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The map label for this gene is coxB [H]

Identifier: 110834761

GI number: 110834761

Start: 2177648

End: 2178856

Strand: Reverse

Name: coxB [H]

Synonym: ABO_1900

Alternate gene names: 110834761

Gene position: 2178856-2177648 (Counterclockwise)

Preceding gene: 110834763

Following gene: 110834760

Centisome position: 69.83

GC content: 52.44

Gene sequence:

>1209_bases
ATGCAGTCAACTCTGTTCCACCGCGCAGCGGTTGGTCTTACGTCACTGATGATCAGTGGCATGACCTTCGCTAGCGACTG
GACCGAACGTTCCGATCTCGACCTGCGACCCGGGGTAACCCAGGCCAGCCAGGACGTTCAAGATCTTCACACCACCGTTC
TCTGGATCGTGACCGTTATCGGTCTTATGGTCTGTGGCCTGATTCTGTTCTCGATGATTCGCCACCGTCGATCCAAAAAC
CCAAATCCTTCCACTTTCCATGAAAACGTGTTTTTCGAAGTGCTGTGGACAGTGATTCCCTTTGTCATCCTGATTGCCAT
GGCCGTACCGGCCACCCGGGTGCTGGTTCAGCTGGATGACACCGCTGAATCTGAACTGACGGTGAAGGTAACCGGTTATC
GCTGGAAGTGGAGCTACGAGTATTTGACGTACGAAGATGACAACGATATCGGAGTCTCTTTCTTCTCTAACCTGGCTACG
CCGCCGGAACAGTACAACAACCCGGTTCTTTCCGGTGGCCTGTTTCCTTACGGCACAGCGAAGGAGCTGGTCGGTAAAGA
GGCTCCTGAGAAAGACCACAACTACAACTTGGAAGTGGATAACAAACTGCTTATCCCGTCTGGCCAAAAAGTGCGTTTCT
TGGTGACTTCTGATGACGTAATCCATTCTTTTTGGGTGCCGGACTTCGGCGGCAAGAAAGATGCAATTCCAGGTTTCGTT
AACGAGACCTGGGCTTTGGTTCCGGAAGGCAAAGAAGGCACTTACTACGGCCAGTGTGCTGAGTTGTGTGGTAAGAACCA
CGCCTTTATGCCGATTGCCGTAGAGGTAGTAACCCAGGACGAATTCAAGGCTTGGATTGCTGAAGAGAAAGAAAAAGCCG
CTTCTGGGCCCGACCTGACACCGTTTGCTGATATCGATCAGGCGATGGAAGAAGGTAAGCAAGTTTATGCTGGTGCCTGT
GCAATGTGTCACGGTGCTAATGGTGAAGGCGGTATCGGCTTGGCATTTGCTGGTACAGAGTTTGCCACCAATAACGAGCA
CCTGAACGAGCATATCGACGTGTTGGTGAATGGCCGTGCTGCCATGCCCAGCTTCAAGGCTCAACTGACACCTCGCCAGA
TTGCGGCGGTGATCACCTATGAGCGTAACGCTTTCGGCAACGATACCGGCGATCTGATTCAGCCCGCCGACGTTAACGAC
CACGAATAA

Upstream 100 bases:

>100_bases
CGCTGCATCAATCCTGAAACTCGCTTTCCAGGCGCCGGTAACGGCAAAGAACAAGCGTGCCTGTAATGGGGTAGCGCTGG
GGAAAACAGGGAGCAAACGC

Downstream 100 bases:

>100_bases
GGGAGGGGATAGCAATGTCTACTGCAGCTGCAACCCATGATGATCATCACGATCACCACCACGCCCCGACCGGCCTGAAA
CGTTGGCTGTTCAGCACCAA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MQSTLFHRAAVGLTSLMISGMTFASDWTERSDLDLRPGVTQASQDVQDLHTTVLWIVTVIGLMVCGLILFSMIRHRRSKN
PNPSTFHENVFFEVLWTVIPFVILIAMAVPATRVLVQLDDTAESELTVKVTGYRWKWSYEYLTYEDDNDIGVSFFSNLAT
PPEQYNNPVLSGGLFPYGTAKELVGKEAPEKDHNYNLEVDNKLLIPSGQKVRFLVTSDDVIHSFWVPDFGGKKDAIPGFV
NETWALVPEGKEGTYYGQCAELCGKNHAFMPIAVEVVTQDEFKAWIAEEKEKAASGPDLTPFADIDQAMEEGKQVYAGAC
AMCHGANGEGGIGLAFAGTEFATNNEHLNEHIDVLVNGRAAMPSFKAQLTPRQIAAVITYERNAFGNDTGDLIQPADVND
HE

Sequences:

>Translated_402_residues
MQSTLFHRAAVGLTSLMISGMTFASDWTERSDLDLRPGVTQASQDVQDLHTTVLWIVTVIGLMVCGLILFSMIRHRRSKN
PNPSTFHENVFFEVLWTVIPFVILIAMAVPATRVLVQLDDTAESELTVKVTGYRWKWSYEYLTYEDDNDIGVSFFSNLAT
PPEQYNNPVLSGGLFPYGTAKELVGKEAPEKDHNYNLEVDNKLLIPSGQKVRFLVTSDDVIHSFWVPDFGGKKDAIPGFV
NETWALVPEGKEGTYYGQCAELCGKNHAFMPIAVEVVTQDEFKAWIAEEKEKAASGPDLTPFADIDQAMEEGKQVYAGAC
AMCHGANGEGGIGLAFAGTEFATNNEHLNEHIDVLVNGRAAMPSFKAQLTPRQIAAVITYERNAFGNDTGDLIQPADVND
HE
>Mature_402_residues
MQSTLFHRAAVGLTSLMISGMTFASDWTERSDLDLRPGVTQASQDVQDLHTTVLWIVTVIGLMVCGLILFSMIRHRRSKN
PNPSTFHENVFFEVLWTVIPFVILIAMAVPATRVLVQLDDTAESELTVKVTGYRWKWSYEYLTYEDDNDIGVSFFSNLAT
PPEQYNNPVLSGGLFPYGTAKELVGKEAPEKDHNYNLEVDNKLLIPSGQKVRFLVTSDDVIHSFWVPDFGGKKDAIPGFV
NETWALVPEGKEGTYYGQCAELCGKNHAFMPIAVEVVTQDEFKAWIAEEKEKAASGPDLTPFADIDQAMEEGKQVYAGAC
AMCHGANGEGGIGLAFAGTEFATNNEHLNEHIDVLVNGRAAMPSFKAQLTPRQIAAVITYERNAFGNDTGDLIQPADVND
HE

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=192, Percent_Identity=35.4166666666667, Blast_Score=130, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6226540, Length=251, Percent_Identity=32.2709163346614, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 44389; Mature: 44389

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTLFHRAAVGLTSLMISGMTFASDWTERSDLDLRPGVTQASQDVQDLHTTVLWIVTVI
CCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GLMVCGLILFSMIRHRRSKNPNPSTFHENVFFEVLWTVIPFVILIAMAVPATRVLVQLDD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
TAESELTVKVTGYRWKWSYEYLTYEDDNDIGVSFFSNLATPPEQYNNPVLSGGLFPYGTA
CCCCEEEEEEEEEEEEEEEEEEEEECCCCCHHHHHHHCCCCHHHHCCCEEECCCCCCCCH
KELVGKEAPEKDHNYNLEVDNKLLIPSGQKVRFLVTSDDVIHSFWVPDFGGKKDAIPGFV
HHHHCCCCCCCCCCCCEEECCEEECCCCCEEEEEEECCCHHHEECCCCCCCCCCCCCCCC
NETWALVPEGKEGTYYGQCAELCGKNHAFMPIAVEVVTQDEFKAWIAEEKEKAASGPDLT
CCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCC
PFADIDQAMEEGKQVYAGACAMCHGANGEGGIGLAFAGTEFATNNEHLNEHIDVLVNGRA
CHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCCHHHHCCEEEEECCCC
AMPSFKAQLTPRQIAAVITYERNAFGNDTGDLIQPADVNDHE
CCCCHHHCCCHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQSTLFHRAAVGLTSLMISGMTFASDWTERSDLDLRPGVTQASQDVQDLHTTVLWIVTVI
CCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GLMVCGLILFSMIRHRRSKNPNPSTFHENVFFEVLWTVIPFVILIAMAVPATRVLVQLDD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
TAESELTVKVTGYRWKWSYEYLTYEDDNDIGVSFFSNLATPPEQYNNPVLSGGLFPYGTA
CCCCEEEEEEEEEEEEEEEEEEEEECCCCCHHHHHHHCCCCHHHHCCCEEECCCCCCCCH
KELVGKEAPEKDHNYNLEVDNKLLIPSGQKVRFLVTSDDVIHSFWVPDFGGKKDAIPGFV
HHHHCCCCCCCCCCCCEEECCEEECCCCCEEEEEEECCCHHHEECCCCCCCCCCCCCCCC
NETWALVPEGKEGTYYGQCAELCGKNHAFMPIAVEVVTQDEFKAWIAEEKEKAASGPDLT
CCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCC
PFADIDQAMEEGKQVYAGACAMCHGANGEGGIGLAFAGTEFATNNEHLNEHIDVLVNGRA
CHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCCHHHHCCEEEEECCCC
AMPSFKAQLTPRQIAAVITYERNAFGNDTGDLIQPADVNDHE
CCCCHHHCCCHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA