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The map label for this gene is queC [H]

Identifier: 110833623

GI number: 110833623

Start: 855931

End: 856614

Strand: Direct

Name: queC [H]

Synonym: ABO_0762

Alternate gene names: 110833623

Gene position: 855931-856614 (Clockwise)

Preceding gene: 110833622

Following gene: 110833625

Centisome position: 27.43

GC content: 53.36

Gene sequence:

>684_bases
ATGAAGGAACCTGCCATGAAAAAAGCCGTGGTGCTGTTGTCCGGTGGCTTGGATTCAGCCACTTGCTTGGCGATCGCCCG
TGATCAGGGCTATGCCTGCCATACCATTGCATTCGATTATGGCCAACGCACTCGGTCAGAGTTGGATGCGGCGGAGCGTG
TGTCTGGCGTGTTGGGGGCGTTGAGTCACCGTGTCATTGAGCTGGGTATGGGGAATATCGGCGGCTCTGCGTTGACGGAT
CATTCCATTGAGGTGCCGGAAAACGGGGGTGACGGTATTCCTGTGACCTATGTGCCGGCCCGTAACACGGTATTCCTGTC
TCTGGCGCTAGGTTTGGCGGAAGTGATTGATGCGCAAGCTATTTTTATTGGAGTGAATGCGGTGGACTATTCAGGCTATC
CAGATTGCCGGCCGGCGTTTATCGAGGCGTTTCAGTCCATGGCCACTTTAGCCACCAAGGCAGGGGTAGAAGGGAGGCCC
ATGCAGATTGAGACTCCGTTAATGCATTTGAGTAAAGCGCAGATTATTCAGCGGGGGGTGGCGTTGGGTTTGGATTACGG
TCTTACCGTCTCTTGTTATCAGGCTGACGATCATGGAAATGCTTGTGGGAAATGCGACAGTTGCCGTCTGCGCAGCCAAG
GCTTCGAGGATGCATTGGTTAAAGATCCAACAAACTATCAATAA

Upstream 100 bases:

>100_bases
ATAAGCTTCTTTGGAATGATGCTCGCGGACGCTGATTAAGGTCAGACGCAAGATCTCTATGCGCCAAACGTGAAGTCTCA
CAACCCTAAAGCAAAGAGTA

Downstream 100 bases:

>100_bases
AGCAGAAAAAAAATGGGTTAACCCCTTGTCACCAAGAAATAAATCCGTATTATTTGCGCCTCCTTCGGGAGCGGGTCGTT
AGCTCAGTTGGTAGAGCAGT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKEPAMKKAVVLLSGGLDSATCLAIARDQGYACHTIAFDYGQRTRSELDAAERVSGVLGALSHRVIELGMGNIGGSALTD
HSIEVPENGGDGIPVTYVPARNTVFLSLALGLAEVIDAQAIFIGVNAVDYSGYPDCRPAFIEAFQSMATLATKAGVEGRP
MQIETPLMHLSKAQIIQRGVALGLDYGLTVSCYQADDHGNACGKCDSCRLRSQGFEDALVKDPTNYQ

Sequences:

>Translated_227_residues
MKEPAMKKAVVLLSGGLDSATCLAIARDQGYACHTIAFDYGQRTRSELDAAERVSGVLGALSHRVIELGMGNIGGSALTD
HSIEVPENGGDGIPVTYVPARNTVFLSLALGLAEVIDAQAIFIGVNAVDYSGYPDCRPAFIEAFQSMATLATKAGVEGRP
MQIETPLMHLSKAQIIQRGVALGLDYGLTVSCYQADDHGNACGKCDSCRLRSQGFEDALVKDPTNYQ
>Mature_227_residues
MKEPAMKKAVVLLSGGLDSATCLAIARDQGYACHTIAFDYGQRTRSELDAAERVSGVLGALSHRVIELGMGNIGGSALTD
HSIEVPENGGDGIPVTYVPARNTVFLSLALGLAEVIDAQAIFIGVNAVDYSGYPDCRPAFIEAFQSMATLATKAGVEGRP
MQIETPLMHLSKAQIIQRGVALGLDYGLTVSCYQADDHGNACGKCDSCRLRSQGFEDALVKDPTNYQ

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=225, Percent_Identity=40.8888888888889, Blast_Score=160, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 24057; Mature: 24057

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEPAMKKAVVLLSGGLDSATCLAIARDQGYACHTIAFDYGQRTRSELDAAERVSGVLGA
CCCCHHHEEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LSHRVIELGMGNIGGSALTDHSIEVPENGGDGIPVTYVPARNTVFLSLALGLAEVIDAQA
HHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHCCCE
IFIGVNAVDYSGYPDCRPAFIEAFQSMATLATKAGVEGRPMQIETPLMHLSKAQIIQRGV
EEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHH
ALGLDYGLTVSCYQADDHGNACGKCDSCRLRSQGFEDALVKDPTNYQ
HCCCCCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MKEPAMKKAVVLLSGGLDSATCLAIARDQGYACHTIAFDYGQRTRSELDAAERVSGVLGA
CCCCHHHEEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LSHRVIELGMGNIGGSALTDHSIEVPENGGDGIPVTYVPARNTVFLSLALGLAEVIDAQA
HHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHCCCE
IFIGVNAVDYSGYPDCRPAFIEAFQSMATLATKAGVEGRPMQIETPLMHLSKAQIIQRGV
EEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHH
ALGLDYGLTVSCYQADDHGNACGKCDSCRLRSQGFEDALVKDPTNYQ
HCCCCCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA