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The map label for this gene is etfA [H]

Identifier: 110833963

GI number: 110833963

Start: 1251555

End: 1252484

Strand: Direct

Name: etfA [H]

Synonym: ABO_1102

Alternate gene names: 110833963

Gene position: 1251555-1252484 (Clockwise)

Preceding gene: 110833962

Following gene: 110833964

Centisome position: 40.11

GC content: 54.62

Gene sequence:

>930_bases
ATGAGTGTATTAGTTTACGCCGAACACGATAACGCCGCGCTCAACAAGGTCACCCTGAGTGTGGTTGCTGCTGCTAAAGA
AATTGGCGGCGACATCACTGTGCTGGTAGCTGGTAAAGGCTGTGGCCCTGTTGCTGAGGAAGCCGCTAAAATTGATGGCG
TTTCCAAAGTGCTGTGCGCAGACAACGATGCCTACGAGCATCAGCTGGCTGAAAACATTGGCGATCTGGTTGCTGAAGTT
GCTGGCGATTACAGCCACATCTTGGCTGCTGCCACTACCACCGGTAAGAACTTCGCGCCTCGCGCGGCGGCTTTGCTGGA
CGTGGCTCAGATCTCTGAGATTTCCGACGTGATCGATGCGGATACTTTCAAGCGTCCGATCTACGCTGGTAACGCCATTG
CGACCGTTAAATGTGGCGATGCCAAGAAAGTGATCACCGTGCGTGGTACTTCTTTCGATGGCGTTGCAGCAGAAGGCGGT
TCTGCTTCTGTTGAGAACATCGACGTTGCTAAAGACGCTGGCATTTCTTCCTTCGTGGGTGAAGAGCTGGCCAAGTCTGA
TCGTCCTGAGCTGACCTCTGCCGAGATCGTAATCTCCGGTGGTCGTGGCATGGGTAACGGCGAAAACTTCGAAATTCTGT
ACAAGCTGGCTGATAAGCTGGGCGCTGGCGTGGGTGCATCCCGTGCCGCCGTTGACGCAGGTTTCGTTCCTAACGACATG
CAGGTCGGTCAGACCGGTAAAATCGTTGCGCCGAACCTGTACGTTGCTGTGGGCATCTCCGGTGCCATCCAGCATTTGGC
CGGTATGAAAGACTCTAAGGTCATCGTTGCTATTAACAAGGACGAAGAAGCCCCCATCTTCCAGGTGGCGGACTACGGCC
TAGTGGCTGACCTGTTCGAAGCAGTACCGGAGCTGGACGGCAAGCTGTAA

Upstream 100 bases:

>100_bases
CTGAAAAAGTGGAAGCTCCGGCTGAGCGTCAGGCTGGCATTATCGTTGGCTCCGTTGACGAGCTGGTCGAGAAACTGAAG
AACGAAGCGAAGGTGATCTG

Downstream 100 bases:

>100_bases
AGCGCGCCTTCCGCACCAAAAAAAACCCGGCCTTGTGCCGGGTTTTTTGTTTTTGACGTTGGGCAAAATACAATCGTGGC
TATTGGATCCAAAAGTGTGA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSVLVYAEHDNAALNKVTLSVVAAAKEIGGDITVLVAGKGCGPVAEEAAKIDGVSKVLCADNDAYEHQLAENIGDLVAEV
AGDYSHILAAATTTGKNFAPRAAALLDVAQISEISDVIDADTFKRPIYAGNAIATVKCGDAKKVITVRGTSFDGVAAEGG
SASVENIDVAKDAGISSFVGEELAKSDRPELTSAEIVISGGRGMGNGENFEILYKLADKLGAGVGASRAAVDAGFVPNDM
QVGQTGKIVAPNLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAVPELDGKL

Sequences:

>Translated_309_residues
MSVLVYAEHDNAALNKVTLSVVAAAKEIGGDITVLVAGKGCGPVAEEAAKIDGVSKVLCADNDAYEHQLAENIGDLVAEV
AGDYSHILAAATTTGKNFAPRAAALLDVAQISEISDVIDADTFKRPIYAGNAIATVKCGDAKKVITVRGTSFDGVAAEGG
SASVENIDVAKDAGISSFVGEELAKSDRPELTSAEIVISGGRGMGNGENFEILYKLADKLGAGVGASRAAVDAGFVPNDM
QVGQTGKIVAPNLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAVPELDGKL
>Mature_308_residues
SVLVYAEHDNAALNKVTLSVVAAAKEIGGDITVLVAGKGCGPVAEEAAKIDGVSKVLCADNDAYEHQLAENIGDLVAEVA
GDYSHILAAATTTGKNFAPRAAALLDVAQISEISDVIDADTFKRPIYAGNAIATVKCGDAKKVITVRGTSFDGVAAEGGS
ASVENIDVAKDAGISSFVGEELAKSDRPELTSAEIVISGGRGMGNGENFEILYKLADKLGAGVGASRAAVDAGFVPNDMQ
VGQTGKIVAPNLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEAVPELDGKL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=59.8039215686275, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI189181759, Length=264, Percent_Identity=62.1212121212121, Blast_Score=326, Evalue=2e-89,
Organism=Escherichia coli, GI1786226, Length=228, Percent_Identity=32.4561403508772, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787990, Length=259, Percent_Identity=33.2046332046332, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082157, Length=214, Percent_Identity=32.7102803738318, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=313, Percent_Identity=55.591054313099, Blast_Score=339, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6325261, Length=296, Percent_Identity=44.2567567567568, Blast_Score=248, Evalue=6e-67,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=63.9871382636656, Blast_Score=385, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=63.9871382636656, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31618; Mature: 31487

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVYAEHDNAALNKVTLSVVAAAKEIGGDITVLVAGKGCGPVAEEAAKIDGVSKVLCA
CEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEC
DNDAYEHQLAENIGDLVAEVAGDYSHILAAATTTGKNFAPRAAALLDVAQISEISDVIDA
CCHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
DTFKRPIYAGNAIATVKCGDAKKVITVRGTSFDGVAAEGGSASVENIDVAKDAGISSFVG
HHHCCCEECCCEEEEEEECCCCEEEEEECCCCCCEECCCCCCCCCCEECHHHCCHHHHHH
EELAKSDRPELTSAEIVISGGRGMGNGENFEILYKLADKLGAGVGASRAAVDAGFVPNDM
HHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCC
QVGQTGKIVAPNLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
EECCCCCEECCCEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
AVPELDGKL
HHHHCCCCC
>Mature Secondary Structure 
SVLVYAEHDNAALNKVTLSVVAAAKEIGGDITVLVAGKGCGPVAEEAAKIDGVSKVLCA
EEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEC
DNDAYEHQLAENIGDLVAEVAGDYSHILAAATTTGKNFAPRAAALLDVAQISEISDVIDA
CCHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
DTFKRPIYAGNAIATVKCGDAKKVITVRGTSFDGVAAEGGSASVENIDVAKDAGISSFVG
HHHCCCEECCCEEEEEEECCCCEEEEEECCCCCCEECCCCCCCCCCEECHHHCCHHHHHH
EELAKSDRPELTSAEIVISGGRGMGNGENFEILYKLADKLGAGVGASRAAVDAGFVPNDM
HHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCC
QVGQTGKIVAPNLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
EECCCCCEECCCEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
AVPELDGKL
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]