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The map label for this gene is nhaP [H]

Identifier: 110834265

GI number: 110834265

Start: 1600032

End: 1601990

Strand: Direct

Name: nhaP [H]

Synonym: ABO_1404

Alternate gene names: 110834265

Gene position: 1600032-1601990 (Clockwise)

Preceding gene: 110834263

Following gene: 110834272

Centisome position: 51.28

GC content: 53.19

Gene sequence:

>1959_bases
ATGGATTTAAGTGTCCCTTTCCAGCTAGCCATTATCACTGTGGTCGCTTTTCTCTGCCAATGGCTGTCTTGGAGAATCAA
ACTCCCTGCCATTTTGCCATTGCTGCTTACCGGTTTGGCGCTTGGCCCGCTTTGGGGTGTACTACAACCCAAAGAACTGT
TCGGTGATTTGCTACTTCCCGGTGTATCCCTGGCGGTCTCTATCATTCTGTTCGAAGGCGCCATGACACTGCGCTTCGAT
GAAATTCGCGGCTTGGAAAAAACCGTTCGCCGGCTTGTTACTTGGGGTGCCTTAGTCACCTGGAGCATTGTTACCGTCTC
TGCTTGGTGGGTGCTAAAACTCCCCTTGGGTCTAGCTTTACTTTTTGGTGCGCTGGTCGTGGTGACAGGCCCAACCGTTA
TTGTTCCTCTGCTACGCAGTGTCCGCCCAGTAAGCAGCGTATCTCGATTGCTGCGTTGGGAAGGCATCGTTATCGATCCC
TTGGGCGCTATTTTTGCTGTATTGGCCTACGAGTTGGTGGTGGCCAGCGGCCAAGATGGGGCCATACTGCACACGCTGTG
GCTGTTCTTCCAGACAATCGGCGTGGGAGCAGCCATCGGTTGTGCTGTGGCTTTCGGCTTGGCCGAGTTGTTGCGTCGGC
ATCTAATCCCTGAATACTTGCGCAGCTTTCTGGTGCTGTCGTCCATCATTGGTGAGTTTGTTTTAGCCAATGGCCTGAGT
GAGGAATCCGGACTGGTTGCGGTTACCGTAACCGGGATCGTGTTGGCTAACCGCAAAGGCGTGCGCACCGACGACATTCT
CCACTTCAAAGAAAACCTATCAGTGATGCTGATTTCCGGTCTCTTTATCGTGCTTGCCGCACGATTGGAAATGAGCGAAC
TCAGTCAACTCGGTGCTACCGCTCTGGCGGTTTTAGTGATTATTCAGTTCGTTGCTCGGCCATTGTCAGTATGGTTATCT
ACTCTTGGCTCCTCACTGAATTGGCGTGAAAAATCACTGCTCGCCTGGATTGCACCACGGGGCATTGTCGCCGCGGCGAT
CTCGGCCCTGTTCGCCGAACGGTTACAGCAAAACGGTGTTCCCGGTGCCGAGAAACTGGTGCCACTTACCTTCATGGTGA
TTATCGGCACGGTGGCATTACAGAGTCTCACCGCCCGTCCACTGGCTCGCCTGCTGAAAGTAGCAGAGCCGGCGCCACGC
GGTTTCCTGATTATCGGTGCTAACCCGGTGGCCCGTGCCATTGGCGCTGCCTTGCAGAAGAACCAATACCCGGTCGTGGT
CACGGATTCCAGTTGGGAATCCATCCGTTCTGCCCGTATGGAAGGACTAGGAACCTTTTATGGAAACCCGGTCTCACAGC
ACGCTGACCAATATTTGGATCTCGTTGGTTACGGAAAACTGCTGGGGTTAAGCCCTCGGCGAGAGCTCAACACTATGGCG
ACCATGCGCTACCGGCTGGAATTCGGAGAGCAAAACATCTTTAGCCTGCCCACGCAAAAAACGGAAAAGGAAGTGAAGCA
TGAGGTCGCCCCGGAGCACCGTGGTGCCACCCTCTTCGCTCCCGACATGACCTATGCCCGCCTAGCCAGCCTGCTCAGCC
AAGGCGCAGAAATTCGTAAAACGCGGCTGACTGAAGAATTTAGTTTTCAGGCTTACAACGAAACACCAGGACGCCAAGTT
TGGCCATTATTTGCCATTGATCCCCGCGAACATATTGTTGTGTTCTCTGCGGAAGAAAGCCCCGAGCCCAAAGCCGGCTG
GTACATTCTCGGGTTAGTAAAAGAAGATGCTGCCAAGGAAGAAAAAAAGGCTGAAGCTCGTGCAGAGGCGGCCGCCGAAA
AGGTAGCCACTGCAAATAAATCAGAGGACAAAAACGAGTCAAAAACCCATAAACGTGACGAAAAGACGGACACCAATAAG
GGTTCAAAACAAACGGCAGGCAAAACACAGCAAAATTGA

Upstream 100 bases:

>100_bases
ATCTCCAACCCCACTTTGCCATGAGCTACGTTAGCATGCCTGCCCGATGCTTAGTGGCGTGCACGAGGGTTGCGGAACCG
TCTAATCACCTAGGAACTTC

Downstream 100 bases:

>100_bases
CCTGTTGCCTCACTGCTAACTAAAGAGCCTGCCCAACTTTACTACGGGGCAGGCTTTTTAGTTGCTATCAGGGCTCGGCT
CTGAATCCTCATCCCCCACA

Product: NhaP-type Na+/H+ and K+/H+ antiporters

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MDLSVPFQLAIITVVAFLCQWLSWRIKLPAILPLLLTGLALGPLWGVLQPKELFGDLLLPGVSLAVSIILFEGAMTLRFD
EIRGLEKTVRRLVTWGALVTWSIVTVSAWWVLKLPLGLALLFGALVVVTGPTVIVPLLRSVRPVSSVSRLLRWEGIVIDP
LGAIFAVLAYELVVASGQDGAILHTLWLFFQTIGVGAAIGCAVAFGLAELLRRHLIPEYLRSFLVLSSIIGEFVLANGLS
EESGLVAVTVTGIVLANRKGVRTDDILHFKENLSVMLISGLFIVLAARLEMSELSQLGATALAVLVIIQFVARPLSVWLS
TLGSSLNWREKSLLAWIAPRGIVAAAISALFAERLQQNGVPGAEKLVPLTFMVIIGTVALQSLTARPLARLLKVAEPAPR
GFLIIGANPVARAIGAALQKNQYPVVVTDSSWESIRSARMEGLGTFYGNPVSQHADQYLDLVGYGKLLGLSPRRELNTMA
TMRYRLEFGEQNIFSLPTQKTEKEVKHEVAPEHRGATLFAPDMTYARLASLLSQGAEIRKTRLTEEFSFQAYNETPGRQV
WPLFAIDPREHIVVFSAEESPEPKAGWYILGLVKEDAAKEEKKAEARAEAAAEKVATANKSEDKNESKTHKRDEKTDTNK
GSKQTAGKTQQN

Sequences:

>Translated_652_residues
MDLSVPFQLAIITVVAFLCQWLSWRIKLPAILPLLLTGLALGPLWGVLQPKELFGDLLLPGVSLAVSIILFEGAMTLRFD
EIRGLEKTVRRLVTWGALVTWSIVTVSAWWVLKLPLGLALLFGALVVVTGPTVIVPLLRSVRPVSSVSRLLRWEGIVIDP
LGAIFAVLAYELVVASGQDGAILHTLWLFFQTIGVGAAIGCAVAFGLAELLRRHLIPEYLRSFLVLSSIIGEFVLANGLS
EESGLVAVTVTGIVLANRKGVRTDDILHFKENLSVMLISGLFIVLAARLEMSELSQLGATALAVLVIIQFVARPLSVWLS
TLGSSLNWREKSLLAWIAPRGIVAAAISALFAERLQQNGVPGAEKLVPLTFMVIIGTVALQSLTARPLARLLKVAEPAPR
GFLIIGANPVARAIGAALQKNQYPVVVTDSSWESIRSARMEGLGTFYGNPVSQHADQYLDLVGYGKLLGLSPRRELNTMA
TMRYRLEFGEQNIFSLPTQKTEKEVKHEVAPEHRGATLFAPDMTYARLASLLSQGAEIRKTRLTEEFSFQAYNETPGRQV
WPLFAIDPREHIVVFSAEESPEPKAGWYILGLVKEDAAKEEKKAEARAEAAAEKVATANKSEDKNESKTHKRDEKTDTNK
GSKQTAGKTQQN
>Mature_652_residues
MDLSVPFQLAIITVVAFLCQWLSWRIKLPAILPLLLTGLALGPLWGVLQPKELFGDLLLPGVSLAVSIILFEGAMTLRFD
EIRGLEKTVRRLVTWGALVTWSIVTVSAWWVLKLPLGLALLFGALVVVTGPTVIVPLLRSVRPVSSVSRLLRWEGIVIDP
LGAIFAVLAYELVVASGQDGAILHTLWLFFQTIGVGAAIGCAVAFGLAELLRRHLIPEYLRSFLVLSSIIGEFVLANGLS
EESGLVAVTVTGIVLANRKGVRTDDILHFKENLSVMLISGLFIVLAARLEMSELSQLGATALAVLVIIQFVARPLSVWLS
TLGSSLNWREKSLLAWIAPRGIVAAAISALFAERLQQNGVPGAEKLVPLTFMVIIGTVALQSLTARPLARLLKVAEPAPR
GFLIIGANPVARAIGAALQKNQYPVVVTDSSWESIRSARMEGLGTFYGNPVSQHADQYLDLVGYGKLLGLSPRRELNTMA
TMRYRLEFGEQNIFSLPTQKTEKEVKHEVAPEHRGATLFAPDMTYARLASLLSQGAEIRKTRLTEEFSFQAYNETPGRQV
WPLFAIDPREHIVVFSAEESPEPKAGWYILGLVKEDAAKEEKKAEARAEAAAEKVATANKSEDKNESKTHKRDEKTDTNK
GSKQTAGKTQQN

