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The map label for this gene is mtgA

Identifier: 110635756

GI number: 110635756

Start: 3706786

End: 3707517

Strand: Reverse

Name: mtgA

Synonym: Meso_3428

Alternate gene names: 110635756

Gene position: 3707517-3706786 (Counterclockwise)

Preceding gene: 110635758

Following gene: 110635755

Centisome position: 84.02

GC content: 60.79

Gene sequence:

>732_bases
GTGGAAGCGGAAAGGCGGCCTGGTCCAGTCCGGCGGCGCCGGCGGTCGGGGTTGGCGGGGCGCTTTGCGAACCGGCTCGT
CCGCGCGGCGGTTCTTGTCGCTATTGTCCCGCTGGTTCTCACGCTTATTTATTGTCTGCCGTTCGTGCACCCCGTTTCCA
CTTTGATGCTTGCCGATCTTGCGACGCTTCGCGGCTATGAGCGGCAATGGACACCGCTCGAGGAGGCGGGCAGGAACGTC
ATCCATTCTGTAATGATGTCGGAAGACGGGCAGTTTTGCAGCCACCGGGGCATCGATTTGGGCGAACTGAAAGCAGCCAT
CAATGAAGCTCTTTCGGGCGAAAGAACTCGCGGCGCCTCTACAATCCCCATGCAGACGGTGAAAAACCTCTATCTTTGGC
CCGGCCGATCGTTTCTGCGAAAGGCAATCGAGGCTCCCCTTGCCATTTACCTCGACGCCGTTATGCCCAAACACAGGATC
ATGGAAATTTACCTCAACATCGCCGAGTGGGGGCCGGGCATCTATGGAGTGGAGGCGGCAGCGCAACATTATTTCGGCCG
CCCGTCCAGGGATCTGTCAAGGCGTGAGGCAGCTCTTCTTGCCGTAACGCTGCCAAACCCGAGCGAGCGCAATCCCGCCC
AGCCCTCAGCTGCTTTGAGGCGGCTTGCTTCCGTCGTCGAGGCTCGCGCGCAGCGGGCCGGCGGCTATGTCGGATGTCTT
GGCTCAACCTGA

Upstream 100 bases:

>100_bases
GCGGTCAAGATGCTCCGGGTTGTTTATAGTTGCCAGTGGAATGGGCTGCCGGTATGCCGGAACGAAGAAAATGCAGGAGC
ACGGCTTGGAGGCACCGGCA

Downstream 100 bases:

>100_bases
TGGTCAAGCGCGGAGCGTCCATAGGCCTTTTCGGCATTTTTGGCCGGTCGGAGGATATGCGCCGGCTGGACGAGGCGTTG
CGGCGGTCAGGCATTCATCC

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MEAERRPGPVRRRRRSGLAGRFANRLVRAAVLVAIVPLVLTLIYCLPFVHPVSTLMLADLATLRGYERQWTPLEEAGRNV
IHSVMMSEDGQFCSHRGIDLGELKAAINEALSGERTRGASTIPMQTVKNLYLWPGRSFLRKAIEAPLAIYLDAVMPKHRI
MEIYLNIAEWGPGIYGVEAAAQHYFGRPSRDLSRREAALLAVTLPNPSERNPAQPSAALRRLASVVEARAQRAGGYVGCL
GST

Sequences:

>Translated_243_residues
MEAERRPGPVRRRRRSGLAGRFANRLVRAAVLVAIVPLVLTLIYCLPFVHPVSTLMLADLATLRGYERQWTPLEEAGRNV
IHSVMMSEDGQFCSHRGIDLGELKAAINEALSGERTRGASTIPMQTVKNLYLWPGRSFLRKAIEAPLAIYLDAVMPKHRI
MEIYLNIAEWGPGIYGVEAAAQHYFGRPSRDLSRREAALLAVTLPNPSERNPAQPSAALRRLASVVEARAQRAGGYVGCL
GST
>Mature_243_residues
MEAERRPGPVRRRRRSGLAGRFANRLVRAAVLVAIVPLVLTLIYCLPFVHPVSTLMLADLATLRGYERQWTPLEEAGRNV
IHSVMMSEDGQFCSHRGIDLGELKAAINEALSGERTRGASTIPMQTVKNLYLWPGRSFLRKAIEAPLAIYLDAVMPKHRI
MEIYLNIAEWGPGIYGVEAAAQHYFGRPSRDLSRREAALLAVTLPNPSERNPAQPSAALRRLASVVEARAQRAGGYVGCL
GST

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=168, Percent_Identity=42.2619047619048, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI87082258, Length=141, Percent_Identity=37.5886524822695, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786343, Length=172, Percent_Identity=35.4651162790698, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788867, Length=198, Percent_Identity=28.2828282828283, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_MESSB (Q11CS6)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_675964.1
- ProteinModelPortal:   Q11CS6
- SMR:   Q11CS6
- STRING:   Q11CS6
- GeneID:   4181473
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3428
- NMPDR:   fig|266779.1.peg.1102
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   MMSEDGQ
- PhylomeDB:   Q11CS6
- ProtClustDB:   PRK00056
- BioCyc:   MSP266779:MESO_3428-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 26809; Mature: 26809

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c74c50c)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAERRPGPVRRRRRSGLAGRFANRLVRAAVLVAIVPLVLTLIYCLPFVHPVSTLMLADL
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATLRGYERQWTPLEEAGRNVIHSVMMSEDGQFCSHRGIDLGELKAAINEALSGERTRGAS
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
TIPMQTVKNLYLWPGRSFLRKAIEAPLAIYLDAVMPKHRIMEIYLNIAEWGPGIYGVEAA
CCCHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHH
AQHYFGRPSRDLSRREAALLAVTLPNPSERNPAQPSAALRRLASVVEARAQRAGGYVGCL
HHHHCCCCCHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEC
GST
CCH
>Mature Secondary Structure
MEAERRPGPVRRRRRSGLAGRFANRLVRAAVLVAIVPLVLTLIYCLPFVHPVSTLMLADL
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATLRGYERQWTPLEEAGRNVIHSVMMSEDGQFCSHRGIDLGELKAAINEALSGERTRGAS
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
TIPMQTVKNLYLWPGRSFLRKAIEAPLAIYLDAVMPKHRIMEIYLNIAEWGPGIYGVEAA
CCCHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHH
AQHYFGRPSRDLSRREAALLAVTLPNPSERNPAQPSAALRRLASVVEARAQRAGGYVGCL
HHHHCCCCCHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEC
GST
CCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA