Click here to switch to the map view.

The map label for this gene is cbbT [H]

Identifier: 110635768

GI number: 110635768

Start: 3719592

End: 3721652

Strand: Reverse

Name: cbbT [H]

Synonym: Meso_3440

Alternate gene names: 110635768

Gene position: 3721652-3719592 (Counterclockwise)

Preceding gene: 110635777

Following gene: 110635767

Centisome position: 84.34

GC content: 61.48

Gene sequence:

>2061_bases
ATGTGTCGCCTGCTTTTGCGGGCGCGAGCCCCGCCAGTGCCCGACAGACCGCAGCCGACCCAGCGAGCGCACATGATCTC
ACGCGAAAAACACGACCGGATGGCGAATGCGATCCGTTTCCTTTCGATGGATGCCGTCGAAAAGGCCAAGTCCGGACATC
CGGGCCTTCCCATGGGGACGGCTGACATTGCGACAGTCCTTTTCACGCGGTTCATGAAACATGACCCGAAGACGCCCCAT
TGGCCGGATCGCGATCGCTTCGTCCTTTCGGCGGGCCACGGCTCGATGCTGCTTTACTCGCTGCTCCACCTGCTGGGCTA
CGAGGACATCACAATCGAGGAAATCAAGAATTTCCGCCAGCTCGGCTCGCGTACGGCAGGTCATCCCGAATATGGCTTCG
CTGCCGGCATCGAGACGACGACCGGCCCTCTCGGCCAGGGCTTCGGCAATGCCGTGGGCATGGCGATCGCCGAGCGTCTG
CTCAACGCCCGCTACGGTGACGACCTTGTCAATCACTTTACCTATGCCCTGGTAGGCGATGGCTGTCTGATGGAAGGCAT
CAGCCAGGAGGCCTTGACGCTCGCCGGCCACCTCAGGCTCAACAAGCTAATCGTCCTCTTCGACGATAACCATATCTCCA
TTGACGGCCCTGTCTCGCTTGCCGATTCCACCGATCAGTGCGCGCGCTTTGCCGCTTCGGGCTGGAATACGCTGCGCGCC
GACGGGCATGATCCCGACGCGATCGCTTCGGCCATCGAGACTGCGCGCCAGTCCGATCGGCCGACGCTGATCGCCTTCCG
CACCACTATCGGCTACGGCTCGCCGAGCAAAGCCGGCACGAACAAGGTGCATGGCTCTCCTCTCGGCGCCGACGAGATCG
CCAAGACACGCTCAGCTCTCGGCTGGGATTCACCCCCCTTTGTTGTACCGTCTGAGGTTCTAGACGACTGGCGGCTGGCC
GGCCTTCGCTCGGCCAAAGAGCGTGGCTCGTGGGAAAAGCGCCTTGCCGCCGCCGATACCGAGACGCGCGCGCAGTTCGA
GCGGCGCATGCGCGGCGATCTCCCGGCGGCCTTTCCGGGCGTCATCGTCGATTACAAGAAAAAGCTGGCGCAGCAGAATA
CCGCCGTTGCTACCCGAAACGCTTCCGAGATGGCGCTTGAGGTGATCAACGATTGTATTCCCGAGACGGTGGGTGGCTCC
GCCGACCTGACTGGCTCCAACAACACCAAAACGAGCCAGACGACTCCAATCACGCCTACGGACTTTTCAGGCCGCTACAT
ACATTTCGGCATTCGCGAGCACGCGATGGCGGCCGCCATGAACGGAATTGCCTTGCATGGCGGTTTGATCCCTTACGGCG
GCACCTTTCTGACTTTCTCCGATTATGCCCGGCCGGCCATGCGGCTTGCTTCCTTGATGCATATTCGTTCCATCTTCGTC
ATGACGCACGATTCCATCGGTCTCGGCGAGGACGGCCCAACGCATCAACCGGTCGAGCATCTGGCTGCCCTGCGCGCTAT
CCCGAATCACAATGTTTTCCGTCCCGCGGATGCTACGGAAACCGCTGAATGCTGGCAGCTTGCCCTTGAATCGAGGAAGA
CGCCCTCCACCATCGCCTTGACGCGCCAGAAACTTCAGCCCGTGCGCCTTGAATTCGAGGAGGAGAACCTGTGTGCCCGC
GGAGCTTACGAACTTCTGCCCGCCAGCGACGAAGCGAAGGTGACAATCTTCGCCAGCGGCTCGGAAGTGGAAATCGCCGT
AAAGGCTCGTGTCATGCTCGAAGAGCGGGGATACCCCACGCGCGTCGTCTCGGTGCCCTGTTTCGAGCTGTTTGAAGAGC
AGTCGCAGGATTATCAGCGGGCGATTCTTGGTGATGCTCCGGTGCGGATTGCCATTGAGGCCGGCGTGCGGCAGGGTTGG
GATCGCTTTATTGGCGTCGATGGCATCTTCATCGGCATGCACGGCTTTGGTGCCAGCGGACCCGCGCCCGAGCTCTACCA
GCATTTCGGCATCACCGCCGAAGCTGCTGTTGAGGCGGTGGAGGCGCGACTGCCCGATTGA

Upstream 100 bases:

>100_bases
TTTGCTGGCCAAGAGAAGAGGTTTCTCGAAAAATGGAGGCTGGTAAGGGGCGAACCTTTCCGATGTGCGGCTGTTTATTG
ACTTGAGCAACGCAACTGCT

Downstream 100 bases:

>100_bases
GAAATTTGCGCCGGGAGGCGCAGTCGGTTTTTTAGCGGACGCCGCCGCGAAATCGGCGTCCAGCTATGCTTCCATGTATC
GTGTCACGCTCGCCGGAGGT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MCRLLLRARAPPVPDRPQPTQRAHMISREKHDRMANAIRFLSMDAVEKAKSGHPGLPMGTADIATVLFTRFMKHDPKTPH
WPDRDRFVLSAGHGSMLLYSLLHLLGYEDITIEEIKNFRQLGSRTAGHPEYGFAAGIETTTGPLGQGFGNAVGMAIAERL
LNARYGDDLVNHFTYALVGDGCLMEGISQEALTLAGHLRLNKLIVLFDDNHISIDGPVSLADSTDQCARFAASGWNTLRA
DGHDPDAIASAIETARQSDRPTLIAFRTTIGYGSPSKAGTNKVHGSPLGADEIAKTRSALGWDSPPFVVPSEVLDDWRLA
GLRSAKERGSWEKRLAAADTETRAQFERRMRGDLPAAFPGVIVDYKKKLAQQNTAVATRNASEMALEVINDCIPETVGGS
ADLTGSNNTKTSQTTPITPTDFSGRYIHFGIREHAMAAAMNGIALHGGLIPYGGTFLTFSDYARPAMRLASLMHIRSIFV
MTHDSIGLGEDGPTHQPVEHLAALRAIPNHNVFRPADATETAECWQLALESRKTPSTIALTRQKLQPVRLEFEEENLCAR
GAYELLPASDEAKVTIFASGSEVEIAVKARVMLEERGYPTRVVSVPCFELFEEQSQDYQRAILGDAPVRIAIEAGVRQGW
DRFIGVDGIFIGMHGFGASGPAPELYQHFGITAEAAVEAVEARLPD

Sequences:

>Translated_686_residues
MCRLLLRARAPPVPDRPQPTQRAHMISREKHDRMANAIRFLSMDAVEKAKSGHPGLPMGTADIATVLFTRFMKHDPKTPH
WPDRDRFVLSAGHGSMLLYSLLHLLGYEDITIEEIKNFRQLGSRTAGHPEYGFAAGIETTTGPLGQGFGNAVGMAIAERL
LNARYGDDLVNHFTYALVGDGCLMEGISQEALTLAGHLRLNKLIVLFDDNHISIDGPVSLADSTDQCARFAASGWNTLRA
DGHDPDAIASAIETARQSDRPTLIAFRTTIGYGSPSKAGTNKVHGSPLGADEIAKTRSALGWDSPPFVVPSEVLDDWRLA
GLRSAKERGSWEKRLAAADTETRAQFERRMRGDLPAAFPGVIVDYKKKLAQQNTAVATRNASEMALEVINDCIPETVGGS
ADLTGSNNTKTSQTTPITPTDFSGRYIHFGIREHAMAAAMNGIALHGGLIPYGGTFLTFSDYARPAMRLASLMHIRSIFV
MTHDSIGLGEDGPTHQPVEHLAALRAIPNHNVFRPADATETAECWQLALESRKTPSTIALTRQKLQPVRLEFEEENLCAR
GAYELLPASDEAKVTIFASGSEVEIAVKARVMLEERGYPTRVVSVPCFELFEEQSQDYQRAILGDAPVRIAIEAGVRQGW
DRFIGVDGIFIGMHGFGASGPAPELYQHFGITAEAAVEAVEARLPD
>Mature_686_residues
MCRLLLRARAPPVPDRPQPTQRAHMISREKHDRMANAIRFLSMDAVEKAKSGHPGLPMGTADIATVLFTRFMKHDPKTPH
WPDRDRFVLSAGHGSMLLYSLLHLLGYEDITIEEIKNFRQLGSRTAGHPEYGFAAGIETTTGPLGQGFGNAVGMAIAERL
LNARYGDDLVNHFTYALVGDGCLMEGISQEALTLAGHLRLNKLIVLFDDNHISIDGPVSLADSTDQCARFAASGWNTLRA
DGHDPDAIASAIETARQSDRPTLIAFRTTIGYGSPSKAGTNKVHGSPLGADEIAKTRSALGWDSPPFVVPSEVLDDWRLA
GLRSAKERGSWEKRLAAADTETRAQFERRMRGDLPAAFPGVIVDYKKKLAQQNTAVATRNASEMALEVINDCIPETVGGS
ADLTGSNNTKTSQTTPITPTDFSGRYIHFGIREHAMAAAMNGIALHGGLIPYGGTFLTFSDYARPAMRLASLMHIRSIFV
MTHDSIGLGEDGPTHQPVEHLAALRAIPNHNVFRPADATETAECWQLALESRKTPSTIALTRQKLQPVRLEFEEENLCAR
GAYELLPASDEAKVTIFASGSEVEIAVKARVMLEERGYPTRVVSVPCFELFEEQSQDYQRAILGDAPVRIAIEAGVRQGW
DRFIGVDGIFIGMHGFGASGPAPELYQHFGITAEAAVEAVEARLPD

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=658, Percent_Identity=25.6838905775076, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI4507521, Length=658, Percent_Identity=25.6838905775076, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI133778974, Length=576, Percent_Identity=27.0833333333333, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI225637459, Length=271, Percent_Identity=28.4132841328413, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI225637461, Length=243, Percent_Identity=27.9835390946502, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI225637463, Length=240, Percent_Identity=27.9166666666667, Blast_Score=76, Evalue=9e-14,
Organism=Escherichia coli, GI48994911, Length=663, Percent_Identity=50.3770739064857, Blast_Score=642, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=653, Percent_Identity=48.698315467075, Blast_Score=612, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI17539652, Length=580, Percent_Identity=28.1034482758621, Blast_Score=182, Evalue=7e-46,
Organism=Saccharomyces cerevisiae, GI6325331, Length=665, Percent_Identity=45.2631578947368, Blast_Score=523, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6319593, Length=672, Percent_Identity=42.2619047619048, Blast_Score=501, Evalue=1e-142,
Organism=Drosophila melanogaster, GI45551847, Length=675, Percent_Identity=28, Blast_Score=179, Evalue=8e-45,
Organism=Drosophila melanogaster, GI45550715, Length=675, Percent_Identity=28, Blast_Score=179, Evalue=8e-45,
Organism=Drosophila melanogaster, GI24666278, Length=571, Percent_Identity=27.1453590192644, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24645119, Length=644, Percent_Identity=27.639751552795, Blast_Score=159, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74737; Mature: 74737

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRLLLRARAPPVPDRPQPTQRAHMISREKHDRMANAIRFLSMDAVEKAKSGHPGLPMGT
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ADIATVLFTRFMKHDPKTPHWPDRDRFVLSAGHGSMLLYSLLHLLGYEDITIEEIKNFRQ
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
LGSRTAGHPEYGFAAGIETTTGPLGQGFGNAVGMAIAERLLNARYGDDLVNHFTYALVGD
HHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GCLMEGISQEALTLAGHLRLNKLIVLFDDNHISIDGPVSLADSTDQCARFAASGWNTLRA
CHHHHCCCHHHHHHHHHEEEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHCCCCEECC
DGHDPDAIASAIETARQSDRPTLIAFRTTIGYGSPSKAGTNKVHGSPLGADEIAKTRSAL
CCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GWDSPPFVVPSEVLDDWRLAGLRSAKERGSWEKRLAAADTETRAQFERRMRGDLPAAFPG
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCH
VIVDYKKKLAQQNTAVATRNASEMALEVINDCIPETVGGSADLTGSNNTKTSQTTPITPT
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
DFSGRYIHFGIREHAMAAAMNGIALHGGLIPYGGTFLTFSDYARPAMRLASLMHIRSIFV
CCCCCEEEECHHHHHHHHHHCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHE
MTHDSIGLGEDGPTHQPVEHLAALRAIPNHNVFRPADATETAECWQLALESRKTPSTIAL
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
TRQKLQPVRLEFEEENLCARGAYELLPASDEAKVTIFASGSEVEIAVKARVMLEERGYPT
HHHHCCCEEEEECCCCHHHCCCHHHCCCCCCCEEEEEECCCEEEEEEEEEEHHHCCCCCE
RVVSVPCFELFEEQSQDYQRAILGDAPVRIAIEAGVRQGWDRFIGVDGIFIGMHGFGASG
EEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCEEEEEEECCCCCC
PAPELYQHFGITAEAAVEAVEARLPD
CCHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MCRLLLRARAPPVPDRPQPTQRAHMISREKHDRMANAIRFLSMDAVEKAKSGHPGLPMGT
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ADIATVLFTRFMKHDPKTPHWPDRDRFVLSAGHGSMLLYSLLHLLGYEDITIEEIKNFRQ
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
LGSRTAGHPEYGFAAGIETTTGPLGQGFGNAVGMAIAERLLNARYGDDLVNHFTYALVGD
HHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GCLMEGISQEALTLAGHLRLNKLIVLFDDNHISIDGPVSLADSTDQCARFAASGWNTLRA
CHHHHCCCHHHHHHHHHEEEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHCCCCEECC
DGHDPDAIASAIETARQSDRPTLIAFRTTIGYGSPSKAGTNKVHGSPLGADEIAKTRSAL
CCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GWDSPPFVVPSEVLDDWRLAGLRSAKERGSWEKRLAAADTETRAQFERRMRGDLPAAFPG
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCH
VIVDYKKKLAQQNTAVATRNASEMALEVINDCIPETVGGSADLTGSNNTKTSQTTPITPT
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
DFSGRYIHFGIREHAMAAAMNGIALHGGLIPYGGTFLTFSDYARPAMRLASLMHIRSIFV
CCCCCEEEECHHHHHHHHHHCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHE
MTHDSIGLGEDGPTHQPVEHLAALRAIPNHNVFRPADATETAECWQLALESRKTPSTIAL
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
TRQKLQPVRLEFEEENLCARGAYELLPASDEAKVTIFASGSEVEIAVKARVMLEERGYPT
HHHHCCCEEEEECCCCHHHCCCHHHCCCCCCCEEEEEECCCEEEEEEEEEEHHHCCCCCE
RVVSVPCFELFEEQSQDYQRAILGDAPVRIAIEAGVRQGWDRFIGVDGIFIGMHGFGASG
EEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCEEEEEEECCCCCC
PAPELYQHFGITAEAAVEAVEARLPD
CCHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]