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=324, Percent_Identity=28.0864197530864, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 71196; Mature: 71196

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSVPFQLAIITVVAFLCQWLSWRIKLPAILPLLLTGLALGPLWGVLQPKELFGDLLLP
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GVSLAVSIILFEGAMTLRFDEIRGLEKTVRRLVTWGALVTWSIVTVSAWWVLKLPLGLAL
HHHHHHHHHHHHCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGALVVVTGPTVIVPLLRSVRPVSSVSRLLRWEGIVIDPLGAIFAVLAYELVVASGQDG
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCCCC
AILHTLWLFFQTIGVGAAIGCAVAFGLAELLRRHLIPEYLRSFLVLSSIIGEFVLANGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EESGLVAVTVTGIVLANRKGVRTDDILHFKENLSVMLISGLFIVLAARLEMSELSQLGAT
CCCCEEEEEEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHH
ALAVLVIIQFVARPLSVWLSTLGSSLNWREKSLLAWIAPRGIVAAAISALFAERLQQNGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
PGAEKLVPLTFMVIIGTVALQSLTARPLARLLKVAEPAPRGFLIIGANPVARAIGAALQK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHC
NQYPVVVTDSSWESIRSARMEGLGTFYGNPVSQHADQYLDLVGYGKLLGLSPRRELNTMA
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHCCCCHHHHHHHH
TMRYRLEFGEQNIFSLPTQKTEKEVKHEVAPEHRGATLFAPDMTYARLASLLSQGAEIRK
HHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHH
TRLTEEFSFQAYNETPGRQVWPLFAIDPREHIVVFSAEESPEPKAGWYILGLVKEDAAKE
HHHHHHHCCEECCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEEEEEEHHHHHHH
EKKAEARAEAAAEKVATANKSEDKNESKTHKRDEKTDTNKGSKQTAGKTQQN
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLSVPFQLAIITVVAFLCQWLSWRIKLPAILPLLLTGLALGPLWGVLQPKELFGDLLLP
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GVSLAVSIILFEGAMTLRFDEIRGLEKTVRRLVTWGALVTWSIVTVSAWWVLKLPLGLAL
HHHHHHHHHHHHCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGALVVVTGPTVIVPLLRSVRPVSSVSRLLRWEGIVIDPLGAIFAVLAYELVVASGQDG
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCCCC
AILHTLWLFFQTIGVGAAIGCAVAFGLAELLRRHLIPEYLRSFLVLSSIIGEFVLANGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EESGLVAVTVTGIVLANRKGVRTDDILHFKENLSVMLISGLFIVLAARLEMSELSQLGAT
CCCCEEEEEEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHH
ALAVLVIIQFVARPLSVWLSTLGSSLNWREKSLLAWIAPRGIVAAAISALFAERLQQNGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
PGAEKLVPLTFMVIIGTVALQSLTARPLARLLKVAEPAPRGFLIIGANPVARAIGAALQK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHC
NQYPVVVTDSSWESIRSARMEGLGTFYGNPVSQHADQYLDLVGYGKLLGLSPRRELNTMA
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHCCCCHHHHHHHH
TMRYRLEFGEQNIFSLPTQKTEKEVKHEVAPEHRGATLFAPDMTYARLASLLSQGAEIRK
HHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHH
TRLTEEFSFQAYNETPGRQVWPLFAIDPREHIVVFSAEESPEPKAGWYILGLVKEDAAKE
HHHHHHHCCEECCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEEEEEEHHHHHHH
EKKAEARAEAAAEKVATANKSEDKNESKTHKRDEKTDTNKGSKQTAGKTQQN
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA