BacMap

Definition	Mesorhizobium sp. BNC1, complete genome.
Accession	NC_008254
Length	4,412,446

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The map label for this gene is gdh [H]

Identifier: 110635762

GI number: 110635762

Start: 3712884

End: 3713675

Strand: Reverse

Name: gdh [H]

Synonym: Meso_3434

Alternate gene names: 110635762

Gene position: 3713675-3712884 (Counterclockwise)

Preceding gene: 110635764

Following gene: 110635761

Centisome position: 84.16

GC content: 56.94

Gene sequence:

>792_bases
ATGGCTCTGGACGGGAAAACGGCGGTTGTCACAGGCGGGGCCGGCGGGATCGGCTATGCCGTTGCGGAGCGGTTTTTGCG
AGAAGGCATGCGCGTCGTAATCGCCGATATTGACGGAGAAAAGGGCACCCGTTCACTGAAGAGCCTTGAGAAACTGGGCG
AAGCCTGGTTTGCCAAGGCGGACGTCGGGAGGAGCCTGGATGTCCATAATCTGATTGCTTTCACCATTGATGCGCTGGGG
GACATTGATGTCCTTGTGAATAATGCCGGGATCGCTCACGGCGCAGACTTCCTCGATCTGAGGGAGGAGGATTTCGATCG
CGTTTTGCGCGTGAACCTCAAGGGCGCTTTTCTCGTCGGACAGGCTGCGGCCCGATTTATGGTCGAGAAGGTGCAAAATG
GCGGGCCGGCCGGGGCAATCATCAACATGTCCTCCGTCAACGCGGTTTTCGCAATCGCCGATCAGGTGCCCTATTCGATC
TCGAAGGGCGGCGTGAACCAGCTCACCAAGGTGATGGCGCTCGCGCTTGCGCCACATGGCATACGGGTCAATGCGATCGG
ACCCGGCTCCATCATGACCGACATGCTTACGAGCGTTAATGATGATCCAGATGCTCGGGAACGCATTCTCTCGAGAACTC
CGCTTGGCCGCATTGGTGATCCTCAAGAGATCGCATCTATTGCAGCATTCCTGGCCTCTGACGAAGCAAGCTATATTACT
GGCCAGACAATTTATGCCGATGGTGGACGCTTGCCGCTAAACTACACCGTCTCCGTTCGGTCCGAGGATTAA

Upstream 100 bases:

>100_bases
ATGTTGCCGCGGACGTGAGAGCGCCGTTGCCCTAAAGGAATGCTTGACCGGGCGTCGCGGCAAGACCAGTTTTCTCGGGG
CAAGGCTAAGGAGTGGTGCC

Downstream 100 bases:

>100_bases
GCCTTCGCCGCCAAAGCCTCCTGACGAAACGCTGTCATTACGGACCTGAGATAATCCTCCGCGATGAATGATGGAGGTAG
AGCTATGGTTGTTGCGAGAA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MALDGKTAVVTGGAGGIGYAVAERFLREGMRVVIADIDGEKGTRSLKSLEKLGEAWFAKADVGRSLDVHNLIAFTIDALG
DIDVLVNNAGIAHGADFLDLREEDFDRVLRVNLKGAFLVGQAAARFMVEKVQNGGPAGAIINMSSVNAVFAIADQVPYSI
SKGGVNQLTKVMALALAPHGIRVNAIGPGSIMTDMLTSVNDDPDARERILSRTPLGRIGDPQEIASIAAFLASDEASYIT
GQTIYADGGRLPLNYTVSVRSED

Sequences:

>Translated_263_residues
MALDGKTAVVTGGAGGIGYAVAERFLREGMRVVIADIDGEKGTRSLKSLEKLGEAWFAKADVGRSLDVHNLIAFTIDALG
DIDVLVNNAGIAHGADFLDLREEDFDRVLRVNLKGAFLVGQAAARFMVEKVQNGGPAGAIINMSSVNAVFAIADQVPYSI
SKGGVNQLTKVMALALAPHGIRVNAIGPGSIMTDMLTSVNDDPDARERILSRTPLGRIGDPQEIASIAAFLASDEASYIT
GQTIYADGGRLPLNYTVSVRSED
>Mature_262_residues
ALDGKTAVVTGGAGGIGYAVAERFLREGMRVVIADIDGEKGTRSLKSLEKLGEAWFAKADVGRSLDVHNLIAFTIDALGD
IDVLVNNAGIAHGADFLDLREEDFDRVLRVNLKGAFLVGQAAARFMVEKVQNGGPAGAIINMSSVNAVFAIADQVPYSIS
KGGVNQLTKVMALALAPHGIRVNAIGPGSIMTDMLTSVNDDPDARERILSRTPLGRIGDPQEIASIAAFLASDEASYITG
QTIYADGGRLPLNYTVSVRSED

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=34.0080971659919, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=36.5079365079365, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.9317269076305, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=38.6266094420601, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI4758504, Length=257, Percent_Identity=39.2996108949416, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI19923817, Length=273, Percent_Identity=32.2344322344322, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=32.4, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=33.6032388663968, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI83715985, Length=257, Percent_Identity=36.9649805447471, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI31542939, Length=214, Percent_Identity=33.6448598130841, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=30.952380952381, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI10190704, Length=259, Percent_Identity=32.046332046332, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=33.502538071066, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=32.9545454545455, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4504505, Length=207, Percent_Identity=31.4009661835749, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=30.1075268817204, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503301, Length=183, Percent_Identity=30.0546448087432, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4503817, Length=231, Percent_Identity=25.1082251082251, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=35.3174603174603, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=36, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082100, Length=272, Percent_Identity=36.3970588235294, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=35.2, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=35.5731225296443, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=32.5396825396825, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=35.8565737051793, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=36.8, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=32.4324324324324, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=30.4347826086957, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=33.8461538461538, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=30.241935483871, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787545, Length=253, Percent_Identity=25.296442687747, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=28.1081081081081, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=37.9032258064516, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=36.4372469635627, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=34.9397590361446, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=34.0909090909091, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=35.0393700787402, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=30.6201550387597, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=31.8181818181818, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=30.1526717557252, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=29.296875, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=31.4393939393939, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=33.587786259542, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=31.6981132075472, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=31.9672131147541, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=30.6818181818182, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=32.0610687022901, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=30.9160305343511, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=33.457249070632, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=33.206106870229, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=30.6818181818182, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=32.0754716981132, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=33.0827067669173, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=28.0898876404494, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=31.4393939393939, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=31.640625, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=31.5384615384615, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17536651, Length=270, Percent_Identity=31.8518518518519, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=280, Percent_Identity=30, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=276, Percent_Identity=30.4347826086957, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=276, Percent_Identity=30.0724637681159, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=211, Percent_Identity=30.8056872037915, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=30.7086614173228, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=214, Percent_Identity=28.9719626168224, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI212645366, Length=104, Percent_Identity=37.5, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193207185, Length=150, Percent_Identity=30.6666666666667, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=256, Percent_Identity=26.953125, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=252, Percent_Identity=27.3809523809524, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=29.1828793774319, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6322861, Length=245, Percent_Identity=27.7551020408163, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=247, Percent_Identity=26.7206477732794, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=35.5212355212355, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=37.2549019607843, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=33.59375, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=34.5381526104418, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=35.0597609561753, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=33.4661354581673, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=32.6771653543307, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24643142, Length=259, Percent_Identity=30.5019305019305, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17737361, Length=250, Percent_Identity=33.2, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24665243, Length=224, Percent_Identity=32.5892857142857, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI221331218, Length=221, Percent_Identity=32.1266968325792, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221331216, Length=222, Percent_Identity=31.981981981982, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24665247, Length=225, Percent_Identity=32.4444444444444, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18859837, Length=254, Percent_Identity=31.8897637795276, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281364892, Length=172, Percent_Identity=31.9767441860465, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584744, Length=196, Percent_Identity=29.5918367346939, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574402, Length=196, Percent_Identity=29.5918367346939, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641232, Length=215, Percent_Identity=31.1627906976744, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571387, Length=223, Percent_Identity=26.9058295964126, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=26.7676767676768, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI78706930, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI78706928, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI78706926, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI78706924, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI78706922, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 27730; Mature: 27599

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDGKTAVVTGGAGGIGYAVAERFLREGMRVVIADIDGEKGTRSLKSLEKLGEAWFAKA
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
DVGRSLDVHNLIAFTIDALGDIDVLVNNAGIAHGADFLDLREEDFDRVLRVNLKGAFLVG
CCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEEECCCCEEEHH
QAAARFMVEKVQNGGPAGAIINMSSVNAVFAIADQVPYSISKGGVNQLTKVMALALAPHG
HHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCC
IRVNAIGPGSIMTDMLTSVNDDPDARERILSRTPLGRIGDPQEIASIAAFLASDEASYIT
EEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
GQTIYADGGRLPLNYTVSVRSED
CCEEEECCCCCCEEEEEEEECCC
>Mature Secondary Structure 
ALDGKTAVVTGGAGGIGYAVAERFLREGMRVVIADIDGEKGTRSLKSLEKLGEAWFAKA
CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
DVGRSLDVHNLIAFTIDALGDIDVLVNNAGIAHGADFLDLREEDFDRVLRVNLKGAFLVG
CCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEEECCCCEEEHH
QAAARFMVEKVQNGGPAGAIINMSSVNAVFAIADQVPYSISKGGVNQLTKVMALALAPHG
HHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCC
IRVNAIGPGSIMTDMLTSVNDDPDARERILSRTPLGRIGDPQEIASIAAFLASDEASYIT
EEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
GQTIYADGGRLPLNYTVSVRSED
CCEEEECCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3082854; 8969502; 9384377 [H]