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The map label for this gene is fkpB [H]

Identifier: 110833322

GI number: 110833322

Start: 502188

End: 502658

Strand: Direct

Name: fkpB [H]

Synonym: ABO_0461

Alternate gene names: 110833322

Gene position: 502188-502658 (Clockwise)

Preceding gene: 110833321

Following gene: 110833323

Centisome position: 16.1

GC content: 54.56

Gene sequence:

>471_bases
ATGAGTGAGTTGCTTCGCGTAGGCCCGGAAACCCGGATTACGCTGCATTTTGCCGTGCGTCTGATGGATGGCACGGATCT
GGATTCTACCTTTGATGGCGAGCCTGCTTCTTTTGTATGGGGAGATGAATCTCTGCTGCCGGGTTTTGAAAATGCCATTC
GTGGGCTTAAAGCTGGCGATCGCCGCAGTGTTTTTCTTGAGGCGGCCAAGGCCTTCGGTGAGTACAACGAGCAGAATGTG
CAACATTTCACCCGTGACACCTTTGCCGAGCACGACTCTCTTGAGCCGGGTATGGTGCTGAGTTTTGCCGATGCGGGCGG
CGCTGAATTGCCAGGCGTCATCGGTAAGGTCGATGAGGAGTGGGTCACGGTGGATTTCAATCACCCTTTGGCAGGCCGCG
ATCTCACCTTCGAGGTGGAAATCATTAGTATTGAACGCCATGCTCCCGAGCAGCCTGTGACGCTCAATTGA

Upstream 100 bases:

>100_bases
CATTTTCCCGCTTTCAATATTGCCGACACCGCCATTACCCTTGGGGCCGCATTGATCCTGCTGGAAATGCTGCTGTCAGC
GAAAAGAGAGCGTAAAAATA

Downstream 100 bases:

>100_bases
CCGTTGCCGGTGGACAGCCGGCGGTGAAAAGAGGAACGTTCATGGTTAGGCGGACAAACAACGGGCCGGCGGAATGATTC
TGGTTTTCCGCTGCCCATTA

Product: peptidyl-prolyl isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSELLRVGPETRITLHFAVRLMDGTDLDSTFDGEPASFVWGDESLLPGFENAIRGLKAGDRRSVFLEAAKAFGEYNEQNV
QHFTRDTFAEHDSLEPGMVLSFADAGGAELPGVIGKVDEEWVTVDFNHPLAGRDLTFEVEIISIERHAPEQPVTLN

Sequences:

>Translated_156_residues
MSELLRVGPETRITLHFAVRLMDGTDLDSTFDGEPASFVWGDESLLPGFENAIRGLKAGDRRSVFLEAAKAFGEYNEQNV
QHFTRDTFAEHDSLEPGMVLSFADAGGAELPGVIGKVDEEWVTVDFNHPLAGRDLTFEVEIISIERHAPEQPVTLN
>Mature_155_residues
SELLRVGPETRITLHFAVRLMDGTDLDSTFDGEPASFVWGDESLLPGFENAIRGLKAGDRRSVFLEAAKAFGEYNEQNVQ
HFTRDTFAEHDSLEPGMVLSFADAGGAELPGVIGKVDEEWVTVDFNHPLAGRDLTFEVEIISIERHAPEQPVTLN

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786211, Length=146, Percent_Identity=39.7260273972603, Blast_Score=104, Evalue=2e-24,
Organism=Escherichia coli, GI1789748, Length=147, Percent_Identity=34.6938775510204, Blast_Score=86, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17245; Mature: 17114

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELLRVGPETRITLHFAVRLMDGTDLDSTFDGEPASFVWGDESLLPGFENAIRGLKAGD
CCCCHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCC
RRSVFLEAAKAFGEYNEQNVQHFTRDTFAEHDSLEPGMVLSFADAGGAELPGVIGKVDEE
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
WVTVDFNHPLAGRDLTFEVEIISIERHAPEQPVTLN
EEEEECCCCCCCCCEEEEEEEEEEECCCCCCCEECC
>Mature Secondary Structure 
SELLRVGPETRITLHFAVRLMDGTDLDSTFDGEPASFVWGDESLLPGFENAIRGLKAGD
CCCHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCC
RRSVFLEAAKAFGEYNEQNVQHFTRDTFAEHDSLEPGMVLSFADAGGAELPGVIGKVDEE
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
WVTVDFNHPLAGRDLTFEVEIISIERHAPEQPVTLN
EEEEECCCCCCCCCEEEEEEEEEEECCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2121716 [H]