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The map label for this gene is accA

Identifier: 110834020

GI number: 110834020

Start: 1318963

End: 1319934

Strand: Direct

Name: accA

Synonym: ABO_1159

Alternate gene names: 110834020

Gene position: 1318963-1319934 (Clockwise)

Preceding gene: 110834019

Following gene: 110834021

Centisome position: 42.27

GC content: 52.26

Gene sequence:

>972_bases
ATGAATCCCAATTTCCTCGAATTTGAACAACCGATTGCCGACCTGGAAGCGAAAATCGAGGAACTGCGTTTGGTGGGCAG
TGGCAGTGATATAAACATTTCCGAGGAAGTGGCCAAGTTGCAGGAAAAGAGTATCACGCTTACCGAGAGCATTTTCCGAG
GGCTAAGCTCCTGGCAAATTTCCCAACTTTCCCGTCATCCTAAACGCCCCTATATGTTGGATTACATCAAGCGGATCTTT
ACCGACTTTGATGAATTGCATGGTGACCGTGCCTTTTCTGATGATCCTGCGATTATTGGGGGCATGACCCGATTGAACGG
GCAGCCAGTGATGGTGATTGGCCATCAAAAAGGCCGCGAAGTGAAAGAAAAGGTTCGTCGCAATTTCGGCATGCCGAAAC
CGGAAGGTTACCGTAAGGCGCTGCGATTGATGGAAATGGCTGAACGGTTCAAGTTGCCGGTGCTGACGTTCATTGATACG
CCTGGGGCGTTTCCGGGGATTGATGCGGAAGAGCGCGGTCAGTCCGAAGCCATTGCCCGTAATTTGCGTGTAATGTCCCA
GCTCAAAACTCCCATTCTCGCCACTGTTATTGGTGAAGGGGGGTCCGGTGGGGCGCTGGCGATTGGTGTGTGTGACCATT
TACAGATGCTGGAATTTTCTACCTATTCGGTTATTTCTCCAGAAGGGTGCGCCTCCATTCTTTGGCGCAGTGCGGATAAA
GCCCCTGAAGCTGCGCAAGCCATGGGCCTAACTGCCGGGCGATTACATGAGCTCGGCATCGTTGACCAAGTGATCAAGGA
GCCTCTGGGAGGCGCTCACCGGGATTATGACCAAGCTGCCGATGCGATTCGCAAGGCATTGGCAGCACAATTAGAATCGC
TTTGTTCCATGGAGACTGACGCCCTCATTAACCGCCGTTACGAACGTTTGATGAGTTACGGCAACGTGGTTAGCGACCCC
GCCGACGAATAG

Upstream 100 bases:

>100_bases
GCGTTTGGCGCTCCAGCGTGACGTTTCTGCCATATTAACGCCATAGAGAGGCCATTCTGGCCCGGGCGCATGCTGATAAC
ATCTTGGACAGGCAAAGAAT

Downstream 100 bases:

>100_bases
TCATGTCTGATGCTGCTAGGTTCAGCCAGCGCTTGGTTGAACAGGCCCCAGACGGGCCACTGTTGCTTGCCTTAAGCGGT
GGCCTCGATTCCTCTCTATT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MNPNFLEFEQPIADLEAKIEELRLVGSGSDINISEEVAKLQEKSITLTESIFRGLSSWQISQLSRHPKRPYMLDYIKRIF
TDFDELHGDRAFSDDPAIIGGMTRLNGQPVMVIGHQKGREVKEKVRRNFGMPKPEGYRKALRLMEMAERFKLPVLTFIDT
PGAFPGIDAEERGQSEAIARNLRVMSQLKTPILATVIGEGGSGGALAIGVCDHLQMLEFSTYSVISPEGCASILWRSADK
APEAAQAMGLTAGRLHELGIVDQVIKEPLGGAHRDYDQAADAIRKALAAQLESLCSMETDALINRRYERLMSYGNVVSDP
ADE

Sequences:

>Translated_323_residues
MNPNFLEFEQPIADLEAKIEELRLVGSGSDINISEEVAKLQEKSITLTESIFRGLSSWQISQLSRHPKRPYMLDYIKRIF
TDFDELHGDRAFSDDPAIIGGMTRLNGQPVMVIGHQKGREVKEKVRRNFGMPKPEGYRKALRLMEMAERFKLPVLTFIDT
PGAFPGIDAEERGQSEAIARNLRVMSQLKTPILATVIGEGGSGGALAIGVCDHLQMLEFSTYSVISPEGCASILWRSADK
APEAAQAMGLTAGRLHELGIVDQVIKEPLGGAHRDYDQAADAIRKALAAQLESLCSMETDALINRRYERLMSYGNVVSDP
ADE
>Mature_323_residues
MNPNFLEFEQPIADLEAKIEELRLVGSGSDINISEEVAKLQEKSITLTESIFRGLSSWQISQLSRHPKRPYMLDYIKRIF
TDFDELHGDRAFSDDPAIIGGMTRLNGQPVMVIGHQKGREVKEKVRRNFGMPKPEGYRKALRLMEMAERFKLPVLTFIDT
PGAFPGIDAEERGQSEAIARNLRVMSQLKTPILATVIGEGGSGGALAIGVCDHLQMLEFSTYSVISPEGCASILWRSADK
APEAAQAMGLTAGRLHELGIVDQVIKEPLGGAHRDYDQAADAIRKALAAQLESLCSMETDALINRRYERLMSYGNVVSDP
ADE

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=66.5615141955836, Blast_Score=443, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_ALCBS (Q0VQE1)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692879.1
- ProteinModelPortal:   Q0VQE1
- SMR:   Q0VQE1
- STRING:   Q0VQE1
- GeneID:   4211797
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1159
- NMPDR:   fig|393595.12.peg.1170
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q0VQE1
- ProtClustDB:   PRK05724
- BioCyc:   ABOR393595:ABO_1159-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35719; Mature: 35719

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNFLEFEQPIADLEAKIEELRLVGSGSDINISEEVAKLQEKSITLTESIFRGLSSWQI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH
SQLSRHPKRPYMLDYIKRIFTDFDELHGDRAFSDDPAIIGGMTRLNGQPVMVIGHQKGRE
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHCCCCEEEEEECCCCHH
VKEKVRRNFGMPKPEGYRKALRLMEMAERFKLPVLTFIDTPGAFPGIDAEERGQSEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHCCHHHHHHH
NLRVMSQLKTPILATVIGEGGSGGALAIGVCDHLQMLEFSTYSVISPEGCASILWRSADK
HHHHHHHHCCHHEEHHCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
APEAAQAMGLTAGRLHELGIVDQVIKEPLGGAHRDYDQAADAIRKALAAQLESLCSMETD
CHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALINRRYERLMSYGNVVSDPADE
HHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNPNFLEFEQPIADLEAKIEELRLVGSGSDINISEEVAKLQEKSITLTESIFRGLSSWQI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH
SQLSRHPKRPYMLDYIKRIFTDFDELHGDRAFSDDPAIIGGMTRLNGQPVMVIGHQKGRE
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHCCCCEEEEEECCCCHH
VKEKVRRNFGMPKPEGYRKALRLMEMAERFKLPVLTFIDTPGAFPGIDAEERGQSEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHCCHHHHHHH
NLRVMSQLKTPILATVIGEGGSGGALAIGVCDHLQMLEFSTYSVISPEGCASILWRSADK
HHHHHHHHCCHHEEHHCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
APEAAQAMGLTAGRLHELGIVDQVIKEPLGGAHRDYDQAADAIRKALAAQLESLCSMETD
CHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALINRRYERLMSYGNVVSDPADE
HHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA