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The map label for this gene is choA [H]

Identifier: 110834120

GI number: 110834120

Start: 1433447

End: 1435015

Strand: Direct

Name: choA [H]

Synonym: ABO_1259

Alternate gene names: 110834120

Gene position: 1433447-1435015 (Clockwise)

Preceding gene: 110834117

Following gene: 110834121

Centisome position: 45.94

GC content: 55.13

Gene sequence:

>1569_bases
ATGGAAAACGTGGATGTGCTGGTCATCGGCAGTGGTTTCGGGGGCGCTGTAATGGCATGTCGGTTAGCAGAGAAGGGCCG
TAAGGTTGTCGTGCTGGAGCGGGGACGACGCTGGCTGCCTAGTGATTACCCCTCTGTTTCACAGAAAAACTGGTTCTGGG
ATGAAGCGGAACCGGAAAAACAAAATGGATGGGTCGATTTCCGCAATTTCGGCGATATGAGCATTGCCATGGGCGCAGGC
GTTGGCGGTGGGTCGTTGATCTATGCCAATGTAAGCATTGAGGCTAAACCAGAAGCGTTCGACCACGGTTGGCCGCAAGC
GATTAATTATTCCACCTTGAAGCCTTACTATGACATCACTGGAGTGATGCTCAATGTTCAGACCTTGCCCGCCAGCCAGT
GGACGCCCCGAACCCATTTGATGAAAGAGGCGGCAGATGCGGTAGGTGCGGGGGATCGATTCACGGTGCTGCCCCAGGCA
ATTACATTCGATCCGGATTGGCGAGCGGAAAACGACGACTGTTTCGATTATCGCCACAGTAAGATGTGGGTAAATGCCCA
GGGAAAGCAGCAGGGTACTTGCACCCATTGTGGCAATTGTGATTTGGGGTGTCCGGTTAAGGCCAAAAACACCTTGGATC
TTAATTATCTGGCAGCGGCAGAAAGCGCTGGTGCGCAGATCCGTCCATTGCATCACGTGCGTACCATTCGCCCGCTGGCG
TCAGGAGGTTTTGAGGTGCGCGCCATGGATCTGGACGCGCGTGGCTGGCGAGTCTTTAAGGCCAATAAAGTGATTGTGGC
CGCTGGCTCCCTGGGCTCCACTGAACTGTTGCTGCGTTGTCGAGATCAATACAAAACGCTACCAAAGTTAAGCCGTAAAC
TGGGGCATAACTGGAGCAGTAACGGCGACTTTGCCACGGCGGCGTTCTACGATGATCGACAGATTTCACCCACCCGGGGG
CCAACCATCACCAGTGCTATCGATTACTTGGATGGATCTGATAACGGTGCCCGTTATTTTGTAGAAGACGGCGGTCTTCC
GGATATTCTTGGAAGCTGGCTGGAGCGATTGGGCAAACAGCCTCGCTTTAGTAGCACACGGTTAGGAGCCGCGATGCTCA
AGTATGGCGATAGCAGTAACCCCTTTGGGAAAATGATGCCCTGGTTTGGTCAGGCCATGGATGAACCGGGCGGTACTTTT
TCCTTGGCGCGGCGTTGGTATTGGCCCTGGAAGCGTGAGCACCTGAAACTGCGTTGGGACTACCGCAAGGCAGAAAAAGC
CGTGCAAGGCCTGGCCGATCGCCATTTAGCGCTAACGGCGGCCACTGGCGGTAGCCCGATGGCTCCAGTCACCTGGAGCT
GGTTCAAGAATTTGGTTACCCCGCACCCTCTGGGCGGCTGCAATATGGCGGACTCTGTGGAACAGGGGGTGGTGAATCAT
GCCGGGGAAGTGTTCAATTACCCTGATCTTTATGTGATAGATGGCGCCATGGTGCCGCGGGCACTGGGCTTAAACCCGTC
CCGGACCATCGCAGCACTGGCGGAATATTGTGCGGCTCAGATGGACTAA

Upstream 100 bases:

>100_bases
GACCACGGGGCCTCTGCAAAACACGATGCATGCTAAGCATGGCAGAGATCTTGTAATGGGGGCAGAGGGCAGGTTCAAAA
AATAAAACACTGGGGACAAC

Downstream 100 bases:

>100_bases
ATTCCCAGAGAGGAGTAACGCAGAAGCATGAGTGATGCCCGTTTCCATATCGTGTTTTCCGGGAAGTTGGTCGGCGGCGC
CGATTTATCCACGGTGAAGA

Product: cholesterol oxidase

Products: NA

Alternate protein names: CHOD [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MENVDVLVIGSGFGGAVMACRLAEKGRKVVVLERGRRWLPSDYPSVSQKNWFWDEAEPEKQNGWVDFRNFGDMSIAMGAG
VGGGSLIYANVSIEAKPEAFDHGWPQAINYSTLKPYYDITGVMLNVQTLPASQWTPRTHLMKEAADAVGAGDRFTVLPQA
ITFDPDWRAENDDCFDYRHSKMWVNAQGKQQGTCTHCGNCDLGCPVKAKNTLDLNYLAAAESAGAQIRPLHHVRTIRPLA
SGGFEVRAMDLDARGWRVFKANKVIVAAGSLGSTELLLRCRDQYKTLPKLSRKLGHNWSSNGDFATAAFYDDRQISPTRG
PTITSAIDYLDGSDNGARYFVEDGGLPDILGSWLERLGKQPRFSSTRLGAAMLKYGDSSNPFGKMMPWFGQAMDEPGGTF
SLARRWYWPWKREHLKLRWDYRKAEKAVQGLADRHLALTAATGGSPMAPVTWSWFKNLVTPHPLGGCNMADSVEQGVVNH
AGEVFNYPDLYVIDGAMVPRALGLNPSRTIAALAEYCAAQMD

Sequences:

>Translated_522_residues
MENVDVLVIGSGFGGAVMACRLAEKGRKVVVLERGRRWLPSDYPSVSQKNWFWDEAEPEKQNGWVDFRNFGDMSIAMGAG
VGGGSLIYANVSIEAKPEAFDHGWPQAINYSTLKPYYDITGVMLNVQTLPASQWTPRTHLMKEAADAVGAGDRFTVLPQA
ITFDPDWRAENDDCFDYRHSKMWVNAQGKQQGTCTHCGNCDLGCPVKAKNTLDLNYLAAAESAGAQIRPLHHVRTIRPLA
SGGFEVRAMDLDARGWRVFKANKVIVAAGSLGSTELLLRCRDQYKTLPKLSRKLGHNWSSNGDFATAAFYDDRQISPTRG
PTITSAIDYLDGSDNGARYFVEDGGLPDILGSWLERLGKQPRFSSTRLGAAMLKYGDSSNPFGKMMPWFGQAMDEPGGTF
SLARRWYWPWKREHLKLRWDYRKAEKAVQGLADRHLALTAATGGSPMAPVTWSWFKNLVTPHPLGGCNMADSVEQGVVNH
AGEVFNYPDLYVIDGAMVPRALGLNPSRTIAALAEYCAAQMD
>Mature_522_residues
MENVDVLVIGSGFGGAVMACRLAEKGRKVVVLERGRRWLPSDYPSVSQKNWFWDEAEPEKQNGWVDFRNFGDMSIAMGAG
VGGGSLIYANVSIEAKPEAFDHGWPQAINYSTLKPYYDITGVMLNVQTLPASQWTPRTHLMKEAADAVGAGDRFTVLPQA
ITFDPDWRAENDDCFDYRHSKMWVNAQGKQQGTCTHCGNCDLGCPVKAKNTLDLNYLAAAESAGAQIRPLHHVRTIRPLA
SGGFEVRAMDLDARGWRVFKANKVIVAAGSLGSTELLLRCRDQYKTLPKLSRKLGHNWSSNGDFATAAFYDDRQISPTRG
PTITSAIDYLDGSDNGARYFVEDGGLPDILGSWLERLGKQPRFSSTRLGAAMLKYGDSSNPFGKMMPWFGQAMDEPGGTF
SLARRWYWPWKREHLKLRWDYRKAEKAVQGLADRHLALTAATGGSPMAPVTWSWFKNLVTPHPLGGCNMADSVEQGVVNH
AGEVFNYPDLYVIDGAMVPRALGLNPSRTIAALAEYCAAQMD

Specific function: Unknown

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867
- InterPro:   IPR006311 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.3.6 [H]

Molecular weight: Translated: 57658; Mature: 57658

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVDVLVIGSGFGGAVMACRLAEKGRKVVVLERGRRWLPSDYPSVSQKNWFWDEAEPEK
CCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
QNGWVDFRNFGDMSIAMGAGVGGGSLIYANVSIEAKPEAFDHGWPQAINYSTLKPYYDIT
CCCCEEECCCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEE
GVMLNVQTLPASQWTPRTHLMKEAADAVGAGDRFTVLPQAITFDPDWRAENDDCFDYRHS
EEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEECCCCCCCCCCCHHCCCCC
KMWVNAQGKQQGTCTHCGNCDLGCPVKAKNTLDLNYLAAAESAGAQIRPLHHVRTIRPLA
EEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHH
SGGFEVRAMDLDARGWRVFKANKVIVAAGSLGSTELLLRCRDQYKTLPKLSRKLGHNWSS
CCCEEEEEEEECCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
NGDFATAAFYDDRQISPTRGPTITSAIDYLDGSDNGARYFVEDGGLPDILGSWLERLGKQ
CCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCC
PRFSSTRLGAAMLKYGDSSNPFGKMMPWFGQAMDEPGGTFSLARRWYWPWKREHLKLRWD
CCCCCHHHHHHHHHCCCCCCCHHHHCHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEEEEC
YRKAEKAVQGLADRHLALTAATGGSPMAPVTWSWFKNLVTPHPLGGCNMADSVEQGVVNH
HHHHHHHHHHHHCCEEEEEEECCCCCCCCEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AGEVFNYPDLYVIDGAMVPRALGLNPSRTIAALAEYCAAQMD
CHHHCCCCCEEEECCCCCCHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENVDVLVIGSGFGGAVMACRLAEKGRKVVVLERGRRWLPSDYPSVSQKNWFWDEAEPEK
CCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
QNGWVDFRNFGDMSIAMGAGVGGGSLIYANVSIEAKPEAFDHGWPQAINYSTLKPYYDIT
CCCCEEECCCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEE
GVMLNVQTLPASQWTPRTHLMKEAADAVGAGDRFTVLPQAITFDPDWRAENDDCFDYRHS
EEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEECCCCCCCCCCCHHCCCCC
KMWVNAQGKQQGTCTHCGNCDLGCPVKAKNTLDLNYLAAAESAGAQIRPLHHVRTIRPLA
EEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHH
SGGFEVRAMDLDARGWRVFKANKVIVAAGSLGSTELLLRCRDQYKTLPKLSRKLGHNWSS
CCCEEEEEEEECCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
NGDFATAAFYDDRQISPTRGPTITSAIDYLDGSDNGARYFVEDGGLPDILGSWLERLGKQ
CCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCC
PRFSSTRLGAAMLKYGDSSNPFGKMMPWFGQAMDEPGGTFSLARRWYWPWKREHLKLRWD
CCCCCHHHHHHHHHCCCCCCCHHHHCHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEEEEC
YRKAEKAVQGLADRHLALTAATGGSPMAPVTWSWFKNLVTPHPLGGCNMADSVEQGVVNH
HHHHHHHHHHHHCCEEEEEEECCCCCCCCEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AGEVFNYPDLYVIDGAMVPRALGLNPSRTIAALAEYCAAQMD
CHHHCCCCCEEEECCCCCCHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2914858; 10194345 [H]