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The map label for this gene is lytB

Identifier: 110833323

GI number: 110833323

Start: 502784

End: 503719

Strand: Direct

Name: lytB

Synonym: ABO_0462

Alternate gene names: 110833323

Gene position: 502784-503719 (Clockwise)

Preceding gene: 110833322

Following gene: 110833324

Centisome position: 16.11

GC content: 57.05

Gene sequence:

>936_bases
ATGCAAATTCGTCTCGCTAATCCCCGCGGTTTCTGTGCTGGCGTGGATCGTGCCATCGACATCGTCAATCGCGCCTTGGA
AGTGTTTGGGCCGCCGATCCATGTTCGTCACGAAGTGGTGCATAACCGCTATGTGGTGGAGGATTTACGCCAGCGCGGCG
CTGTGTTCGTGGAAGAGCTGCACGAAGTGCCGGACGATGCCATTGTCATTTTCAGTGCCCACGGTGTCTCCAAAGCGGTG
CAGGAAGAGGCCAAGCGTCGTCAGCTGCAGGTTTTCGATGCCACTTGCCCTCTGGTCACTAAGGTGCATATGGAAGTCAT
CCGTTATGCCCGCGAGGGACGCGAAAGCATCCTGATAGGCCATGCCGGTCACCCAGAAGTGGAAGGCACCATGGGGCAGT
ATGATAAATCCTATGGCGGTGATATCTATCTGGTGGAAGACGAAGCTGATGTGGTGGCCCTGACGGTGCGAGATGAAAGC
AAATTGGCTTTCGTGACCCAAACCACACTGAGTGTGGACGATACTGCCCGGGTCATTGATGCTCTGCGCCAGCGGTTCCC
GGCCATTATCGGCCCCAAACGCGAAGATATTTGTTACGCAACGACGAACCGGCAGGATGCCGTGCGGCAGTTGGCGCTGG
AATGCGGCCTGGTGTTGGTGGTTGGTTCGGTGAATAGCTCTAATTCCAACCGCCTGCGTGAGCTGGCCGAGCGCTGTGGT
GCGGAGGCTTATCTGATTGATGAGCCGTCCCAAATTGAAGCGAGCTGGCTGAAAGGCAAAGCCGCCGTCGGCGTCACCGC
CGGAGCTAGTGCGCCTGAAGATCTAGTACAACAGGTTATCGCTACCCTGAAAAACCTAGGCGGTGAGGATGCCGAAGAAA
TCCCCGGCCGCGAAGAAAATATCCGCTTCTCCATGCCCAAGGCGCTACGCCCGTAG

Upstream 100 bases:

>100_bases
GAAAAGAGGAACGTTCATGGTTAGGCGGACAAACAACGGGCCGGCGGAATGATTCTGGTTTTCCGCTGCCCATTATCCAC
AGTCAACCATCAGTTGAATT

Downstream 100 bases:

>100_bases
CGCTTGTCCTGCCTTTAGTACCGTTAACTCCTCGGCTTTATCTCTTAGCGCTTCAATATAAGCAATAAGCAAAAATTTGC
TTCAGTCTACGCTTGAAGTG

Product: LytB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MQIRLANPRGFCAGVDRAIDIVNRALEVFGPPIHVRHEVVHNRYVVEDLRQRGAVFVEELHEVPDDAIVIFSAHGVSKAV
QEEAKRRQLQVFDATCPLVTKVHMEVIRYAREGRESILIGHAGHPEVEGTMGQYDKSYGGDIYLVEDEADVVALTVRDES
KLAFVTQTTLSVDDTARVIDALRQRFPAIIGPKREDICYATTNRQDAVRQLALECGLVLVVGSVNSSNSNRLRELAERCG
AEAYLIDEPSQIEASWLKGKAAVGVTAGASAPEDLVQQVIATLKNLGGEDAEEIPGREENIRFSMPKALRP

Sequences:

>Translated_311_residues
MQIRLANPRGFCAGVDRAIDIVNRALEVFGPPIHVRHEVVHNRYVVEDLRQRGAVFVEELHEVPDDAIVIFSAHGVSKAV
QEEAKRRQLQVFDATCPLVTKVHMEVIRYAREGRESILIGHAGHPEVEGTMGQYDKSYGGDIYLVEDEADVVALTVRDES
KLAFVTQTTLSVDDTARVIDALRQRFPAIIGPKREDICYATTNRQDAVRQLALECGLVLVVGSVNSSNSNRLRELAERCG
AEAYLIDEPSQIEASWLKGKAAVGVTAGASAPEDLVQQVIATLKNLGGEDAEEIPGREENIRFSMPKALRP
>Mature_311_residues
MQIRLANPRGFCAGVDRAIDIVNRALEVFGPPIHVRHEVVHNRYVVEDLRQRGAVFVEELHEVPDDAIVIFSAHGVSKAV
QEEAKRRQLQVFDATCPLVTKVHMEVIRYAREGRESILIGHAGHPEVEGTMGQYDKSYGGDIYLVEDEADVVALTVRDES
KLAFVTQTTLSVDDTARVIDALRQRFPAIIGPKREDICYATTNRQDAVRQLALECGLVLVVGSVNSSNSNRLRELAERCG
AEAYLIDEPSQIEASWLKGKAAVGVTAGASAPEDLVQQVIATLKNLGGEDAEEIPGREENIRFSMPKALRP

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family

Homologues:

Organism=Escherichia coli, GI1786212, Length=310, Percent_Identity=68.7096774193548, Blast_Score=430, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISPH_ALCBS (Q0VSD8)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692182.1
- STRING:   Q0VSD8
- GeneID:   4211493
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0462
- NMPDR:   fig|393595.12.peg.461
- eggNOG:   COG0761
- HOGENOM:   HBG335228
- OMA:   HMQVARA
- PhylomeDB:   Q0VSD8
- BioCyc:   ABOR393595:ABO_0462-MONOMER
- HAMAP:   MF_00191
- InterPro:   IPR003451
- TIGRFAMs:   TIGR00216

Pfam domain/function: PF02401 LYTB

EC number: =1.17.1.2

Molecular weight: Translated: 34259; Mature: 34259

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRLANPRGFCAGVDRAIDIVNRALEVFGPPIHVRHEVVHNRYVVEDLRQRGAVFVEEL
CEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HEVPDDAIVIFSAHGVSKAVQEEAKRRQLQVFDATCPLVTKVHMEVIRYAREGRESILIG
HHCCCCEEEEEECCCHHHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
HAGHPEVEGTMGQYDKSYGGDIYLVEDEADVVALTVRDESKLAFVTQTTLSVDDTARVID
CCCCCCCCCCHHHCCCCCCCCEEEEECCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHH
ALRQRFPAIIGPKREDICYATTNRQDAVRQLALECGLVLVVGSVNSSNSNRLRELAERCG
HHHHHCCHHCCCCCCCEEEEECCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCC
AEAYLIDEPSQIEASWLKGKAAVGVTAGASAPEDLVQQVIATLKNLGGEDAEEIPGREEN
CCEEEECCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
IRFSMPKALRP
EEEECCCCCCC
>Mature Secondary Structure
MQIRLANPRGFCAGVDRAIDIVNRALEVFGPPIHVRHEVVHNRYVVEDLRQRGAVFVEEL
CEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HEVPDDAIVIFSAHGVSKAVQEEAKRRQLQVFDATCPLVTKVHMEVIRYAREGRESILIG
HHCCCCEEEEEECCCHHHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
HAGHPEVEGTMGQYDKSYGGDIYLVEDEADVVALTVRDESKLAFVTQTTLSVDDTARVID
CCCCCCCCCCHHHCCCCCCCCEEEEECCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHH
ALRQRFPAIIGPKREDICYATTNRQDAVRQLALECGLVLVVGSVNSSNSNRLRELAERCG
HHHHHCCHHCCCCCCCEEEEECCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCC
AEAYLIDEPSQIEASWLKGKAAVGVTAGASAPEDLVQQVIATLKNLGGEDAEEIPGREEN
CCEEEECCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
IRFSMPKALRP
EEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA