Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 110635918

GI number: 110635918

Start: 3873172

End: 3874005

Strand: Reverse

Name: dapB

Synonym: Meso_3592

Alternate gene names: 110635918

Gene position: 3874005-3873172 (Counterclockwise)

Preceding gene: 110635919

Following gene: 110635917

Centisome position: 87.8

GC content: 64.39

Gene sequence:

>834_bases
ATGAATGATATGGGACTCGTAATCGTTGGCGCTGGCGGGCGAATGGGCCAGACGCTCATACGCACCGTTCATGCCATGGA
GGGCGTTCGGGTCGTCGGCGCCATCGAGCGTTCCGGCTCGCCCCATCTTGGCCGAGACGCAGGCGAACTCGCCGGCATCG
GCATCATCAATGTGGAGATCTGCGACGAGCCGCTATCGGTCTTCGCCAAGGCCGATGGGGTGCTGGATTTCACCACACCG
AAAGCAACGGTGGAATTCGCGGGGTACGCCGCTCAGGCCCGCATCGTCCATGTGATCGGCACGACGGGGCTTTCCGGCGA
AGACGAGGCAGCGATCGCCGCGGCCGCCCGGCATGCCACGATTGTGAAATCAGGCAATATGAGCCTCGGGGTCAACCTGC
TTTCCGTTCTGGTGAAGCAGGCGGCCAGGGCGCTGGATGCGGCCGATTTCGACATCGAGATTCTTGAGATGCATCATCGC
CATAAGGTGGATGCGCCTTCAGGAACAGCGCTGCTGCTGGGCGAGGCGGCGGCGGAAGGGCGCGCCATCGAACTGGCGGA
CAAGAGCGTTCGCGTGCGCGACGGCCATACCGGCCCGCGCGAAGCCGGCACCATCGGGTTCGCCACGCTTCGCGGTGGCT
CCGTCGTGGGGGAGCATTCGGTCATCCTCGCCGGCATCGGTGAACGCATCGTCCTTTCGCATCTTGCCGAAGATCGCACC
ATCTTCGCGCGCGGCGCCGTCAAGGCCGCGCTCTGGGCGCGCGGCAGGAAGCCGGGCCTCCACTCCATGCTCGATGTACT
GGGCTTCACCGAAAATTCCGACCAAGCCAGATAG

Upstream 100 bases:

>100_bases
GCTTCTATCGCATGCAGACGGAACGGGCGGAGAACCTCCTGGAAGGTGGGGAAGTGGATACCAACGATGCCACCATGGAG
CAGATAAGGGGTGGTCGCCG

Downstream 100 bases:

>100_bases
GGAAGAACCATGTCCGGAACGCTGATCCTTGTTCGCCACGGCCAGAGCGAATGGAACCTGAAGAACCTGTTCACCGGCTG
GCGCGATCCCGGCCTATCCG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MNDMGLVIVGAGGRMGQTLIRTVHAMEGVRVVGAIERSGSPHLGRDAGELAGIGIINVEICDEPLSVFAKADGVLDFTTP
KATVEFAGYAAQARIVHVIGTTGLSGEDEAAIAAAARHATIVKSGNMSLGVNLLSVLVKQAARALDAADFDIEILEMHHR
HKVDAPSGTALLLGEAAAEGRAIELADKSVRVRDGHTGPREAGTIGFATLRGGSVVGEHSVILAGIGERIVLSHLAEDRT
IFARGAVKAALWARGRKPGLHSMLDVLGFTENSDQAR

Sequences:

>Translated_277_residues
MNDMGLVIVGAGGRMGQTLIRTVHAMEGVRVVGAIERSGSPHLGRDAGELAGIGIINVEICDEPLSVFAKADGVLDFTTP
KATVEFAGYAAQARIVHVIGTTGLSGEDEAAIAAAARHATIVKSGNMSLGVNLLSVLVKQAARALDAADFDIEILEMHHR
HKVDAPSGTALLLGEAAAEGRAIELADKSVRVRDGHTGPREAGTIGFATLRGGSVVGEHSVILAGIGERIVLSHLAEDRT
IFARGAVKAALWARGRKPGLHSMLDVLGFTENSDQAR
>Mature_277_residues
MNDMGLVIVGAGGRMGQTLIRTVHAMEGVRVVGAIERSGSPHLGRDAGELAGIGIINVEICDEPLSVFAKADGVLDFTTP
KATVEFAGYAAQARIVHVIGTTGLSGEDEAAIAAAARHATIVKSGNMSLGVNLLSVLVKQAARALDAADFDIEILEMHHR
HKVDAPSGTALLLGEAAAEGRAIELADKSVRVRDGHTGPREAGTIGFATLRGGSVVGEHSVILAGIGERIVLSHLAEDRT
IFARGAVKAALWARGRKPGLHSMLDVLGFTENSDQAR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=263, Percent_Identity=48.2889733840304, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_MESSB (Q11CB4)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_676126.1
- ProteinModelPortal:   Q11CB4
- SMR:   Q11CB4
- STRING:   Q11CB4
- GeneID:   4182191
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3592
- NMPDR:   fig|266779.1.peg.944
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   Q11CB4
- ProtClustDB:   PRK00048
- BioCyc:   MSP266779:MESO_3592-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28796; Mature: 28796

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDMGLVIVGAGGRMGQTLIRTVHAMEGVRVVGAIERSGSPHLGRDAGELAGIGIINVEI
CCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHCEEEEEEEE
CDEPLSVFAKADGVLDFTTPKATVEFAGYAAQARIVHVIGTTGLSGEDEAAIAAAARHAT
CCCHHHHHHHCCCEEEECCCCCEEEECCEEECEEEEEEEECCCCCCCCCHHHHHHHHHEE
IVKSGNMSLGVNLLSVLVKQAARALDAADFDIEILEMHHRHKVDAPSGTALLLGEAAAEG
EEECCCCEEHHHHHHHHHHHHHHHHCCCCCCHHEEEHHHHCCCCCCCCCEEEEECCCCCC
RAIELADKSVRVRDGHTGPREAGTIGFATLRGGSVVGEHSVILAGIGERIVLSHLAEDRT
CEEEEECCEEEEECCCCCCCCCCCEEEEEECCCCEECCCCEEEECCCHHHHHHHHHCCCE
IFARGAVKAALWARGRKPGLHSMLDVLGFTENSDQAR
EEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNDMGLVIVGAGGRMGQTLIRTVHAMEGVRVVGAIERSGSPHLGRDAGELAGIGIINVEI
CCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHCEEEEEEEE
CDEPLSVFAKADGVLDFTTPKATVEFAGYAAQARIVHVIGTTGLSGEDEAAIAAAARHAT
CCCHHHHHHHCCCEEEECCCCCEEEECCEEECEEEEEEEECCCCCCCCCHHHHHHHHHEE
IVKSGNMSLGVNLLSVLVKQAARALDAADFDIEILEMHHRHKVDAPSGTALLLGEAAAEG
EEECCCCEEHHHHHHHHHHHHHHHHCCCCCCHHEEEHHHHCCCCCCCCCEEEEECCCCCC
RAIELADKSVRVRDGHTGPREAGTIGFATLRGGSVVGEHSVILAGIGERIVLSHLAEDRT
CEEEEECCEEEEECCCCCCCCCCCEEEEEECCCCEECCCCEEEECCCHHHHHHHHHCCCE
IFARGAVKAALWARGRKPGLHSMLDVLGFTENSDQAR
EEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA