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The map label for this gene is gap [H]

Identifier: 110635767

GI number: 110635767

Start: 3718473

End: 3719486

Strand: Reverse

Name: gap [H]

Synonym: Meso_3439

Alternate gene names: 110635767

Gene position: 3719486-3718473 (Counterclockwise)

Preceding gene: 110635768

Following gene: 110635766

Centisome position: 84.3

GC content: 59.66

Gene sequence:

>1014_bases
ATGACTGTCAAAGTAGCCGTAAACGGATTTGGCCGCATCGGCCGCAACATCGTACGCGCCATCTATGAGTCGGGCCGCAA
GGATATCGACGTTGTGGCCGTCAACGACCTCGGGCCCGTTGAGAGCAACGCCCATCTGTTGCGCTATGACAGCGTGCATG
GCCGCTTTCCCGGCGAAGTGAAGGTCGAGGGCGATAGCATCAGCATCGGCGCCGACTCCTTCAAGGTGCTCGCAGAACGC
GATCCCTCCAAGCTGCCGTGGAAGGATCTCGGCGTGGACATCGTGCTCGAGTGCACGGGCCTCTTCACGTCCAAGGACAA
AGCTTCTGCGCATCTTGCCGCTGGTGCCAAGCGTGTGCTCGTCTCCGCACCGGCGGATGGCGCCGACATTACGGTGGTCT
ATGGCGTGAACCACGACAAGATTACCAAGGACCATGTCGTCCTTTCCAACGCCTCCTGCACCACCAACTGCCTGGCGCCG
GTGGCCAAGGTGCTGAATGACGCCTTCGGCATCGAGAAGGGCTTCATGACCACCGTGCATTCCTATACGGGCGATCAGCC
GACGCTGGACACGATGCACAAGGATCTTTACCGCGCCCGCGCGGCAGCCCTGTCGATGATCCCAACATCAACCGGTGCTG
CAAAAGCTGTCGGTCTCGTCCTGCCAGAACTCAATGGAAAACTCGACGGCGTATCGATCCGCGTTCCCACGCCGAATGTC
TCGGTCATCGATTTCAAATTTGTGCCGAAGCGCAAAGTCACGGTTCAGGAGGTGAATGAGGCCCTCGTTGCCGCGGCCAC
CGAGGGTCCGCTGAAAGGCGTCCTTGCCTACACGAAGGAGCCGCTGGTCTCGTCCGATTTCAACCACGATCCAGCCTCCT
CCACCTTCGCGCTCGACCAAACCAAGGTAATCGATGGCGATCTGGTGCGGGTCATGTCCTGGTATGACAACGAGTGGGGC
TTCTCAAATCGCATGGCCGATGTCACGGCGGTCATCGCAAATACGCTCCGCTGA

Upstream 100 bases:

>100_bases
TTGCGCCGGGAGGCGCAGTCGGTTTTTTAGCGGACGCCGCCGCGAAATCGGCGTCCAGCTATGCTTCCATGTATCGTGTC
ACGCTCGCCGGAGGTAGTTC

Downstream 100 bases:

>100_bases
TAAACGGAACTGTTTTTTGTTAGAGGCCCGGCTCTCCGCCGGGCCTTTTTATTTCTGCAACAGCTTGCGCAATCATATAG
TTTTACCGCACTTTAGCCGC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTVKVAVNGFGRIGRNIVRAIYESGRKDIDVVAVNDLGPVESNAHLLRYDSVHGRFPGEVKVEGDSISIGADSFKVLAER
DPSKLPWKDLGVDIVLECTGLFTSKDKASAHLAAGAKRVLVSAPADGADITVVYGVNHDKITKDHVVLSNASCTTNCLAP
VAKVLNDAFGIEKGFMTTVHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELNGKLDGVSIRVPTPNV
SVIDFKFVPKRKVTVQEVNEALVAAATEGPLKGVLAYTKEPLVSSDFNHDPASSTFALDQTKVIDGDLVRVMSWYDNEWG
FSNRMADVTAVIANTLR

Sequences:

