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The map label for this gene is pt [C]

Identifier: 110833919

GI number: 110833919

Start: 1199746

End: 1200219

Strand: Direct

Name: pt [C]

Synonym: ABO_1058

Alternate gene names: 110833919

Gene position: 1199746-1200219 (Clockwise)

Preceding gene: 110833918

Following gene: 110833920

Centisome position: 38.45

GC content: 55.27

Gene sequence:

>474_bases
ATGAGCGTGTCTGTGTTATTTGTTTGTCTCGGGAATATTTGCCGTTCGCCTACCGCTGAAGTGGTTTTTCGGACGCGAGT
GAAGGCAGCTGGGCTTGAGGACCGTATTCACATAGATAGCGTTGGAACCGGTGATTGGCATATCGGTAAGGCGCCGGACC
CGCGTACTCAAGAGGCGGCTTTGCGGCGAGGATATTCAATGGCGGCTTTGCGAGCACGGCAGGTCAGTCCTGCGGACTTT
GCCAACTTTGATTGGGTGTTGGCCATGGATAACGCCAACCTAGCGGATCTTGAGGTTATGCGCCCGGCATCGTACCAAGG
AACTCTCGCGCGGTTTTTGGATTTTGCAGACCACACTGGGGTGCAGGAAGTGCCCGATCCTTATTATGGCGGCGAAGACG
GTTTCGACACGGTGTTGGACTTGATTGAAGAGGGTGCCGATGGATTGTTGCGCCGTGTGCGGGAGCAGCTGTGA

Upstream 100 bases:

>100_bases
GGGTAGCGATTCATGTGGAGCCTGCCTGTGAAGTGGTTCCTGGCGGTGTGGATACACAGACGGATCTTGAACGTTTGCGA
GCCCAGCTGGGAGGCCAATA

Downstream 100 bases:

>100_bases
GCGAGTCGGTACCACCAACCCACACTTTCACACAGATTGATGATGCGGATTTGACGGGGCTGAACACCCTAGGCCTGCCG
GCCCGGGCTCAACGTTTAGC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSVSVLFVCLGNICRSPTAEVVFRTRVKAAGLEDRIHIDSVGTGDWHIGKAPDPRTQEAALRRGYSMAALRARQVSPADF
ANFDWVLAMDNANLADLEVMRPASYQGTLARFLDFADHTGVQEVPDPYYGGEDGFDTVLDLIEEGADGLLRRVREQL

Sequences:

>Translated_157_residues
MSVSVLFVCLGNICRSPTAEVVFRTRVKAAGLEDRIHIDSVGTGDWHIGKAPDPRTQEAALRRGYSMAALRARQVSPADF
ANFDWVLAMDNANLADLEVMRPASYQGTLARFLDFADHTGVQEVPDPYYGGEDGFDTVLDLIEEGADGLLRRVREQL
>Mature_156_residues
SVSVLFVCLGNICRSPTAEVVFRTRVKAAGLEDRIHIDSVGTGDWHIGKAPDPRTQEAALRRGYSMAALRARQVSPADFA
NFDWVLAMDNANLADLEVMRPASYQGTLARFLDFADHTGVQEVPDPYYGGEDGFDTVLDLIEEGADGLLRRVREQL

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=138, Percent_Identity=42.7536231884058, Blast_Score=110, Evalue=5e-25,
Organism=Homo sapiens, GI4757714, Length=138, Percent_Identity=42.0289855072464, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI96304457, Length=77, Percent_Identity=48.0519480519481, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1788375, Length=146, Percent_Identity=31.5068493150685, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI87081812, Length=151, Percent_Identity=27.8145695364238, Blast_Score=64, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=154, Percent_Identity=31.8181818181818, Blast_Score=106, Evalue=1e-24,
Organism=Drosophila melanogaster, GI78706770, Length=155, Percent_Identity=38.7096774193548, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI78706772, Length=155, Percent_Identity=38.7096774193548, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI78706766, Length=138, Percent_Identity=36.231884057971, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI78706768, Length=138, Percent_Identity=36.231884057971, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI78706764, Length=129, Percent_Identity=35.6589147286822, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI78711846, Length=156, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17314; Mature: 17182

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSVLFVCLGNICRSPTAEVVFRTRVKAAGLEDRIHIDSVGTGDWHIGKAPDPRTQEAA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCEECCCCCCCCHHHHH
LRRGYSMAALRARQVSPADFANFDWVLAMDNANLADLEVMRPASYQGTLARFLDFADHTG
HHCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCC
VQEVPDPYYGGEDGFDTVLDLIEEGADGLLRRVREQL
CCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHC
>Mature Secondary Structure 
SVSVLFVCLGNICRSPTAEVVFRTRVKAAGLEDRIHIDSVGTGDWHIGKAPDPRTQEAA
CHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCEECCCCCCCCHHHHH
LRRGYSMAALRARQVSPADFANFDWVLAMDNANLADLEVMRPASYQGTLARFLDFADHTG
HHCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCC
VQEVPDPYYGGEDGFDTVLDLIEEGADGLLRRVREQL
CCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]