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The map label for this gene is 110635764

Identifier: 110635764

GI number: 110635764

Start: 3714095

End: 3715120

Strand: Reverse

Name: 110635764

Synonym: Meso_3436

Alternate gene names: NA

Gene position: 3715120-3714095 (Counterclockwise)

Preceding gene: 110635765

Following gene: 110635762

Centisome position: 84.2

GC content: 62.38

Gene sequence:

>1026_bases
ATGAGCGAGAGGCTGGAAGATATAGCGGCCCGGATGGTGGCCGACGGCAAAGGGATTCTCGCGGCGGACGAAAGCAGCGG
CACGATCAAGAAGCGCTTCGACTCGATCGGCCTCGAATCGACCGCAGACAACCGCCGCGACTATCGCGAGATGTTGTTTC
GCGCCGACGAGGCCATGCGGAACTCCATTTCGGGCGTTATTCTCTACGATGAGACCCTGCGCCAGCAGGCGAAGGACGGA
ACGCCCCTCGTGGAGATCATCAGCCGTTCCGGCGCGGTGCCGGGGATTAAAGTGGATGCAGGCGCCAAGCCGCTGGCAGG
CTTCCCGGGCGAGACCATTACGGAGGGCCTCGATGGTCTGCGCGAGCGCCTGAAGGAATATTACGAACTTGGCGCACGCT
TCGCAAAGTGGCGCGGCGTGATCGCTGTTTCCGACGATCTTCCGACCTGGGGTTCGGTGAAGCAGAACGCGCAAGCGCTG
GCTCGCTACGCCGCCCTTTGCCAGGAAGCCGGGATTGTACCGATCGTGGAGCCGGAAGTGCTGATGGACGGCACGCCCGC
AACCCACTCCATCGATCGGTGCTACGAGGTTACCGAGTGGGTGCTGAAGACGGTCTTCACCGAGCTGTTCGATGCCCGTG
TCGCGCTCGAAGGCATGGTGTTGAAGCCGAATATGGTTATTGACGGCAAGAACGCGCGCAAGGCGTCACGGGAGGAGGTG
GCTGAAAAGACCGTTCGCTGCCTCAAGGCGACCGTTCCTGCGGCGGTGCCGGGTATCGCCTTCCTCTCAGGCGGCCAGTC
CGACGAAGAGGCGACGGCGCATCTCTCTCTCATGAATGCATCCCACTCGATGCCATGGAAGCTGACCTTCTCTTACGGGC
GTGCTCTGCAGGCCGCGGCACTCAAGGCTTGGGGCGGCAAAAGCGAGAATGTCGCTGCTGGCCAGCGCGCCTTTGCGCAC
CGCGCGCGTATGAATGCTCTCGCCGCTCGAGGTGACTGGAAGCAAGAGCTGGAAGTGGCTGCTTAA

Upstream 100 bases:

>100_bases
GAAATAATTCTTTACATTTCAATCGATTAGGGAGCTTTGTCCGGCATTCCGTTTTTTTGAGCCATCTGATATTCGGCATG
TGTTCACACAGGAGGCAAGA

Downstream 100 bases:

>100_bases
AGGTCGCGGCAGGCGGCTGGGCAGCCGGCCGCCTGCCTAGCCACGGAGATGGCTCAAGCCAACCGTTGCCGCCATCGCAG
CGAGCGCGATTATCGCGAGT

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSERLEDIAARMVADGKGILAADESSGTIKKRFDSIGLESTADNRRDYREMLFRADEAMRNSISGVILYDETLRQQAKDG
TPLVEIISRSGAVPGIKVDAGAKPLAGFPGETITEGLDGLRERLKEYYELGARFAKWRGVIAVSDDLPTWGSVKQNAQAL
ARYAALCQEAGIVPIVEPEVLMDGTPATHSIDRCYEVTEWVLKTVFTELFDARVALEGMVLKPNMVIDGKNARKASREEV
AEKTVRCLKATVPAAVPGIAFLSGGQSDEEATAHLSLMNASHSMPWKLTFSYGRALQAAALKAWGGKSENVAAGQRAFAH
RARMNALAARGDWKQELEVAA

Sequences:

>Translated_341_residues
MSERLEDIAARMVADGKGILAADESSGTIKKRFDSIGLESTADNRRDYREMLFRADEAMRNSISGVILYDETLRQQAKDG
TPLVEIISRSGAVPGIKVDAGAKPLAGFPGETITEGLDGLRERLKEYYELGARFAKWRGVIAVSDDLPTWGSVKQNAQAL
ARYAALCQEAGIVPIVEPEVLMDGTPATHSIDRCYEVTEWVLKTVFTELFDARVALEGMVLKPNMVIDGKNARKASREEV
AEKTVRCLKATVPAAVPGIAFLSGGQSDEEATAHLSLMNASHSMPWKLTFSYGRALQAAALKAWGGKSENVAAGQRAFAH
RARMNALAARGDWKQELEVAA
>Mature_340_residues
SERLEDIAARMVADGKGILAADESSGTIKKRFDSIGLESTADNRRDYREMLFRADEAMRNSISGVILYDETLRQQAKDGT
PLVEIISRSGAVPGIKVDAGAKPLAGFPGETITEGLDGLRERLKEYYELGARFAKWRGVIAVSDDLPTWGSVKQNAQALA
RYAALCQEAGIVPIVEPEVLMDGTPATHSIDRCYEVTEWVLKTVFTELFDARVALEGMVLKPNMVIDGKNARKASREEVA
EKTVRCLKATVPAAVPGIAFLSGGQSDEEATAHLSLMNASHSMPWKLTFSYGRALQAAALKAWGGKSENVAAGQRAFAHR
ARMNALAARGDWKQELEVAA

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=333, Percent_Identity=54.3543543543543, Blast_Score=352, Evalue=4e-97,
Organism=Homo sapiens, GI34577110, Length=333, Percent_Identity=54.3543543543543, Blast_Score=352, Evalue=4e-97,
Organism=Homo sapiens, GI4557305, Length=333, Percent_Identity=54.3543543543543, Blast_Score=352, Evalue=4e-97,
Organism=Homo sapiens, GI193794814, Length=333, Percent_Identity=54.3543543543543, Blast_Score=352, Evalue=4e-97,
Organism=Homo sapiens, GI4885063, Length=334, Percent_Identity=52.6946107784431, Blast_Score=337, Evalue=1e-92,
Organism=Homo sapiens, GI40354205, Length=333, Percent_Identity=51.0510510510511, Blast_Score=326, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI71983985, Length=333, Percent_Identity=51.3513513513513, Blast_Score=328, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI25150450, Length=334, Percent_Identity=49.1017964071856, Blast_Score=325, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI71983990, Length=239, Percent_Identity=48.9539748953975, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24650282, Length=334, Percent_Identity=52.9940119760479, Blast_Score=347, Evalue=7e-96,
Organism=Drosophila melanogaster, GI24650280, Length=334, Percent_Identity=52.9940119760479, Blast_Score=347, Evalue=7e-96,
Organism=Drosophila melanogaster, GI24650278, Length=334, Percent_Identity=52.9940119760479, Blast_Score=347, Evalue=7e-96,
Organism=Drosophila melanogaster, GI221459619, Length=334, Percent_Identity=52.9940119760479, Blast_Score=347, Evalue=9e-96,
Organism=Drosophila melanogaster, GI24650288, Length=334, Percent_Identity=52.9940119760479, Blast_Score=347, Evalue=9e-96,
Organism=Drosophila melanogaster, GI45553577, Length=334, Percent_Identity=52.6946107784431, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI24650304, Length=335, Percent_Identity=43.8805970149254, Blast_Score=289, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37029; Mature: 36897

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLEDIAARMVADGKGILAADESSGTIKKRFDSIGLESTADNRRDYREMLFRADEAMR
CCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NSISGVILYDETLRQQAKDGTPLVEIISRSGAVPGIKVDAGAKPLAGFPGETITEGLDGL
HCCCEEEEECHHHHHHHCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHH
RERLKEYYELGARFAKWRGVIAVSDDLPTWGSVKQNAQALARYAALCQEAGIVPIVEPEV
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCHH
LMDGTPATHSIDRCYEVTEWVLKTVFTELFDARVALEGMVLKPNMVIDGKNARKASREEV
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCHHHHHHHHH
AEKTVRCLKATVPAAVPGIAFLSGGQSDEEATAHLSLMNASHSMPWKLTFSYGRALQAAA
HHHHHHHHHHHCCHHHCCHHEECCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHH
LKAWGGKSENVAAGQRAFAHRARMNALAARGDWKQELEVAA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure 
SERLEDIAARMVADGKGILAADESSGTIKKRFDSIGLESTADNRRDYREMLFRADEAMR
CHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NSISGVILYDETLRQQAKDGTPLVEIISRSGAVPGIKVDAGAKPLAGFPGETITEGLDGL
HCCCEEEEECHHHHHHHCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHH
RERLKEYYELGARFAKWRGVIAVSDDLPTWGSVKQNAQALARYAALCQEAGIVPIVEPEV
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCHH
LMDGTPATHSIDRCYEVTEWVLKTVFTELFDARVALEGMVLKPNMVIDGKNARKASREEV
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCHHHHHHHHH
AEKTVRCLKATVPAAVPGIAFLSGGQSDEEATAHLSLMNASHSMPWKLTFSYGRALQAAA
HHHHHHHHHHHCCHHHCCHHEECCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHH
LKAWGGKSENVAAGQRAFAHRARMNALAARGDWKQELEVAA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]