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The map label for this gene is 110833792

Identifier: 110833792

GI number: 110833792

Start: 1042693

End: 1044129

Strand: Direct

Name: 110833792

Synonym: ABO_0931

Alternate gene names: NA

Gene position: 1042693-1044129 (Clockwise)

Preceding gene: 110833791

Following gene: 110833793

Centisome position: 33.42

GC content: 57.69

Gene sequence:

>1437_bases
ATGGAACGTTCCAATAACCTGCCTGAAGGCGGGTTTCCTCATCTTTTTCATCATGGTGCCGTGCGTGGTGTAACGGGTTC
CGCCCATGAATGGGTGGCTAGCCCAGATTGCTCTGTGCTCATCGACTGTGGGCTTTTCCAGGGCGGTGATGTTGGTCCAG
CTGGGGCTAGCGCAGATGATTTGGCCATCGATTTCGATATTTCCCGGATCCAGGCAGTGGTGCTCACCCATGTGCATATT
GATCATGTGGGGCGGCTGCCGTGGTTGTTGGGTGCGGGTTATGTCGGGCCGATTTGCTGTAGTGGCCCATCGGCCAAGCT
GCTGCCCATTGTGTTGGAAGATGCCTTTCGCTTAGGGGTGAGCCGCAAGCCGGCAGATGTGGAGCGCTTTATGGCGCGGC
TGGAGGCGGCGTTAGTGCCTGTGCCGTTTGGTTATTGGCATGCCCTGGAGATGGCTGATGGAACGGTGGCGGAGATTCGC
TTGGGCAGGGCGGGGCATATTTTGGGCTCGGCCCATGTGTCTTGCCGATTGGCCGGTGAGCACATCACGGTGTTTTCCGG
GGATTTAGGGGCTGCTGATGCGCCAATTCTGCCGGAACCGGAGCCCCCACCGGCTGCGAATGTGTTGGTGATAGAAAGCA
CCTACGGGGATAGTCTTCATGAAGGGCGGAAGACGCGGCAGCAGCGCTTAGAAGATGCGTTGGTTAAGGCCTTACGTGAC
AAGGGGACTTTATTGATTCCTGCGTTCAGTATTGGCCGTACCCAAGAGCTGCTTTATGAGTTGGAGGCGATTATCCACCG
CCAACGGGGCGCCGCCATGCATTCGTTTCTGGACTGGGATGAGTTGCCGATAATCCTTGATTCTCCATTGGCGAGCCGGT
TTACCCAGGTTTACCGGGAGCTTGAGCCTTACTGGGACGAGGAGGCCCGCGAACGCTTGCGGGCAGACCGCCGGCCGTTG
GCGTTTGAACAGCTACTAACGGTGGACAGCCATGAGGCACACATGAAAATGGTTCGTCACTTGGCTGGCACCGCAAGGCC
GGCGGTGGTGATTGCCGCCAGTGGCATGTGTGCCGGTGGCCGCATTGTGAATTACCTAAAAGCGATGCTGGGCGATGCGC
GCCACAATGTGCTGTTTGTGGGGTATCAAGCTGCGGGGACGCCGGGCAGGGAGATTCAGCGAAGCGAGCAGGGCGGCAGT
GTGAGGCTAGAGGCAGAAACCTACCCCATTCGAGCTGCAGTAGAATCCATTAGCGGTTATTCAGCCCATGGTGATCAGCA
GGATTTGCTTCGGTTCGCGGCAGGAATAGCGCGGGGGCCTGAAGAAATTCGCGTGGTGCACGGTGATGAAGGCGCTAAGC
GTGCTCTGGTCGATAAGCTTGATACACATTTTCGAGCCGCCGGCCAGCCAGTGAACGTTTGGATTCCACTCCAATAG

Upstream 100 bases:

>100_bases
GCGCAGAACGGATTAAGCATAACCGTAATGCGGTATTGTGCGGTGATCGGATTTGCCCCGGGCCAAGGAGGGCCTGCCTC
GACATTGTGGAGGAGTTCAC

Downstream 100 bases:

>100_bases
CGGCTTATTGCATCCACGTTTACGGGTTTGTCGGTGCGGAGCTTCCATTCATTTCCGTGTGAAAAGGATAGGGCCAATGG
ATTGGCTTCTTATCAACAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MERSNNLPEGGFPHLFHHGAVRGVTGSAHEWVASPDCSVLIDCGLFQGGDVGPAGASADDLAIDFDISRIQAVVLTHVHI
DHVGRLPWLLGAGYVGPICCSGPSAKLLPIVLEDAFRLGVSRKPADVERFMARLEAALVPVPFGYWHALEMADGTVAEIR
LGRAGHILGSAHVSCRLAGEHITVFSGDLGAADAPILPEPEPPPAANVLVIESTYGDSLHEGRKTRQQRLEDALVKALRD
KGTLLIPAFSIGRTQELLYELEAIIHRQRGAAMHSFLDWDELPIILDSPLASRFTQVYRELEPYWDEEARERLRADRRPL
AFEQLLTVDSHEAHMKMVRHLAGTARPAVVIAASGMCAGGRIVNYLKAMLGDARHNVLFVGYQAAGTPGREIQRSEQGGS
VRLEAETYPIRAAVESISGYSAHGDQQDLLRFAAGIARGPEEIRVVHGDEGAKRALVDKLDTHFRAAGQPVNVWIPLQ

Sequences:

>Translated_478_residues
MERSNNLPEGGFPHLFHHGAVRGVTGSAHEWVASPDCSVLIDCGLFQGGDVGPAGASADDLAIDFDISRIQAVVLTHVHI
DHVGRLPWLLGAGYVGPICCSGPSAKLLPIVLEDAFRLGVSRKPADVERFMARLEAALVPVPFGYWHALEMADGTVAEIR
LGRAGHILGSAHVSCRLAGEHITVFSGDLGAADAPILPEPEPPPAANVLVIESTYGDSLHEGRKTRQQRLEDALVKALRD
KGTLLIPAFSIGRTQELLYELEAIIHRQRGAAMHSFLDWDELPIILDSPLASRFTQVYRELEPYWDEEARERLRADRRPL
AFEQLLTVDSHEAHMKMVRHLAGTARPAVVIAASGMCAGGRIVNYLKAMLGDARHNVLFVGYQAAGTPGREIQRSEQGGS
VRLEAETYPIRAAVESISGYSAHGDQQDLLRFAAGIARGPEEIRVVHGDEGAKRALVDKLDTHFRAAGQPVNVWIPLQ
>Mature_478_residues
MERSNNLPEGGFPHLFHHGAVRGVTGSAHEWVASPDCSVLIDCGLFQGGDVGPAGASADDLAIDFDISRIQAVVLTHVHI
DHVGRLPWLLGAGYVGPICCSGPSAKLLPIVLEDAFRLGVSRKPADVERFMARLEAALVPVPFGYWHALEMADGTVAEIR
LGRAGHILGSAHVSCRLAGEHITVFSGDLGAADAPILPEPEPPPAANVLVIESTYGDSLHEGRKTRQQRLEDALVKALRD
KGTLLIPAFSIGRTQELLYELEAIIHRQRGAAMHSFLDWDELPIILDSPLASRFTQVYRELEPYWDEEARERLRADRRPL
AFEQLLTVDSHEAHMKMVRHLAGTARPAVVIAASGMCAGGRIVNYLKAMLGDARHNVLFVGYQAAGTPGREIQRSEQGGS
VRLEAETYPIRAAVESISGYSAHGDQQDLLRFAAGIARGPEEIRVVHGDEGAKRALVDKLDTHFRAAGQPVNVWIPLQ

Specific function: Has endoribonuclease activity towards 23S and 16S rRNA (in vitro) [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family [H]

Homologues:

Organism=Homo sapiens, GI33300633, Length=457, Percent_Identity=25.601750547046, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI7706427, Length=421, Percent_Identity=26.603325415677, Blast_Score=132, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI32564696, Length=450, Percent_Identity=26.2222222222222, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32566029, Length=452, Percent_Identity=26.9911504424779, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323307, Length=427, Percent_Identity=24.824355971897, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24648013, Length=445, Percent_Identity=26.2921348314607, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21358523, Length=472, Percent_Identity=24.7881355932203, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 51930; Mature: 51930

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSNNLPEGGFPHLFHHGAVRGVTGSAHEWVASPDCSVLIDCGLFQGGDVGPAGASADD
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
LAIDFDISRIQAVVLTHVHIDHVGRLPWLLGAGYVGPICCSGPSAKLLPIVLEDAFRLGV
EEEEECHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHCC
SRKPADVERFMARLEAALVPVPFGYWHALEMADGTVAEIRLGRAGHILGSAHVSCRLAGE
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEECCCCCEEECCEEEEEEECC
HITVFSGDLGAADAPILPEPEPPPAANVLVIESTYGDSLHEGRKTRQQRLEDALVKALRD
EEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
KGTLLIPAFSIGRTQELLYELEAIIHRQRGAAMHSFLDWDELPIILDSPLASRFTQVYRE
CCCEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCEEECCHHHHHHHHHHHH
LEPYWDEEARERLRADRRPLAFEQLLTVDSHEAHMKMVRHLAGTARPAVVIAASGMCAGG
HCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCH
RIVNYLKAMLGDARHNVLFVGYQAAGTPGREIQRSEQGGSVRLEAETYPIRAAVESISGY
HHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHCCC
SAHGDQQDLLRFAAGIARGPEEIRVVHGDEGAKRALVDKLDTHFRAAGQPVNVWIPLQ
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MERSNNLPEGGFPHLFHHGAVRGVTGSAHEWVASPDCSVLIDCGLFQGGDVGPAGASADD
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
LAIDFDISRIQAVVLTHVHIDHVGRLPWLLGAGYVGPICCSGPSAKLLPIVLEDAFRLGV
EEEEECHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHCC
SRKPADVERFMARLEAALVPVPFGYWHALEMADGTVAEIRLGRAGHILGSAHVSCRLAGE
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEECCCCCEEECCEEEEEEECC
HITVFSGDLGAADAPILPEPEPPPAANVLVIESTYGDSLHEGRKTRQQRLEDALVKALRD
EEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
KGTLLIPAFSIGRTQELLYELEAIIHRQRGAAMHSFLDWDELPIILDSPLASRFTQVYRE
CCCEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCEEECCHHHHHHHHHHHH
LEPYWDEEARERLRADRRPLAFEQLLTVDSHEAHMKMVRHLAGTARPAVVIAASGMCAGG
HCCCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCH
RIVNYLKAMLGDARHNVLFVGYQAAGTPGREIQRSEQGGSVRLEAETYPIRAAVESISGY
HHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHCCC
SAHGDQQDLLRFAAGIARGPEEIRVVHGDEGAKRALVDKLDTHFRAAGQPVNVWIPLQ
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA