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The map label for this gene is pgsA [H]

Identifier: 110834167

GI number: 110834167

Start: 1481051

End: 1481656

Strand: Direct

Name: pgsA [H]

Synonym: ABO_1306

Alternate gene names: 110834167

Gene position: 1481051-1481656 (Clockwise)

Preceding gene: 110834166

Following gene: 110834168

Centisome position: 47.47

GC content: 51.49

Gene sequence:

>606_bases
ATGCAGAAAGTGCACCCCATCCTGAATTTGCCGAATATCCTCACTCTGATTCGGGTATTGGCGATTCCCGTATTGGTGCT
GGTGTTCTATCTGCCGTTCCACTGGAGTGATGTTTGCGCGGCGTTATTGTTTCTGGCTGCGGGCATTACTGACTGGCTAG
ATGGCTATCTAGCGCGCAAGCTGAACCAAACCAGTCCTTTTGGGGCTTTTCTGGATCCAGTAGCTGACAAGTTAATTGTT
GCTGTGGCCTTGGTGATGTTGGTGCAAGTTCATGCTACTGCCTGGTTGGCCGTTCCTGCCATGGTGATTGTGTCTCGAGA
AATCACTGTCTCGGCATTGCGCGAGTGGATGGCAGAGCTTGGTCAGCGCGCAAAGGTGGCGGTGAGTCAGCTGGGCAAAA
TTAAAACGGTAACCCAAATGACGGCGATTACGTTGCTGCTGGCGCAAAAGCCGAAATTTACTTTAGACGGTGACATCATT
ATGAACCCGTGGCTTTGGTTGAGCTATGGGCTGCTGTACCTAGCAACGGCCTTCACCCTGTGGTCCATGGTGTCATATCT
GCGTGCTGCAGCCCCACAATTGCTCAAAAGTCAGTCAAAGTCCTGA

Upstream 100 bases:

>100_bases
GCTAGGAGGGGGCGTTTATTGATCTAAAAATCGGAAATGAGTCACGGCTGCCTTTGCGCTATACTGATAGCCTATTTCTT
CTAGTCGGTAGTCCCTCCCT

Downstream 100 bases:

>100_bases
AAAGTCAGAAAAAACACCTGATGCCGGGTTGACACCTGAAGGGGGGTGAGTAGAATTCACCCCCGCAACGGAGCGCGACT
CCGGTGTAGAAAAAGCGGGA

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltrans

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MQKVHPILNLPNILTLIRVLAIPVLVLVFYLPFHWSDVCAALLFLAAGITDWLDGYLARKLNQTSPFGAFLDPVADKLIV
AVALVMLVQVHATAWLAVPAMVIVSREITVSALREWMAELGQRAKVAVSQLGKIKTVTQMTAITLLLAQKPKFTLDGDII
MNPWLWLSYGLLYLATAFTLWSMVSYLRAAAPQLLKSQSKS

Sequences:

>Translated_201_residues
MQKVHPILNLPNILTLIRVLAIPVLVLVFYLPFHWSDVCAALLFLAAGITDWLDGYLARKLNQTSPFGAFLDPVADKLIV
AVALVMLVQVHATAWLAVPAMVIVSREITVSALREWMAELGQRAKVAVSQLGKIKTVTQMTAITLLLAQKPKFTLDGDII
MNPWLWLSYGLLYLATAFTLWSMVSYLRAAAPQLLKSQSKS
>Mature_201_residues
MQKVHPILNLPNILTLIRVLAIPVLVLVFYLPFHWSDVCAALLFLAAGITDWLDGYLARKLNQTSPFGAFLDPVADKLIV
AVALVMLVQVHATAWLAVPAMVIVSREITVSALREWMAELGQRAKVAVSQLGKIKTVTQMTAITLLLAQKPKFTLDGDII
MNPWLWLSYGLLYLATAFTLWSMVSYLRAAAPQLLKSQSKS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=192, Percent_Identity=49.4791666666667, Blast_Score=187, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22242; Mature: 22242

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVHPILNLPNILTLIRVLAIPVLVLVFYLPFHWSDVCAALLFLAAGITDWLDGYLARK
CCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LNQTSPFGAFLDPVADKLIVAVALVMLVQVHATAWLAVPAMVIVSREITVSALREWMAEL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQRAKVAVSQLGKIKTVTQMTAITLLLAQKPKFTLDGDIIMNPWLWLSYGLLYLATAFTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHH
WSMVSYLRAAAPQLLKSQSKS
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQKVHPILNLPNILTLIRVLAIPVLVLVFYLPFHWSDVCAALLFLAAGITDWLDGYLARK
CCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LNQTSPFGAFLDPVADKLIVAVALVMLVQVHATAWLAVPAMVIVSREITVSALREWMAEL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQRAKVAVSQLGKIKTVTQMTAITLLLAQKPKFTLDGDIIMNPWLWLSYGLLYLATAFTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHH
WSMVSYLRAAAPQLLKSQSKS
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075420 [H]