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The map label for this gene is cfa [H]

Identifier: 110833689

GI number: 110833689

Start: 920235

End: 921251

Strand: Direct

Name: cfa [H]

Synonym: ABO_0828

Alternate gene names: 110833689

Gene position: 920235-921251 (Clockwise)

Preceding gene: 110833688

Following gene: 110833690

Centisome position: 29.49

GC content: 50.54

Gene sequence:

>1017_bases
ATGATGATTCAAATGGCTGAATCTGGCCTGTTACCCGATGGGCTGGTGCGTTTGGGTATTCGTCGTCTGTTGAGACAGCG
GCTGCAGCAGGAAAAACAGCGCGATAACCGTCAGACCTTTGAAGCGGCTCTCCAGCAGGGGCCAGTGGCGGTGGGCCAAG
ATGAAGCCAATGAGCAGCATTATGAAGTAGATGCTCGGTTTTATGAGCAGGTATTGGGCTCACATTTGAAGTACTCCAGC
GGCTATTGGCCTAGTTCATCGAGTTGCTTGGACGATGCTGAACGGGCGATGTTGGCCATGACCTGTGAGCGAGCTGATTT
GTTAGATGGTCAAGATGTGCTGGAAATGGGTTGTGGGTGGGGGTCATTGACACTGTGGATGGCTAAACAGTATCCCAATA
GTCGGATTACAGCGATTTCCAATTCGTCATCCCAGCGAGCCTTTATTTTAGGGCGCGCTGCTGAGCGCGGATTGGATAAT
GTGGACGTGATTACCGTCGATGCTTCCCAGTATCAGCCTTCCAAGCCCTATGACAGGGTGGTTTCGGTAGAAATGTTCGA
ACATATGCGAAATCACAAAACCTTGATGTTACGTATTCACGATTGGTTGAAGCCGGGGGGGAAATTATTCATCCATGTGT
TCTGCCATCATGATCTGACGTACCTGTTTGAGACGGAAGGCAGCAAGGACTGGATGGCTAAGTATTTTTTCACCGGTGGA
ATGATGCCTGCCTATGATTGGCTGCCGCAGTGCGCGGGGAACCTTGAGGAGGAACAGCGTTGGGCGGTGAATGGGACGCA
CTATGCACGAACGCTGGAGGCCTGGTTGGTGTTGGCGGATGAAAAGCGTGAACAGTTGATTCTCCTGCTGGATGAAGTTT
ATGGCGAGGGGAAAGGTAAAGTCTGGTTGCAGCGTTGGCGTATATTTTTCATGGCGTGTGCTGAGTTGTTTAACTATGGT
GAGGGACAAGAGTGGTTTGTTGCACACTACCGTTTCAGTAAAGCTGTTGTCAGTTGA

Upstream 100 bases:

>100_bases
GCATTCCGTATACCGAAAAACAGGCGCTGAAATCCCGCGGTGATAATTACCGTGACTACCAGCGCACCACGAGTGCGTTC
TTTCCTTGGAGACCTAAATC

Downstream 100 bases:

>100_bases
GCCGGCGATATTGCGGCCATTGATGTAACGTTTTGATGATGAGTTATGCATGAAAAAAACCGGCGTCCAGCATCGTATAA
CCCGTGTCTATCTGGTTCAG

Product: hypothetical protein

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MMIQMAESGLLPDGLVRLGIRRLLRQRLQQEKQRDNRQTFEAALQQGPVAVGQDEANEQHYEVDARFYEQVLGSHLKYSS
GYWPSSSSCLDDAERAMLAMTCERADLLDGQDVLEMGCGWGSLTLWMAKQYPNSRITAISNSSSQRAFILGRAAERGLDN
VDVITVDASQYQPSKPYDRVVSVEMFEHMRNHKTLMLRIHDWLKPGGKLFIHVFCHHDLTYLFETEGSKDWMAKYFFTGG
MMPAYDWLPQCAGNLEEEQRWAVNGTHYARTLEAWLVLADEKREQLILLLDEVYGEGKGKVWLQRWRIFFMACAELFNYG
EGQEWFVAHYRFSKAVVS

Sequences:

>Translated_338_residues
MMIQMAESGLLPDGLVRLGIRRLLRQRLQQEKQRDNRQTFEAALQQGPVAVGQDEANEQHYEVDARFYEQVLGSHLKYSS
GYWPSSSSCLDDAERAMLAMTCERADLLDGQDVLEMGCGWGSLTLWMAKQYPNSRITAISNSSSQRAFILGRAAERGLDN
VDVITVDASQYQPSKPYDRVVSVEMFEHMRNHKTLMLRIHDWLKPGGKLFIHVFCHHDLTYLFETEGSKDWMAKYFFTGG
MMPAYDWLPQCAGNLEEEQRWAVNGTHYARTLEAWLVLADEKREQLILLLDEVYGEGKGKVWLQRWRIFFMACAELFNYG
EGQEWFVAHYRFSKAVVS
>Mature_338_residues
MMIQMAESGLLPDGLVRLGIRRLLRQRLQQEKQRDNRQTFEAALQQGPVAVGQDEANEQHYEVDARFYEQVLGSHLKYSS
GYWPSSSSCLDDAERAMLAMTCERADLLDGQDVLEMGCGWGSLTLWMAKQYPNSRITAISNSSSQRAFILGRAAERGLDN
VDVITVDASQYQPSKPYDRVVSVEMFEHMRNHKTLMLRIHDWLKPGGKLFIHVFCHHDLTYLFETEGSKDWMAKYFFTGG
MMPAYDWLPQCAGNLEEEQRWAVNGTHYARTLEAWLVLADEKREQLILLLDEVYGEGKGKVWLQRWRIFFMACAELFNYG
EGQEWFVAHYRFSKAVVS

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=282, Percent_Identity=27.3049645390071, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI133904226, Length=279, Percent_Identity=26.5232974910394, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 39020; Mature: 39020

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIQMAESGLLPDGLVRLGIRRLLRQRLQQEKQRDNRQTFEAALQQGPVAVGQDEANEQH
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHH
YEVDARFYEQVLGSHLKYSSGYWPSSSSCLDDAERAMLAMTCERADLLDGQDVLEMGCGW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
GSLTLWMAKQYPNSRITAISNSSSQRAFILGRAAERGLDNVDVITVDASQYQPSKPYDRV
CHHHEEEHHHCCCCEEEEEECCCCCEEEEEECHHHCCCCCCEEEEEECCCCCCCCCHHHH
VSVEMFEHMRNHKTLMLRIHDWLKPGGKLFIHVFCHHDLTYLFETEGSKDWMAKYFFTGG
HHHHHHHHHHCCCEEEEEEHHHHCCCCEEEEEEEEECCEEEEEECCCCHHHHHHHHHCCC
MMPAYDWLPQCAGNLEEEQRWAVNGTHYARTLEAWLVLADEKREQLILLLDEVYGEGKGK
CCHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCCCH
VWLQRWRIFFMACAELFNYGEGQEWFVAHYRFSKAVVS
HHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCC
>Mature Secondary Structure
MMIQMAESGLLPDGLVRLGIRRLLRQRLQQEKQRDNRQTFEAALQQGPVAVGQDEANEQH
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHH
YEVDARFYEQVLGSHLKYSSGYWPSSSSCLDDAERAMLAMTCERADLLDGQDVLEMGCGW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
GSLTLWMAKQYPNSRITAISNSSSQRAFILGRAAERGLDNVDVITVDASQYQPSKPYDRV
CHHHEEEHHHCCCCEEEEEECCCCCEEEEEECHHHCCCCCCEEEEEECCCCCCCCCHHHH
VSVEMFEHMRNHKTLMLRIHDWLKPGGKLFIHVFCHHDLTYLFETEGSKDWMAKYFFTGG
HHHHHHHHHHCCCEEEEEEHHHHCCCCEEEEEEEEECCEEEEEECCCCHHHHHHHHHCCC
MMPAYDWLPQCAGNLEEEQRWAVNGTHYARTLEAWLVLADEKREQLILLLDEVYGEGKGK
CCHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCCCH
VWLQRWRIFFMACAELFNYGEGQEWFVAHYRFSKAVVS
HHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]