>Translated_337_residues
MTVKVAVNGFGRIGRNIVRAIYESGRKDIDVVAVNDLGPVESNAHLLRYDSVHGRFPGEVKVEGDSISIGADSFKVLAER
DPSKLPWKDLGVDIVLECTGLFTSKDKASAHLAAGAKRVLVSAPADGADITVVYGVNHDKITKDHVVLSNASCTTNCLAP
VAKVLNDAFGIEKGFMTTVHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELNGKLDGVSIRVPTPNV
SVIDFKFVPKRKVTVQEVNEALVAAATEGPLKGVLAYTKEPLVSSDFNHDPASSTFALDQTKVIDGDLVRVMSWYDNEWG
FSNRMADVTAVIANTLR
>Mature_336_residues
TVKVAVNGFGRIGRNIVRAIYESGRKDIDVVAVNDLGPVESNAHLLRYDSVHGRFPGEVKVEGDSISIGADSFKVLAERD
PSKLPWKDLGVDIVLECTGLFTSKDKASAHLAAGAKRVLVSAPADGADITVVYGVNHDKITKDHVVLSNASCTTNCLAPV
AKVLNDAFGIEKGFMTTVHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELNGKLDGVSIRVPTPNVS
VIDFKFVPKRKVTVQEVNEALVAAATEGPLKGVLAYTKEPLVSSDFNHDPASSTFALDQTKVIDGDLVRVMSWYDNEWGF
SNRMADVTAVIANTLR

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=49.4011976047904, Blast_Score=319, Evalue=2e-87,
Organism=Homo sapiens, GI7657116, Length=328, Percent_Identity=44.5121951219512, Blast_Score=273, Evalue=2e-73,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=50.4477611940299, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=49.1017964071856, Blast_Score=320, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=48.8165680473373, Blast_Score=308, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=48.5207100591716, Blast_Score=308, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=48.2248520710059, Blast_Score=301, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=48.2248520710059, Blast_Score=301, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=49.4047619047619, Blast_Score=313, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=49.2537313432836, Blast_Score=309, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=48.6567164179104, Blast_Score=302, Evalue=6e-83,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=48.9296636085627, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=48.9296636085627, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=48.6238532110092, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=48.6238532110092, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=43.1192660550459, Blast_Score=271, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36090; Mature: 35959

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKVAVNGFGRIGRNIVRAIYESGRKDIDVVAVNDLGPVESNAHLLRYDSVHGRFPGEV
CEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCEE
KVEGDSISIGADSFKVLAERDPSKLPWKDLGVDIVLECTGLFTSKDKASAHLAAGAKRVL
EECCCEEEECCCCCCEEECCCCCCCCHHHCCEEEEEEEECCCCCCCCCHHHHHCCCEEEE
VSAPADGADITVVYGVNHDKITKDHVVLSNASCTTNCLAPVAKVLNDAFGIEKGFMTTVH
EECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELNGKLDGVSIRVPTPNV
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEECCCCCCCCEEEEECCCCC
SVIDFKFVPKRKVTVQEVNEALVAAATEGPLKGVLAYTKEPLVSSDFNHDPASSTFALDQ
EEEEEEECCCCCCHHHHHHHHHEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEECC
TKVIDGDLVRVMSWYDNEWGFSNRMADVTAVIANTLR
EEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVKVAVNGFGRIGRNIVRAIYESGRKDIDVVAVNDLGPVESNAHLLRYDSVHGRFPGEV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCEE
KVEGDSISIGADSFKVLAERDPSKLPWKDLGVDIVLECTGLFTSKDKASAHLAAGAKRVL
EECCCEEEECCCCCCEEECCCCCCCCHHHCCEEEEEEEECCCCCCCCCHHHHHCCCEEEE
VSAPADGADITVVYGVNHDKITKDHVVLSNASCTTNCLAPVAKVLNDAFGIEKGFMTTVH
EECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELNGKLDGVSIRVPTPNV
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEECCCCCCCCEEEEECCCCC
SVIDFKFVPKRKVTVQEVNEALVAAATEGPLKGVLAYTKEPLVSSDFNHDPASSTFALDQ
EEEEEEECCCCCCHHHHHHHHHEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEECC
TKVIDGDLVRVMSWYDNEWGFSNRMADVTAVIANTLR
EEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]