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The map label for this gene is yfhM [H]

Identifier: 110833297

GI number: 110833297

Start: 477193

End: 478164

Strand: Direct

Name: yfhM [H]

Synonym: ABO_0436

Alternate gene names: 110833297

Gene position: 477193-478164 (Clockwise)

Preceding gene: 110833294

Following gene: 110833298

Centisome position: 15.29

GC content: 53.19

Gene sequence:

>972_bases
ATGGCCTTCACGCGAGAGCGACAAGTCAGTGCAAATGGGTTGGATTTCTTTGTGGCGGAGGCCGGTGTGGCCGGTTTGCC
GCTGGTGTTGTGCTTGCATGGTTTTCCGGAGTGTTGGGCCTCTTGGCGGTATCAGCTACCGGTGCTAGCTCAGTCTGGTT
ATTACGCGGTGGCACCGGATTTGCGTGGTTATGGTTTTACCGATGCCCCTAAAGACGTCGAGGCTTACCGGCAAAGTAAG
TTGGTTGAGGATGTGATGGCATTGATTCGGGTGCTGGGCTACGACAGTGCCATCCTAATAGGACATGACTGGGGGTGTGC
GCTGGCTTGGCAGGTCGCCCGTTGTTACCCGAAATCGATTAAGGCAGTTATCGGTATGTCGGTTCCCTATGGCGGCCCAG
CACCGGTGCCGCCCACGGCAGCCATGCGTAAGCTGTTTGAAGATCGATTTTTCTACATGCTGTATTTCCAGCAAACAGGT
TTGCCGGAGCAGGAACTTGAGGCGGATGTATCGCACAGCTTGCGTTGTATTTTTCATGCCTTATCCGCTGACGGCATTGC
GGACTTCAATGTGAAGCCGGACGATACCGGCTTTCTTCAGTCCATGCCCGTTCCTGAAGCCCAACCGCGTTGGATGCGAG
AGGAAGATCTGGCTTACTACGTGGAGCGTTTTGAGCACAGTGGTTTTACCGGCGCAATCAATTGGTACCGGTCCATGGAT
GCCTCCTGGGAGGAAAGTCGCAATGCCAGCAATTGGCAAATTCCCATGCCGATATTATTTATAGGAGGCTTGCAGGACCC
GGTCCTCATGTTTAGCCAGAAAGCGCTACAGCGTATGCCTGACTATATGCCGGACCTGCGCACGGTGATGCTGGATCAGT
GTGGTCATTGGATTCAGATGGAGCAGGCCTCTGAAGTTAATCGAGAGATCTTGGCGTTTTTGGAAGAAGTCGATGGCGAT
AAAATCGAATAA

Upstream 100 bases:

>100_bases
TCAAATTCAAGTATGTGTTATGCCAACAATAGCATTTTAGTGATGTCGGGTAAGTAGCCGCTTGACTGTTTGTTTCCCGG
CCTTGAATTAGGATATGAGT

Downstream 100 bases:

>100_bases
CAGTAACTTTCACAGGGTAGCCGAATTTCATCGCGCTTTTTCTTTGCCGGTGGAGCCGCAGCCAGTAGTGCCAGACGATG
CCACTGTGCGGTTGCGGTTG

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAFTRERQVSANGLDFFVAEAGVAGLPLVLCLHGFPECWASWRYQLPVLAQSGYYAVAPDLRGYGFTDAPKDVEAYRQSK
LVEDVMALIRVLGYDSAILIGHDWGCALAWQVARCYPKSIKAVIGMSVPYGGPAPVPPTAAMRKLFEDRFFYMLYFQQTG
LPEQELEADVSHSLRCIFHALSADGIADFNVKPDDTGFLQSMPVPEAQPRWMREEDLAYYVERFEHSGFTGAINWYRSMD
ASWEESRNASNWQIPMPILFIGGLQDPVLMFSQKALQRMPDYMPDLRTVMLDQCGHWIQMEQASEVNREILAFLEEVDGD
KIE

Sequences:

>Translated_323_residues
MAFTRERQVSANGLDFFVAEAGVAGLPLVLCLHGFPECWASWRYQLPVLAQSGYYAVAPDLRGYGFTDAPKDVEAYRQSK
LVEDVMALIRVLGYDSAILIGHDWGCALAWQVARCYPKSIKAVIGMSVPYGGPAPVPPTAAMRKLFEDRFFYMLYFQQTG
LPEQELEADVSHSLRCIFHALSADGIADFNVKPDDTGFLQSMPVPEAQPRWMREEDLAYYVERFEHSGFTGAINWYRSMD
ASWEESRNASNWQIPMPILFIGGLQDPVLMFSQKALQRMPDYMPDLRTVMLDQCGHWIQMEQASEVNREILAFLEEVDGD
KIE
>Mature_322_residues
AFTRERQVSANGLDFFVAEAGVAGLPLVLCLHGFPECWASWRYQLPVLAQSGYYAVAPDLRGYGFTDAPKDVEAYRQSKL
VEDVMALIRVLGYDSAILIGHDWGCALAWQVARCYPKSIKAVIGMSVPYGGPAPVPPTAAMRKLFEDRFFYMLYFQQTGL
PEQELEADVSHSLRCIFHALSADGIADFNVKPDDTGFLQSMPVPEAQPRWMREEDLAYYVERFEHSGFTGAINWYRSMDA
SWEESRNASNWQIPMPILFIGGLQDPVLMFSQKALQRMPDYMPDLRTVMLDQCGHWIQMEQASEVNREILAFLEEVDGDK
IE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=293, Percent_Identity=35.1535836177474, Blast_Score=204, Evalue=8e-53,
Organism=Homo sapiens, GI218777837, Length=316, Percent_Identity=30.6962025316456, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI218777840, Length=317, Percent_Identity=30.5993690851735, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI13376164, Length=317, Percent_Identity=30.5993690851735, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI145611434, Length=285, Percent_Identity=24.2105263157895, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=315, Percent_Identity=28.2539682539683, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562298, Length=310, Percent_Identity=27.4193548387097, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324392, Length=113, Percent_Identity=30.9734513274336, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 36607; Mature: 36476

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFTRERQVSANGLDFFVAEAGVAGLPLVLCLHGFPECWASWRYQLPVLAQSGYYAVAPD
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHCCEECCEEEECCCCEEECCC
LRGYGFTDAPKDVEAYRQSKLVEDVMALIRVLGYDSAILIGHDWGCALAWQVARCYPKSI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
KAVIGMSVPYGGPAPVPPTAAMRKLFEDRFFYMLYFQQTGLPEQELEADVSHSLRCIFHA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LSADGIADFNVKPDDTGFLQSMPVPEAQPRWMREEDLAYYVERFEHSGFTGAINWYRSMD
HCCCCCEECCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCC
ASWEESRNASNWQIPMPILFIGGLQDPVLMFSQKALQRMPDYMPDLRTVMLDQCGHWIQM
CCHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEH
EQASEVNREILAFLEEVDGDKIE
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AFTRERQVSANGLDFFVAEAGVAGLPLVLCLHGFPECWASWRYQLPVLAQSGYYAVAPD
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHCCEECCEEEECCCCEEECCC
LRGYGFTDAPKDVEAYRQSKLVEDVMALIRVLGYDSAILIGHDWGCALAWQVARCYPKSI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
KAVIGMSVPYGGPAPVPPTAAMRKLFEDRFFYMLYFQQTGLPEQELEADVSHSLRCIFHA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LSADGIADFNVKPDDTGFLQSMPVPEAQPRWMREEDLAYYVERFEHSGFTGAINWYRSMD
HCCCCCEECCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCC
ASWEESRNASNWQIPMPILFIGGLQDPVLMFSQKALQRMPDYMPDLRTVMLDQCGHWIQM
CCHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEH
EQASEVNREILAFLEEVDGDKIE
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]