
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCEEHHHH
MPNLDGFETCRRLKQHPNLACVPVIFMTGLTESEDVVRGLEAGGVDYITKPVRPNELIAR
CCCCCHHHHHHHHHHCCCCEEHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCCCHHHHHHH
IRVHLNNARMTQSAHTTLDRLGQTSFSTDAAGQWHWATPHTDQLLEKAKVERSALADPIQ
HHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
RWLKHQPERGQQLNKLPGNLGLRYLGHSVSGEENSEHLFRLLHHDSDAELELLKTALHVT
HHHHCCCCCCHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
HRESQVLVWIAHGKTNREIAQILELSPRTVNKHLEQIFRKLGVENRTAAAAMVIQYLTQI
CCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]