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The map label for this gene is hslV

Identifier: 110635820

GI number: 110635820

Start: 3766057

End: 3766605

Strand: Reverse

Name: hslV

Synonym: Meso_3492

Alternate gene names: 110635820

Gene position: 3766605-3766057 (Counterclockwise)

Preceding gene: 110635828

Following gene: 110635819

Centisome position: 85.36

GC content: 61.93

Gene sequence:

>549_bases
ATGAGCGATAATCTGACAATGCACGGAACCACCATTGTCACCGTTCGGAAGGGCGGGAAGGTCGTGATTGCCGGCGACGG
ACAGGTGAGCCTCGGACAAACCGTTATGAAGGGCAACGCCCGGAAGGTGCGCCGGATCGGCAAGGGCAATGTGATCGCAG
GCTTCGCGGGGGCGACGGCCGATGCTTTCACGCTGCTCGAAAGGCTGGAGAAGAAGCTGGAGCAGTATCCCGACCAGCTC
ATGCGGGCGAGCGTGGAGCTGGCAAAGGACTGGCGGACGGACCGCTATTTGCGTCGGCTGGAGGCAATGATGCTCGTGGC
CGACAAGAACGTGACGCTGGCGCTCACCGGAACCGGCGATGTGCTGGAGCCGGAAGAGGGGGTGATGGCAATCGGGTCGG
GCGGGAATTATGCGCTCGCGGCCGCACGCGCGCTTATCGACACGGACAAGAGCGCGGAGGAGATTGCCCGCAAGGCGATG
GAGATTGCCGCAAGCATCTGCGTCTACACAAACAGCAATATCATCGTGGAAACGCTGGATGCCGGCTGA

Upstream 100 bases:

>100_bases
CGGGGAGATCATGAACCCGCGGCATTTGCATTCCTTTGCCTGTCTCTTACATAAACGCTCGAAACGGCGCCCGCGAGAGG
CGTCCAGGAGCAAAATTTCC

Downstream 100 bases:

>100_bases
GCCCACCATCCGCTTCGAGCCGGTCACGGCGGAGCATCTGCCGATGCTTCGCCACTGGTTGAAGCAGCCGCATATGCGGG
AATGGTGGGGCGAACCTGAG

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MSDNLTMHGTTIVTVRKGGKVVIAGDGQVSLGQTVMKGNARKVRRIGKGNVIAGFAGATADAFTLLERLEKKLEQYPDQL
MRASVELAKDWRTDRYLRRLEAMMLVADKNVTLALTGTGDVLEPEEGVMAIGSGGNYALAAARALIDTDKSAEEIARKAM
EIAASICVYTNSNIIVETLDAG

Sequences:

>Translated_182_residues
MSDNLTMHGTTIVTVRKGGKVVIAGDGQVSLGQTVMKGNARKVRRIGKGNVIAGFAGATADAFTLLERLEKKLEQYPDQL
MRASVELAKDWRTDRYLRRLEAMMLVADKNVTLALTGTGDVLEPEEGVMAIGSGGNYALAAARALIDTDKSAEEIARKAM
EIAASICVYTNSNIIVETLDAG
>Mature_181_residues
SDNLTMHGTTIVTVRKGGKVVIAGDGQVSLGQTVMKGNARKVRRIGKGNVIAGFAGATADAFTLLERLEKKLEQYPDQLM
RASVELAKDWRTDRYLRRLEAMMLVADKNVTLALTGTGDVLEPEEGVMAIGSGGNYALAAARALIDTDKSAEEIARKAME
IAASICVYTNSNIIVETLDAG

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=61.9883040935673, Blast_Score=213, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_MESSB (Q11CL2)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_676028.1
- ProteinModelPortal:   Q11CL2
- SMR:   Q11CL2
- STRING:   Q11CL2
- MEROPS:   T01.006
- GeneID:   4182152
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3492
- NMPDR:   fig|266779.1.peg.1042
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   Q11CL2
- ProtClustDB:   PRK05456
- BioCyc:   MSP266779:MESO_3492-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19460; Mature: 19328

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: ACT_SITE 10-10

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNLTMHGTTIVTVRKGGKVVIAGDGQVSLGQTVMKGNARKVRRIGKGNVIAGFAGATA
CCCCEEECCEEEEEEECCCEEEEEECCCCCCCHHHHCCCHHHHHHCCCCCEEEEECCCCH
DAFTLLERLEKKLEQYPDQLMRASVELAKDWRTDRYLRRLEAMMLVADKNVTLALTGTGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCEEEEEECCCC
VLEPEEGVMAIGSGGNYALAAARALIDTDKSAEEIARKAMEIAASICVYTNSNIIVETLD
CCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEEEC
AG
CC
>Mature Secondary Structure 
SDNLTMHGTTIVTVRKGGKVVIAGDGQVSLGQTVMKGNARKVRRIGKGNVIAGFAGATA
CCCEEECCEEEEEEECCCEEEEEECCCCCCCHHHHCCCHHHHHHCCCCCEEEEECCCCH
DAFTLLERLEKKLEQYPDQLMRASVELAKDWRTDRYLRRLEAMMLVADKNVTLALTGTGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCEEEEEECCCC
VLEPEEGVMAIGSGGNYALAAARALIDTDKSAEEIARKAMEIAASICVYTNSNIIVETLD
CCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEEEC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA