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The map label for this gene is cvrA [H]

Identifier: 110635766

GI number: 110635766

Start: 3716500

End: 3718350

Strand: Reverse

Name: cvrA [H]

Synonym: Meso_3438

Alternate gene names: 110635766

Gene position: 3718350-3716500 (Counterclockwise)

Preceding gene: 110635767

Following gene: 110635765

Centisome position: 84.27

GC content: 60.4

Gene sequence:

>1851_bases
ATGGATCCGACCATCTATTTGATAACACTCGTTGGCACCGCGCTTGTCCTCATCGCGGCCTTTTCAAGCCTAATAGCGTT
TCGCTTTGGCGCACCCCTCCTTCTCATCTTTCTTGGAATCGGATTGGCGGCCGGAACGGACGGCTTTGGCGGCATCGATT
TCGACAACGCTCCTATCGCCTTCTTTATTGGCTCCCTTGCTCTTGCGGTGATCCTATTCGATTCCGGTTTCGGCACGAGC
TTTGCCAGTTTCCGTTCGGCATCCGCGCCAGCCATCGTCTTGGCCACGGTCGGCGTCATCGCAACCACGGGCCTTATTGC
GGTCGCCAGCCACTATGTGGCGGGATTCGCTTGGCTTGAGTCGTTCCTGCTGGGCGCGGCAGTGGCCTCTACGGACGCGG
CTGCGGTGTTCTTCCTCTTGCGTGTCGGTAATATATCAGTGCGAGACCGGGTCCGCTCGACCCTTGAGGTGGAGTCGGGC
TCCAACGACCCGATGGCCATCTTCCTTACGCTTTCGCTCGTGAGCCTCGTCGCTTCCGGTGAGGTTCTCGAGCCGGGCGC
ACTCGCTGGAGAAATCGTTCTGGGATTTCTCCAGCAGATGGTTATCGGCCTCGTTGTCGGTCTGCTCGGCGGATATCTCA
TTGTGCGCCTGGTTCTGCGGCTTCGCCTGGAACAGGGGCTCCTCCCTATCTTCGTCCTGGCGCTGTCCCTCCTTGTCTTT
GCGCTTACGGGAGCCATAGGCGGTTCCGGGTTTCTTGCGGTCTATGTGGCCGGTATGGTCGCCGGCAATGCTCGCATGCG
CTCCACAGGGATGCTGAAGCGCTTCCAGGATGGCGTGACATGGCTGGCGCAGATCATCATGTTCCTGGTGCTCGGCCTTT
TTGCAACGCCATCCCAGTTCGCCGATATTCTGTTGCCAGCTCTTTTCATTGGCTTGTTCCTTATCTTCGTCGCCCGTCCA
GTTGCGGTGGCGCTCTGCCTTGCGCCCTTTCGTTTCACCAAAGCGGAGACGGCCTTCATTTCCTGGGTAGGTCTGCGCGG
AGCTGTTTCCATCCTGCTTGCACTCCTGCCGATCTTGCAGGAGGTCGAGAACGGGCGGGCCATCTTCAACATCGTCTTTA
TAGTGGTGCTTGTGTCGCTGGTCCTGCAGGGCTGGAGCATCGGCCCGGTTGCGCGCCGGCTCGGCATGATCCTGCCACCG
CGCATCGGCCCTGTGGACAAGGTGGAATTGGAACTGCCGGGTTCGGCCCATCATGAGCTCCTCGCCTACCGCGTCGTGGC
GGGAAGTCCTGTCGAGCGCGGCGAGCGCATTCCGCGCTGGGCACGCCCGTCTCTCGTGGTGCGCGACGGCCGTTCGATGG
CGTATCAATATGCAGGCCGGCTGATGGCCGGCGACCGCGTGTATATTTTTGTGCCGGACCGCTATCCGCGACTTCTCGAT
CGCCTCTTCGCAAGCCCCACCGATGTCGATCCAGAGGACGCCGATTTCTTCGGCGCTTTCGCGGTGGATCCGAAAAGGCC
GATGGCCGATATCGAGGCAGCTTATGCATTGGGGCTGAGTGAGGAAGACCAAGCGCTTCTTATCAGCGATTTCGTGCGCA
TGCGCTTGGGCGGGCGCGCGGAATATGGTGACCGGGTGCCGCTCGGTAGTGTGGAACTCATCGTGCGCGACGTTGATGAA
AATGGCCATATCACCTCCATCGGCCTCTCCGTCGATCCGCCGCTGCGGCCGCCTCAGGTGCCGGTTTTCATTAGTGCCGG
TGAGGCGCTGAGCCGCCTTTGGGGCTTTTTTCAGCGCCGCCGAAAACCGGGTCGTTCGGCCACGAAAGCAGAGGAAGGCA
TTCAGGAGTAA

Upstream 100 bases:

>100_bases
GAGGCCCGGCTCTCCGCCGGGCCTTTTTATTTCTGCAACAGCTTGCGCAATCATATAGTTTTACCGCACTTTAGCCGCAT
GACACGTCTTAGAGAGGTCT

Downstream 100 bases:

>100_bases
ATCCCGCCTTGCGTGATGCCGGGCGGGCTGTATTTTCCCGCGCGTTGCCAGTTCGAGGAGAGCAAGTCATGGCCGGTTTC
AAGACATTGGACGATTTGAA

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MDPTIYLITLVGTALVLIAAFSSLIAFRFGAPLLLIFLGIGLAAGTDGFGGIDFDNAPIAFFIGSLALAVILFDSGFGTS
FASFRSASAPAIVLATVGVIATTGLIAVASHYVAGFAWLESFLLGAAVASTDAAAVFFLLRVGNISVRDRVRSTLEVESG
SNDPMAIFLTLSLVSLVASGEVLEPGALAGEIVLGFLQQMVIGLVVGLLGGYLIVRLVLRLRLEQGLLPIFVLALSLLVF
ALTGAIGGSGFLAVYVAGMVAGNARMRSTGMLKRFQDGVTWLAQIIMFLVLGLFATPSQFADILLPALFIGLFLIFVARP
VAVALCLAPFRFTKAETAFISWVGLRGAVSILLALLPILQEVENGRAIFNIVFIVVLVSLVLQGWSIGPVARRLGMILPP
RIGPVDKVELELPGSAHHELLAYRVVAGSPVERGERIPRWARPSLVVRDGRSMAYQYAGRLMAGDRVYIFVPDRYPRLLD
RLFASPTDVDPEDADFFGAFAVDPKRPMADIEAAYALGLSEEDQALLISDFVRMRLGGRAEYGDRVPLGSVELIVRDVDE
NGHITSIGLSVDPPLRPPQVPVFISAGEALSRLWGFFQRRRKPGRSATKAEEGIQE

Sequences:

>Translated_616_residues
MDPTIYLITLVGTALVLIAAFSSLIAFRFGAPLLLIFLGIGLAAGTDGFGGIDFDNAPIAFFIGSLALAVILFDSGFGTS
FASFRSASAPAIVLATVGVIATTGLIAVASHYVAGFAWLESFLLGAAVASTDAAAVFFLLRVGNISVRDRVRSTLEVESG
SNDPMAIFLTLSLVSLVASGEVLEPGALAGEIVLGFLQQMVIGLVVGLLGGYLIVRLVLRLRLEQGLLPIFVLALSLLVF
ALTGAIGGSGFLAVYVAGMVAGNARMRSTGMLKRFQDGVTWLAQIIMFLVLGLFATPSQFADILLPALFIGLFLIFVARP
VAVALCLAPFRFTKAETAFISWVGLRGAVSILLALLPILQEVENGRAIFNIVFIVVLVSLVLQGWSIGPVARRLGMILPP
RIGPVDKVELELPGSAHHELLAYRVVAGSPVERGERIPRWARPSLVVRDGRSMAYQYAGRLMAGDRVYIFVPDRYPRLLD
RLFASPTDVDPEDADFFGAFAVDPKRPMADIEAAYALGLSEEDQALLISDFVRMRLGGRAEYGDRVPLGSVELIVRDVDE
NGHITSIGLSVDPPLRPPQVPVFISAGEALSRLWGFFQRRRKPGRSATKAEEGIQE
>Mature_616_residues
MDPTIYLITLVGTALVLIAAFSSLIAFRFGAPLLLIFLGIGLAAGTDGFGGIDFDNAPIAFFIGSLALAVILFDSGFGTS
FASFRSASAPAIVLATVGVIATTGLIAVASHYVAGFAWLESFLLGAAVASTDAAAVFFLLRVGNISVRDRVRSTLEVESG
SNDPMAIFLTLSLVSLVASGEVLEPGALAGEIVLGFLQQMVIGLVVGLLGGYLIVRLVLRLRLEQGLLPIFVLALSLLVF
ALTGAIGGSGFLAVYVAGMVAGNARMRSTGMLKRFQDGVTWLAQIIMFLVLGLFATPSQFADILLPALFIGLFLIFVARP
VAVALCLAPFRFTKAETAFISWVGLRGAVSILLALLPILQEVENGRAIFNIVFIVVLVSLVLQGWSIGPVARRLGMILPP
RIGPVDKVELELPGSAHHELLAYRVVAGSPVERGERIPRWARPSLVVRDGRSMAYQYAGRLMAGDRVYIFVPDRYPRLLD
RLFASPTDVDPEDADFFGAFAVDPKRPMADIEAAYALGLSEEDQALLISDFVRMRLGGRAEYGDRVPLGSVELIVRDVDE
NGHITSIGLSVDPPLRPPQVPVFISAGEALSRLWGFFQRRRKPGRSATKAEEGIQE

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=576, Percent_Identity=40.1041666666667, Blast_Score=325, Evalue=6e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 65915; Mature: 65915

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPTIYLITLVGTALVLIAAFSSLIAFRFGAPLLLIFLGIGLAAGTDGFGGIDFDNAPIA
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
FFIGSLALAVILFDSGFGTSFASFRSASAPAIVLATVGVIATTGLIAVASHYVAGFAWLE
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFLLGAAVASTDAAAVFFLLRVGNISVRDRVRSTLEVESGSNDPMAIFLTLSLVSLVASG
HHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCEEHHHHHHHHHHHHCC
EVLEPGALAGEIVLGFLQQMVIGLVVGLLGGYLIVRLVLRLRLEQGLLPIFVLALSLLVF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ALTGAIGGSGFLAVYVAGMVAGNARMRSTGMLKRFQDGVTWLAQIIMFLVLGLFATPSQF
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ADILLPALFIGLFLIFVARPVAVALCLAPFRFTKAETAFISWVGLRGAVSILLALLPILQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVENGRAIFNIVFIVVLVSLVLQGWSIGPVARRLGMILPPRIGPVDKVELELPGSAHHEL
HHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHH
LAYRVVAGSPVERGERIPRWARPSLVVRDGRSMAYQYAGRLMAGDRVYIFVPDRYPRLLD
HHHHHHCCCCHHHHCCCCCCCCCCEEEECCHHHHHHHHCCEEECCEEEEEECCCCHHHHH
RLFASPTDVDPEDADFFGAFAVDPKRPMADIEAAYALGLSEEDQALLISDFVRMRLGGRA
HHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
EYGDRVPLGSVELIVRDVDENGHITSIGLSVDPPLRPPQVPVFISAGEALSRLWGFFQRR
CCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
RKPGRSATKAEEGIQE
CCCCCCCHHHHCCCCC
>Mature Secondary Structure
MDPTIYLITLVGTALVLIAAFSSLIAFRFGAPLLLIFLGIGLAAGTDGFGGIDFDNAPIA
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
FFIGSLALAVILFDSGFGTSFASFRSASAPAIVLATVGVIATTGLIAVASHYVAGFAWLE
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFLLGAAVASTDAAAVFFLLRVGNISVRDRVRSTLEVESGSNDPMAIFLTLSLVSLVASG
HHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCEEHHHHHHHHHHHHCC
EVLEPGALAGEIVLGFLQQMVIGLVVGLLGGYLIVRLVLRLRLEQGLLPIFVLALSLLVF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ALTGAIGGSGFLAVYVAGMVAGNARMRSTGMLKRFQDGVTWLAQIIMFLVLGLFATPSQF
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ADILLPALFIGLFLIFVARPVAVALCLAPFRFTKAETAFISWVGLRGAVSILLALLPILQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVENGRAIFNIVFIVVLVSLVLQGWSIGPVARRLGMILPPRIGPVDKVELELPGSAHHEL
HHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHH
LAYRVVAGSPVERGERIPRWARPSLVVRDGRSMAYQYAGRLMAGDRVYIFVPDRYPRLLD
HHHHHHCCCCHHHHCCCCCCCCCCEEEECCHHHHHHHHCCEEECCEEEEEECCCCHHHHH
RLFASPTDVDPEDADFFGAFAVDPKRPMADIEAAYALGLSEEDQALLISDFVRMRLGGRA
HHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
EYGDRVPLGSVELIVRDVDENGHITSIGLSVDPPLRPPQVPVFISAGEALSRLWGFFQRR
CCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
RKPGRSATKAEEGIQE
CCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]