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The map label for this gene is frr

Identifier: 110834007

GI number: 110834007

Start: 1303357

End: 1303914

Strand: Direct

Name: frr

Synonym: ABO_1146

Alternate gene names: 110834007

Gene position: 1303357-1303914 (Clockwise)

Preceding gene: 110834006

Following gene: 110834008

Centisome position: 41.77

GC content: 49.64

Gene sequence:

>558_bases
GTGATTGACGATATTCGCAGTGATGCGCAAAGCCGCATGAAAAAGAGTCTTGAAGCGCTGGATACAGCCATGAAACGGGT
GCGTACAGGTCGTGCCCATCCTAGCTTGCTGGACAATATTACCATTGAGTACTACGGTGCCGAGACGCCCCTGAATCAGA
TGGGGAATATCTCGGTGGAAGAAGGGAGAACGCTGACTATTTCGCCGTTTGATAAGTCCCTGATTCCACAAATTGAGCGT
GCCATTTTAATGTCTGATCTGGGCCTTAATCCGTCCACCTCGGGCACTCTTATTCGTTTGCCATTGCCGCCGTTGACTGA
GGAAACCCGCCGTGACCTAGTCAAGGTGGTGCGTGCGGAAGCGGAGCAGGCACGTGTGTCCATTCGTAATATTCGTCGTG
ATGCTAATAGCGATTTGAAAGAATTGCTTAAGGAAAAAGAAATTTCCGAAGACGAGCAGCGCCGTGGGGAAGAGCAAATT
CAGCAGCTCACCGACAAAATGGTGGCGGAAGTGGAAGGTGTTCTGAAAGAGAAAGAAGAAGAATTGATGACCGTTTGA

Upstream 100 bases:

>100_bases
GGTGCCTTGCTTAATCTGATGCTGGGCGGTAAGGAAGGCACTCTGGTAGAGGCCGCACAATAAGTGCAGCTGATACGCTG
AATAGAAGCGAGGAAAAACG

Downstream 100 bases:

>100_bases
TCGCTTCGCGCGAGCGGTGATCGAAAGACATCTCGGGCTGCAGGTCAGCCCGTTTCTATTCTTGGCGGATGCAGTATGGC
CGACAATCAGCCTCATTCCA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIDDIRSDAQSRMKKSLEALDTAMKRVRTGRAHPSLLDNITIEYYGAETPLNQMGNISVEEGRTLTISPFDKSLIPQIER
AILMSDLGLNPSTSGTLIRLPLPPLTEETRRDLVKVVRAEAEQARVSIRNIRRDANSDLKELLKEKEISEDEQRRGEEQI
QQLTDKMVAEVEGVLKEKEEELMTV

Sequences:

>Translated_185_residues
MIDDIRSDAQSRMKKSLEALDTAMKRVRTGRAHPSLLDNITIEYYGAETPLNQMGNISVEEGRTLTISPFDKSLIPQIER
AILMSDLGLNPSTSGTLIRLPLPPLTEETRRDLVKVVRAEAEQARVSIRNIRRDANSDLKELLKEKEISEDEQRRGEEQI
QQLTDKMVAEVEGVLKEKEEELMTV
>Mature_185_residues
MIDDIRSDAQSRMKKSLEALDTAMKRVRTGRAHPSLLDNITIEYYGAETPLNQMGNISVEEGRTLTISPFDKSLIPQIER
AILMSDLGLNPSTSGTLIRLPLPPLTEETRRDLVKVVRAEAEQARVSIRNIRRDANSDLKELLKEKEISEDEQRRGEEQI
QQLTDKMVAEVEGVLKEKEEELMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=173, Percent_Identity=33.5260115606936, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI291042689, Length=149, Percent_Identity=34.2281879194631, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=57.9234972677596, Blast_Score=232, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24661488, Length=175, Percent_Identity=26.8571428571429, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_ALCBS (Q0VQF4)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692866.1
- ProteinModelPortal:   Q0VQF4
- SMR:   Q0VQF4
- STRING:   Q0VQF4
- GeneID:   4211551
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1146
- NMPDR:   fig|393595.12.peg.1157
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q0VQF4
- ProtClustDB:   PRK00083
- BioCyc:   ABOR393595:ABO_1146-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20985; Mature: 20985

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDIRSDAQSRMKKSLEALDTAMKRVRTGRAHPSLLDNITIEYYGAETPLNQMGNISVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCEEEEECCCCCHHHHCCCEEC
EGRTLTISPFDKSLIPQIERAILMSDLGLNPSTSGTLIRLPLPPLTEETRRDLVKVVRAE
CCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AEQARVSIRNIRRDANSDLKELLKEKEISEDEQRRGEEQIQQLTDKMVAEVEGVLKEKEE
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMTV
HHCCC
>Mature Secondary Structure
MIDDIRSDAQSRMKKSLEALDTAMKRVRTGRAHPSLLDNITIEYYGAETPLNQMGNISVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCEEEEECCCCCHHHHCCCEEC
EGRTLTISPFDKSLIPQIERAILMSDLGLNPSTSGTLIRLPLPPLTEETRRDLVKVVRAE
CCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AEQARVSIRNIRRDANSDLKELLKEKEISEDEQRRGEEQIQQLTDKMVAEVEGVLKEKEE
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMTV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA