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The map label for this gene is murX/mraY

Identifier: 110833456

GI number: 110833456

Start: 652413

End: 653495

Strand: Direct

Name: murX/mraY

Synonym: ABO_0595

Alternate gene names: 110833456

Gene position: 652413-653495 (Clockwise)

Preceding gene: 110833455

Following gene: 110833457

Centisome position: 20.91

GC content: 56.6

Gene sequence:

>1083_bases
ATGCTGCTTTGGCTGGCTGAATATCTTGCGCAATACCACAGCGGTTTTCTGGTGGTGCAGTACATCACTTTGCGCGGCAT
CTTAAGTGTTCTCACTGCTTTGTTCATCGCTTTTTGGGTCGGCCCGATCATGATCCGCATGCTGCAGGAAAAACAGGTGG
GTCAGGCGATCCGTGATGATGGCCCGAAGAGCCATCTGAGCAAGGCCGGCACCCCCACCATGGGCGGCGCGCTGATTCTG
GTGGCCATCGTTATTTCCACCTTGCTGTGGGGCGACCTGGAAAACCGTTTTGTATGGATCACCTTGGGTGTGTTGTTTGT
TTTCGGCGCCGTGGGCTGGGTGGATGACTGGCGCAAGGTGGTGGAAAAGAACCCGCGGGGCCTGCCTGCTCGCTGGAAAT
ATTTGTGGCTGTCTGTTGGTGCGCTCGGCGCTGGGTGCGCCTTGTTCTTCACCGCGCAGAGCCCGGTGGAAACCCAGTTG
ATCGTGCCGTTCTTCAAAAGCGTCGCCATCAATATGGGCTGGTTCTACATCGTGCTGACCTATTTTGTGATTAACGGTAC
CAGCAATGCGGTGAATCTCACCGACGGGCTGGATGGCCTGGCGATTATGCCCACCGTGCTGGTGGGCGGCGCTCTGGGCA
TTTTTGCTTACGCCGGTGGCCATGCCGAGTTCGCTACGTATTTGCAGATTCCCTATGTGGCGGGTGCCGGTGAGCTGGTG
ATTATTTCTGCTGCCCTGTGTGGGGCGGGGTTGGGCTTTCTCTGGTTCAACGCGTATCCCGCTCAGGTATTTATGGGTGA
TGTGGGCGCGCTGTCCTTGGGGGCAGTGCTCGGTGTGATGGCGGTGATCGTCCGCCAGGAAATTGTGCTTTTCATCATGG
GCGGTGTGTTCGTGATGGAAACGGTATCGGTGATGCTGCAGGTGGGTTCGTTCAAGCTCACCGGTCGGCGGATTTTCCGC
ATGGCGCCTATTCATCACCATTTTGAGCTGAAGGGGTGGCCGGAGCCGAAGATTATTGTGCGGTTCTGGATCATCACCGT
GATTCTTGTACTTGTGGGTCTGGCGACCCTGAAAATCCGATAG

Upstream 100 bases:

>100_bases
GTGGCACTGTGTTGGTGAAAGGGTCGCGCAGCGCCGGTATGGAAGCGGTGGTAAGGCTGTTGGCGACACAAGAACACACA
CTCACACAGGGGGCACGCTG

Downstream 100 bases:

>100_bases
GGGATTGAGTCAATTTATGGCGAAAGACGGGTTTGATCTGGTCATTGGCCTGGGTGTAACAGGCCGCTCCGTGATCCGCT
ATCTAACGGATCAGGGTATG

Product: phospho-N-acetylmuramoyl-pentapeptide-transferas e

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLLWLAEYLAQYHSGFLVVQYITLRGILSVLTALFIAFWVGPIMIRMLQEKQVGQAIRDDGPKSHLSKAGTPTMGGALIL
VAIVISTLLWGDLENRFVWITLGVLFVFGAVGWVDDWRKVVEKNPRGLPARWKYLWLSVGALGAGCALFFTAQSPVETQL
IVPFFKSVAINMGWFYIVLTYFVINGTSNAVNLTDGLDGLAIMPTVLVGGALGIFAYAGGHAEFATYLQIPYVAGAGELV
IISAALCGAGLGFLWFNAYPAQVFMGDVGALSLGAVLGVMAVIVRQEIVLFIMGGVFVMETVSVMLQVGSFKLTGRRIFR
MAPIHHHFELKGWPEPKIIVRFWIITVILVLVGLATLKIR

Sequences:

>Translated_360_residues
MLLWLAEYLAQYHSGFLVVQYITLRGILSVLTALFIAFWVGPIMIRMLQEKQVGQAIRDDGPKSHLSKAGTPTMGGALIL
VAIVISTLLWGDLENRFVWITLGVLFVFGAVGWVDDWRKVVEKNPRGLPARWKYLWLSVGALGAGCALFFTAQSPVETQL
IVPFFKSVAINMGWFYIVLTYFVINGTSNAVNLTDGLDGLAIMPTVLVGGALGIFAYAGGHAEFATYLQIPYVAGAGELV
IISAALCGAGLGFLWFNAYPAQVFMGDVGALSLGAVLGVMAVIVRQEIVLFIMGGVFVMETVSVMLQVGSFKLTGRRIFR
MAPIHHHFELKGWPEPKIIVRFWIITVILVLVGLATLKIR
>Mature_360_residues
MLLWLAEYLAQYHSGFLVVQYITLRGILSVLTALFIAFWVGPIMIRMLQEKQVGQAIRDDGPKSHLSKAGTPTMGGALIL
VAIVISTLLWGDLENRFVWITLGVLFVFGAVGWVDDWRKVVEKNPRGLPARWKYLWLSVGALGAGCALFFTAQSPVETQL
IVPFFKSVAINMGWFYIVLTYFVINGTSNAVNLTDGLDGLAIMPTVLVGGALGIFAYAGGHAEFATYLQIPYVAGAGELV
IISAALCGAGLGFLWFNAYPAQVFMGDVGALSLGAVLGVMAVIVRQEIVLFIMGGVFVMETVSVMLQVGSFKLTGRRIFR
MAPIHHHFELKGWPEPKIIVRFWIITVILVLVGLATLKIR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=64.7222222222222, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_ALCBS (Q0VS05)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692315.1
- STRING:   Q0VS05
- GeneID:   4211247
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0595
- NMPDR:   fig|393595.12.peg.593
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q0VS05
- BioCyc:   ABOR393595:ABO_0595-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 39340; Mature: 39340

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfbaadb4)-; HASH(0x10ceabb0)-; HASH(0x111f66f8)-; HASH(0xb06852c)-; HASH(0x11204d7c)-; HASH(0x10af1448)-; HASH(0xf88eef4)-; HASH(0x10c94848)-; HASH(0xf8e1ff0)-; HASH(0x11066ee8)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLWLAEYLAQYHSGFLVVQYITLRGILSVLTALFIAFWVGPIMIRMLQEKQVGQAIRDD
CHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPKSHLSKAGTPTMGGALILVAIVISTLLWGDLENRFVWITLGVLFVFGAVGWVDDWRKV
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
VEKNPRGLPARWKYLWLSVGALGAGCALFFTAQSPVETQLIVPFFKSVAINMGWFYIVLT
HHCCCCCCCHHHHHHEEEHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHH
YFVINGTSNAVNLTDGLDGLAIMPTVLVGGALGIFAYAGGHAEFATYLQIPYVAGAGELV
HHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECEECCCCCEE
IISAALCGAGLGFLWFNAYPAQVFMGDVGALSLGAVLGVMAVIVRQEIVLFIMGGVFVME
EEEHHHHHCCHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSVMLQVGSFKLTGRRIFRMAPIHHHFELKGWPEPKIIVRFWIITVILVLVGLATLKIR
HHHHHHHHCCEEECCHHHEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLLWLAEYLAQYHSGFLVVQYITLRGILSVLTALFIAFWVGPIMIRMLQEKQVGQAIRDD
CHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPKSHLSKAGTPTMGGALILVAIVISTLLWGDLENRFVWITLGVLFVFGAVGWVDDWRKV
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
VEKNPRGLPARWKYLWLSVGALGAGCALFFTAQSPVETQLIVPFFKSVAINMGWFYIVLT
HHCCCCCCCHHHHHHEEEHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHH
YFVINGTSNAVNLTDGLDGLAIMPTVLVGGALGIFAYAGGHAEFATYLQIPYVAGAGELV
HHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECEECCCCCEE
IISAALCGAGLGFLWFNAYPAQVFMGDVGALSLGAVLGVMAVIVRQEIVLFIMGGVFVME
EEEHHHHHCCHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSVMLQVGSFKLTGRRIFRMAPIHHHFELKGWPEPKIIVRFWIITVILVLVGLATLKIR
HHHHHHHHCCEEECCHHHEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA