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The map label for this gene is aspS

Identifier: 110833610

GI number: 110833610

Start: 844886

End: 846649

Strand: Direct

Name: aspS

Synonym: ABO_0749

Alternate gene names: 110833610

Gene position: 844886-846649 (Clockwise)

Preceding gene: 110833601

Following gene: 110833611

Centisome position: 27.08

GC content: 55.05

Gene sequence:

>1764_bases
ATGCGAAGCCATTATTGCGGTGATTTGCGAGCCTCCCACGACGGAGAAACAGTAGAGCTTTGCGGTTGGGTCAGTCGCCG
CCGTGACCACGGTGGGGTGATCTTCCTCGACCTGCGTGACCGTAATGGTCTGGTGCAGGTGGTGTTTGATCCGGACACTG
TGGATGCCTTCGCGCTGGCTGACAAAGTACGCAGTGAATATGTGGTTCGCTTGAGCGGCCGGGTACGCATGCGTGACGAA
TCAGTGCGTAACAACAAGATGGCCACTGGTGATATCGAAGTCTTGGGTAAAGAGCTGACGATTCTTAATGAAGCGGAGAC
CCCGCCATTTGAGTTGGATGCCCACTCCGCCGCCGGTGAAGAGGTGCGTCTCAAGTACCGTTATATGGATCTGCGTCGTC
CGGACGTGTTGAAAAACTTCCAGTTCCGTTCGCGCCTGACTCATGTTGTGCGCGCCTTCCTGGAAGGCGAGGGTTTCATG
GATGTGGAAACGCCGATTCTGACCCGAGCGACGCCGGAAGGTGCACGGGATTACTTGGTGCCCAGCCGAACGCATCCGGG
TAGCTTTTTTGCGTTGCCGCAGTCTCCGCAGTTGTTCAAACAGCTATTGATGGTGGCGGGCTTTGATCGCTACTACCAGA
TTGCTAAGTGTTTCCGTGACGAAGACCTGCGAGCCGATCGCCAGCCAGAATTTACCCAGATTGATTTGGAAGCTTCCTTT
GTAGAGGAAGAAGACATTATGGGCATTACCGAACGGATGGTGCGTTCGGTGTTTAAAGAATTGCTCAGTGTAGACTTACC
GGATTTCCCGCGCATGCCATTCTCCGAGGCCATGCAGCGTTTCGGGTCCGACAAGCCTGACCTGCGTATTGCATTGGAGC
TGATTGATATTGCCGACCTGCTTGCTGGCGTGGACTTTAAAGTGTTCTCCGGCCCGGCCAACGACCCGAAAGGTCGTGTG
GCAGCCATGCGAGTGCCCGGTGGATGCAGCCTGTCGCGCAAGGATATCGATGGCTACACCAAGTTTGTCAGCATCTATGG
TGCCAAGGGTTTGGCTTACATCAAAGTCAACGACTTGGCAGCCGGCGCTGAAGGTCTGCAGTCTCCGATCCTGAAGTTCC
TGACCGAAGATGCGATTAAAGGCATCCTTGAGCGCACTGGCGCCGAGACCGGCGATCTGATTTTCTTCGGTGCTGATAAG
GCCAAGATCGTTAACGAAGCGCTGGGTGCTCTGCGCGTCAAAGTGGGCCATGACTTGAATTTGGTCGAGGGAGAATGGGC
GCCATTGTGGGTAGTGGACTTCCCCATGTTCGAGGAAGACGAAGGGCAATACCATGCGTTGCATCATCCCTTCACCATGC
CCAGCTGTAGCGCGGAAGAGCTTAAGAGTAATCCGGGCGAGGCGTTATCGCGGGCCTATGACATGGTGCTTAACGGTACT
GAGCTGGGTGGCGGTTCCATCCGTATCCATAGCCCAGCCATGCAACGCACTGTATTTGAAGCGCTGGGCATTTCTGATGA
GGAAGCCGAGGAAAAATTCGGCTTCCTGCTAGACGGTCTGAAATACGGCGCCCCGCCCCACGGTGGCCTGGCGTTTGGGT
TGGATCGCATGGTGATGTTGATGACTGGTTGTGAATCAATTCGTGATGTGATCGCTTTCCCGAAGACGCAAACGGCGGCG
TGCACTATGACCAATGCACCGTCACCGGTGGACAACAAGCAGCTGCGTGAAGTTGGCGTACAGGTACGTAAAGAAGAAGG
TTGA

Upstream 100 bases:

>100_bases
GCTATACTATGGCGCCTTTTTCAGTGGTCCGGCTTCGGGGTGGCTTCAGCCAGCCTTTGATCGCCGGGCGGCGTAATCAG
AATACAAGCGGATTTTAAGC

Downstream 100 bases:

>100_bases
TATAGGAGAAACGCAGGCAGGTATCACGCATCACGCGAAGAGGCGTGCCAGAGACGTGTTGCGTGACGCGTGCTGCGTGC
TGGCGGAGGTAACATGGCAG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MRSHYCGDLRASHDGETVELCGWVSRRRDHGGVIFLDLRDRNGLVQVVFDPDTVDAFALADKVRSEYVVRLSGRVRMRDE
SVRNNKMATGDIEVLGKELTILNEAETPPFELDAHSAAGEEVRLKYRYMDLRRPDVLKNFQFRSRLTHVVRAFLEGEGFM
DVETPILTRATPEGARDYLVPSRTHPGSFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
VEEEDIMGITERMVRSVFKELLSVDLPDFPRMPFSEAMQRFGSDKPDLRIALELIDIADLLAGVDFKVFSGPANDPKGRV
AAMRVPGGCSLSRKDIDGYTKFVSIYGAKGLAYIKVNDLAAGAEGLQSPILKFLTEDAIKGILERTGAETGDLIFFGADK
AKIVNEALGALRVKVGHDLNLVEGEWAPLWVVDFPMFEEDEGQYHALHHPFTMPSCSAEELKSNPGEALSRAYDMVLNGT
ELGGGSIRIHSPAMQRTVFEALGISDEEAEEKFGFLLDGLKYGAPPHGGLAFGLDRMVMLMTGCESIRDVIAFPKTQTAA
CTMTNAPSPVDNKQLREVGVQVRKEEG

Sequences:

>Translated_587_residues
MRSHYCGDLRASHDGETVELCGWVSRRRDHGGVIFLDLRDRNGLVQVVFDPDTVDAFALADKVRSEYVVRLSGRVRMRDE
SVRNNKMATGDIEVLGKELTILNEAETPPFELDAHSAAGEEVRLKYRYMDLRRPDVLKNFQFRSRLTHVVRAFLEGEGFM
DVETPILTRATPEGARDYLVPSRTHPGSFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
VEEEDIMGITERMVRSVFKELLSVDLPDFPRMPFSEAMQRFGSDKPDLRIALELIDIADLLAGVDFKVFSGPANDPKGRV
AAMRVPGGCSLSRKDIDGYTKFVSIYGAKGLAYIKVNDLAAGAEGLQSPILKFLTEDAIKGILERTGAETGDLIFFGADK
AKIVNEALGALRVKVGHDLNLVEGEWAPLWVVDFPMFEEDEGQYHALHHPFTMPSCSAEELKSNPGEALSRAYDMVLNGT
ELGGGSIRIHSPAMQRTVFEALGISDEEAEEKFGFLLDGLKYGAPPHGGLAFGLDRMVMLMTGCESIRDVIAFPKTQTAA
CTMTNAPSPVDNKQLREVGVQVRKEEG
>Mature_587_residues
MRSHYCGDLRASHDGETVELCGWVSRRRDHGGVIFLDLRDRNGLVQVVFDPDTVDAFALADKVRSEYVVRLSGRVRMRDE
SVRNNKMATGDIEVLGKELTILNEAETPPFELDAHSAAGEEVRLKYRYMDLRRPDVLKNFQFRSRLTHVVRAFLEGEGFM
DVETPILTRATPEGARDYLVPSRTHPGSFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
VEEEDIMGITERMVRSVFKELLSVDLPDFPRMPFSEAMQRFGSDKPDLRIALELIDIADLLAGVDFKVFSGPANDPKGRV
AAMRVPGGCSLSRKDIDGYTKFVSIYGAKGLAYIKVNDLAAGAEGLQSPILKFLTEDAIKGILERTGAETGDLIFFGADK
AKIVNEALGALRVKVGHDLNLVEGEWAPLWVVDFPMFEEDEGQYHALHHPFTMPSCSAEELKSNPGEALSRAYDMVLNGT
ELGGGSIRIHSPAMQRTVFEALGISDEEAEEKFGFLLDGLKYGAPPHGGLAFGLDRMVMLMTGCESIRDVIAFPKTQTAA
CTMTNAPSPVDNKQLREVGVQVRKEEG

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=601, Percent_Identity=39.6006655574043, Blast_Score=413, Evalue=1e-115,
Organism=Homo sapiens, GI5031815, Length=256, Percent_Identity=28.515625, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI194272210, Length=256, Percent_Identity=28.515625, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI45439306, Length=294, Percent_Identity=27.2108843537415, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1788173, Length=588, Percent_Identity=62.2448979591837, Blast_Score=762, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=275, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790571, Length=295, Percent_Identity=27.7966101694915, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32566633, Length=598, Percent_Identity=37.123745819398, Blast_Score=350, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI71994340, Length=252, Percent_Identity=27.3809523809524, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17535925, Length=252, Percent_Identity=27.3809523809524, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17535927, Length=252, Percent_Identity=27.3809523809524, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17551876, Length=278, Percent_Identity=23.7410071942446, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325153, Length=632, Percent_Identity=33.2278481012658, Blast_Score=293, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6323011, Length=258, Percent_Identity=27.906976744186, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320242, Length=257, Percent_Identity=24.5136186770428, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24584738, Length=604, Percent_Identity=36.7549668874172, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24640849, Length=262, Percent_Identity=27.8625954198473, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24640851, Length=262, Percent_Identity=27.8625954198473, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17136276, Length=262, Percent_Identity=25.5725190839695, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19921528, Length=274, Percent_Identity=28.1021897810219, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_ALCBS (Q0VRK1)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692469.1
- ProteinModelPortal:   Q0VRK1
- SMR:   Q0VRK1
- STRING:   Q0VRK1
- GeneID:   4213839
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0749
- NMPDR:   fig|393595.12.peg.752
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- PhylomeDB:   Q0VRK1
- BioCyc:   ABOR393595:ABO_0749-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 65331; Mature: 65331

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHYCGDLRASHDGETVELCGWVSRRRDHGGVIFLDLRDRNGLVQVVFDPDTVDAFALA
CCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHH
DKVRSEYVVRLSGRVRMRDESVRNNKMATGDIEVLGKELTILNEAETPPFELDAHSAAGE
HHHHHCEEEEECCCEEECCHHHCCCCCCCCHHHHHCCEEEEEECCCCCCCEECCCCCCCC
EVRLKYRYMDLRRPDVLKNFQFRSRLTHVVRAFLEGEGFMDVETPILTRATPEGARDYLV
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCCCCCCCC
PSRTHPGSFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
CCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHH
VEEEDIMGITERMVRSVFKELLSVDLPDFPRMPFSEAMQRFGSDKPDLRIALELIDIADL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHH
LAGVDFKVFSGPANDPKGRVAAMRVPGGCSLSRKDIDGYTKFVSIYGAKGLAYIKVNDLA
HHCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCHH
AGAEGLQSPILKFLTEDAIKGILERTGAETGDLIFFGADKAKIVNEALGALRVKVGHDLN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHEEEEECCCCE
LVEGEWAPLWVVDFPMFEEDEGQYHALHHPFTMPSCSAEELKSNPGEALSRAYDMVLNGT
EECCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCC
ELGGGSIRIHSPAMQRTVFEALGISDEEAEEKFGFLLDGLKYGAPPHGGLAFGLDRMVML
CCCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
MTGCESIRDVIAFPKTQTAACTMTNAPSPVDNKQLREVGVQVRKEEG
HHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHCHHHCCCCC
>Mature Secondary Structure
MRSHYCGDLRASHDGETVELCGWVSRRRDHGGVIFLDLRDRNGLVQVVFDPDTVDAFALA
CCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHH
DKVRSEYVVRLSGRVRMRDESVRNNKMATGDIEVLGKELTILNEAETPPFELDAHSAAGE
HHHHHCEEEEECCCEEECCHHHCCCCCCCCHHHHHCCEEEEEECCCCCCCEECCCCCCCC
EVRLKYRYMDLRRPDVLKNFQFRSRLTHVVRAFLEGEGFMDVETPILTRATPEGARDYLV
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCCCCCCCC
PSRTHPGSFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQIDLEASF
CCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHH
VEEEDIMGITERMVRSVFKELLSVDLPDFPRMPFSEAMQRFGSDKPDLRIALELIDIADL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHH
LAGVDFKVFSGPANDPKGRVAAMRVPGGCSLSRKDIDGYTKFVSIYGAKGLAYIKVNDLA
HHCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCHH
AGAEGLQSPILKFLTEDAIKGILERTGAETGDLIFFGADKAKIVNEALGALRVKVGHDLN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHEEEEECCCCE
LVEGEWAPLWVVDFPMFEEDEGQYHALHHPFTMPSCSAEELKSNPGEALSRAYDMVLNGT
EECCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCC
ELGGGSIRIHSPAMQRTVFEALGISDEEAEEKFGFLLDGLKYGAPPHGGLAFGLDRMVML
CCCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
MTGCESIRDVIAFPKTQTAACTMTNAPSPVDNKQLREVGVQVRKEEG
HHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA