Click here to switch to the map view.

The map label for this gene is ruvC

Identifier: 110833612

GI number: 110833612

Start: 847735

End: 848253

Strand: Direct

Name: ruvC

Synonym: ABO_0751

Alternate gene names: 110833612

Gene position: 847735-848253 (Clockwise)

Preceding gene: 110833611

Following gene: 110833613

Centisome position: 27.17

GC content: 56.07

Gene sequence:

>519_bases
ATGGCGCTTATTCTGGGTATTGATCCCGGTTCTCGACGCACCGGTTACGGCGTAGTGGATGTGGTGGGAAATCGTTCCCG
CGCGGTGGCTTTCGGTACTATTACGACTTCCCACAAGGAGATCCCGCCGCGGTTGGGTGAGATATTCGCGGGAATTGATC
AGGTGGTGAAGGAATACGGGCCGGCTGAAGTGAGCATCGAAAAAGTGTTTATGGCTCGCAATGCGGATTCTGCCCTGAAA
TTGGGCCAGGCTCGCGGTGCAGCTATTGCGGCAGTGATGCAGGCCTGTGTGCCAGTGTTTGAATATTCGGCTCGCCAAGT
AAAACAGGCCGTTGTGGGCAAAGGTGGGGCGGAAAAAAATCAGGTCGGGGAAATGGTGAAGTATCTGCTTAAACTGGATC
AACGCCCGCAGGAGGACGCCGCTGATGCCCTGGCTATCGCGCTTTGTCATGCTCATATGCGTCTCTCCCTGGCTAGAATG
GCTGGTGCCACATCGGTAAGGCGCGGCCGGGTTCGTTAG

Upstream 100 bases:

>100_bases
TCTTTGTTGGCTGGACATTTGGACAGTGCTCGGGTAGAACGGAGGCACCTACTAAGAGCTGGGCTGGGTGCCTGTCTTCT
TTATTATTGGTCTGTGAAAT

Downstream 100 bases:

>100_bases
TGTGGTGTCTGTATTCGTTGATTGCTTCAGTGATTGATTGTGAGCATCGAATATTCGCCCTGTATTTTCTACGCGATACT
TTTGTTGTGTACGGGTAAAT

Product: endonuclease RuvC

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MALILGIDPGSRRTGYGVVDVVGNRSRAVAFGTITTSHKEIPPRLGEIFAGIDQVVKEYGPAEVSIEKVFMARNADSALK
LGQARGAAIAAVMQACVPVFEYSARQVKQAVVGKGGAEKNQVGEMVKYLLKLDQRPQEDAADALAIALCHAHMRLSLARM
AGATSVRRGRVR

Sequences:

>Translated_172_residues
MALILGIDPGSRRTGYGVVDVVGNRSRAVAFGTITTSHKEIPPRLGEIFAGIDQVVKEYGPAEVSIEKVFMARNADSALK
LGQARGAAIAAVMQACVPVFEYSARQVKQAVVGKGGAEKNQVGEMVKYLLKLDQRPQEDAADALAIALCHAHMRLSLARM
AGATSVRRGRVR
>Mature_171_residues
ALILGIDPGSRRTGYGVVDVVGNRSRAVAFGTITTSHKEIPPRLGEIFAGIDQVVKEYGPAEVSIEKVFMARNADSALKL
GQARGAAIAAVMQACVPVFEYSARQVKQAVVGKGGAEKNQVGEMVKYLLKLDQRPQEDAADALAIALCHAHMRLSLARMA
GATSVRRGRVR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=173, Percent_Identity=54.3352601156069, Blast_Score=161, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_ALCBS (Q0VRJ9)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692471.1
- ProteinModelPortal:   Q0VRJ9
- SMR:   Q0VRJ9
- STRING:   Q0VRJ9
- GeneID:   4212639
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0751
- NMPDR:   fig|393595.12.peg.754
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   PMQIKLA
- PhylomeDB:   Q0VRJ9
- BioCyc:   ABOR393595:ABO_0751-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18359; Mature: 18227

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALILGIDPGSRRTGYGVVDVVGNRSRAVAFGTITTSHKEIPPRLGEIFAGIDQVVKEYG
CEEEEECCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
PAEVSIEKVFMARNADSALKLGQARGAAIAAVMQACVPVFEYSARQVKQAVVGKGGAEKN
CCCHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QVGEMVKYLLKLDQRPQEDAADALAIALCHAHMRLSLARMAGATSVRRGRVR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCC
>Mature Secondary Structure 
ALILGIDPGSRRTGYGVVDVVGNRSRAVAFGTITTSHKEIPPRLGEIFAGIDQVVKEYG
EEEEECCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
PAEVSIEKVFMARNADSALKLGQARGAAIAAVMQACVPVFEYSARQVKQAVVGKGGAEKN
CCCHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QVGEMVKYLLKLDQRPQEDAADALAIALCHAHMRLSLARMAGATSVRRGRVR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA