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The map label for this gene is fabG [H]

Identifier: 110834574

GI number: 110834574

Start: 1950119

End: 1951576

Strand: Direct

Name: fabG [H]

Synonym: ABO_1713

Alternate gene names: 110834574

Gene position: 1950119-1951576 (Clockwise)

Preceding gene: 110834567

Following gene: 110834575

Centisome position: 62.5

GC content: 56.04

Gene sequence:

>1458_bases
ATGAACACATTCATCATTCGATGGAAAAAGGACAGGACCATGAGCGATACCTATCAGACGATTGCCAACTCTCCCATGGG
CAAGGCGCTATTCGGTGCCATCAACTTGCCGATCCCGATTATTCTGGAGCGCTGGCAGCCGGGCCAGGCATCCTTTATCA
AAGGACGCGTGCTGGTAGGTGCCGCCCAGGGCTCCACAGCCATCGACAATGTACTGAAAACCCTTAAAGGTGCCCCCGAC
GCGCAGGTTGCCGTTCTTGCCAACACCGCCAACGCCACCGAATTGCAGAAGAAAGCCGGGAAGCTGGGTGTTGATGCGGG
CAACTACACTGCTAACCGTGAAGACAATGCTAAATTCAAAGGTCTGGTATTTGATGCCACCAGCATCCAGAGCCCAGATG
AGCTAAAAGCTCTGTGGGAGTTCTTCCACCCGGTGATCCGCAAGCTGGATAAATGCGCCCGCGTTGTCGTTATTGGTCGC
ACTCCAGAAAAACAGGCTGGCGCAGTGCGTGTTGCCCAGCGCGCCCTAGAAGGCTTCACTCGCTCCGTGGGCAAGGAAAT
CAAGAAAGGCGCCACTGCCCAGCTAATCTATGTAGATGAAGGCGCTGAGGCGCAGCTGGCGTCCCCACTGCATTTCTTCC
TATCACCCAAATCTGCTTATGTGTCCGGCCAGGTGGTGCGTGTTTCAGACGCAGGCTTCAAAGCCGCCAACTTCAACTGG
GACAAGCCATTGGCAGGCAAGAAAGCCTTGGTTACCGGTGGTTCCCGCGGTATTGGCGCCGCCATTGCTGAAGTTCTGTC
CCGCGACGGCGCTTCTGTCACCGTGCTGGACATCCCTCCCATGGCCGATGACCTAAATACGGTAGCCGCGCAGATCGGTG
GTGACACCCTTGAAATGGATATCACCGCTGACGAAGCCCCTGCAGCCATCGCCGCAAAAGCGAAGGCCATTGGCGGCTAT
GACGTGATTGTCCACAATGCCGGTGTAACCCGCGATAAAATGCTGGGCAACATGTCGGAAAAATTCTGGGACATGGTATT
GAACATCAATATTGCCAGCCAACTACGCATTAACGAGGCCCTGCTCTCCAGCGGCGGCTTGGGCAAAGGCGCCAGCATCA
TCTCCATCAGCTCCATCGCAGGCATTGCCGGCAACCTGGGCCAGACCAACTACGGCTGTTCCAAAGCAGCAGTAATTGGC
ATGGTCGATGCTTTTAAAGATGAGTACGCCGAGAAAGGCATCACCATCAATGCCGTGGCGCCGGGCTTCATCGAAACTCA
GATGACCGCCGCTATCCCCTTCACCATCCGTGAAGCAGGCCGTCGTATGAACGCCATGAACCAGGGCGGTCAGCCAGTAG
ATGTGGCAGAAACCATCGCCTTCTTTGCTAGCCCGGCATCTCAAGGCCTGACCGGCAACGTAGTACGTGTGTGTGGGCAG
ATGCTCTTGGGGGCGTAA

Upstream 100 bases:

>100_bases
GTGCGATAGGGGCAGATTTCCTGCCCTACGAAAGACGGCGTATTTTCACCCCGTCTTTGCGCGGCACCCCTTTAAACCCG
TTTCGTTTACCCTAAGGTAA

Downstream 100 bases:

>100_bases
ACGTCCGCGGTAGGCGACACGTTTCACGCAGCCCGTGTGACGCCGAGCCACATATCAACAAAAGAGCCGCGCCTTAGGGT
GCGGTTTTTTTGTGATTGAT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNTFIIRWKKDRTMSDTYQTIANSPMGKALFGAINLPIPIILERWQPGQASFIKGRVLVGAAQGSTAIDNVLKTLKGAPD
AQVAVLANTANATELQKKAGKLGVDAGNYTANREDNAKFKGLVFDATSIQSPDELKALWEFFHPVIRKLDKCARVVVIGR
TPEKQAGAVRVAQRALEGFTRSVGKEIKKGATAQLIYVDEGAEAQLASPLHFFLSPKSAYVSGQVVRVSDAGFKAANFNW
DKPLAGKKALVTGGSRGIGAAIAEVLSRDGASVTVLDIPPMADDLNTVAAQIGGDTLEMDITADEAPAAIAAKAKAIGGY
DVIVHNAGVTRDKMLGNMSEKFWDMVLNINIASQLRINEALLSSGGLGKGASIISISSIAGIAGNLGQTNYGCSKAAVIG
MVDAFKDEYAEKGITINAVAPGFIETQMTAAIPFTIREAGRRMNAMNQGGQPVDVAETIAFFASPASQGLTGNVVRVCGQ
MLLGA

Sequences:

>Translated_485_residues
MNTFIIRWKKDRTMSDTYQTIANSPMGKALFGAINLPIPIILERWQPGQASFIKGRVLVGAAQGSTAIDNVLKTLKGAPD
AQVAVLANTANATELQKKAGKLGVDAGNYTANREDNAKFKGLVFDATSIQSPDELKALWEFFHPVIRKLDKCARVVVIGR
TPEKQAGAVRVAQRALEGFTRSVGKEIKKGATAQLIYVDEGAEAQLASPLHFFLSPKSAYVSGQVVRVSDAGFKAANFNW
DKPLAGKKALVTGGSRGIGAAIAEVLSRDGASVTVLDIPPMADDLNTVAAQIGGDTLEMDITADEAPAAIAAKAKAIGGY
DVIVHNAGVTRDKMLGNMSEKFWDMVLNINIASQLRINEALLSSGGLGKGASIISISSIAGIAGNLGQTNYGCSKAAVIG
MVDAFKDEYAEKGITINAVAPGFIETQMTAAIPFTIREAGRRMNAMNQGGQPVDVAETIAFFASPASQGLTGNVVRVCGQ
MLLGA
>Mature_485_residues
MNTFIIRWKKDRTMSDTYQTIANSPMGKALFGAINLPIPIILERWQPGQASFIKGRVLVGAAQGSTAIDNVLKTLKGAPD
AQVAVLANTANATELQKKAGKLGVDAGNYTANREDNAKFKGLVFDATSIQSPDELKALWEFFHPVIRKLDKCARVVVIGR
TPEKQAGAVRVAQRALEGFTRSVGKEIKKGATAQLIYVDEGAEAQLASPLHFFLSPKSAYVSGQVVRVSDAGFKAANFNW
DKPLAGKKALVTGGSRGIGAAIAEVLSRDGASVTVLDIPPMADDLNTVAAQIGGDTLEMDITADEAPAAIAAKAKAIGGY
DVIVHNAGVTRDKMLGNMSEKFWDMVLNINIASQLRINEALLSSGGLGKGASIISISSIAGIAGNLGQTNYGCSKAAVIG
MVDAFKDEYAEKGITINAVAPGFIETQMTAAIPFTIREAGRRMNAMNQGGQPVDVAETIAFFASPASQGLTGNVVRVCGQ
MLLGA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=36.4341085271318, Blast_Score=129, Evalue=9e-30,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=30.241935483871, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=31.6872427983539, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=29.5546558704453, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4504505, Length=204, Percent_Identity=27.4509803921569, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=32.3232323232323, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=30.1075268817204, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=24.4, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI126723750, Length=272, Percent_Identity=26.1029411764706, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.1746031746032, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=29.6747967479675, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=35.6846473029046, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082100, Length=245, Percent_Identity=33.0612244897959, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=29.4354838709677, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=30.6122448979592, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789378, Length=275, Percent_Identity=30.9090909090909, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=29.4117647058824, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=33.0677290836653, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=32, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=26.0700389105058, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787526, Length=192, Percent_Identity=28.6458333333333, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=33.75, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=35.6846473029046, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.4516129032258, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=207, Percent_Identity=31.8840579710145, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=29.1497975708502, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=186, Percent_Identity=27.9569892473118, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=25.8823529411765, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=211, Percent_Identity=28.9099526066351, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=27.0916334661355, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=243, Percent_Identity=28.8065843621399, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=245, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=26.7676767676768, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=220, Percent_Identity=30.4545454545455, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=34.5381526104418, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI23397609, Length=238, Percent_Identity=33.6134453781513, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI17737361, Length=250, Percent_Identity=30.8, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357041, Length=241, Percent_Identity=30.7053941908714, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=28.8, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859837, Length=193, Percent_Identity=29.0155440414508, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=189, Percent_Identity=31.7460317460317, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571526, Length=242, Percent_Identity=31.404958677686, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640442, Length=201, Percent_Identity=31.3432835820896, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644339, Length=243, Percent_Identity=28.8065843621399, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 50997; Mature: 50997

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTFIIRWKKDRTMSDTYQTIANSPMGKALFGAINLPIPIILERWQPGQASFIKGRVLVG
CCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHCCCCHHHEEECCCCCCCCEEECEEEEE
AAQGSTAIDNVLKTLKGAPDAQVAVLANTANATELQKKAGKLGVDAGNYTANREDNAKFK
ECCCCHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
GLVFDATSIQSPDELKALWEFFHPVIRKLDKCARVVVIGRTPEKQAGAVRVAQRALEGFT
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHH
RSVGKEIKKGATAQLIYVDEGAEAQLASPLHFFLSPKSAYVSGQVVRVSDAGFKAANFNW
HHHHHHHHCCCCEEEEEEECCCCCHHCCCEEEEECCCCCEECCEEEEEECCCCEECCCCC
DKPLAGKKALVTGGSRGIGAAIAEVLSRDGASVTVLDIPPMADDLNTVAAQIGGDTLEMD
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEE
ITADEAPAAIAAKAKAIGGYDVIVHNAGVTRDKMLGNMSEKFWDMVLNINIASQLRINEA
EECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEHHHHHHHHH
LLSSGGLGKGASIISISSIAGIAGNLGQTNYGCSKAAVIGMVDAFKDEYAEKGITINAVA
HHCCCCCCCCCEEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECC
PGFIETQMTAAIPFTIREAGRRMNAMNQGGQPVDVAETIAFFASPASQGLTGNVVRVCGQ
CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
MLLGA
HHHCC
>Mature Secondary Structure
MNTFIIRWKKDRTMSDTYQTIANSPMGKALFGAINLPIPIILERWQPGQASFIKGRVLVG
CCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHCCCCHHHEEECCCCCCCCEEECEEEEE
AAQGSTAIDNVLKTLKGAPDAQVAVLANTANATELQKKAGKLGVDAGNYTANREDNAKFK
ECCCCHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
GLVFDATSIQSPDELKALWEFFHPVIRKLDKCARVVVIGRTPEKQAGAVRVAQRALEGFT
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHH
RSVGKEIKKGATAQLIYVDEGAEAQLASPLHFFLSPKSAYVSGQVVRVSDAGFKAANFNW
HHHHHHHHCCCCEEEEEEECCCCCHHCCCEEEEECCCCCEECCEEEEEECCCCEECCCCC
DKPLAGKKALVTGGSRGIGAAIAEVLSRDGASVTVLDIPPMADDLNTVAAQIGGDTLEMD
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEE
ITADEAPAAIAAKAKAIGGYDVIVHNAGVTRDKMLGNMSEKFWDMVLNINIASQLRINEA
EECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEHHHHHHHHH
LLSSGGLGKGASIISISSIAGIAGNLGQTNYGCSKAAVIGMVDAFKDEYAEKGITINAVA
HHCCCCCCCCCEEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECC
PGFIETQMTAAIPFTIREAGRRMNAMNQGGQPVDVAETIAFFASPASQGLTGNVVRVCGQ
CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
MLLGA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]