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The map label for this gene is ugd2 [H]

Identifier: 110833796

GI number: 110833796

Start: 1046942

End: 1048231

Strand: Direct

Name: ugd2 [H]

Synonym: ABO_0935

Alternate gene names: 110833796

Gene position: 1046942-1048231 (Clockwise)

Preceding gene: 110833795

Following gene: 110833797

Centisome position: 33.55

GC content: 53.72

Gene sequence:

>1290_bases
ATGCAGGTGGCGGTTTATGGCGACACGTTATGCGCCCAGGTAACGGCAACGGCGCTTGCTCAGACCGGGCATCAGGTAGC
TTGGTACGTATTTGGTATAGAGGAGCATGAGCAGCTAAATCAAGAGCAACCGTTATTTAACGAGCAAGGGCTGGACCGCT
TGTATGTTGAGCAGATCAGCGCGGGCCGTTTGGTTCCTTTGTTAAGAGGACAAAGCGCAGTTGATATCTCGCCCTCGGAG
GTGGTGTTTCTTGCTTTGTCACCGGGTAGCGAAACCTTGGCAGAGGATATTCTCGCTGTTGATGTAAAGCCTGGCGCTTG
TCGATTGGTGGTGAACCAGACCGTGGGGCCCGTAGGGGTGGCGGAACGATTGCGGCAATACTTATTGTCTGCAGGCTATG
ATGCGGCTCTAGTGGCTTTGCCAGATTTGATTCAGGAGGGGAATGCCTTCCTGACCTTTACTCGTCCTGAGAGTATTTTG
CTGGGGTGTTATGAGCGCGAAGGCGAGGCCCTGATGCGTGAGCTGCTGCGCCCTTTCAATCGGCGTAAAGATGTTCTTCA
GGTGATGAGCCTGCGGGAGGCGGAGTTCGCAAAACTCGCCATCAGCGGCATTTTGGCTACCCGAATCAGTTTTATGAATG
ACATGGCCGCCTTATCGGAGTCGTTGGACGTGGATATTGATGCGGTACGCGTCGCAATGGGGGCAGACTCTCGTATAGGT
GAGGCTTACCTTTACCCGGGATGCGGATTTGGCGGGCCTGGCTTGAGCAGTAATGTACTGGCTTTGCTGGATGCTCAGCA
GCAGAAAGCCGCGGAGCCTGGTTTACTCGAGCAGGTGTTGCATACCAATGAACGGCAAAAAGAAGTTCTGTTTCGCAAGT
TTTGGCAGTACTGCAACGGCTGTGTAAAAGGTAAGCGGGTTGCGATCTGGGGGGCGTCCTTCAAGCCGGGCACAGCCCGG
GTAGAAAACGCGCCTGCCTTGAAGATTATAGAAGCGTTATGGGCGCAGGGTGTGGACGTGGCTGTGCATGATCCCAAGGC
CTTGCCCGATTTAAAACGCTGGGCTGAGAAGCAAAATAGAAAACTGTTGCTGTGTGATACCCCCTACGAGGCCACCTTGG
GCGCCGATGCATTGATGCTGGTCACCGAGTGGAAACCTTATTGGAGCCCAGATTGGCAGCGTTTGAAACAAGAGATGCGG
ACCGGGCTTATTCTCGATGGCCGTAATATTTATGACCCTGCATTTGTTAAGGCACAGGGGCTGGAATATCGTGGAATTGG
ACGGAGCTAG

Upstream 100 bases:

>100_bases
CCGAAGCTAGCCAGCACTAATGTGGATGGTTTATTGGGCTCTGCAGGTACTTTGCTTGCGGGTGTCTATCGTATGAGGAT
AACGCGAAGGGTTTGGTGAT

Downstream 100 bases:

>100_bases
GCATGGTGCCTGAACAAAATGATCTAACCGAGAGTTCGGTCTGGCTGCAGCTTGAAAACCTTGCACGTGAGGAAGGCTCT
TTGCATTTGTCTGATTTTTT

Product: NDP-sugar dehydrogenase like UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MQVAVYGDTLCAQVTATALAQTGHQVAWYVFGIEEHEQLNQEQPLFNEQGLDRLYVEQISAGRLVPLLRGQSAVDISPSE
VVFLALSPGSETLAEDILAVDVKPGACRLVVNQTVGPVGVAERLRQYLLSAGYDAALVALPDLIQEGNAFLTFTRPESIL
LGCYEREGEALMRELLRPFNRRKDVLQVMSLREAEFAKLAISGILATRISFMNDMAALSESLDVDIDAVRVAMGADSRIG
EAYLYPGCGFGGPGLSSNVLALLDAQQQKAAEPGLLEQVLHTNERQKEVLFRKFWQYCNGCVKGKRVAIWGASFKPGTAR
VENAPALKIIEALWAQGVDVAVHDPKALPDLKRWAEKQNRKLLLCDTPYEATLGADALMLVTEWKPYWSPDWQRLKQEMR
TGLILDGRNIYDPAFVKAQGLEYRGIGRS

Sequences:

>Translated_429_residues
MQVAVYGDTLCAQVTATALAQTGHQVAWYVFGIEEHEQLNQEQPLFNEQGLDRLYVEQISAGRLVPLLRGQSAVDISPSE
VVFLALSPGSETLAEDILAVDVKPGACRLVVNQTVGPVGVAERLRQYLLSAGYDAALVALPDLIQEGNAFLTFTRPESIL
LGCYEREGEALMRELLRPFNRRKDVLQVMSLREAEFAKLAISGILATRISFMNDMAALSESLDVDIDAVRVAMGADSRIG
EAYLYPGCGFGGPGLSSNVLALLDAQQQKAAEPGLLEQVLHTNERQKEVLFRKFWQYCNGCVKGKRVAIWGASFKPGTAR
VENAPALKIIEALWAQGVDVAVHDPKALPDLKRWAEKQNRKLLLCDTPYEATLGADALMLVTEWKPYWSPDWQRLKQEMR
TGLILDGRNIYDPAFVKAQGLEYRGIGRS
>Mature_429_residues
MQVAVYGDTLCAQVTATALAQTGHQVAWYVFGIEEHEQLNQEQPLFNEQGLDRLYVEQISAGRLVPLLRGQSAVDISPSE
VVFLALSPGSETLAEDILAVDVKPGACRLVVNQTVGPVGVAERLRQYLLSAGYDAALVALPDLIQEGNAFLTFTRPESIL
LGCYEREGEALMRELLRPFNRRKDVLQVMSLREAEFAKLAISGILATRISFMNDMAALSESLDVDIDAVRVAMGADSRIG
EAYLYPGCGFGGPGLSSNVLALLDAQQQKAAEPGLLEQVLHTNERQKEVLFRKFWQYCNGCVKGKRVAIWGASFKPGTAR
VENAPALKIIEALWAQGVDVAVHDPKALPDLKRWAEKQNRKLLLCDTPYEATLGADALMLVTEWKPYWSPDWQRLKQEMR
TGLILDGRNIYDPAFVKAQGLEYRGIGRS

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=342, Percent_Identity=26.9005847953216, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI296040438, Length=342, Percent_Identity=26.9005847953216, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI296040443, Length=311, Percent_Identity=27.6527331189711, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI1788340, Length=255, Percent_Identity=23.1372549019608, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560350, Length=343, Percent_Identity=27.1137026239067, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136908, Length=341, Percent_Identity=27.5659824046921, Blast_Score=132, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47349; Mature: 47349

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVAVYGDTLCAQVTATALAQTGHQVAWYVFGIEEHEQLNQEQPLFNEQGLDRLYVEQIS
CEEEEECCHHHHHHHHHHHHHCCCEEEEEEEECHHHHHCCCCCCCCCCCCCHHHHHHHHC
AGRLVPLLRGQSAVDISPSEVVFLALSPGSETLAEDILAVDVKPGACRLVVNQTVGPVGV
CCCEEHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHEEEECCCCCEEEEEECCCCCHHH
AERLRQYLLSAGYDAALVALPDLIQEGNAFLTFTRPESILLGCYEREGEALMRELLRPFN
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCEEEEEEHHCCHHHHHHHHHHHHH
RRKDVLQVMSLREAEFAKLAISGILATRISFMNDMAALSESLDVDIDAVRVAMGADSRIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCC
EAYLYPGCGFGGPGLSSNVLALLDAQQQKAAEPGLLEQVLHTNERQKEVLFRKFWQYCNG
CEEECCCCCCCCCCCCCCCEEEEECHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHH
CVKGKRVAIWGASFKPGTARVENAPALKIIEALWAQGVDVAVHDPKALPDLKRWAEKQNR
HCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCC
KLLLCDTPYEATLGADALMLVTEWKPYWSPDWQRLKQEMRTGLILDGRNIYDPAFVKAQG
EEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCEEECC
LEYRGIGRS
CEECCCCCC
>Mature Secondary Structure
MQVAVYGDTLCAQVTATALAQTGHQVAWYVFGIEEHEQLNQEQPLFNEQGLDRLYVEQIS
CEEEEECCHHHHHHHHHHHHHCCCEEEEEEEECHHHHHCCCCCCCCCCCCCHHHHHHHHC
AGRLVPLLRGQSAVDISPSEVVFLALSPGSETLAEDILAVDVKPGACRLVVNQTVGPVGV
CCCEEHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHEEEECCCCCEEEEEECCCCCHHH
AERLRQYLLSAGYDAALVALPDLIQEGNAFLTFTRPESILLGCYEREGEALMRELLRPFN
HHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCEEEEEEHHCCHHHHHHHHHHHHH
RRKDVLQVMSLREAEFAKLAISGILATRISFMNDMAALSESLDVDIDAVRVAMGADSRIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCC
EAYLYPGCGFGGPGLSSNVLALLDAQQQKAAEPGLLEQVLHTNERQKEVLFRKFWQYCNG
CEEECCCCCCCCCCCCCCCEEEEECHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHH
CVKGKRVAIWGASFKPGTARVENAPALKIIEALWAQGVDVAVHDPKALPDLKRWAEKQNR
HCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCC
KLLLCDTPYEATLGADALMLVTEWKPYWSPDWQRLKQEMRTGLILDGRNIYDPAFVKAQG
EEEEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCEEECC
LEYRGIGRS
CEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]