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The map label for this gene is gpmA

Identifier: 110635917

GI number: 110635917

Start: 3872542

End: 3873162

Strand: Reverse

Name: gpmA

Synonym: Meso_3591

Alternate gene names: 110635917

Gene position: 3873162-3872542 (Counterclockwise)

Preceding gene: 110635918

Following gene: 110635911

Centisome position: 87.78

GC content: 61.67

Gene sequence:

>621_bases
ATGTCCGGAACGCTGATCCTTGTTCGCCACGGCCAGAGCGAATGGAACCTGAAGAACCTGTTCACCGGCTGGCGCGATCC
CGGCCTATCCGAGCTTGGCCATGAAGAAGCCACATCGGCGGGACGCAAGATCAAGGACAGGGGGCTTAGACCGGACATCG
CCTTCACCTCGGTGCTTTCGCGCGCCAAAGTCACCAATACGCATATTCTGGAGGTCCTCGGATTGCCCGCTCTGGAGACG
ATCGAGGACGTGGCGCTCAACGAGCGGGATTACGGCGATCTCTCTGGCCTCAACAAGGACGACGCGCGAAAGAAATGGGG
CGAGGAGCAGGTGCATATCTGGCGCCGCTCTTATGATATTCCGCCTCCCGGCGGCGAGAGCCTGCGCGACACGGGTGCCC
GCGTCTGGCCCTACTATTTGCGGGAAATCCTCCCGCAGGTGCTGCGGGGCAAGACAGTGCTGGTGAGCGCTCACGGCAAT
TCGCTACGCTCGCTGGCGATGGTTCTGGACGGGCTTTCCGGCGAGGAGATCGTCAAGATGGAGATCGCCACAGGCGTTCC
GATCGTCTACCGGCTCAACCCCGATTCTACCGTGGCGTCGAAGGAGATCCTGGAGGGCTGA

Upstream 100 bases:

>100_bases
GGCCGCGCTCTGGGCGCGCGGCAGGAAGCCGGGCCTCCACTCCATGCTCGATGTACTGGGCTTCACCGAAAATTCCGACC
AAGCCAGATAGGGAAGAACC

Downstream 100 bases:

>100_bases
TGCGCCGCAGCCCGTCTGCGGTGCACGGGGTCTCAAACGGACCCATCTAGTTCAGCGGAGCCGGATGCACGAAGGGCCAG
GGCGATGCCTCCGAGCCACG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSGTLILVRHGQSEWNLKNLFTGWRDPGLSELGHEEATSAGRKIKDRGLRPDIAFTSVLSRAKVTNTHILEVLGLPALET
IEDVALNERDYGDLSGLNKDDARKKWGEEQVHIWRRSYDIPPPGGESLRDTGARVWPYYLREILPQVLRGKTVLVSAHGN
SLRSLAMVLDGLSGEEIVKMEIATGVPIVYRLNPDSTVASKEILEG

Sequences:

>Translated_206_residues
MSGTLILVRHGQSEWNLKNLFTGWRDPGLSELGHEEATSAGRKIKDRGLRPDIAFTSVLSRAKVTNTHILEVLGLPALET
IEDVALNERDYGDLSGLNKDDARKKWGEEQVHIWRRSYDIPPPGGESLRDTGARVWPYYLREILPQVLRGKTVLVSAHGN
SLRSLAMVLDGLSGEEIVKMEIATGVPIVYRLNPDSTVASKEILEG
>Mature_205_residues
SGTLILVRHGQSEWNLKNLFTGWRDPGLSELGHEEATSAGRKIKDRGLRPDIAFTSVLSRAKVTNTHILEVLGLPALETI
EDVALNERDYGDLSGLNKDDARKKWGEEQVHIWRRSYDIPPPGGESLRDTGARVWPYYLREILPQVLRGKTVLVSAHGNS
LRSLAMVLDGLSGEEIVKMEIATGVPIVYRLNPDSTVASKEILEG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=218, Percent_Identity=44.4954128440367, Blast_Score=175, Evalue=3e-44,
Organism=Homo sapiens, GI4505753, Length=218, Percent_Identity=44.4954128440367, Blast_Score=174, Evalue=4e-44,
Organism=Homo sapiens, GI71274132, Length=218, Percent_Identity=42.2018348623853, Blast_Score=163, Evalue=1e-40,
Organism=Homo sapiens, GI4502445, Length=220, Percent_Identity=40, Blast_Score=154, Evalue=6e-38,
Organism=Homo sapiens, GI40353764, Length=220, Percent_Identity=40, Blast_Score=154, Evalue=6e-38,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=43.125, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI1786970, Length=216, Percent_Identity=42.5925925925926, Blast_Score=161, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322697, Length=214, Percent_Identity=42.5233644859813, Blast_Score=159, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6320183, Length=270, Percent_Identity=28.1481481481481, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324516, Length=265, Percent_Identity=28.3018867924528, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI85725270, Length=219, Percent_Identity=43.8356164383562, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI85725272, Length=219, Percent_Identity=43.8356164383562, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24650981, Length=219, Percent_Identity=43.8356164383562, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24646216, Length=217, Percent_Identity=41.4746543778802, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=35.4545454545455, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=35.4545454545455, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=35.4545454545455, Blast_Score=124, Evalue=4e-29,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_MESSB (Q11CB5)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_676125.1
- ProteinModelPortal:   Q11CB5
- SMR:   Q11CB5
- STRING:   Q11CB5
- GeneID:   4182190
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3591
- NMPDR:   fig|266779.1.peg.945
- eggNOG:   COG0588
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- PhylomeDB:   Q11CB5
- ProtClustDB:   PRK01295
- BioCyc:   MSP266779:MESO_3591-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 22849; Mature: 22718

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 10-10 ACT_SITE 158-158

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTLILVRHGQSEWNLKNLFTGWRDPGLSELGHEEATSAGRKIKDRGLRPDIAFTSVLS
CCCCEEEEECCCCCCCHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHH
RAKVTNTHILEVLGLPALETIEDVALNERDYGDLSGLNKDDARKKWGEEQVHIWRRSYDI
HHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCC
PPPGGESLRDTGARVWPYYLREILPQVLRGKTVLVSAHGNSLRSLAMVLDGLSGEEIVKM
CCCCCCCHHHCCCEECHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEE
EIATGVPIVYRLNPDSTVASKEILEG
EECCCCEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
SGTLILVRHGQSEWNLKNLFTGWRDPGLSELGHEEATSAGRKIKDRGLRPDIAFTSVLS
CCCEEEEECCCCCCCHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHH
RAKVTNTHILEVLGLPALETIEDVALNERDYGDLSGLNKDDARKKWGEEQVHIWRRSYDI
HHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCC
PPPGGESLRDTGARVWPYYLREILPQVLRGKTVLVSAHGNSLRSLAMVLDGLSGEEIVKM
CCCCCCCHHHCCCEECHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEE
EIATGVPIVYRLNPDSTVASKEILEG
EECCCCEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA